• Asian Pacific Journal of Cancer Prevention
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• v.15 no.20
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• pp.8709-8713
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• 2014

Background: Previous studies have indicated that single nucleotide polymorphisms (SNPs) of the interleukin-17 (IL-17) gene are associated with an increased risk of gastric cancer. However, the findings were inconsistent. Materials and Methods: To provide a more reliable estimation of the association between SNPs in the IL-17 gene and the susceptibility to gastric cancer, we searched PubMed, CNKI, and Wan Fang databases and selected finally six studies covering 2,366 cases and 3,205 controls to perform a meta-analysis. Results: Statistical analyses showed that an rs2275913 polymorphism within the IL-17A gene was significantly associated with an increased risk of gastric cancer using a generalized odds ratio (ORG, a model-free approach). Moreover, we also found that the 'A' allele carriers of IL-17A rs2275913 had a significant link with clinicopathological features. However, no significant positive signals were observed in the association analysis of the rs3748067 and rs763780 polymorphisms with the risk of gastric cancer in IL-17A and IL-17F, respectively. Conclusions: Despite some limitations, the present meta-analysis provided a more precise estimation of the relationship between the IL-17 gene SNPs and gastric cancer risk compared with individual studies.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2008.11a
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• pp.517-520
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• 2008

The city refreshing development projects in the domestic recently have been performed under leading of public institution laying stress on new city and existing urban district. These development projects are still staying in safety control level despite risk factor management at preliminary estimation stage has been more important factor to success and add value creation. Understanding inaccurately about various risk analysis techniques that can analyze risk factors and the insufficient application of step that can analysis technique s could make projects more difficult. Therefore, this research suggests the more effective methods for risk analysis that can control the risks in the pre-project evaluation stage.

• Korean Journal of Construction Engineering and Management
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• v.4 no.4 s.16
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• pp.201-211
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• 2003

Considering about construction projects characteristics, there Is an existing uncertainty which causes inaccuracy or invalidity under decision making situation. Therefore, cost risk analysis of numerous construction projects are Inclined to depend on expert's experiences and subjective judgements. In Korean domestic construction works, however, there is no reasonable method or process for applying subjective elements. Only probabilistic analysis using objective calculation are being used now. This research suggests a cost risk analysis method to analyze quantitatively Cost Impact by risk, and it appraises expert's subjective elements for the purpose of enhancing validity of cost estimation. Moreover, a new cost risk analysis method is introduced for providing convenient user interface in practical business.

• Nuclear Engineering and Technology
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• v.47 no.4
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• pp.461-471
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• 2015

Recently, the estimation of the social cost of energy sources has been emphasized as various novel energy options become feasible in addition to conventional ones. In particular, the social cost of introducing measures to protect power-distribution systems from power-source instability and the cost of accident-risk response for various power sources must be investigated. To account for these risk factors, an integrated societal risk assessment framework, based on power-uncertainty analysis and accident-consequence analysis, is proposed. In this study, we applied the proposed framework to nuclear power plants, solar photovoltaic systems, and wind-turbine generators. The required capacity of gas-turbine power plants to be used as backup power facilities to compensate for fluctuations in the power output from the main power source was estimated based on the performance indicators of each power source. The average individual health risk per terawatt-hours (TWh) of electricity produced by each power source was quantitatively estimated by assessing accident frequency and the consequences of specific accident scenarios based on the probabilistic risk assessment methodology. This study is expected to provide insight into integrated societal risk analysis, and can be used to estimate the social cost of various power sources.

• Journal of Construction Engineering and Project Management
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• v.3 no.2
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• pp.49-57
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• 2013

A sea dike construction has been increased in Korea because of the actively deployed reclamation project in basis of efficient application in land. The degree of completion in sea dike construction is affected by final closing construction, which has a lot of uncertainty that often results in higher accidents rate. Therefore, this research identified risk factors of final closing construction and classified them. This research examines the likelihood and its impact for each risk factor and calculates the risk degree as to the risk matrix. Based on this, the impact and the environmental conditions that affect to risk factors are investigated and further responsive methods are established for each risk factor. Ultimately, this research attempts to provide the risk retrenchment method for inspectors by proposing risk estimation model, responsive action list, and risk management process.

