• 제목/요약/키워드: resistance management

검색결과 994건 처리시간 0.024초

Streptococcus parauberis의 퀴놀론 내성 증가와 Topoisomerase 유전자에서의 돌연변이 신속 분석 (Increased Resistance to Quinolones in Streptococcus parauberis and Development of a Rapid Assay for Detecting Mutations in Topoisomerase Genes)

  • 김소연;김영철;정서경;전려진;진지웅;정현도
    • 한국수산과학회지
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    • 제47권3호
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    • pp.247-254
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    • 2014
  • To investigate the acquisition of quinolone resistance, we examined mutations in the quinolone resistance-determining region (QRDR) of type II topoisomerase genes in ciprofloxacin (CIP)-resistant clinical isolates and in vitro mutants of Streptococcus parauberis. The CIP-resistant clinical isolates had one base change responsible for a Ser-79${\rightarrow}$Thr in the QRDR of parC. However, the CIP-resistant in vitro mutants had an altered QRDR of parC (Ser-79${\rightarrow}$Ile) that differed from that of the isolates. None of the CIP-resistant S. parauberis clinical isolates or in vitro mutants exhibited amino acid changes in gyrA or gyrB. However, even though involvement in the increased resistance was not clear, an Arg-449${\rightarrow}$Ser mutation outside of the QRDR of parE was detected in CIP-resistant mutant 2P1. These results suggest that the topoisomerase IV gene, parC (and possibly parE, as well), is the primary ciprofloxacin target in S. parauberis. Additionally we established a high-resolution melting (HRM) assay capable of detecting the dominant mutation in four type II topoisomerase genes conferring ciprofloxacin resistance. These rapid and reliable assays may provide a convenient method of surveillance for genetic mutations conferring antibiotic resistance.

Ultrastructures of Colletotrichum orbiculare in the Leaves of Cucumber Plants Expressing Induced Systemic Resistance Mediated by Glomus intraradices BEG110

  • Jeun, Yong-Chull;Lee, Yun-Jung;Kim, Ki-Woo;Kim, Su-Jung;Lee, Sang-Woo
    • Mycobiology
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    • 제36권4호
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    • pp.236-241
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    • 2008
  • The colonization of an arbuscular mycorrhizal fungus Glomus intraradices BEG110 in the soil caused a decrease in disease severity in cucumber plants after fungal inoculation with Colletotrichum orbiculare. In order to illustrate the resistance mechanism mediated by G. intraradices BEG110, infection patterns caused by C. orbiculare in the leaves of cucumber plants and the host cellular responses were characterized. These properties were characterized using transmission electron microscopy on the leaves of cucumber plants grown in soil colonized with G. intraradices BEG110. In the untreated plants, inter- and intra-cellular fungal hyphae were observed throughout the leaf tissues during both the biotrophic and necrotrophic phases of infection. The cytoplasm of fungal hyphae appeared intact during the biotrophic phase, suggesting no defense response against the fungus. However, several typical resistance responses were observed in the plants when treated with G. intraradices BEG110 including the formation of sheaths around the intracellular hyphae or a thickening of host cell walls. These observations suggest that the resistance mediated by G. intraradices BEG110 most often occurs in the symplast of the host cells rather than in the apoplast. In addition, this resistance is similar to those mediated by biotic inducers such as plant growth promoting rhizobacteria.

Tolerance: An Ideal Co-Survival Crop Breeding System of Pest and Host in Nature with Reference to Maize

  • Kim, Soon-Kwon
    • 한국작물학회지
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    • 제45권1호
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    • pp.59-70
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    • 2000
  • In nature, plant diseases, insects and parasites (hereafter called as "pest") must be co-survived. The most common expression of co-survival of a host crop to the pest can be tolerance. With tolerance, chemical uses can be minimized and it protects environment and sustains host productivity and the minimum pest survival. Tolerance can be applicable in all living organisms including crop plants, lifestocks and even human beings. Tolerant system controls pest about 90 to 95% (this pest control system often be called as horizontal or partial resistance), while the use of chemicals or selection of high resistance controls pest 100% (the most expression of this control system is vertical resistance or true resistance). Controlling or eliminating the pests by either chemicals or vertical resistance create new problems in nature and destroy the co-survial balance of pest and host. Controlling pests through tolerance can only permit co-survive of pests and hosts. Tolerance is durable and environmentally-friend. Crop cultivars based on tolerance system are different from those developed by genetically modified organism (GMO) system. The former stabilizes genetic balance of a pest and a host crop in nature while the latter destabilizes the genetic balance due to 100% control. For three decades, the author has implemented the tolerance system in breeding maize cultivars against various pests in both tropical and temperate environments. Parasitic weed Striga species known as the greatest biological problem in agriculture has even been controlled through this system. The final effect of the tolerance can be an integrated genetic pest management (IGPM) without any chemical uses and it makes co-survival of pests in nature.in nature.

