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Floristic Study of Woraksan National Park in Korea (월악산 국립공원의 관속식물상)

  • Jang, Chang-Seok;Yang, Sun-Gyu;Jang, Hyun-Do;Lee, Ro-Young;Park, Min-Su;Kim, Ki-Hong;Oh, Byoung-Un
    • Korean Journal of Plant Resources
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    • v.28 no.1
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    • pp.35-63
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    • 2015
  • A floristic, field research was conducted from March 2005 to October 2012 the Woraksan National Park (N $36^{\circ}46^{\prime}{\sim}36^{\circ}59^{\prime}$, E $128^{\circ}02^{\prime}{\sim}128^{\circ}19^{\prime}$) to characterize the flora of the region. Especially, we divided the surveyed region into nine representative collection areas based on floristic components were compared and analyzed. This field study discovered significant plants in various categories. The 41 surveys revealed that the vascular plants in this region comprised 815 taxa: 116 families, 429 genera, 717 species, 4 subspecies, 78 varieties and 16 forms. In this study, 80 taxa were firstly recorded from this region. Korean endemic plants numbered 22 taxa, and the fifteen taxa rare plants designated by Korean Forest Service as were found in this region. The taxa in the category II of rare and endangered plants and the taxa with the higher rank than the third degree among the floristic regional indicator plants designated by Korean Ministry of Environment were one and 56, respectively. From a geographical perspective, limited distributions of Matteuccia struthiopteris, Spiraea trichocarpa, and Aster tataricus at a latitudes higher than that of Woraksan National Park. Moreover, this study has confirmed that the Woraksan National Park is the species diversity center for Asarum koreanum, Elsholtzia angustifolia, and Allium linearifolium in the central province of the Korean peninsula. Inaddition, the naturalized plants of 54 taxa were recorded.

Green Productivity Analysis of the Logistics Industry for the Global Competitiveness (물류산업의 녹색생산성 평가와 국제경쟁력 강화방안)

  • Choi, Yong-Rok
    • International Commerce and Information Review
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    • v.14 no.4
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    • pp.89-107
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    • 2012
  • Recently, the successful appointment of the general directorate of GCF (Green Climate Fund) in Songdo of Korea made a great history for the golden triangle with GGGI (global Green Growth Institute) and GTC (Green Technology Center). Now, Korea became the Mecca for the global green growth and it gave a great opportunity foe the Korea to lead the global economy in the future. However, to successfully manage the GCF, the Korean government should show their willingness as well as the readiness for the green prowth and green productivity. It is really hard for the Korea, since it takes the second rank for the growth rate of carbon dioxide emission in the world. To overcome this shameful status, it should make the best effort to promote the green productivity, especially in a field of logistics industry, because it takes 21% of global CO2 emission, the second largest portion. The research aims to systematically introduce the Global Malmquist-Luenberger Index (GML) and to evaluate the logistics industry of Korea based on the GML approach. It concludes the innovative technology is utmost important to improve the green productivity of the logistics industry and thus the Korean government should make more aggressive role to fill this missing link in the innovation network.

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Regenerative effect of recombinant human bone morphogenetic protein-2/absorbable collagen sponge (rhBMP-2/ACS) after sequestrectomy of medication-related osteonecrosis of the jaw (MRONJ)

