• Title/Summary/Keyword: recovery cost

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Comparison of the Surgical Approaches for Frontal Traumatic Intracerebral Hemorrhage

  • Park, Eun Sung;Moon, Seong Keun;Eom, Ki Seong
    • Journal of Trauma and Injury
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    • v.32 no.2
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    • pp.71-79
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    • 2019
  • Purpose: Recent developments in minimally invasive techniques have the potential to reduce surgical morbidity, promote patient recovery, accelerate surgical procedures, and thus improve cost-effectiveness in case management. In this study, we compared the treatment efficacy and results of supraorbital keyhole approach (SOKA) with those of conventional unilateral frontal craniotomy (CUFC) for traumatic intracerebral hemorrhage (TICH) in the frontal lobe. Methods: We analyzed the data of 38 patients who underwent CUFC (n=30) and SOKA (n=8) and retrospectively reviewed their medical records and radiological findings. Furthermore, we tried to identify the best surgical method for such lesions by including patients who underwent burr hole aspiration and drainage (BHAD) (n=9) under local anesthesia due to various circumstances. Results: The difference in the initial Glasgow coma scale score, operative time, and length of hospitalization between the CUFC and SOKA were statistically significant. All radiological features between the two groups including associated skull fracture, amount of pre- and postoperative hematoma, percentage of complete hematoma removal, pre- and postoperative midline shifting of the hematoma, and development of postoperative delayed hematoma were not statistically significant. Our experience of 46 patients with TICH in the frontal lobe with any of the three different surgical methods including BHAD enabled us to obtain valuable findings. Conclusions: Although it is difficult to insist that one particular approach is more useful than the other, we are confident that SOKA will have more advantages over CUFC in carefully selected patients with frontal TICH depending on the surgical experience of a neurosurgeon.

Adsorption of phosphate in water on a novel calcium hydroxide-coated dairy manure-derived biochar

  • Choi, Yong-Keun;Jang, Hyun Min;Kan, Eunsung;Wallace, Anna Rose;Sun, Wenjie
    • Environmental Engineering Research
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    • v.24 no.3
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    • pp.434-442
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    • 2019
  • The present study investigated a novel calcium hydroxide-coated dairy manure-derived biochar (Ca-BC) for adsorption of phosphate from water and dairy wastewater. The Ca-BC showed much higher adsorption of phosphate than that of dairy manure-derived biochar. The Ca-BC possessed mainly the calcium hydroxide and various functional groups resulting in high reactivity between phosphate and calcium hydroxide in the Ca-BC. The adsorption of phosphate onto Ca-BC followed pseudo-second order kinetic and Freundlich isotherm models indicating chemisorptive interaction occurred on energetically heterogeneous surface of Ca-BC. The maximum adsorption capacity of the Ca-BC was higher than those of iron oxide and zinc oxide-coated biochars, but lower than those of CaO- and MgO-coated biochars. However, the Ca-BC showed high reactivity per surface area for adsorption of phosphate indicating importance of surface functionalization of biochar. On the other hand, the adsorption of phosphate in dairy wastewater on Ca-BC was lower than that in water owing to competition between other anions in wastewater and phosphate. Overall, the Ca-BC would be a low cost and effective adsorbent for recovery of phosphate from water and wastewater.

Pulsed Electromagnetic Field Stimulators Efficacy for Noninvasive Bone Growth in Spine Surgery

  • Fiani, Brian;Kondilis, Athanasios;Runnels, Juliana;Rippe, Preston;Davati, Cyrus
    • Journal of Korean Neurosurgical Society
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    • v.64 no.4
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    • pp.486-494
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    • 2021
  • The growth of pulsed electromagnetic field (PEMF) therapy and its progress over the years for use in post-operative bone growth has been revolutionary in its effect on bone tissue proliferation and vascular flow. However, further progress in PEMF therapy has been difficult due to lack of more evidence-based understanding of its mechanism of action. Our objective was to review the current understanding of bone growth physiology, the mechanism of PEMF therapy action along with its application in spinal surgery and associated outcomes. The authors of this review examined multiple controlled, comparative, and cohort studies to compare fusion rates of patients undergoing PEMF stimulation. Examining spinal fusion rates, a rounded comparison of post-fusion outcomes with and without bone stimulator was performed. Results showed that postoperative spinal surgery PEMF stimulation had higher rates of fusion than control groups. Though PEMF therapy was proven more effective, multiple factors contributed to difficulty in patient compliance for use. Extended timeframe of treatment and cost of treatment were the main obstacles to full compliance. This review showed that PEMF therapy presented an increased rate of recovery in patients, supporting the use of these devices as an effective post-surgical aid. Given the recent advances in the development of PEMF devices, affordability and access will be much easier suited to the patient population, allowing for more readily available treatment options.

