• Journal of the Korea Institute of Building Construction
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• v.13 no.3
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• pp.282-290
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• 2013

In this study, the adjustment range of mixture factor with replacement mineral admixture was reviewed to secure the mixture change data of high volume concrete compared to general concrete. When changing the concrete mix to high volume concrete within the universal concrete mixing, the adjustment range of mixture to ensure optimum quality is as follows. Unit-water content is $20{\sim}30kg/m^3$ downward. Fine aggregate ratio dropped by approximately 1% when W/B was reduced by 5%, and it is reduced by approximately 0.12% when there is a 5% increase in the total replacement rate. When the FA replacement rate was increased by 5%, the AE agent was approximately 20% to 30% higher compared with the conventional one. When the FA and BS replacement rate rose by 5%, W/B was reduced by about 1 to 4%.

• Journal of Sensor Science and Technology
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• v.30 no.2
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• pp.109-113
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• 2021

In this study, an automated culture media replacement system was developed to analyze changes in the contraction characteristics of cardiomyocytes according to the state of the culture media. For the long-term storage of culture media, a Peltier refrigerator with a temperature of 5 to 8℃ was provided and a pH of 7.4 was maintained. The cell culture media of the cardiomyocytes was continuously replaced using interlocking pumps at a flow rate of 0.83 μl/h. The cardiomyocytes in which the culture media was replaced automatically demonstrated lower heartbeats per minute compared to samples in which there was no replacement. However, these cardiomyocytes moved more uniformly and produced greater displacement in one heartbeat cycle. It was observed that the sarcomere length of the cardiomyocytes increased due to the automated culture media replacement system. These cardiomyocytes were found to demonstrate better maturation compared to the control group. The maturation of cardiomyocytes was verified through staining images. The proposed automated culture media replacement system generates a uniform heart rate and improvements in contraction force. Based on the study, patient-specific drug toxicity assessments can be conducted using differentiated cardiomyocytes in induced pluripotent stem cells.

• Particle and aerosol research
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• v.20 no.2
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• pp.69-77
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• 2024

In this study, the performance of air cleaners installed in subway stations was evaluated using field test method and chamber test method in accordance with the standard for air cleaner. Also, the air filter maintenance period was examined by the performance reduction of air cleaners with respect to the air filter usage period. From the field tests, the clean air delivery rate (CADR) of air cleaners with filter in use was about 85% on average compared to the ones with new filter. The main factor of CADR reduction was not the decrease of filter efficiency but the decrease of airflow rate. The chamber test results shows that the CADR of air cleaners decreased with the usage time, but the proper filter replacement can make the CADR keep about 95% of the certified CADR. The expected filter replacement cycle measured by the field test method was calculated to be approximately 3.35 months (100 days). However, the replacement cycle was a large difference between 1.2 and 6.6 months with the different stations. Therefore, the replacement cycle should be individually investigated for each station. The use of air cleaners must be effective in reducing fine dust in subway stations. For more effective air quality management in subway stations, additional researches is necessary to define the appropriate capacity of HVAC system and air cleaner, and related maintenance for each station.

• Journal of Korean Society for Quality Management
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• v.32 no.3
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• pp.62-67
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• 2004

This paper presents and compares two block replacement policies under random use durations. The units are put in service altogether and then idle for some time. The time durations during which units are put in service are random variables. Two block replacement policies, called N-policy and T-policy, are presented. Under N-policy, units are replaced altogether after the Nth use. Under T-policy, units are replaced altogether at the end of the use after cumulative use time T elapses. The failures during use durations are replaced by new ones individually. The cost rate expressions under the policies are derived for exponential use durations. Numerical examples are presented to compare the performances of the two policies.

• Journal of Korean Society for Quality Management
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• v.40 no.1
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• pp.88-91
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• 2012

Joint optimization of preventive age replacement and inventory policy is considered in this paper. There are three decision variables in the problem: (i) preventive replacement age of the operating unit, (ii) order quantity per order and (iii) reorder point for spare replenishment. Preventive replacement age and order quantity are jointly determined so as to minimize the expected cost rate, and then the reorder point for meeting a desired service level is found. A numerical example is included to explain the joint optimization model.

