• 제목/요약/키워드: reduced sample size

검색결과 150건 처리시간 0.038초

사물탕가미방이 백서의 좌우 중대뇌 동맥 폐쇄에 의한 뇌허혈 손상의 회복에 미치는 효과 (Effects of Samul-tang-gamibang against Focal Cerebral Ischemic Damage by Middle Cerebral Artery Occulusion of Rats)

  • 서창훈;김영균;권정남
    • 대한한의학회지
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    • 제25권1호
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    • pp.117-128
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    • 2004
  • Objectives : This research was performed to investigate effect of Samul-tang-gamibang against focal cerebral ischemic damage after middle cerebral artery occlusion(MCAO). Methods : This research was used rats which were against focal cerebral ischemic damage by MCAO. It was used Zea Longa's theory and Belayev's methods to give rise to focal cerebral ischemic damage by MCAO. After 7days later, we drew out the brain and then had frozen and dyeing it and we had taken a picture to measure of the damaged area in each brain section. We determined the Neurological Index and tested the Foot-fault test and Roatated test to appraise the fall of motion ability result from cerebral ischemic damage. Results : The results of the experiment are as follows. 1. Samul-tang-gamibang reduced infarct size of sample group compared to control group at 7 day after MCAO. 2. Samul-tang-gamibang reduced infarct volume of sample group compared to control group at 7 day after MCAO. 3. Samul-tang-gamibang reduced foot-fault index of sample group compared to control group at 5,7 day after MCAO. Conclusions : Samul-tang-gamibang has protective effects against ischemic brain damage and had significant reduced infarct size and infarct volume of Rt-MCAO.

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Effects of the Pore Size of Graphite on the Mechanical Properties and Permeability of a Porous Nozzle for Continuous Casting Process

  • Cho, Yong-Ho;Kim, Juyoung;Yoon, Sanghyeon;Lee, Heesoo
    • 대한금속재료학회지
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    • 제49권7호
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    • pp.530-534
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    • 2011
  • To analyze the effect of the pore size of graphite in a pore-forming agent, graphite was added to porous ceramics of $Al_2O_3-SiO_2-ZrO_2$ systems. The graphite had 45~75, 100~125, 150~180, and 75~180${\mu}m$ dimensions. The properties of the ceramics, such as apparent porosity, density, dynamic elastic modulus, mechanical strength, and permeability, were investigated. The average pore size increased from 15.35${\mu}m$ to 22.32${\mu}m$ with the increase of the graphite size. The sample with the largest average pore size showed the highest mechanical strength and gas permeability. This was due to the sample with the largest pore size at the same porosity having fewer pores and larger distance between the pores than the sample with the smallest pore size, making cracks less likely to propagate. In addition, the large pore size reduced the repulsive power originating from the drag force between the gas and internal pore walls.

추백리-가금티푸스의 혈청학적 모니터링 계획수립을 위한 표본크기 (Determination of sample size to serological surveillance plan for pullorum disease and fowl typhoid)

  • 박선일;박최규
    • 대한수의학회지
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    • 제48권4호
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    • pp.457-462
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    • 2008
  • The objective of this study was to determine appropriate sample size that simulated different assumptions for diagnostic test characteristics and true prevalences when designing serological surveillance plan for pullorum disease and fowl typhoid in domestic poultry production. The number of flocks and total number of chickens to be sampled was obtained to provide 95% confidence of detecting at least one infected flock, taking imperfect diagnostic tests into account. Due to lack of reliable data, within infected flock prevalence (WFP) was assumed to follow minimum 1%, most likely 5% and maximum 9% and true flock prevalence of 0.1%, 0.5% and 1% in order. Sensitivity were modeled using the Pert distribution: minimum 75%, most likely 80% and maximum 90% for plate agglutination test and 80%, 85%, and 90% for ELISA test. Similarly, the specificity was modeled 85%, 90%, 95% for plate agglutination test and 90%, 95%, 99% for ELISA test. In accordance with the current regulation, flock-level test characteristics calculated assuming that 30 samples are taken from per flock. The model showed that the current 112,000 annual number of testing plan which is based on random selection of flocks is far beyond the sample size estimated in this study. The sample size was further reduced with increased sensitivity and specificity of the test and decreased WFP. The effect of increasing samples per flock on total sample size to be sampled and optimal combination of sensitivity and specificity of the test for the purpose of the surveillance is discussed regarding cost.

