• 폴리머
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• 제35권4호
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• pp.284-288
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• 2011

초임계 유체에서 poly(L-Lactide) (PLLA)의 산업화 생산 공정 개발을 위한 예비 연구로 1-dodecano/stannous 2-ethyl-hexanoate(DoOH/Sn(Oct)$_2$)를 개시제로 하여 chlorodifluoromethane 초임계 용매 하에서 락티드의 개환 중합을 실시하였다. 중합은 3 L 반응기를 사용하였으며 중합시간, 온도, 압력 및 단량체와 초임계 용액 농도에 따른 중합거동을 관찰하였다. 중합시간이 5시간 경과할 경우 얻어진 중합체의 반응 수율 및 분자량은 각각 72%, 68000 g/mol이었다. 단량체의 농도가 증가할수록 중합체의 수율 및 분자량은 증가하였으며 최대 각각 97%, 144000 g/mol이 얻어졌다. 반응기의 압력이 130에서 240 bar로 증가할 경우 PLLA의 수율 및 분자량이 증가하였다. 얻어진 중합체의 열안정성을 향상시키기 위해 메탄올 처리 및 진공 처리를 실시하였다. 그 결과 두 가지 방법 모두 PLLA의 열안정성을 향상시켰다.

• Nuclear Engineering and Technology
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• 제49권7호
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• pp.1451-1456
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• 2017

Finding technical issues associated with equipment scale-up is an important subject for the investigation of pyroprocessing. In this respect, electrolytic reduction of 1 kg $UO_2$, a unit process of pyroprocessing, was conducted using graphite as an anode material to figure out the scale-up issues of the C anode-based system at pilot scale. The graphite anode can transfer a current that is 6-7 times higher than that of a conventional Pt anode with the same reactor, showing the superiority of the graphite anode. $UO_2$ pellets were turned into metallic U during the reaction. However, several problems were discovered after the experiments, such as reaction instability by reduced effective anode area (induced by the existence of $Cl_2$ around anode and anode consumption), relatively low metal conversion rate, and corrosion of the reactor. These issues should be overcome for the scale-up of the electrolytic reducer using the C anode.

• Journal of Electrical Engineering and Technology
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• 제13권5호
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• pp.2050-2058
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• 2018

Impulse characteristic of transmission tower grounding grid is needed for lightning protection of transmission line. This paper describes an outdoor experimental test facility established for large-scale grounding grid of transmission tower, made up of four impulse current generators and a circle current return electrode. The amplitude of impulse current is up to 100 kA. The results of the CDEGS simulation and GPR measurement reveal the uniform current distribution in the test arrangement. An impulse test for a square electrode with extended conductors is carried out in condition of three current waveforms with different amplitude. Based on the electrical network model and iterative algorithm method, a calculation model is proposed to simulate the impulse characteristic of large-scale grounding grid considering soil ionization. The curve of impulse resistance against the current amplitude shows the soil ionization both from the simulation and test. Deviation between the simulation and test result is less than 15%.

• Journal of Microbiology and Biotechnology
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• 제31권3호
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• pp.349-357
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• 2021

Monoclonal antibodies are widely used as diagnostic reagents and for therapeutic purposes, and their demand is increasing extensively. To produce these proteins in sufficient quantities for commercial use, it is necessary to raise the output by scaling up the production processes. This review describes recent trends in high-density cell culture systems established for monoclonal antibody production that are excellent methods to scale up from the lab-scale cell culture. Among the reactors, hollow fiber bioreactors contribute to a major part of high-density cell culture as they can provide a tremendous amount of surface area in a small volume for cell growth. As an alternative to hollow fiber reactors, a novel disposable bioreactor has been developed, which consists of a polymer-based supermacroporous material, cryogel, as a matrix for cell growth. Packed bed systems and disposable wave bioreactors have also been introduced for high cell density culture. These developments in high-density cell culture systems have led to the monoclonal antibody production in an economically favourable manner and made monoclonal antibodies one of the dominant therapeutic and diagnostic proteins in biopharmaceutical industry.

• KSBB Journal
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• 제24권1호
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• pp.89-95
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• 2009

Biodiesel (fatty acid alkyl esters), which is produced from sustainable resources such as vegetable oil, animal fat and waste oils, have used to as substitutes for petro-diesel. In this study, we investigate the performance of 30 L and 300 L pilot-scale biodiesel production system using alkali-catalyst transesterification from soybean oil and rapeseed oil produced at Jeju island in Korea. The 30 L-scale biodiesel production was performed to in the condition of reaction temperature $65^{\circ}C$, catalyst amount 1% (w/w) and oil to methanol molar ratio 1 : 8. At that reaction condition, the fatty acid methyl ester contents of product are above 98% within reaction time 30 min. Also, the conversion yield of over 98% was obtained in 300 L-scale biodiesel production system using rapeseed oil and soybean oil. The quality of biodiesel produced from reaction system was satisfied to recommended quality standard of Korea. Our results may provide useful information with regard to the scale-up of more economic and efficient biodiesel production process.