Implications of 3-Dimensional Printed Spinal Implants on the Outcomes in Spine Surgery

  • Fiani, Brian;Newhouse, Alexander;Cathel, Alessandra;Sarhadi, Kasra;Soula, Marisol
    • Journal of Korean Neurosurgical Society
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    • v.64 no.4
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    • pp.495-504
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    • 2021
  • Three-dimensional printing (3DP) applications possess substantial versatility within surgical applications, such as complex reconstructive surgeries and for the use of surgical resection guides. The capability of constructing an implant from a series of radiographic images to provide personalized anatomical fit is what makes 3D printed implants most appealing to surgeons. Our objective is to describe the process of integration of 3DP implants into the operating room for spinal surgery, summarize the outcomes of using 3DP implants in spinal surgery, and discuss the limitations and safety concerns during pre-operative consideration. 3DP allows for customized, light weight, and geometrically complex functional implants in spinal surgery in cases of decompression, tumor, and fusion. However, there are limitations such as the cost of the technology which is prohibitive to many hospitals. The novelty of this approach implies that the quantity of longitudinal studies is limited and our understanding of how the human body responds long term to these implants is still unclear. Although it has given surgeons the ability to improve outcomes, surgical strategies, and patient recovery, there is a need for prospective studies to follow the safety and efficacy of the usage of 3D printed implants in spine surgery.

Au/Ag Bilayer Electrode for Perovskite Solar Cells (Au/Ag 이중층 전극 구조를 이용한 페로브스카이트 태양전지)

  • Lee, Junyeong;Jo, Sungjin
    • Korean Journal of Materials Research
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    • v.32 no.1
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    • pp.51-55
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    • 2022
  • Generally, Au electrodes are the preferred top metal electrodes in most perovskite solar cells (PSCs) because of their appropriate work function for hole transportation and their resistance to metal-halide formation. However, for the commercialization of PSCs, the development of alternative metal electrodes for Au is essential to decrease their fabrication cost. Ag electrodes are considered one of the most suitable alternatives for Au electrodes because they are relatively cheaper and can provide the necessary stability for oxidation. However, Ag electrodes require an aging-induced recovery process and react with halides from perovskite layers. Herein, we propose a bilayer Au/Ag electrode to overcome the limitations of single Au and Ag metal electrodes. The performance of PSCs based on bilayer electrodes is comparable to that of PSCs with Au electrodes. Furthermore, by using the bilayer electrode, we can eliminate the aging process, normally an essential process for Ag electrodes. This study not only demonstrates an effective method to substitute for expensive Au electrodes but also provides a possibility to overcome the limitations of Ag electrodes.

Cyanide detection based on natural dyes reaction from blue butterfly pea flowers (Clitoria Ternatea)

  • Chotichayapong, Chatrachatchaya;Kuchaiyaphum, Pusita;Butwong, Nutthaya;Bua-ngern, Worapong
    • Analytical Science and Technology
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    • v.35 no.4
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    • pp.153-160
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    • 2022
  • A green spectrophotometric method for the determination of cyanide has been proposed using, a green reagent, aqueous extract of blue butterfly pea. The test tube was filled with anthocyanin rich extract (pH 6) and cyanide solution. The reaction was kept constant for 10 minutes at room temperature. The reaction mixture changed color from blue to green as the amount of CN-ions increased. The 620 nm peak intensity increased with CN concentration. Therefore, this wavelength was used for all cyanide analyses. The cyanide calibration curve had a linear range of 0.25-1.00, 1.00-4.00, and 4.00-10.00 mg/L, with a satisfactory correlation coefficient of 0.99 and a LOD of 0.57 mg/L. The recovery ranged from 8.33 to 76.94 percent, indicating that this method is inaccurate at low cyanide concentrations. The intra-day and intermediate precision relative deviations were 0.391-0.871 % and 1.112-1.583 %. An H-bond forms between the C-4 group of the B-carbonyl ring and the HCN molecule according to the B3LYP/TZVP calculation. The method is convenient for cyanide concentrations above the LOQ of 1.09 mg/L, cost-effective, and capable of reducing toxic solvents with acceptable precision. The method could also be used to detect total cyanide in biological, environmental, and industrial waste samples.