• Journal of the military operations research society of Korea
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• v.17 no.1
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• pp.1-24
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• 1991

This report concerns the study of deciding replacement requirements for 1/4ton truck in Korea. Two causes of replacement, accidental loss and wearout are considered in the replacement requirements model which was developed in Defence Logistics Agency. The model represents the state of 1/4 ton truck inventory over time as a finite Markov chain process. An accidental loss rate, yearly usage rates. wearout rates are used in conjuction with the current mileage distribution of the inventory to forecast replacement requirements in future time periods.

• ETRI Journal
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• v.6 no.3
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• pp.17-20
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• 1984

A block replacement policy using items with different reliability is discussed. We devide system unit failure modes into two modes and use less reliable unit when operating unit fails near the planned preventive replacement time. In this policy, item A has two failure modes. Mode-1 failure is removed by minimal repair, mode-2 failure by replacement. If mode-2 failure of item A happens in (0,T- $\delta$). failure item A is replaced by new item A. If mode-2 failure of item A happens in(T-$\delta$,T), failure item A is replaced by new item B. Item B should be cheaper and less durable than item A. Under this policy, we determine the preventive replacement interval T and the interval $\delta$ of item B replacement which minimize the cost rate per unit time.

• Communications for Statistical Applications and Methods
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• v.9 no.1
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• pp.21-31
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• 2002

This paper considers a Bayesian approach to determine an optimal replacement policy for a repairable system with warranty period. The mathematical formula of the expected cost rate per unit time is obtained for two cases : RFRW(renewing free-replacement warranty) and RPRW(renewing pro-rata warranty). When the failure time is Weibull distribution with uncertain parameters, a Bayesian approach is established to formally express and update the uncertain parameters for determining an optimal replacement policy. Some numerical examples are presented for illustrative purpose.

• Journal of the Korean Data and Information Science Society
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• v.17 no.3
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• pp.743-752
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• 2006

This paper considers a Bayesian approach to replacement policy model with minimal repair. We use the criterion based on the expected cost and the expected downtime to determine the optimal replacement period. To do so, we obtain the expected cost rate per unit time and the expected downtime per unit time, respectively. When the failure time is Weibull distribution with uncertain parameters, a Bayesian approach is established to formally express and update the uncertain parameters for determining an optimal maintenance policy. Especially, the overall value function suggested by Jiagn and Ji(2002) is applied to obtain the optimal replacement period. The numerical examples are presented for illustrative purpose.

• Journal of Chest Surgery
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• v.22 no.3
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• pp.393-401
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• 1989

Between Dec. 1984, and May, 1988,96 prostheses were implanted in 80 patients at Dept. of Thoracic k Cardiovascular Surgery of National Medical Center. 43 patients had mitral valve replacement, 21 underwent aortic valve replacement, and 15 had double valve replacement [Mitral k Aortic], and 1 had tricuspid valve replacement. Seventy-one cases [88.8 %] were in NYHA Class III or IV. The mean duration of follow up was 22.1 months and follow-up information was available for 74 [92.5 %] of the patients. The overall actuarial survival rate at 45 months was 93.05 % and overall hospital mortality was 10 %, late Mortality was 5 %. The linearlized incidence of thromboembolism [2.4%/pt-yr], thrombotic valve obstruction [1.6 %/pt-yr], anticoagulant related bleeding [0.8 %/pt-yr]. There were no fatal valve related complications. The blood was studied in 40 patients 1 year after valve operation. Hgb and reticulocyte count were within normal values and Serum LDH value was slightly elevated but it was not of clinical significance. In conclusion, Monostrut Bjork-Shiley valve prosthesis to be a reliable valve substitute with an acceptable incidence of complications.