• The Journal of Industrial Distribution & Business
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• v.13 no.6
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• pp.39-49
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• 2022

Purpose: As part of these efforts, in-depth research is needed on efficient and practical utilization of underground spaces and underground shopping malls. In addition, efforts are being made to find effective alternatives to various problems currently occurring in underground shopping malls, but it is not easy. In addition, the development entity and the maintenance entity are different from each other, and the management is not unified, making it difficult to maintain underground shopping malls. From this point of view, it can be said that it is time to actively and specifically discuss ways to revitalize underground shopping malls. Data and methodology: In the domestic distribution environment, traditional markets and shops are stagnating due to rapid changes in consumption patterns, such as the spread of large companies with advanced distribution techniques such as hypermarkets, shopping malls, and SCM, the rapid increase in Internet and home shopping, and the importance of convenience for young consumers. In order to revitalize underground shopping malls, it is necessary to strengthen the organization and self-rescue efforts of merchants' associations, change consciousness through merchant education, change to specialized markets, find nuclear stores and representative restaurants, and support the hardware sector. Results: The connection of underground shopping malls in each region of the country, where commercial districts are separated from each other, will also play an important role in reviving the function of the city in the future. To do this, it is first necessary to connect underground shopping malls that have been cut off. In other words, connection between connectable underground shopping malls should be promoted. Of course, long-term projects should be promoted step by step, and many consultations should be made on how to connect with the ground for each local government. Conclusion: This is because in the future, the underground space cannot just be a walking place, but another space of the Korean Wave where you can experience satisfying the five senses. K-shopping Hallyu content can be created by creating a characteristic story for each underground shopping mall in the city, permanently this story-oriented event, and creating a safe and elegant environment. If there is a story, so-called "Senomi Shopping" will be possible. A new Korean Wave will be created that can satisfy "the fun of writing, the fun of seeing, and the fun of feeling" at the same time.

• Journal of the Society of Disaster Information
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• v.18 no.1
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• pp.173-181
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• 2022

Purpose: The purpose of this study was to examine the safety awareness and safety behaviors of personal assistant for visual impairments. Method: This study was targeted at 263 personal assistant for blind people from May to June 2021. Research subjects who wished to participate in the study expressed their intention to participate through the recruitment documents and gave written consent before participating in the study. Result: First, the safety awareness and safety behavior were high among the personal assistants who had practical fire extinguisher practice experience and education on how to act in a disaster situation. In addition, when the emergency rescue method was educated, the life safety awareness and fire safety awareness were high, but there was no difference in the awareness of disaster safety, and the safety behavior was higher. Third, the higher the life safety awareness, fire safety awareness, and disaster safety awareness of personal assistant for the visually impaired, the higher the safety behavior. Conclusion: This study revealed that it is important to provide appropriate safety education to personal assistant and implement a program to raise safety awareness so that the visually impaired can live a safer life.

• Tunnel and Underground Space
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• v.32 no.3
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• pp.194-202
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• 2022

An increased number of cases have occurred in applying ICT technology in the resource development field due to factors such as safety, eco-friendliness, and low cost since the 2000s. In Korea, the 2nd mining master plan specified the significance of converging the full cycle of mining and ICT, while the 3rd mining master plan highlighted ICT and smart mining such as supporting the supply of an ICT mining device and introducing demonstrational smart mining. This study introduces the application of an ICT device and safety system operation in the Jangseong underground mine of Korea Cement Co., Ltd. Currently, Jangseong mine combines two different kinds of 3D equipment including the handheld 3D scanner and multi-station that provides both the measurement and 3D scanning to perform a 3D measurement of the mine. Taken from the 3D measurement of the mine, it is now possible to identify any hazardous areas and abnormalities in different directions and analyze the safety of the crown pillar between two stopes in different level. Besides, the real-time location tracking and communications system have established highly efficient rescue and evacuation plans to effectively deal with any accidents in the mine.

• Journal of Korean Neurosurgical Society
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• v.65 no.6
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• pp.790-800
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• 2022

