• Title/Summary/Keyword: resistance management

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Comparison between Water and N-Tetradecane as Insulation Materials through Modeling and Simulation of Heat Transfer in Packaging Box for Vaccine Shipping

  • Dao, Van-Duong;Jin, Ik-Kyu;Hur, Ho;Choi, Ho-Suk
    • Clean Technology
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    • v.22 no.1
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    • pp.45-52
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    • 2016
  • This study reports on the modeling and simulation of heat transfer in packaging boxes used for vaccine shipping. Both water and n-tetradecane are used as primary insulation materials inside a multi-slab system. The one-dimensional model, which is a spherical model using a radius equivalent to the rectangular geometry of container, is applied in this study. N-tetradecane with low thermal diffusivity and proper phase transition temperature exhibits higher heat transfer resistance during both heating and cooling processes compared to water. Thus, n-tetradecane is a better candidate as an insulating material for packaging containers for vaccine shipping. Furthermore, the developed method can also become a rapid and economic tool for screening appropriate phase change materials used as insulation materials with suitable properties in logistics applications.

Buckling Probability Evaluation Framework of CWR Tracks (장대레일 궤도의 좌굴확률평가 시스템)

  • Bae, Hyun-Ung;Han, Seung-Ryong;Choi, Jin-Yu;Lim, Nam-Hyoung
    • Proceedings of the KSR Conference
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    • 2010.06a
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    • pp.305-309
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    • 2010
  • The buckling behavior of CWR tracks is affected by the various parameters such as stiffness and geometry of track panel, ballast resistance, rail temperature, initial imperfection, and wheel load. Until now, CWR tracks were managed by the dichotomous logic (deterministic approach) despite these influence factors are having the nature of random variables. So, the design method and existing management process to prevent the track buckling can be very non-economic since the value of these influence factors to calculate the track buckling strength are selected by considering the worst track condition. In this study, buckling probability evaluation process is proposed which is based on the reliability index, AFOSM method, and limit state equation.

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New Fungicides: Opportunities and Challenges - A Case Study with Dimethomorph

  • Spadafora, V. J.;Sieverding, E.
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 1998.06a
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    • pp.50-69
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    • 1998
  • Dimethomorph is a novel fungicide with a high level of activity against diseases induced by certain Oomycetes, including fungal populations that are resistant to other products. In several ways, this fungicide illustrates the opportunities and challenges presented by many modern pesticides. The specific mode of action, which affects cell wall formation, is associated with a very high level of performance and low dose rates under field conditions. These low dose rates, combined with a low level of toxicity to non-target organisms present an outstanding safety profile. This same highly-specific mode of action, however, limits the spectrum of activity and suggests the need for a resistance management plan, both of which must be addressed in new product development. In addition, the biological and physiochemical properties of this, and other new products are not adequately described by the traditional classification of fungicides into“protectant”and“systemic”types. These unique profiles provide novel and useful products for disease control.

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Design of NAND Flash Translation Layer Based on Valid Page Lookup Table (유효 페이지 색인 테이블을 활용한 NAND Flash Translation Layer 설계)

  • 신정환;이인환
    • Proceedings of the IEEK Conference
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    • 2003.11b
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    • pp.15-18
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    • 2003
  • Flash memory becomes more important for its fast access speed, low-power, shock resistance and nonvolatile storage. But its native restrictions that have limited 1ifetime, inability of update in place, different size unit of read/write and erase operations need to managed by FTL(Flash Translation Layer). FTL has to control the wear-leveling, address mapping, bad block management of flash memory. In this paper, we focuses on the fast access to address mapping table and proposed the way of faster valid page search in the flash memory using the VPLT(Valid Page Lookup Table). This method is expected to decrease the frequency of access of flash memory that have an significant effect on performance of read and block-transfer operations. For the validations, we implemented the FTL based on Windows CE platform and obtained an improved result.

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Deleterious Effects of Hyperoxemic Extracorporeal Circulation during Cardiovascular Surgery

  • Park, Seok-Cheol
    • Biomedical Science Letters
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    • v.7 no.1
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    • pp.7-15
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    • 2001
  • Although extracorporeal circulation (ECC) has been routinely used for cardiovascular surgery, hyperoxemia during ECC may produce oxygen toxicity and cellular injury. This study was performed to investigate the clinical influences of hyperoxemic ECC during cardiovascular operation. 40 adult patients scheduled for elective cardiovascular surgery were classified into normoxemic (arterial oxygen tension: 115 mmHg, n=20) and hyperoxemic (arterial oxygen tension: 380 mmHg, n=20) ECC. At preoperative and postoperative period, total leukocyte and neutrophil counts, platelet counts, iron, glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine in peripheral arterial blood, malondialdehyde (MDA) and troponin-T concentration (TnT) in coronary sinus blood, pulmonary vascular resistance (PVR), and postoperative blood loss volume (BLS) were measured and compared between groups. Hyperoxemic group had postoperatively higher total leukocyte and neutrophil counts, MDA, TnT, PVR total BLS, iron, glucose, AST, ALT, BUN, and creatinine than normoxemic group (p<0.05).0 conclusion, hyperoxemic ECC results in greater inflammatory response and oxidative damaging effects on the heart lung, liver and kidney, probably being adverse to postoperative patient recovery. For reducing these deleterious effects and improving postoperative outcomes, management lowering oxygen tension during ECC is recommended.