  • Min, Song-Hee;Kang, No-Eul;Song, Seung-Il;Lee, Jeong-Keun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.46 no.3
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    • pp.191-196
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    • 2020
  • Objectives: Beyond the original application approved by the U.S. Food and Drug Administration, recombinant human bone morphogenetic protein-2 (rhBMP-2) is used for medication-related osteonecrosis of the jaw (MRONJ) treatment because of its bone remodeling enhancement properties. The purpose of the study was to investigate the bone formation effect of rhBMP-2/absorbable collagen sponge (ACS) in patients with MRONJ. Materials and Methods: In this retrospective cohort study, 26 female patients diagnosed with MRONJ and who underwent mandibular sequestrectomy at Ajou University Dental Hospital from 2010 to 2018 were included. The experimental group was composed of 18 patients who received rhBMP-2/ACS after sequestrectomy, while the control group was composed of 8 patients who did not receive rhBMP-2/ACS after sequestrectomy. A total dose of 0.5 mg of rhBMP-2 was used in the experimental group at a concentration of 0.5 mg/mL. Follow-up panoramic X-rays were taken immediately after the surgery and more than 6 months after the surgery. Using those X-rays, a radiographic index of bone defect area was calculated using the modified Ihan Hren method, which measures radiographic density of the normal bone and the defect site. Results: This study suggests that rhBMP-2 contributes to new bone formation. The mean radiographic index immediately after surgery and more than 6 months after the surgery for the experimental group was 68.4% and 79.8%, respectively. The mean radiographic index immediately after surgery and more than 6 months after the surgery for the control group was 73.4% and 76.7%, respectively (Wilcoxon signed rank test, P>0.05). The mean radiographic index increased 11.4% in the experimental group and 3.27% in the control group (Mann-Whitney U-test, P<0.05). Conclusion: Based on the results, use of rhBMP-2/ACS on bone defect sites after sequestrectomy could be a successful strategy for treatment of MRONJ patients.

3D Model Retrieval Using Sliced Shape Image (단면 형상 영상을 이용한 3차원 모델 검색)

  • Park, Yu-Sin;Seo, Yung-Ho;Yun, Yong-In;Kwon, Jun-Sik;Choi, Jong-Soo
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.45 no.6
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    • pp.27-37
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    • 2008
  • Applications of 3D data increase with advancement of multimedia technique and contents, and it is necessary to manage and to retrieve for 3D data efficiently. In this paper, we propose a new method using the sliced shape which extracts efficiently a feature description for shape-based retrieval of 3D models. Since the feature descriptor of 3D model should be invariant to translation, rotation and scale for its model, normalization of models requires for 3D model retrieval system. This paper uses principal component analysis(PCA) method in order to normalize all the models. The proposed algorithm finds a direction of each axis by the PCA and creates orthogonal n planes in each axis. These planes are orthogonalized with each axis, and are used to extract sliced shape image. Sliced shape image is the 2D plane created by intersecting at between 3D model and these planes. The proposed feature descriptor is a distribution of Euclidean distances from center point of sliced shape image to its outline. A performed evaluation is used for average of the normalize modified retrieval rank(ANMRR) with a standard evaluation from MPEG-7. In our experimental results, we demonstrate that the proposed method is an efficient 3D model retrieval.

Survival analysis on the business types of small business using Cox's proportional hazard regression model (콕스 비례위험 모형을 이용한 중소기업의 업종별 생존율 및 생존요인 분석)

  • Park, Jin-Kyung;Oh, Kwang-Ho;Kim, Min-Soo
    • Journal of the Korean Data and Information Science Society
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    • v.23 no.2
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    • pp.257-269
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    • 2012
  • Global crisis expedites the change in the environment of industry and puts small size enterprises in danger of mass bankruptcy. Because of this, domestic small size enterprises is an urgent need of restructuring. Based on the small business data registered in the Credit Guarantee Fund, we estimated the survival probability in the context of the survival analysis. We also analyzed the survival time which are distinguished depending on the types of business in the small business. Financial variables were also conducted using COX regression analysis of small businesses by types of business. In terms of types of business wholesale and retail trade industry and services were relatively high in the survival probability than light, heavy, and the construction industries. Especially the construction industry showed the lowest survival probability. In addition, we found that construction industry, the bigger BIS (bank of international settlements capital ratio) and current ratio are, the smaller default-rate is. But the bigger borrowing bond is, the bigger default-rate is. In the light industry, the bigger BIS and ROA (return on assets) are, the smaller a default-rate is. In the wholesale and retail trade industry, the bigger bis and current ratio are, the smaller a default-rate is. In the heavy industry, the bigger BIS, ROA, current ratio are, the smaller default-rate is. Finally, in the services industry, the bigger current ratio is, the smaller a default-rate is.

