• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5275-5279
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• 2013

Background: The XRCC1 (X-ray repair cross complimenting group-I) gene in BER (base excision repair) pathway is essential for DNA repair process. Polymorphisms in this gene are associated with variations in the repair efficiency which might predispose individuals to development of various cancers. Two variants of XRCC1gene (at codon 399), Gln/Gln and Arg/Gln, have been shown to be related to lowered DNA repair capacity and increased genomic instability in multiple studies. Hence our investigation focused on genotyping these variants to correlate with other multiple risk factors in lung cancer (NSCLC) patients since we hypothesized that these variants of the XRCC1 gene might influence disease susceptibility. Materials and Methods: We examined the frequency of the polymorphism in one hundred cases and an almost equal number of controls after recording their demographics with a structured questionnaire. Genomic DNA from blood samples was extracted for PCR studies, followed by RFLP to determine the variants. The significance of the data was statistically analyzed. Results: The three genotypes in cases and controls were Arg/Arg (40% and 54.45%); Gln/Gln (19% and 9.90%), and Arg/Gln (41.0% and 35.64%) respectively. Among these 3 genotypes, we found Gln/Gln and Arg/Gln to show association with lung cancer. Correlating these genotypes with several parameters, we also found that these two variants were associated with risk in males (p<0.05) and with smoking habits (p<0.05). In females Arg/Gln genotype showed association with stage of the disease (p=0.04). This is the first report in South Indian scenario where Arg399Gln genotypes were found to be associated with stage of the disease in females. Conclusions: It is concluded that XRCC1 genotypes Gln/Gln and Arg/Gln may influence cancer susceptibility in patients with smoking habits and these functional SNPs in XRCC1 gene may act as attractive candidate biomarkers in lung cancer for diagnosis and prognosis.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 학회창립 10주년 기념 1999년도 가을 학술발표회 논문집
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• pp.545-548
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• 1999

The purpose of this study is application of strengthening technique of R/C concrete bridge by standardization of repair and rehabilitation. For that, experiment to bridge is necessary, and through the experiment, this study can identify the efficiency o applied method and analysis of design parameters with can't get in the laboratory experiment. This study will prove the structural behavior of R/C type girder bridge which is deteriorated but repaired and rehabilitation from standardized strengthening method with fiber plastic.

• 대한전기학회논문지:전력기술부문A
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• 제55권2호
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• pp.70-75
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• 2006

Owing to the strike of lightning a breakage of insulator would happen. This breakage may give rise to many problems such as increment of reclosing failure, a drop for reliance and a hardship of maintenance and repair. To solve those problem, this study develop a protected equipment for insulator which is suitable to 22.9[kV] distribution line towers and is purposed to investigation for a Proper adaption, Protection efficiency of insulator and effect of adaption.

• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2006년도 추계학술발표논문집
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• pp.172-175
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• 2006

Owing to the strike of lighting a breakage of insulator would happen. This breakage may give rise to many problems such as increment of reclosing failure, a drop for reliance and a hardship of maintenance and repair. To solve those problems, this study develop a protected equipment for insulator which is suitable to 22.9kV distribution line towers and is purposed to investigation for a proper adaption, protection efficiency of insulator and effect of adaption.

• 산업경영시스템학회지
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• 제21권48호
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• pp.279-289
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• 1998

This study deals with the schemes of design, plan and operate maintenance management support systems and with the engineering approach for the solutions to build the maintenance management for the production efficiency. Maintenance Management Information System(MMIS) is the task that must focus on machinery historical data and planned maintenance action. Also the efficient supporting system in a maintenance management is achieved by database which is based on process of machinery's failure history. Designing method of maintenance management information system, maintenance modules are consisted of six factors ; machinery's historical data, lubrication control, check sheet, repair work, availability report, and performance report(control board and detailed reports), and then operators can rapidly utilize data in work place. In the implementation of designed model, program coding has been developed by Visual Basic 3.0. Data insertion, deletion and updating which perform menu screen is implemented by reading data from database. Implementation model based on LAN environment and related data is stored in Microsoft DBMS.

• 안보군사학연구
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• 통권13호
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• pp.659-685
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• 2016

At this research, author discusses about ROK Army military supplies distribution system and suggests a direction of development as follows in order to achieve maximum efficiency. First, Develope a scientific technique to estimate quantity of repair part for futher demanding at the budgetting and procurement planning stage. Second, Introduce an Logistic Revolving Fund in other to reduce the procurement lead time & assure flexible procurement all year round. Third, Reestabilish supply step stages and reduce stock level which is authorized stock amount in logistic support unit. Fourth, Estabilish civilian - military integrated military supplies distribution system to improve the efficiency of logistics.

• 건설안전기술
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• 통권52호
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• pp.58-66
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• 2011

This study presents an algorithm to select the best alternative plane among various bridge superstructure types (Steel box girder, Rational girder, PSC-I girder) using Value Engineering (VE). Economical efficiency, landscape, constructability, maintenance, stability, function of bridge superstructure were taken into consideration in the designing of bridge. Economical efficiency was evaluated for each alternative plan with optimal design considering Life Cycle Cost (LCC), Repair and rehabilitation histories and some factors were set to get reasonable results. In the application of Analytic Hierarchy Process (AHP), consistency of Pairwise Comparisons Matrix was evaluated and the best plan was determined.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 추계학술대회 논문집 전기기기 및 에너지변환시스템부문
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• pp.304-308
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• 2002

This paper studies stand-alone photovoltaic array for solar lighting lamp. The solar lighting lamp has PV modules, batteries. and charge & discharge system. The charge efficiency is improved for the control of each battery which is divided the charge from the discharge to change the structure of existing solar lighting lamp charge & discharge system. so, the charge and discharge times are reduced of 50%. and the depth of discharge control can be controlled in the discharge cut off voltage. This can be effective of battery use. If a battery is out of order, this system can be executed for a regular period. so we saved the repair cost and developed of system's stabilization. It is possible economical effect to apply for solar lighting lamp used photovoltaic array.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2009년도 춘계학술대회 논문집
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• pp.1989-1992
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• 2009

Maintenance is classified preventive maintenance before performing equipment failure and corrective maintenance after performing equipment failure. In preventive maintenance, we may analyze the failure data to end from beginning of equipment and allocate maintenance method and calculate maintenance cycle quantitatively by the failure data analysis. So, it has a merit to reduce system maintenance cost and to operate effectively but, it require high cost in system introducing and continuous operation to end of system. In corrective maintenance, we may calculate MTTR(mean time to repair) quantitatively based on function failure time. it can be based on establishing maintenance system for operation efficiency. In this paper, we may reflect the MTTR for the onboard equipped in Tilting train to establish maintenance system for Tilting train operation efficiency.

• 한국안전학회지
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• 제24권6호
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• pp.79-85
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• 2009

This study presents an algorithm to select the best alternative plane among various bridge superstructure types(Steel box girder, Rational girder, PSC-I girder) using Value Engineering(VE). Economical efficiency, landscape, constructability, maintenance, stability, function of bridge superstructure were taken into consideration in the designing of bridge. Economical efficiency was evaluated for each alternative plan with optimal design considering Life Cycle Cost(LCC). Repair and rehabilitation histories and some factors were set to get reasonable results. In the application of Analytic Hierarchy Process(AHP), consistency of Pairwise Comparisons Matrix was evaluated and the best plan was determined.