Biotechnological Approaches for Biomass and Lipid Production Using Microalgae Chlorella and Its Future Perspectives

  • Sujeong Je;Yasuyo Yamaoka
    • Journal of Microbiology and Biotechnology
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    • v.32 no.11
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    • pp.1357-1372
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    • 2022
  • Heavy reliance on fossil fuels has been associated with increased climate disasters. As an alternative, microalgae have been proposed as an effective agent for biomass production. Several advantages of microalgae include faster growth, usage of non-arable land, recovery of nutrients from wastewater, efficient CO2 capture, and high amount of biomolecules that are valuable for humans. Microalgae Chlorella spp. are a large group of eukaryotic, photosynthetic, unicellular microorganisms with high adaptability to environmental variations. Over the past decades, Chlorella has been used for the large-scale production of biomass. In addition, Chlorella has been actively used in various food industries for improving human health because of its antioxidant, antidiabetic, and immunomodulatory functions. However, the major restrictions in microalgal biofuel technology are the cost-consuming cultivation, processing, and lipid extraction processes. Therefore, various trials have been performed to enhance the biomass productivity and the lipid contents of Chlorella cells. This study provides a comprehensive review of lipid enhancement strategies mainly published in the last five years and aimed at regulating carbon sources, nutrients, stresses, and expression of exogenous genes to improve biomass production and lipid synthesis.

IgY: A Key Isotype and Promising Antibody for the Immunoprophylaxis Therapy of Infectious Bursal Disease Virus Infections

  • Sanaullah Sajid;Sajjad ur Rahman;Mashkoor Mohsin;Zia ud Din Sindhu
    • Microbiology and Biotechnology Letters
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    • v.50 no.3
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    • pp.430-435
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    • 2022
  • The infectious bursal disease (IBD) is a highly contagious and acute poultry disease caused by Birnavirus. However, the vaccination is the only disease prevention, but several factors impeded vaccine development. Thus, a need for time to develop a novel technique for managing and treating respiratory diseases in poultry birds. Passive immunization is a hope and a possible alternative used in birds to meet this need. The current research attempted to produce egg yolk-based polyclonal antibodies against the IBD virus. The benefits of IgY include ease of extraction, lack of reaction with mammalian Fc receptors, and low production cost. Commercial layers were immunized with inactivated IBD virus subcutaneously according to the treatment regimen. The eggs were gathered daily, and yolk antibodies were extracted with the ammonium sulfate precipitation technique. The use of an indirect hemagglutination test demonstrated that IgY was IBD-specific. Until the end of the experiment, the specific IgY immunoglobulins did not lose activity when stored at 4℃. The specific immunoglobulin (IgY) treated challenged birds were demonstrated 92% recovery in comparison to the control group. The study implies that the IBDV specific IgY is an easily prepared and rich source of antibodies and offers an alternative therapeutic agent to cure IBD-infected birds.

Design of resource efficient network reprogramming protocol (자원 효율적인 네트워크 리프로그래밍 프로토콜 설계)

  • Choi, Rock-Hyun;Hong, Won-Kee
    • Journal of Korea Society of Industrial Information Systems
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    • v.15 no.3
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    • pp.67-75
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    • 2010
  • Network reprogramming is a technology that allows several sensor nodes deployed in sensor field to be repaired remotely. Unlike general communication in sensor network where small amount of data is transferred, network reprogramming requires reliable transfer of large amount of data. The existing network reprogramming techniques suffers high cost and large energy consumption to recover data loss in node communication. In this paper, a cluster based network reporgramming scheme is proposed for sensor network. It divides sensor field into several clusters and chooses a cluster header in charge of data relay to minimize duplicated transmission and unnecessary competition. It increases reliability by effective error recovery through status table.