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Transient heat transfer analysis using Galerkin finite element method for reinforced concrete slab exposed to high elevated temperature

  • Han, Byung-Chan;Kwon, Young-Jin;Lee, Byung-Jae;Kwon, Seung-Jun;Chae, Young-Suk
    • Computers and Concrete
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    • v.18 no.6
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    • pp.1097-1112
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    • 2016
  • Fire loading causes a critical collapse of RC (Reinforced Concrete) Structures since the embedded steels inside are relative week against high elevated temperature. Several numerical frameworks for fire resistance have been proposed, however they have limitations such as unstable convergence and long calculation period. In the work, 2-D nonlinear FE technique is proposed using Galerkin method for RC structures under fire loading. Closed-form element stiffness with a triangular element is adopted and verified with fire test on three RC slabs with different fire loading conditions. Several simulations are also performed considering fire loading conditions, water contents, and cover depth. The proposed numerical technique can handle time-dependent fire loading, convection, radiation, and material properties. The proposed technique can be improved through early-aged concrete behavior like moisture transport which varies with external temperature.

Treatment of Meningitis Caused by Vancomycin-Resistant Enterococcus with Synercid

  • Oh, Hyung-Suk;Jeon, Byung-Chan;Kim, Young-Su;Chun, Tae-Sang
    • Journal of Korean Neurosurgical Society
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    • v.39 no.2
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    • pp.141-143
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    • 2006
  • Vancomycin-resistant enterococci[VRE] are rare cause of meningitis, occurring in immunocompromised patients, severely ill, hospitalized patient, and patients who have undergone neurosurgical procedures. Resistance to vancomycin has increased in frequency during the past few years. Limited therapeutic options are available for VRE infectionsandtheoptimumtherapy has not been established. We report a case of VRE meningitis that was successfully treated with administration of quinupristin-dalfopristin [Synercid] by both intravenous and intraventricular routes. A brief review of the literature is provided, which indicates that optimal management with Synercid should include daily intraventricular doses of at least 2mg and intravenous 0.5mg/kg every 8 hours. We also review the previously reported cases of VRE meningitis.

A Study on the Industrial SWOT Analysis and Benefits for the Successful RFID Implementation (성공적인 RFID 구현을 위한 산업별 SWOT 분석과 성과에 관한 연구)

  • Chang, Yun-Hee
    • The Journal of Information Systems
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    • v.16 no.2
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    • pp.93-122
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    • 2007
  • RFID has fundamental influences on today's business management. This research seeks to formulate the opportunities and challenges, the strengths and weaknesses and the perceived benefits of RFID implementation in three industries: manufacturing, medical-service, and distribution. Ten companies of successful RFID deployment in Korea are presented. Field interview and panel discussion were used to explore the research purpose. The core challenges include RFID readability issues, lack of best practices, increasing prime cost, visible ROI, implementation cost, and employee's resistance. The strengths include IT infrastructure, system integration competency, RFID business model creation ability, executive's support. There is little weakness in Korea companies, there are many perceived benefits in three industries. The most distinctive finding is that the visible ROI was found out in the manufacturing industry, not in the distribution industry. The opportunities and challenges, the strengths and weaknesses and the perceived benefits are some different in three industries, which provide valuable guidance for Korean companies in seeking the RFID opportunities. This case study represents a pioneer research of RFID adoption in Korea.

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A Study on Innovation Resistance and Intention to Use Block chain in Shipping and Port Areas (해운항만분야의 블록체인 도입에 대한 혁신저항과 사용의도에 관한 연구)

  • Kim, Yun-Mi;Chang, Myung-Hee
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2019.11a
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    • pp.189-190
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    • 2019
  • 블록체인의 잠재력이 높은 반면, 아직까지는 현장에서 완전히 검증되지 않은 기술이기 때문에 예상만큼 블록체인의 도입이 이루어 지지 않고 있다. 거래 정보에 대해 제 3의 신뢰기관에서 인증하는 기존의 방식과 달리 블록체인은 네트워크 참여자가 작업증명 등의 방식으로 인증하기 때문에 분산 원장 기술로도 불리는데, 이러한 특성으로 인해 네트워크의 규모가 확대될수록 데이터의 신뢰성 및 투명성이 강화되므로 소비자들의 참여를 촉진하는 것이 ····(중략)····.

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Regulation of Pathogenesis by Light in Cercospora zeae-maydis: An Updated Perspective

  • Kim, Hun;Ridenour, John B.;Dunkle, Larry D.;Bluhm, Burton H.
    • The Plant Pathology Journal
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    • v.27 no.2
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    • pp.103-109
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    • 2011
  • The fungal genus Cercospora is one of the most ubiquitous groups of plant pathogenic fungi, and gray leaf spot caused by C. zeae-maydis is one of the most widespread and damaging foliar diseases of maize in the world. While light has been implicated as a critical environmental regulator of pathogenesis in C. zeae-maydis, the relationship between light and the development of disease is not fully understood. Recent discoveries have provided new insights into how light influences pathogenesis and morphogenesis in C. zeae-maydis, particularly at the molecular level. This review is focused on integrating old and new information to provide an updated perspective of how light influences pathogenesis, and provides a working model to explain some of the underlying molecular mechanisms. Ultimately, a thorough molecular-level understanding of how light regulates pathogenesis will augment efforts to manage gray leaf spot by improving host resistance and disease management strategies.