Design of an Ultra-Compact UHF Passive RFID Tag Antenna for a Medical Sample Tube

  • Lee, Jung-Nam;Hwang, Moon-Young;Lee, Sang-Il;Lee, Kwang-Chun;Park, Jong-Kweon
    • ETRI Journal
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    • 제34권6호
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    • pp.974-977
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    • 2012
  • In this letter, a small-sized ultra-high frequency (UHF) RFID tag antenna for a medical sample tube is proposed. The RFID tag antenna is designed and fabricated based on the circular loop antenna used in the UHF band (Korea standard, 917 MHz to 923.5 MHz). The tag antenna size is reduced using a circular meander stub. The antenna has a physical size of 8 mm, which is about ${\lambda}$/40 in electrical length. The proposed tag antenna is molded into a medical sample and multitag identification is performed.

구조-음향 연성해석을 통한 모형차실 모델의 소음저감 기술연구 (Noise reduction of a vehicle acoustic cavity sample using coupled Structural-Acoustic element analysis)

  • 김태정;강성종;서정범
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 1994년도 추계학술대회논문집; 한국종합전시장, 18 Nov. 1994
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    • pp.288-294
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    • 1994
  • A study of prediction and qualification techniques for structure borne booming noise is presented in this paper. Result from acoustic normal mode finite element analysis of a 1/2 size vehicle cavity sample model is compared to the that from an experiment. Coupled structural-acoustic analysis is performed on a 1/4 size vehicle cavity sample model surrounded by 2 mm thick normal steel plates. Interior noise levels around passensger's ear position are predicted and reduced by structural modification based on panel participation factor analysis about the sample cavity model. Futhermore, optimization technique in application of anti-vibration pad is studied.

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Reduction in Sample Size Using Topological Information for Monte Carlo Localization

  • Yang, Ju-Ho;Song, Jae-Bok;Chung, Woo-Jin
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2005년도 ICCAS
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    • pp.901-905
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    • 2005
  • Monte Carlo localization is known to be one of the most reliable methods for pose estimation of a mobile robot. Much research has been done to improve performance of MCL so far. Although MCL is capable of estimating the robot pose even for a completely unknown initial pose in the known environment, it takes considerable time to give an initial estimate because the number of random samples is usually very large especially for a large-scale environment. For practical implementation of the MCL, therefore, a reduction in sample size is desirable. This paper presents a novel approach to reducing the number of samples used in the particle filter for efficient implementation of MCL. To this end, the topological information generated off- line using a thinning method, which is commonly used in image processing, is employed. The topological map is first created from the given grid map for the environment. The robot scans the local environment using a laser rangefinder and generates a local topological map. The robot then navigates only on this local topological edge, which is likely to be the same as the one obtained off- line from the given grid map. Random samples are drawn near the off-line topological edge instead of being taken with uniform distribution, since the robot traverses along the edge. In this way, the sample size required for MCL can be drastically reduced, thus leading to reduced initial operation time. Experimental results using the proposed method show that the number of samples can be reduced considerably, and the time required for robot pose estimation can also be substantially decreased.

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적합탐색 관찰을 이용한 층화 공간표본설계에서의 추정 (Adaptive Searching Estimation in Stratified Spatial Sample design)

  • 변종석
    • 응용통계연구
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    • 제13권2호
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    • pp.353-369
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    • 2000
  • 관찰 단위들간 특정한 공간 종속관계를 지닌 공간모집단에서 사각형의 칸들로 분할한 후 각 칸마다 하나의 표본점을 임의추출하여 관심 변수의 모수를 추정할 때 탐색 관찰조건을 만족하는 인접한 표본단위만을 추가 관찰하여 모수를 추정하는 적합탐색 추정 방법을 층화 공간표본설계에 적용시켜 보았다. 모의자료를 설정한 가상의 2차원 공간모집단을 층화 공간표본설계에 의해 층화시킨 후 적합 탐색 추정방법을 적용시켜 본 결과, 단순히 공간모집단을 분할하는 전통적인 공간표본설계보다 적은 수의 표본이 관찰되었으며, 효율성이 크게 감소하지 않는 결과를 얻음으로써 층화효과와 적합탐색 관찰효과가 동시에 존재하는 적절한 추정 결과를 얻을 수 있었다.

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소지역 추정방법을 이용한 실업자 수 추정 사례연구 (Estimation of the Number of the Unemployed Using Small Area Estimation Methods)

  • 권세혁
    • 한국조사연구학회지:조사연구
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    • 제10권1호
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    • pp.141-154
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    • 2009
  • 정보화 사회에서는 목표지향적이고 세분화된 통계의 필요성이 높아지고 있으나 현재 사용되는 조사체계를 이용하면 추정 분산이 커져 생산된 통계의 정확도가 낮아진다. 표본크기를 늘리면 추정분산을 줄일 수 있으나 비용이나 시간 면에서는 비효율적이다. 현재와 비슷한 규모의 표본조사구 조사와 일반 행정통계를 이용하여 일정 신뢰수준을 갖춘 통계를 생산할 수 있는 소지역 추정법에 대한 연구가 진행되어 개발 적용되고 있다. 본 연구에서는 소지역 추정법을 활용하여 대전광역시의 5개 구별 실업자 수를 추정하고 추정치의 CV 값을 계산하여 추정방법의 효율성을 비교하는 사례분석을 실시하였다. 또한 합성추정량과 복합추정량의 MSE를 보다 정확하게 계산하는 방법으로 잭나이프 방법을 제안하고 계산방법을 보였다.

