• Korean Journal of Veterinary Service
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• v.38 no.2
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• pp.141-144
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• 2015

An equine herpesvirus-4 (EHV-4) was isolated in nasal swabs collected in a horse showing respiratory clinical signs. Equine dermis cells inoculated with the sample were observed with characteristic viral cytopathic effects after 3 days of postinoculation and the infected cells exhibited bright intracelluar fluorescence by indirect immunofluorescence assay. At the nucleotide level, the partial glycoprotein B gene of the Korean EHV-4 isolate (K001) had 99.9% identity to 1942 strain (GenBank No. M26171). To author's knowledge, the report describes the first isolation and partial characterization of EHV-4 in Korea. The virus can be used for further study of EHV-4.

• Journal of Veterinary Clinics
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• v.26 no.1
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• pp.69-71
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• 2009

A 2-year-old, female Thoroughbred racehorse was referred to the Equine Hospital of Korea Racing Authority. The horse was presented with fluctuant swelling at the base of the left temporal ear tooth. We performed physical examination, radiography and ultrasonography, and diagnosed as dentigerous cyst on the left temporal ear tooth-(dentigerous cyst). The horse was treated with removal of a dentigerous cyst(aural fistula). After surgical procedure for 12 days, the patient was recovered completely.

• Journal of Veterinary Clinics
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• v.35 no.5
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• pp.247-249
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• 2018

A 3-year-old black Thoroughbred colt weighing 500 kg was admitted to the Equine Hospital of Korea Racing Authority (KRA) due to the chronic gait abnormality of the hindlimbs. The history revealed that the patient had run and fallen onto the fence of the farm about at the age of 1 year old and the lameness had been worsening insidiously since the accident. The degree of lameness was 2/5 in accordance with the AAEP lameness grading system in both hindlimbs at hand walking and trot. The lameness was exacerbated at lunging clockwise and counterclockwise on both hindlimbs. The definitive diagnosis of the bilateral osteoarthritis of coxofemoral joint was established using radiography under general inhalation anesthesia. The prognosis was considered to be poor with low expectancy for racing and the colt was expelled from the racecourse eventually. The clinicians are required to consider the possibility of osteoarthritis of coxofemoral joint presented with chronic hindlimb lameness although it is rare. This is the first report on the bilateral osteoarthritis coxofemoral joint in Republic of Korea.

• Journal of Veterinary Clinics
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• v.30 no.5
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• pp.394-398
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• 2013

An 3-year-old female Thoroughbred horse was referred with moderate lameness (3/5G) and mild heat on right hoof of forelimb. She was diagnosed with white line disease (WLD) that was included hoof wall separation by radiographic examination and hoof percussion. Treatment was carried out hoof wall resection at first, followed by disinfection of affected hoof and shod modified heart bar. On the re-examination after 4 months, we could find a results which had no lameness, gas pocket in the white line and clinical signs was improved. Subsequently, she was trained and raced after 8 months of diagnosis. So, we supposed that resection of wall and therapeutic shoeing was good for WLD including hoof separation.

• Korean Journal of Veterinary Research
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• v.50 no.3
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• pp.253-257
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• 2010

A 3-year-old female Thoroughbred racehorse was presented following the accidental oral and skin administration of amitraz. This case report describes the clinical signs and the treatment of this horse. Clinical signs of amitraz toxicosis are associated with the stimulation of alpha2-adrenergic receptors. Amitraz is seldom fatal because the effects can be reversed by alpha2-adrenergic antagonists. The horse displayed typical clinical signs of colic, including pawing, small hard drops, tranquillisation, depression, ataxia, muscular incoordination and impaction colic lasting up to 7 days. The syndrome was accompanied by mild dehydration. The horse survived after persistent symptomatic treatment, including the giving of intravenous fluids, antibiotics, multiple doses of mineral oil per os, nonsteroidal anti-inflammatory drugs and dexamethasone intramuscularly and intravenously.

• Journal of Animal Science and Technology
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• v.51 no.2
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• pp.129-134
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• 2009

The aim of this study was to estimate genetic parameters and annual trends on the racing performance of Thoroughbred horses by a statistical analysis of the resulting records. We used the racing results of 245,979 observations for 13,458 horses recorded in 19 years of race held at Seoul and Busan racing tracks, provided by Korea Racing Authority. After a careful adjustment of some variables such as racing times, jockey and trainer numbers and the average prize a horse won, we selected significant factors that explain the result of racing records of a horse by stepwise AIC and BIC methods. The estimated heritability and repeatability were 0.322 and 0.332, respectively. The average of annual phenotypic and genetic improvement was -0.166 seconds and -0.161 seconds, respectively. Based on the statistical approach, we established reasonable animal model of well-set variables, which is important in the study on estimating performance of racing horses.

