• Title/Summary/Keyword: scales

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Peptides-derived from Scales of Branchiostegus japonicus Inhibit Ultraviolet B-induced Oxidative Damage and Photo-aging in Skin Cells (피부세포에서 옥돔 비늘로부터 추출한 펩타이드의 UVB에 대한 산화적 손상 및 광 노화 억제)

  • Oh, Min Chang;Kim, Ki Cheon;Ko, Chang-ik;Ahn, Yong Seok;Hyun, Jin Won
    • Journal of Life Science
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    • v.25 no.3
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    • pp.269-275
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    • 2015
  • Collagen peptides, which are found at high concentrations in the human body, are present in animal bones and the skin of marine organisms, namely, fish scales. Collagen is the most abundant structural protein of various connective tissues in animals. Furthermore, it is widely used in biomedical material, pharmaceutical, cosmetic, food, and leather industries. Peptides extracted from scales of various fish protect against ultraviolet B (UVB)-induced skin damage and photo-aging. However, the protective effects of collagen peptides derived from the scales of Branchiostegus japonicus against UVB exposure are unclear. This study investigated the effects of peptides larger than 1 kDa (high-molecular weight peptides [HMP]) and smaller than 1 kDa (low-molecular weight peptides [LMP]), derived from extracts of B. japonicus scales, against UVB-induced skin damage and photo-aging. These peptides scavenged 1,1-diphenyl-2-picrylhydrazyl radicals in a dose-dependent manner. In UVB-exposed HaCaT human keratinocytes, LMP inhibited 8-isoprostane generation, a marker of cellular lipid peroxidation. The peptides also suppressed the UVB-induced increase in tyrosinase activity and melanin content in B16F10 mouse melanoma cells. In addition, the LMP and HMP treatment suppressed UVB-induced elastase and matrix metalloproteinase-1 activities in the HaCaT cells. These results indicate that peptides derived from B. japonicus scales have antioxidant, antiphoto-aging, and skin-whitening effects.

Effect of Inorganic Salts in MS Medium, Sucrose, and Activated Charcoal on Bulblet Formation from in Vitro Bulbscales in Lilium Oriental Hybrid 'Casa Blanca' (MS 배지 무기물, 당 및 활성탄의 농도가 Lilium Oriental Hybrid 'Casa Blanca'의 기내인편으로부터 자구형성에 미치는 영향)

  • 한봉희;예병우;구대회;고재영
    • Korean Journal of Plant Tissue Culture
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    • v.26 no.2
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    • pp.103-107
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    • 1999
  • The effects of MS salt strength, sucrose, and cultural conditions on bulblet formation and growth were investigated to optimize the conditions for micropropagating bulblets from in vitro bulb scales of Lilium Oriental Hybrid 'Casa Blanca'. There was no difference on bulblet formation in the range of 1/2~2 $\times$ strength of MS salt, but it was inhibited remarkably in 3 $\times$ strength of MS salt. The growth of regenerated bulblets was most stimulated on MS basal medium. Favorable bulblet formation and its growth from bulb scales were achieved when grown on the media with 1 : 2 or 1 : 3 in the ratio of NH$_4$^+ : NO$_3$^- , as well as on MS basal medium (NH$_4$^+ : NO$_3$^- = about l : 2). Therefore, MS basal medium was very suitable for bulblet formation and growth from bulb scales. Bulblet formation was inhibited but its growth was stimulated with increase sucrose concentration in the medium. The growth of regenerated bulblets was very effective on the media with 9~12% sucrose. Addition of activated charcoal (AC) to the medium inhibited bulblet formation from bulb scales, but enhanced the growth of regenerated bulblets. Especially, the medium containing 1 g/L AC was most effective on the growth of bulblets. No difference was found on bulblet formation and growth from bulb scales under light and dark conditions. In vitro micropropagation of L. Oriental Hybrid 'Casa Blanca' was supposed very reasonable to enhance the growth of the bulblets after forming of bulblets from in vitro bulb scales, and then, subculture the bulb scales from the grown bulblets on MS medium with 9% sucrose and 1 g/L AC.

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Reliability and Validity of Korean Version of the SWAL-QOL (한국판 SWAL-QOL의 신뢰도와 타당도)

  • Kim, Se-Yun;Cha, Yu-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.5
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    • pp.2981-2988
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    • 2014
  • The Purpose of the this study was to identify reliability and validity of the Korean version of the Swallowing Quality of Life questionnaire(KSWAL-QOL). The study was performed in 71 patients diagnosed dysphagia by videofluoroscopy and 80 healthy swallowers. The reliability was good with a Cronbach's ${\alpha}$ and intraclass correlation coefficient of .86~.96 and .80~.93, respectively. The Pearson product moment correlation coefficients between KSWAL-QOL scales ranged from .17~.74 which was showed significant correlation. Healty swallowers scored higher than dysphagic patients on all scales and statistically significant differences were observed across all the scales between healthy swallowers and dysphagic patients(p<.01). Tube feeders scored lower than non-tube feeders on all scales and statistically significant differences were observed in all the scales except sleep(p<.05). There are significant difference between diet steps in all scales except eating desire, communication, fear and people on diet fourth step feeding had the highest scores on the all scales(p<.05). Because KSWAL-QOL seems to be a reliable and valid tool, it is considered to be appropriate as a tool to measure quality of life of patient with swallowing disorder.