Effects of Dystocia on the Postpartum Complications, Milk Production and Reproductive Performance in Dairy Cows

  • Kim, Dong-Uk;Lee, Soo-Chan;Jeong, Jae-Kwan;Choi, In-Soo;Moon, Sung-Ho;Kang, Hyun-Gu;Kim, Ill-Hwa
    • Journal of Veterinary Clinics
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    • v.33 no.2
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    • pp.87-92
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    • 2016
  • This field study investigated the effects of dystocia on the postpartum complications, milk production, and reproductive performance in Holstein dairy cows. Calving difficulty was scored on a rank scale of 1 to 5. Cows with a calving score of three or higher were judged to have dystocia. The cows (n = 565) were categorized based on the presence (n = 61) or absence (n = 504, control) of dystocia. The incidence of retained placenta (45.9% vs. 16.3%), metritis (39.3% vs. 17.1%), endometritis (47.5% vs. 16.3%) and pyometra (9.8% vs. 1.2%) were greater in cows from the dystocia group than those from the control group (p < 0.0001); however, there was no difference in the incidence of metabolic disorders (32.8% vs. 31.0%) between the two groups (p > 0.05). The prevalence of culling was higher in cows from the dystocia group (26.2%) than in those from the control group (14.5%, p < 0.05). During the 5-month postpartum period, milk production was lower (p < 0.05) in cows from the dystocia group than in those from the control group. Furthermore, the hazard of insemination by 150 days in milk (DIM) was lower in cows from the dystocia group (hazard ratio [HR] = 0.64, p < 0.005) than in those from the control group. Logistic regression analysis revealed that the odds ratio for the probability of pregnancy after the first artificial insemination was 0.36 times (p < 0.05) higher in cows from the dystocia group than in those from the control group. The hazard of pregnancy by 360 DIM was lower in cows from the dystocia group (HR = 0.45, p = 0.0001) than in those from the control group. In conclusion, dystocia resulted in increased postpartum complications, and decreased milk production and reproductive performance in Holstein dairy cows, leading to increased culling.

Efficacy of First-Line Targeted Therapy in Real-World Korean Patients with Metastatic Renal Cell Carcinoma: Focus on Sunitinib and Pazopanib

  • Kim, Myung Soo;Chung, Ho Seok;Hwang, Eu Chang;Jung, Seung Il;Kwon, Dong Deuk;Hwang, Jun Eul;Bae, Woo Kyun;Park, Jae Young;Jeong, Chang Wook;Kwak, Cheol;Song, Cheryn;Seo, Seong Il;Byun, Seok-Soo;Hong, Sung-Hoo;Chung, Jinsoo
    • Journal of Korean Medical Science
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    • v.33 no.51
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    • pp.325.1-325.10
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    • 2018
  • Background: To evaluate survival outcomes and prognostic factors for overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) who received sunitinib (SU) and pazopanib (PZ) as first-line therapy in real-world Korean clinical practice. Methods: Data of 554 patients with mRCC who received SU or PZ at eight institutions between 2012 and 2016 were retrospectively reviewed. Based on the targeted therapy, the patients were divided into SU (n = 293) or PZ (n = 261) groups, and the clinicopathological variables and survival rates of the two groups were compared. A multivariable Cox proportional hazard model was used to determine the prognostic factors for OS. Results: The median follow-up was 16.4 months (interquartile range, 8.3-31.3). Patients in the PZ group were older, and no significant difference was observed in the performance status (PS) between the two groups. In the SU group, the dose reduction rate was higher and the incidence of grade 3 toxicity was more frequent. The objective response rates were comparable between the two groups (SU, 32.1% vs. PZ, 36.4%). OS did not differ significantly between the two groups (SU, 36.5 months vs. PZ, 40.2 months; log-rank, P = 0.955). Body mass index, Eastern Cooperative Oncology Group PS > 2, synchronous metastasis, poor Heng risk criteria, and liver and bone metastases were associated with a shorter OS. Conclusion: Our real-world data of Korean patients with mRCC suggested that SU and PZ had similar efficacies as first-line therapy for mRCC. However, PZ was better tolerated than SU in Korean patients.