• International Journal of Highway Engineering
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• v.11 no.3
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• pp.61-74
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• 2009

Traffic accident risk index Computation model's development apply traffic level of significance about area of road user group, road and street network area, population group etc.. through numerical formula or model by countermeasure to reduce the occurrence rate of traffic accidents. Is real condition that is taking advantage of risk by tangent section through estimation model and by method to choose improvement way to intersection from outside the country, and is utilizing being applied in part business in domestic. However, question is brought in the accuracy being utilizing changing some to take external model in domestic real condition than individual development of model. Therefore, selection intersection estimation element through traffic accidents occurrence present condition, geometry structure, control way, traffic volume, turning traffic volume etc. in 96 intersections in this research, and select final variable through correlation analysis of abstracted estimation elements. Developed intersection design model taking advantage of signal type, numeric of lane, intersection type, analysis of variance techniques through ANOVA analysis of three variables of intersection form with selected variable lastly, in signal crossing through three class intersection, distinction variable choice risk in model, no-signal crossing risk distinction analysis model and so on develop.

• The Journal of Fisheries Business Administration
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• v.34 no.1
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• pp.31-44
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• 2003

The purpose of this study is to investigate empirically interaction among the financing decision, investment decision, and profitability by using 41 fisheries corporations in Korea, and to suggest implications of the empirical results for government's financial policy for fisheries corporations. Sample period is 19 years from 1982 till 2000. This analysis method employs the two stage least squares(2SLS) estimation method. From the results of regression analysis by 2SLS estimation method, the adjusted $R^2$ values were high and the overall F values indicated significant. The empirical results of this study are as follows; (1) determinant factors of capital structure model for fisheries are profitability, firm-size, fisheries investment of total asset, and business risk. As pecking order theory explains, the higher is profitability the lower is debt ratio. The larger firm-size, the higher is debt ratio. The higher is fisheries investment of total asset and business risk, the higher is debt ratio. (2) determinant factors of investment model for fisheries are the change of sales, business risk, and debt ratio. These factors have positive relation to fisheries investment of total asset (3) determinant factors of profitability model for fisheries are fisheries investment of total asset and debt ratio. These factors have negative relation to profitability. On the basis of analysis results, on the government's financial policy for fisheries corporations, I suggests that with interest rate reduction, the government should lend more funds to solve the crisis in the financial structure of the fisheries firms

• Communications for Statistical Applications and Methods
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• v.21 no.3
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• pp.235-243
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• 2014

Constrained Bayesian estimates overcome the over shrinkness toward the mean which usual Bayes and empirical Bayes estimates produce by matching first and second empirical moments; subsequently, a constrained Bayes estimate is recommended to use in case the research objective is to produce a histogram of the estimates considering the location and dispersion. The well-known squared error loss function exclusively emphasizes the precision of estimation and may lead to biased estimators. Thus, the balanced loss function is suggested to reflect both goodness of fit and precision of estimation. In insurance pricing, the accurate location estimates of risk and also dispersion estimates of each risk group should be considered under proper loss function. In this paper, by applying these two ideas, the benefit of the constrained Bayes estimates and balanced loss function will be discussed; in addition, application effectiveness will be proved through an analysis of real insurance accident data.

• Journal of Environmental Health Sciences
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• v.33 no.1 s.94
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• pp.1-10
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• 2007

This study accomplished to grasp the present condition of HAPs and to examine efficiently carcinogenic and non-carcinogenic health effects through health risk assessment in new apartments from June, 2004 to May,2005. Moreover, we performed uncertainty analysis by Monte-Carlo analysis to control uncertainty of exposure factors. The major results obtained from this study were as follows. Firstly, cancer risk of formaldehyde for male was $1.67{\times}10^{-5}$ in CTE in point estimation. Cancer risk of formaldehyde was showed $2.94{\times}10^{-3}$ in RME that applied worst case used results of 95 percentile in point estimation. It exceeds $10^{-6}$ of guide line in US EPA. Moreover, cancer risks of formaldehyde for female were $3.98{\times}10^{-5}$ in CTE and $3.93{\times}10^{-3}$ RME. Secondly, every hazard index for non-carcinogenic pollutants was less than 1 of permitted standards in CTE. However, in RME of male, hazard indexes of 1,2-Dichloropropane and Toluene were 1.3 and 2.0, respectively. Hazard indexes of 1,2-Dichloropropane and Totuene for female in RME were 1.7 and 2.6, respectively.

• Journal of the Korean Data and Information Science Society
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• v.16 no.3
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• pp.567-580
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• 2005

It is usually assumed that asset returns in the stock market are normally distributed. However, analyses of real data show that the distribution tends to be skewed and to have heavier tails than those of the normal distribution. In this paper, we investigate the method of estimating the value at risk(VaR) of stock returns. The VaR is computed by using the transformation and back-transformation method. The analysis of KOSPI and KOSDAQ data shows that the proposed estimation outperformed that under the normal assumption.