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Scale-up Polymerization of L -Lactide in Supercritical Fluid  

Prabowo, Benedictus (Department of Chemistry, Korea University)
Kim, Se-Yoon (Biomaterials Research Center, Korea Institute of Science and Technology)
Choi, Dong-Hoon (Department of Chemistry, Korea University)
Kim, Sao-Hyun (Biomaterials Research Center, Korea Institute of Science and Technology)
Publication Information
Polymer(Korea) / v.35, no.4, 2011 , pp. 284-288 More about this Journal
Abstract
For the purpose of the pre-industry production of poly(L-lactide) (PLLA) and full understanding of the supercritical polymerization system, large scale polymerization of L-iactide initiated by 1-dodecano/stannous 2-ethyl-hexanoate (DoOH/Sn(Oct)$_2$) was carried out in supercritical chlorodifluoromethane under various reaction conditions (time, temperature and pressure)and reactants (monomer and supercritical solvent) concentrations. A 3 L sized-reactor system was used throughout this study. The monomer conversion increased to 72% on increasing reaction time to 5 h. The molecular weight of PLLA product also increased to 68000 g/moi over the same period. An increase in monomer concentration resulted in a higher molecular weight, up to 144000 g/mol and 97% of monomer conversion. Raising the reaction pressure from 130 to 240 bar also resulted in an increased monomer conversion and molecular weight. To increase heat resistivity of PLLA, methanol treatment and heat-vacuum methods were evaluated. Both of them successfully improved the heat resistivity property of PLLA.
Keywords
large scale polymerization; polylactide; supercritical fluid;
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1 T. Asno and W. J. le Noble, Chem. Rev., 78, 407 (1978).   DOI
2 R. Van Eldik, T. Asno, and W. J. le Noble, Chem. Rev., 89, 549 (1989).   DOI
3 H. S. Byun, Polymer(Korea), 23, 181 (1999).
4 J. W. Pack, S. H. Kim, S. Y. Park, and Y. W. Lee, Macromol. Biosci., 4, 340 (2004).   DOI   ScienceOn
5 J. W. Pack, S. H. Kim, S. Y. Park, Y. W. Lee, and Y. H. Kim, Macromolecules, 36, 8923 (2003).   DOI   ScienceOn
6 Y. Doi and K. Fukuda, Proceedings of the Third International Scientific Workshop on Biodegradable Plastics and Polymers, Japan, p.464 (1994).
7 J. W. Pack, S. H. Kim, S. Y. Park, Y. W. Lee, and Y. H. Kim, Macromolecules, 37, 3564 (2004).   DOI   ScienceOn
8 Z. H. Zhou, X. P. Liu, and L. H. Liu, Int. J. Polym. Mater., 57, 532 (2008).   DOI   ScienceOn
9 Y. He, Z. Fan, J. Wei, and S. Li, Polym. Eng. Sci., 46, 1583 (2006).   DOI   ScienceOn
10 A. A. Clifford, Fundamentals of Supercritical Fluids, Oxford University Press, Oxford, p.189 (1998).
11 S. Alsoy and J. L. Duda, Chem. Eng. Technol., 22, 971 (1999).   DOI   ScienceOn
12 J. C. Middleton and A. J. Tipton, Biomaterials, 21, 2335(2000).   DOI   ScienceOn
13 A. I. Cooper, J. Mater. Chem., 10, 207 (2000).   DOI   ScienceOn
14 D. L. Tomasko, H. Li, D. Liu, X. Han, M. J. Wingert, and L. Lee, J. Ind. Eng. Chem. Res., 42, 6431 (2003).   DOI   ScienceOn
15 J. L. Kendall, D. A. Canelas, J. L. Young, and J. M. De Simone, Chem. Rev., 99, 543 (1999).   DOI   ScienceOn