Comparison of Dysphagia Rehabilitation Therapy with Natural Recovery on Swallowing Ability among Acute Stroke Patients (연하재활치료의 효과와 자연회복과의 비교연구 - 급성기 뇌졸중 환자를 중심으로 -)

  • Heo, S.Y.;Kim, K.K.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.8 no.2
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    • pp.109-118
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    • 2014
  • The purpose of this study was to compare the effectiveness of rehabilitation therapy with natural recovery in patients who had dysphagia due to stroke. Swallowing functions were examined on a total of 98 patients with stroke-caused dysphagia based on a videofluoroscopic swallowing study (VFSS) for 8 weeks. The each group was evaluated with DOSS, DSS and FOSS to assess swallowing ability in the first week and re-evaluated in the $8^{th}$ week during the session for investigating the recovery status. The author compared the above initial data and follow-up data using a Mann-Whitney U test, Kruskal-Wallis test and Wilcoxon's Signed Rank test, ANCOVA to confirm statistically controlling for the effects of other continuous variables, performed by IBM SPSS Statistics 20.0 for windows. There was statistically significant recovery in the experimental group except measure of DOSS (p>0.05). In the control group, it showed improvement in all the scales(p<0.05). After terminating each session, the comparison of the two group of patients showed statistical significant differences in DSS and FOSS(p<0.05). These results suggest that possibility of natural neurologic recovery has positive effects on early stage of dysphagia caused by stroke.

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A Study on the Induction of Infertility of Largemouth Bass (Micropterus salmoides) by CRISPR/Cas9 System (CRISPR/Cas9 System을 활용한 배스의 불임 유도에 대한 연구)

  • Park, Seung-Chul;Kim, Jong Hyun;Lee, Yoon Jeong
    • Korean Journal of Environment and Ecology
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    • v.35 no.5
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    • pp.503-524
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    • 2021
  • A largemouth bass (Micropterus salmoides) is an ecosystem disturbance fish species at the highest rank in the aquatic ecosystem, causing a serious imbalance in freshwater ecosystems. Although various attempts have been made to eradicate and control largemouth bass, no effective measures were found. Therefore, it is necessary to find an approach to maximize the effective population reduction based on the unique characteristics of largemouth bass. This study used the transcriptome analysis to derive 182,887 unigene contigs and select 12 types of final target sequences for applying the CRISPR/Cas9 system in the genes of IZUMO1 and Zona pellucida sperm-binding protein, which are proteins involved in sperm-egg recognition. After synthesizing 12 types of sgRNA capable of recognizing each target sequence, 12 types of Cas9-sgRNA ribonucleoprotein (RNP) complexes to be used in subsequent studies were prepared. This study searched the protein-coding gene of sperm-egg through the Next Generation Sequencing (NGS) and edited genes through the CRISPR/Cas9 system to induce infertile individuals that produced reproductive cells but could not form fertilized eggs. Through such a series of processes, it successfully established a composition development process for largemouth bass. It is judged that this study contributed to securing the valuable basic data for follow-up studies to verify its effect for the management of ecological disturbances without affecting the habitat of other endemic species in the same water system with the largemouth bass.

Differences of Physiological Responses According to Growing Conditions Between Superior Family and Inferior Family in Pinus densiflora (소나무 생장 우수가계와 불랑가계의 생육환경에 따른 생리적 반응 차이)

  • Oh, Chang-Young;Han, Sang-Urk;Kim, Chang-Soo
    • Korean Journal of Breeding Science
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    • v.40 no.2
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    • pp.136-142
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    • 2008
  • We conducted this study to compare physiological response according to growing conditions between superior and inferior family of Pinus densiflora. In 1981, open-pollinated (OP) progenies of P. densiflora were planted in Chuncheon (CC) and Naju (NJ). We selected KW2 as a superior family and KW23 as a inferior family based on volume index among 30 OP progenies. We calculated general combining ability of each 30 OP progenies in each sites, and compared family growth rank. We collected needles of selected families in CC and NJ, and analyzed chlorophyll content, nitrated reductase (NR) activity, nitrogen content, and superoxide dismutase (SOD) acitivity. In CC, chlorophyll content and nitrogen content were more in needles of KW2 than those of KW23. In NJ, KW2 showed higher NR activity than KW23, and according to site, families in CC showed higher NR activity than those in NJ. SOD activities of both families were higher in NJ, and KW23 showed higher activity than KW2 in both sites. Consequently, inconsistency of the growth performance of two families was caused by different genetic and physiological responses.