Objective : EID3 (EP300-interacting inhibitor of differentiation) was identified as a novel member of EID family and plays a pivotal role in colorectal cancer development. However, its role in glioma remained elusive. In current study, we identified EID3 as a novel oncogenic molecule in human glioma and is critical for glioma cell survival, proliferation and invasion. Methods : A total of five patients with glioma were recruited in present study and fresh glioma samples were removed from patients. Four weeks old male non-obese diabetic severe combined immune deficiency (NOD/SCID) mice were used as transplant recipient models. The subcutaneous tumor size was calculated and recorded every week with vernier caliper. EID3 and AMP-activated protein kinase α1 (AMPKα1) expression levels were confirmed by real-time polymerase chain reaction and Western blot assays. Colony formation assays were performed to evaluate cell proliferation. Methyl thiazolyl tetrazolium (MTT) assays were performed for cell viability assessment. Trypan blue staining approach was applied for cell death assessment. Cell Apoptosis DNA ELISA Detection Kit was used for apoptosis assessment. Results : EID3 was preferentially expressed in glioma tissues/cells, while undetectable in astrocytes, neuronal cells, or normal brain tissues. EID3 knocking down significantly hindered glioma cell proliferation and invasion, as well as induced reduction of cell viability, apoptosis and cell death. EID3 knocking down also greatly inhibited tumor growth in SCID mice. Knocking down of AMPKα1 could effectively rescue glioma cells from apoptosis and cell death caused by EID3 absence, indicating that AMPKα1 acted as a key downstream regulator of EID3 and mediated suppression effects caused by EID3 knocking down inhibition. These findings were confirmed in glioma cells generated patient-derived xenograft models. AMPKα1 protein levels were affected by MG132 treatment in glioma, which suggested EID3 might down regulate AMPKα1 through protein degradation. Conclusion : Collectively, our study demonstrated that EID3 promoted glioma cell proliferation and survival by inhibiting AMPKα1 expression. Targeting EID3 might represent a promising strategy for treating glioma.

• Journal of the Korea Society of Computer and Information
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• v.27 no.5
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• pp.1-9
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• 2022

Localization systems can be used with various circumstances like measuring population movement and rescue technology, even in security technology (like infiltration detection system). Vision sensors such as camera often used for localization is susceptible with light and temperature, and can cause invasion of privacy. In this paper, we used ultra-wideband radar technology (which is not limited by aforementioned problems) and machine learning techniques to measure the number and location of occupants in other indoor spaces behind the wall. We used four different algorithms and compared their results, including extremely randomized tree for four different situations; detect the number of occupants in a classroom, split the classroom into 28 locations and check the position of occupant, select one out of the 28 locations, divide it into 16 fine-grained locations, and check the position of occupant, and checking the positions of two occupants (existing in different locations). Overall, four algorithms showed good results and we verified that detecting the number and location of occupants are possible with high accuracy using machine learning. Also we have considered the possibility of service expansion using the oneM2M standard platform and expect to develop more service and products if this technology is used in various fields.

• Science of Emotion and Sensibility
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• v.24 no.2
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• pp.25-38
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• 2021

The aim of this study is to protect workers and pedestrians from accidents at night or bad weather by attaching optical fiber to existing safety clothing that is made only with fluorescent fabrics and retroreflective materials. A safety vest was designed and manufactured by applying optical fiber, and energy-harvesting technology was developed. The safety vest was designed to emit light using the automatic flashing of optical fibers attached to the film, and an energy harvester was manufactured and attached to drive the light emission of the optical fiber more continuously. As a result, first, the vest wearer' body was recognized from a distance through the optical fiber and retroreflection, which helped prevent accidents. Thus, this concept helps in saving lives by preventing accidents during night-time work on the roadside or activities of rescue crew and sports activities, or by quickly finding the point of an accident with a signal that changes the optical fiber light emission. Second, to use the wasted energy, a piezoelectric-element power generation system was developed and the piezoelectric-harvesting device was mounted. Potentially, energy was efficiently produced by activating the effective charging amount of the battery part and charging it auxiliary. In the existing safety vest, detecting the person wearing the vest is almost impossible in the absence of ambient light. However, in this study, the wearer could be found within 100 m by the light emission from the safety vest even with no ambient light. Therefore, in this study, we will help in preventing and reducing accidents by developing smart safety clothing using optical fiber and energy harvester attached to save lives.

• The Journal of the Korea Contents Association
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• v.21 no.7
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• pp.281-290
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• 2021

The scope of fire services has been expanded from local fire prevention to rescue and first aid services, and the fire services system has been converted from an autonomous fire services system to a wide-area fire services system, and the status of fire officers has been unified as a national public servant. However, the underlying problem remains unsolved. One is a problem related to the conversion of fire services to state affairs, and the other is that Fire officers converted to national public servants are in charge of fire services which are evaluated as local autonomous affairs. The controversy over the nature of fire service stems from uncertainty and redundancy in the coordination of office function and distribution between the State and Local governments, and incomplete legislation that fundamentally fails to achieve systematic unity of office work and status. The fire service has a national responsibility as an affair that includes the existence of the state and the welfare and order of the people along with the police affairs. That is, affairs related to the safety of the people that protect the lives, bodies and properties of the people should be understood as State affairs. 「The LOCAL AUTONOMY ACT」 stipulates that local governments cannot perform State affairs such as affairs necessary for the existence of the nation, affairs requiring performance in a uniform manner throughout the nation, and affairs of nationwide or similar scale unless otherwise provided by the law. Fire Service should be regarded as such affairs. Considering that the rights to the safety and life of the people and the duty to protect the people are the duty of the nation, it is necessary to keep in mind that the reason for the change fire officers to the national public servants was not basically just a matter of treatment and finance.