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OBSERVATION OF THE SWEATING IN LIPSTICK BY SCANNING ELECTION MICROSCOPY

  • Seo, Su-Youn;Lee, In-Sook;Sin, Hyeon-Jong;Choi, Kyu-Yeol;Kang, She-Hoon;Ahn, Ho-Jeong
    • 대한화장품학회지
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    • 제22권2호
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    • pp.182-192
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    • 1996
  • In this study, the relationship between wax matrix in lipstick and sweating was investigated by observing the change of size and shape of wax matrix with sweating by Scanning Electron Microscopy (SEM). For observation by SEM, a lipstick sample was frozen in liquid nitrogen, then the oil in the lipstick was extracted out in cold isopropanol($-70^{\circ}C$) for 1-3days. After isopropanol was evaporated, the sample was sputtered with gold, and examined by SEM. When examined the sweated sample by SEM, the change of wax matrix underneath the surface from fine, uniform structure to coarse, nonuniform structure was observed, which was resulted from the caking of surrounding wax matrix. That is, the oil underneath the surface was migrated to the surface of lipstick with sweating, consequently the wax matrix at that region was rearranged into the coarse matrix. In case of flamed lipstick, sweating was delayed and the wax matrix was much coarser than that of unflamed one. Its larger wax matrix at surface region was good for including oil. The effect of molding temperature on sweating was also studied. As the molding temperature was increased, sweating was greatly reduced and the size of wax matrix was increased. It was also found that sweating was influenced with the compatinility of wax and oil. A formula consisting of wax and oil which have good compatibility has a tendency of reduced sweating and increased size of wax matrix. When pigment was added to wax and oil. It was also found that sweating was influenced with the passage of time by observing a thick membrane of wax on surface of lipstick after a month from molding. In case of some lipsticks, the size of wax matrix was altered to bigger or smaller. In conclusion, the structure of wax matrix at the surface region of lipstick was changed with the process of foaming, molding temperature, compatibility of wax and oil, addition of pigment, and the passage of time. In most cases, as the size of wax matrix was increased, sweating was reduced and delayed.

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구제역 관리를 위한 혈청학적 예찰계획 평가 (Evaluation of Serological Surveillance System for Improving Foot-and-Mouth Disease Control)

  • 박선일;신연경
    • 한국임상수의학회지
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    • 제30권4호
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    • pp.258-263
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    • 2013
  • The primary goal of this study was to compute sample sizes required to achieve the each aim of a variety of foot-and-mouth disease (FMD) surveillance programs, using a statistically valid technique that takes the following factors into account: sensitivity (Se) and specificity (Sp) of diagnostic test system, desired minimum detectable prevalence, precision, population size, and desired power of the survey. In addition, sample sizes to detect FMD if the disease is present and also as proof of freedom were computed. The current FMD active surveillance programs consist of clinical, virological, and serological surveillance. For the 2012 serological surveillance, annual sample sizes (n = 265,065) are planned at four separate levels: statistical (n = 60,884) and targeted (n = 115,232) at breeding pig farms and slaughter house, in together with the detection of structural proteins (SP) antibodies against FMD (n = 88,949). Overall, the sample size was not designed taking the specific aims of each surveillance stream into account. The sample sizes for statistical surveillance, assuming stratified two-stage sampling technique, was based to detect at least one FMD-infected case in the general population. The resulting sample size can be used to obtain evidence of freedom from FMD infection, not for detecting animals that have antibodies against FMD virus non-structural proteins (NSP). Additionally, sample sizes for targeted surveillance were not aimed for the population at risk, and also without consideration of statistical point of view. To at least the author's knowledge, sampling plan for targeted, breeding pig farms and slaughter house is not necessary and need to be included in the part of statistical surveillance. Assuming design prevalence of 10% in an infinite population, a total of 29 animals are required to detect at least one positive with probability of 95%, using perfect diagnostic test system (Se = Sp = 100%). A total of 57,211 animals needed to be sampled to give 95% confidence of estimating SP prevalence of 80% at the individual animal-level with a precision of ${\pm}5%$, assuming 800 herds with an average 200 heads per farm, within-farm variance of 0.2, between-farm variance of 0.05, cost ratio of 100:1 of farm against animals. Furthermore, 779,736 animals were required to demonstrate FMD freedom, and the sample size can further be reduced depending on the parameters assumed.