• 시스템엔지니어링학술지
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• 제18권2호
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• pp.11-23
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• 2022

Although artificial intelligence(AI) is a key technology in the digital transformation among the emerging technologies, there are concerns about the use of AI, so many countries have been trying to set up a proper regulation system. This study analyzes the cases of the regulation policies on AI in USA, EU and Korea with the aim to set up and improve proper AI policies and strategies in Korea. In USA, the establishment of the code of ethics for the use of AI is led by private sector. On the other side, Europe is strengthening competitiveness in the AI industry by consolidating regulations that are dispersed by EU members. Korea has also prepared and promoted policies for AI ethics, copyright and privacy protection at the national level and trying to change to a negative regulation system and improve regulations to close the gap between the leading countries and Korea in AI. Moreover, this study analyzed the course of policy changes of AI regulation policy centered on ACF(Advocacy Coalition Framework) model of Sabatier. Through this study, it proposes hyper-scale AI regulation policy recommendations for improving competitiveness and commercialization in Korea. This study is significant in that it can contribute to increasing the predictability of policy makers who have difficulties due to uncertainty and ambiguity in establishing regulatory policies caused by the emergence of hyper-scale artificial intelligence.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2004년도 제5회 압연심포지엄 신 시장 개척을 위한 압연기술
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• pp.277-284
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• 2004

Low carbon steels containing Si of up to $1.2\;wt\%$ were oxidized in air at 1373 K and 1523 K, i.e. below and above the eutectic temperature of FeO and $Fe_2SiO_4$. The influence of a impurity element, S on behavior of scale formation during oxidation was investigated by using $M\"{o}chssbauer$ spectroscopy and EDS. This allowed establishment of an interface oxidation model of Si-added steel depending on temperature and an impurity element. A compound of FeO and FeS was formed in the scale/matrix interface of low carbon steels containing S of up to $0.03\;wt\%$ oxidized above 1213 K of the eutectic temperature. This was flat formed between $Fe_2SiO_4$ nodules along the scale/matrix interface without selective oxidation. It is due to low viscosity and high wettability of the compound of FeO and FeS in liquid. Conventional metallographic examinations revealed that roughness of the scale/matrix interface in Si-added steels became flat as the content of S increased. It was independent of oxidizing temperature and Si content. Effects of oxidizing temperature and an impurity element content on descaling characteristics in Si-added steels were evaluated by using a hydraulic descaling simulator. Good descaling characteristics was attributable to this flatness of the scale/matrix interface.

• 한국도로학회논문집
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• 제20권2호
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• pp.9-17
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• 2018

PURPOSES : The frequency and severity of natural disasters such as torrential rain or typhoons have become increasingly significant worldwide. Events such as summer typhoons and localized torrential downpour can cause severe damages to a residential area and road networks, resulting in serious harm to the daily lives of people, especially in rural areas by isolating residents from road networks. An immediate and emergency repair technology for the collapsed road networks is urgently needed. This study introduces a new technology to repair road bases or slopes. METHODS : The development of new technology for emergency and permanent repair consists of first, packing of cement paste-coated gravel, second, combining appropriate equipment, and third, conducting a field applicability test. In this research, the compressive strength of cement pastecoated gravel, gravel-netting concrete properties, and packing efficiency were determined, and a full scale field mock-up test was carried out. RESULTS : The compressive strength of the cement paste-coated gravel concrete satisfied the required limit for road base of 5 MPa after 7 days. With appropriate netting materials and packing size, gravel-netting concrete was successful up to a slope of 1:1.5. The full scale field mock-up test showed efficiency in the field and penetration resistance performance. CONCLUSIONS : The new technology of emergency and permanent repair for damaged road bases and slopes, introduced in this study, showed satisfactory performance. The technology is expected to be applied in the field when construction procedures and quality specifications are made.

• 센서학회지
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• 제28권6호
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• pp.360-365
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• 2019

A polyvinylidene fluoride (PVDF)-based film speaker is successfully fabricated with enhanced bass sound by incorporating buckled nanospring carbon nanotubes (NS-CNTs) as fillers. Various concentrations up to 1-7 wt% of uniformly dispersed buckled NS-CNTs are loaded to increase the beta (β)-phase fraction, crystallinity, and dielectric constant of the speaker, and this results in the bass part enhancement of about 19 dB full scale (dBFS) at 7 wt% filler loading of the piezoelectric film speaker.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2018년도 춘계 학술논문 발표대회
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• pp.66-67
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• 2018

Large-scale construction projects require various license and technologies for the manufacturing and handling processes. Also, the whole life cycle business process management determines the success of the project. Then, the efficiency of the business conducted by stakeholders and their possessed technology should be enhanced in order to strengthen their competitive power. For this reason, many experts pointed out to focus on the improvement of the life cycle process and efficient management. Since it is very important to keep up-to-date data and utilize it for work during the long-term project to reflect changes in the large-scale project, the most important part of the project management in project is information change management. Therefore, the objective of this study is applying configuration management(CM) technique in order to managing change data generated for planning in early phase. The result of this research will certainly assist the large-scale project managers in the development of information change management system.