• Korean Journal of Veterinary Service
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• v.46 no.4
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• pp.263-268
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• 2023

Despite regular vaccinations, equine influenza virus (EIV) and Streptococcus equi subsp. equi (strangles) are the cause of highly contagious respiratory infections in horses. Many recent studies have reported that the concurrent administration of two vaccines could simplify horse management and minimize veterinary expenses. However, there is little information available regarding the efficacy of concurrent vaccinations against EIV and strangles. In this study, we evaluated EIV-specific antibody responses following the single EIV vaccination with the recombinant viral-vectored EIV vaccine or concurrent vaccination with the EIV and inactivated strangles vaccines. Blood samples were collected at 1-, 2-, 4-, and 8 weeks post-immunization (wpi) from each group. EIV-specific antibodies were evaluated by enzyme-linked immunosorbent assay (ELISA) and hemagglutination inhibition (HAI) assay. Both single and concurrent vaccination showed similar levels of EIV-specific serum immunoglobulin g (IgG) at 1 and 2 wpi. However, at 4 to 8 wpi, the EIV-only vaccination group showed significantly higher serum IgG levels than those from the concurrently vaccinated group. The HAI titers showed similar trends as the ELISA data, except at 8 wpi when both groups presented HAI titers with no significant differences. These data demonstrate that the concurrent vaccination against EIV and strangles could compromise the humoral immune response to equine influenza between vaccination intervals, which suggests the use of the consecutive vaccination protocol for EIV and strangles rather than concurrent vaccination.

• Journal of Veterinary Clinics
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• v.35 no.1
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• pp.22-25
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• 2018

A 7-year-old, 453 kg, thoroughbred-cross mare showed depression, severe nasal bleeding, diffuse swelling, and distortion of the facial contour. Physical and radiographic examinations revealed an open nasal bone fracture. Surgery was conducted under sedation with the horse in a standing position. Two holes were drilled directly above and below the fracture line. The nasal bone was raised to the normal position by inserting a periosteal elevator through the holes. Orthopedic wire was used to secure the fractured nasal bones through the holes. The horse recovered from sedation without complication. Sutures were removed three weeks after surgery. The nasal bone fracture appeared well-recovered morphologically and the recovery was confirmed by radiography. A wire fixation method is recommended to treat nasal bone fracture in a horse.

• Journal of Veterinary Clinics
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• v.31 no.5
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• pp.461-465
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• 2014

A 3-year-old colt Thoroughbred horse was referred with obvious lameness (3/5G) and mild heat and pain on left hoof of forelimb. He was diagnosed with quarter cracks that have a typical conformation of sheared heel, which are a different length and height between medial/lateral heels. Various materials and techniques were carried out to repair quarter cracks by using many different kinds of clips, bar shoes on fifth times for about 10 months. It worked on him without pain and heat on the cracked hoof, and then he could retrain for racing from the 36th weeks beginning of therapeutic shoeing. We suggested that especially fiberglass reinforced plastic (FRP) material and therapeutic shoeing were a great help to treat quarter cracks induced by sheared heel.

• Journal of Life Science
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• v.26 no.7
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• pp.855-867
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• 2016

The horse is relatively earlier domesticated animal species. Domesticated horses have been selected for their ability of racing, robustness, and disease-resistance. As a result, the thoroughbred horse genome has been condensed many genotypes related to exercise ability. In recent years, with the advent of NGS technologies, many studies were concentrated on finding superior genetic species in the horse genome in terms of genomics. Consequently, GWAS (Genome-wide Association study) is applied to horse genome, then genetic marker is revealed for superior racing ability. In addition, RNA-Seq is utilized as a method for analyze of whole transcript profiling in specific samples. By using this approach, specific gene expression patterns and transcript sequences can be revealed in various samples such as each individual, before and after exercise state, and each tissue. DNA methylation, a strong factor that regulate gene expression without the change of DNA sequence, have got a lot of attention. In horse genome, exercise- or individual-specific DNA methylation patterns were detected, and could be useful to develop selective marker of superior horses. MicroRNAs inhibit gene expression, and transposable elements accounted for half of the mammalian genome. These two elements are the crucial factors in functional genomics, and could be applied to the selection of superior horses. As the functional genomics and epigenomics advance, then these technologies introduced in this paper were applied to select superior horses. In this paper, the studies for selection of superior horses through genetic technologies, and development possibilities of these studies were discussed.