Characterization of Oxide Scales Formed on Fe3Al, Fe3Al-Cr, Fe3Al-Cr-Mo, Ni3Al and Ni3Al-Cr Alloys (Fe3Al, Fe3Al-Cr, Fe3Al-Cr-Mo, Ni3Al 및 Ni3Al-Cr 합금표면에 형성된 산화물 특성분석)

  • Shim, Woung-Shik;Lee, Dong-Bok
    • Korean Journal of Materials Research
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    • v.12 no.11
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    • pp.845-849
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    • 2002
  • Alloys of $Fe_3$Al, $Fe_3$Al-6Cr, $Fe_3$Al-4Cr-1Mo, $Ni_3$Al, and $Ni_3$Al-2.8Cr were oxidized at $1000^{\circ}C$ in air, and the oxide scales formed were studied using XRD. SEM, EPMA, and TEM. The oxide scales that formed on $Fe_3$Al-based alloys consisted primarily of $\alpha$-$Al_2$$O_3$ containing a small amount of dissolved Fe and Cr ions, whereas those that formed on $Ni_3$Al-based alloys consisted primarily of $\alpha$-$Al_2$$O_3$, together with a small amount of $NiAl_2$$O_4$, NiO and dissolved Cr ions. For the entire alloys tested, nonadherent oxide scales formed, and voids were inevitably existed at the scale-matrix interface.

A SIMPLIFIED TREATMENT OF GRAVITATIONAL INTERACTION ON GALACTIC SCALES

  • Trippe, Sascha
    • Journal of The Korean Astronomical Society
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    • v.46 no.1
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    • pp.41-47
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    • 2013
  • I present a simple scheme for the treatment of gravitational interactions on galactic scales. In anal- ogy with known mechanisms of quantum field theory, I assume ad hoc that gravitation is mediated by virtual exchange particles-gravitons-with very small but non-zero masses. The resulting den- sity and mass profiles are proportional to the mass of the gravitating body. The mass profile scales with the centripetal acceleration experienced by a test particle orbiting the central mass, but this comes at the cost of postulating a universal characteristic acceleration $a_0{\approx}4.3{\times}10^{-12}msec^{-2}$ (or $8{\pi}a_0{\approx}1.1{\times}10^{-10}msec^{-2}$). The scheme predicts the asymptotic flattening of galactic rotation curves, the Tully-Fisher/Faber-Jackson relations, the mass discrepancy-acceleration relation of galaxies, the surface brightness-acceleration relation of galaxies, the kinematics of galaxy clusters, and "Renzo's rule" correctly; additional (dark) mass components are not required. Given that it is based on various ad-hoc assumptions and given further limitations, the scheme I present is not yet a consistent theory of gravitation; rather, it is a "toy model" providing a convenient scaling law that simplifies the description of gravity on galactic scales.

A Case Report for PTSD Patients Based on Mindfulness & I-Jeong-Byeon-Gi Therapy (마음챙김 명상과 이정변기요법을 이용한 PTSD 환자 치험례)

  • Park, Jong-Min;Lee, Go-Eun;Sue, Joo-Hee;Bae, Dal-Bit;Choi, Sung-Youl;Kang, Hyung-Won
    • Journal of Oriental Neuropsychiatry
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    • v.25 no.1
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    • pp.73-84
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    • 2014
  • The purpose of this study was to introduce a PTSD patient who experienced significant effects of mindfulness meditation and Ii-Gyeung-Byun-Qi therapy. Our psychotherapy was executed five times a week for the 14-year-old male patient who attended middle school and was diagnosed by DSM-IV Diagnostic Criteria for PTSD, and then the MMPI-A was evaluated to determine the effects after 3 months. The results showed normal profiles of MMPI-A validity scales and Clinical Scales profile after his treatment, positive changes in content scales, and significant decreases of PSYC (psychoticism) and NEGE (negative emotionality) in PSY-5 scales. This study made through a case report on the treated psychotherapy for PTSD by the applications of modern psychological techniques in the Korean psychotherapy. We expected that this case report will have a role in development of standardized psychotherapy programs for PTSD.