• Journal of Korea Entertainment Industry Association
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• v.14 no.7
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• pp.477-485
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• 2020

This study is a random allocation similar experimental study to compare and analyze the difference in BVM (Bag-Valve-Mask) ventilation volume according to the characteristics of the rescuer's hand and the type of mask using a standardized mannequin. To this end, the Basic Life Resuscitation Education Center of D University in gwangju. Recruiting 39 students who have completed the basic resuscitation course for emergency medical personnel and the Korean-style specialized cardiac rescue course, In addition to measuring the physical characteristics of the hand, the average amount of ventilation per minute using a bag-mask was measured and analyzed. As a result, the type of mask that was not most affected by the characteristics of the hand and provided adequate Minute Ventilation was the soft type (tube, silicone) mask. On the other hard (tube, silicone) masks were found to be unsuitable for general use as they were greatly affected by the characteristics of workers' hands. COVID-19 is currently increasing the risk of transmission to paramedics and patients. Considering this situation, the universal use of a semi-permanent hard-type mask, which is disadvantageous not only for preventing infection but also for proper ventilation, should be avoided. In addition to the ease of use, it should be actively utilized in the field by supplying a soft type mask that can provide stable ventilation even with 'predominance recognition' and proper ventilation.

• Journal of the Korea Convergence Society
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• v.13 no.2
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• pp.257-262
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• 2022

The purpose of this study was to examine the inhibition of human cancer cell proliferation by using various concentrations of Beet Extract containing various bioactive ingredients. The six cancer cell lines used in the experiment were prostate cancer cells DU-145, lung cancer cells A549, breast cancer cells MCF-7, cervical cancer cells HeLa, liver cancer cells SNU-182, and biliary tract cancer cells SNU-1196. Human-derived cancer cell lines were used. The inhibition of cancer cell proliferation at various concentrations of Beet Extract was measured by the CCK-8 method. As a result of examining the inhibition of cancer cell proliferation, Beet Extract significantly and concentration-dependently inhibited DU145 of prostate cancer cells at all concentrations, and Lung cancer cells A549 and DU-145 of prostate cancer cells at 100ug/mL and 1000ug/mL, cervical cancer cells HeLa, and liver cancer cells SNU- 182, biliary tract cancer cell SNU-1196 showed significant proliferation inhibition at 1000ug/mL. Experiment result, the cancer cell proliferation inhibitory mechanisms of Beet Extract using various human-derived cancer cell lines can be considered to provide cancer prevention effects and the possibility of developing functional foods.

• Journal of Pharmacopuncture
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• v.25 no.3
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• pp.233-241
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• 2022

Objectives: Asthma is a chronic disease, and the demand for herbal medicines in this field has increased in recent years. The new findings highlight the role of the gut-lung axis in the pathophysiology of asthma. Hence, this study will evaluate the safety and efficacy of Glasthma syrup, an herbal formula based on Persian medicine, in improving asthma and regulating intestinal permeability. The formula consists of five herbal ingredients that have anti-inflammatory effects on the respiratory tract, also known as gut tonics. Methods: The study will be conducted as a placebo-controlled, triple-blind, randomized trial. It will consist of a 4-week intervention followed by a 4-week follow-up period. The target sample size is 20 patients with moderate asthma aged 18 to 60 years. Eligible participants will be randomly assigned to either the experimental group or the control group in equal numbers. Patients in the experimental group will take Glasthma syrup (7.5 mL, twice a day), while patients in the control group will take a matching placebo. Both groups will receive a 4-week combination of a long-acting beta2 agonist and a leukotriene modulator as standard of care. Inhaled corticosteroids can be used as rescue medication as needed. Results: The primary outcomes are asthma symptom scale, lung function, and intestinal permeability. Secondary outcomes include quality of life, symptom recurrence rates, and blood tests. A safety assessment will also be conducted during the trial. Conclusion: In this trial, the effects of Glasthma syrup in patients with moderate asthma will be examined. The study will also assess the effects of the formulation on the gut-lung axis by simultaneously monitoring the gut permeability index, asthma symptoms, and lung function.