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혁신저항모델을 활용한 중소기업 기술혁신에 따른 SCM시스템 도입 영향 연구 (A Study on the Technological Innovation and Introduction of SCM System of SMEs' Industry Using the Innovation Resistance Model)

  • 오용민;부제만
    • 산업경영시스템학회지
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    • 제44권3호
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    • pp.165-175
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    • 2021
  • As the advent of the Fourth Industrial Revolution and Information Age, companies are in the state of infinite competition due to the rapidly changing technological environment and fierce competition. In this situation companies are making efforts to gain the competitive advantage by introducing information systems. Supply Chain Management (SCM) is considered a method to gain a competitive edge in rapid change. In fact, companies that already have introduced the SCM system are achieving company renovation with positive effects such as increase of sales stock reduction on-time delivery cost reduction and improved efficiency. This study was started to investigate the resistance that occurs in introducing the SCM system for small and medium-sized manufacturing industries that have not yet introduced the SCM system despite the importance of the SCM system, and to check the effect on the intention of the introduction. As the result of this study, the first is that the company has the higher technological innovation, the more positive the effect on Relative advantage Compatibility Perceived risk, Complexity. Second, The compatibility of the SCM system was rejected in innovation resistance, but it is adopted with the highest impact in the introduction intention. In addition, the mediating effect of innovation resistance was also rejected, confirming that if the SCM system is compatible for the company, it doesn't affect the resistance and is the biggest factor to consider in the introduction of the SCM system. Third, the perceived risk of the SCM system doesn't directly affect the intention to introduce, but has an indirect effect when mediation innovation resistance.

보호접지로 활용하기 위한 건축물 구조체의 접지저항 측정분석 (Grounding Resistance Measurement and Analysis of Building Structures for Applying as Safety Earthing)

  • 오세중;김찬오
    • 조명전기설비학회논문지
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    • 제26권8호
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    • pp.50-55
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    • 2012
  • Grounding is very important for electrical safety. But it is very difficult to secure enough space for the installation and management of grounding in the city because of the congestion of the buildings. Therefore, to solve this problem, this paper suggest structure-grounding application taking advantage of building structure as protective grounding. And, to verify its feasibility, this paper shows the result to measure and analyze grounding-resistance of structure for 12 buildings mainly structed in the city.

Mitigating Antibiotic Resistance at the Livestock-Environment Interface: A Review

  • Ma, Zhengxin;Lee, Shinyoung;Jeong, K. Casey
    • Journal of Microbiology and Biotechnology
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    • 제29권11호
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    • pp.1683-1692
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    • 2019
  • The rise of antimicrobial resistance (AR) is a major threat to global health. The food animal industry contributes to the increasing occurrence of AR. Multiple factors can affect the occurrence and dissemination of AR in the animal industry, including antibiotic use and farm management. Many studies have focused on how the use of antibiotics in food-producing animals has led to the development of AR. However, a few effective mitigating strategies for AR have been developed in food-producing animals, especially those exposed to the environment. The aim of this review is to summarize potential strategies applicable for mitigating AR at the environment-livestock interface.

FLOW-VEGETATION-SEDIMENT INTERACTION

  • Dittrich Andreas;Jarvela Juha
    • Water Engineering Research
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    • 제6권3호
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    • pp.123-130
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    • 2005
  • A good understanding of the interaction between flow, vegetation, and sediment is required for successful river restoration and sustainable flood management. The purpose of this paper is to provide a summary of available methods to determine flow resistance of natural rivers with vegetation, and discuss the influence of vegetation on erosion and sedimentation processes. Recently, significant advances have been made, but the effects of vegetation on flow and sediment dynamics are still not fully understood. Possible solutions to close the gaps in the current knowledge are suggested, with special focus directed to the determination of the interactive width between main channel and vegetated floodplains, the flow resistance of flexible vegetation with and without leaves, and the flow over submerged vegetation with low water depth.