The Validity of a Single Item Scale - Health Related Quality of Life in Heart Failure Patients - (단일 문항 척도의 타당도 조사 - 심부전 환자의 건강관련 삶의 질을 중심으로 -)

  • Kim, Yong-Suk
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.16 no.4
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    • pp.490-496
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    • 2009
  • Purpose: The purpose of this study was to examine the validity of a single item scale by comparing a single item scale of health related quality of life to subscopes of the multi-item scales in the Medical Outcome Study Short Form-36 (SF-36), and Minnesota Living with Heart Failure Questionnaire (MLHFQ). Method: The data from 103 patients with heart failure were analyzed. The statistics program SPSS 12.0 used for descriptive statistics. Results: Significant correlations were found between the single item scale and subscopes of SF-36, for physical functioning (r= .42), role physical (r= .22), general health perception (r= .46), vitality (r= .40), social functioning (r= .20) and mental health (r= .51), but not for body pain (r= .12) and role emotional (r= .06). Physical (r= -.41), emotional (r= -.49) and total scores (r= -.49) of MLHFQ were significantly related to the single item scale. Conclusion: The single item scale of health related quality of life showed low to moderate correlation with multi-item scales. Even though the single item scale was correlated with several subscopes of multi-item scales, the correlation was not high, so we have to use caution when using the single item scale instead of multi-item scales.

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Study about Personality Traits of Oriental Medical Students in Graduating Class on MMPI (1) (MMPI에 나타난 한의대 졸업반 학생의 성격특성에 대한 연구(1))

  • Lee, Dong-Wha;Kim, Bo-Kyung
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.3
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    • pp.217-227
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    • 2009
  • Objectives : The purpose of this study was to investigate personality traits of oriental medical students in graduating class by using the Minnesota Multiphasic Personality Inventory (MMPI). Methods : The subjects of this study were 164 (male 108, female 56) oriental medical students in Busan. MMPI scores were analyzed about validity scales, clinical scales and personality disorder scales in aspects of whole student, attendant year, gender and ages. Results & Conclusions : First, The average scores of MMPI scales showed that oriental medical students in graduating class lay within the range of normal. There was no difference among attendant years, and averages of each year made little difference to whole student. The students belonged to 'defensive group' that were doing adaptive defense relatively Second, in comparison with gender, female students got more social adaptability and less stress than male students. In comparison with ages, group of $28{\sim}42$ years old tended to make up themselves with defensive attitude.

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A Study on Development of Semantic Differential Scales for Visual Evaluation of Flare Skirt (플레어스커트의 시각적 평가를 위한 의미미분척도 개발)

  • Lee, Jung-Soon;Han, Gyung-Hee
    • Journal of Fashion Business
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    • v.13 no.1
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    • pp.91-101
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    • 2009
  • The purpose of this study is to develop semantic differential scales which are necessary to evaluate visual image and effect of flare skirt. As a result of the first survey of 362 female college students, the most effective factors for shape of flare skirt are silhouette, volume of flare, and skirt length. Based on this result, we made flare skirt simulation for visual evaluation with using I-Designer program. 4 kinds of volume of flare($90^{\circ},\;180^{\circ},\;270^{\circ},\;360^{\circ}$) and 3 kinds of skirt length(48cm, 58cm, 68cm) are combined as variables for flare skirt of visual evaluation. For the second survey of 362 female college students, we asked to write suggested adjectives freely. As a result, we could draw out 210 adjectives. 'Feminine' was most frequently used word for flare skirt, and then, 'vivid', 'rhythmic', 'cute', 'soft', 'fat', and 'comfortable' in this order. With considering frequently used words in the preceding study, we selected 41 adjectives. Antonyms were selected from the resulted frequency of this study and preceding study, and the rest of words were found from dictionary. From these process, we developed semantic differential scales for visual image and effect of flare skirt.

Comparison of CES-D and RADS-2-K in Measuring Adolescent Depression (청소년 우울 측정을 위한 CES-D와 RADS-2-K 도구의 비교)

  • Sung, Kyung Mi
    • Journal of the Korean Society of School Health
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    • v.29 no.2
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    • pp.53-62
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    • 2016
  • Purpose: The purpose of this study was to compare the scales measuring adolescent depression. Methods: A cross-sectional survey was conducted using CES-D and RADS-2-K as sales measuring adolescent depression. The participants were 1,217 adolescents from two middle schools located in South Korea. Data were analyzed using SPSS/WIN 21.0. All the items included in the two instruments were analysed through content analysis. Results: The study revealed that the two instruments produced different results in the number of depressive students, depression levels according to subjects' characteristics, and item distribution based on content analysis. The total number of the students belonging to the depression group was 194, including 132 from CES-D and 183 from RADS-2-K. Based on the content analysis covering two categories, general and adolescent depression, the study determined fifteen subcategories in the items of the two scales. Conclusion: In this study, CES-D showed less sensitivity than RADS-2-K in depression levels according to factors relevant to adolescent depression, and both scales had no item for three subcategories of adolescent depression and one subcategory of general depression. The researcher suggests that further studies to evaluate the validity of adolescent depression scales will be useful for helping adolescents with depression.