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Optimization of Thermal Performance in Nano-Pore Silicon-Based LED Module for High Power Applications

  • Chuluunbaatar, Zorigt;Kim, Nam-Young
    • International Journal of Internet, Broadcasting and Communication
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    • 제7권2호
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    • pp.161-167
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    • 2015
  • The performance of high power LEDs highly depends on the junction temperature. Operating at high junction temperature causes elevation of the overall thermal resistance which causes degradation of light intensity and lifetime. Thus, appropriate thermal management is critical for LED packaging. The main goal of this research is to improve thermal resistance by optimizing and comparing nano-pore silicon-based thermal substrate to insulated metal substrate and direct bonded copper thermal substrate. The thermal resistance of the packages are evaluated using computation fluid dynamic approach for 1 W single chip LED module.

Individual Dispositions, Resistance to Change and Organizational Empathy in the Hospitality Industry when Change Means Implementation of a New IS

  • Kim, Soo Kyung;Lee, Jeonghoon
    • Journal of Information Technology Applications and Management
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    • 제23권1호
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    • pp.25-32
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    • 2016
  • Using a sample of employees in various hospitality organizations, we proposed that individual disposition such as tolerance for ambiguity, positve affectivity, internal locus of control, and self-efficacy, will influence hospitality employees' resitance to change. The results supported hypotheses. Ultimately, we hope the results of this study provide propoer guidelines with hospitality managers and employees to decrease thiere resistance to change such as new IS implementation and thus increase their willingness to adopt in implementing new IS.

중소기업 ESG 경영 도입의도에 영향을 미치는 요인 : 태도의 매개효과 및 종업원 혁신저항성의 조절효과 (A Study on Factors Affecting ESG Management Intentions of Small and Medium Enterprises : Focusing on the Mediating Effect of Attitude and the Moderating Effect of Employees' Innovation Resistance)

  • 이윤효;박경희;정병규
    • 벤처혁신연구
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    • 제6권2호
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    • pp.41-65
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    • 2023
  • 본 연구는 최근 화두가 되고 있는 중소기업의 ESG(환경·사회·지배구조) 경영 도입 의도에 영향을 미치는 요인을 실증적으로 분석하기 위해 수행되었다. 이를 위해 독립변수로 ESG의 유용성과 용이성을 일차적으로 도출하였다. 또한 중소기업에서 의사결정은 CEO의 결정이 매우 절대적이고 필수적이므로 CEO 의지를 도출하였다. 그리고, ESG 경영의 제도적 요인으로 ESG 경영에 관한 고객사의 요구, 정부 지원, 신용평가 반영 등이 중요한 결정 요인으로 판단되어 이를 독립변수로 채택하였다. 이러한 영향 관계에서 태도의 매개효과와 종업원 혁신 저항성의 조절효과도 동시에 분석 하였다. 이를 위해 유효한 368개의 표본을 SPSS 24.0을 활용하여 분석하였다. 매개효과와 조절 효과는 Process Macro 4.0을 사용하여 분석하였다. 실증분석 결과는 다음과 같다. ESG 도입의 유용성과 용이성, CEO 의지, 고객사 요구, 정부지원, 신용평가 반영 모두 ESG 경영 도입의도에 유의한 정(+)의 영향을 미쳤다. 특히 CEO의 의지가 가장 큰 영향을 미치는 것으로 나타났다. 또한 ESG 경영 도입에 미치는 영향 요인과 도입의도와의 관계에서 태도가 매개역할을 하는 것으로 확인되었고, 종업원 혁신저항성의 조절 효과도 있는 것으로 나타났다. 본 연구의 학술적 시사점은 중소기업 ESG와 관련해서 선행연구가 부족한 상황 속에서 ESG 경영 도입 관련 각각의 영향 변수를 도출하고 실증적으로 검정했다는 것이다. 또한 이러한 요인들이 도입의도에 미치는 영향력의 우선순위를 밝혀 ESG 경영 도입 촉진을 방안을 도출했다는 점이다. 실무적 시사점으로는 중소기업의 성공적인 ESG 도입을 위해서는 무엇보다 CEO의 인식개선과 정부지원, 대기업과의 상생 관계가 중요하다는 점이다. 원활한 ESG 경영 도입을 위하여 조직 구성원들과 충분한 소통을 통하여 필요성을 인식하게 함으로써 저항감을 낮출 방안을 모색해야 할 필요도 있었다.