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Renal Failure in a Female Muskrat (암컷 사향쥐(Ondatra zibethicus)의 신부전)

  • Ullah, HM Arif;Elfadl, A.K.;Park, SunYoung;Chung, Myung-Jin;Son, Ji-Yoon;Yun, Hyun-Ho;Park, Jae-Min;Yim, Jae-Hyuk;Jung, Seung-Jun;Park, Jin-Kyu;Jeong, Kyu-Shik
    • Journal of Life Science
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    • v.30 no.7
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    • pp.630-633
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    • 2020
  • Renal failure syndrome in wild mammals is infrequently reported. Muskrat (Ondatra zibethicus) is a medium-sized rodent known to carry many diseases but rarely exhibiting renal failure. A six-month old female muskrat was submitted to our laboratory for pathological diagnosis, and necropsy revealed severe renal damage with sand-like lithiasis in the ureter, renal calculi, and hydronephrosis. All major organs, including the cerebrum, also showed systemic hemorrhage and calcification which may have been due to uremia induced by renal failure. Histopathologically, necrosis and microcalcification were detected in the renal cortex and the medulla, especially in the proximal convoluted tubules and collecting ducts of the kidney. Significant hyalinization of the glomeruli was also observed, and this suggested chronic nephritis. These findings would support mycotoxic effects, particularly on the kidney. Moreover, infiltration of neutrophils and mononuclear cells was observed in the lung and of plasma cells in the spleen. The definitive cause of the toxic effects in this case of muskrat renal failure could be attributed to contaminated food.

THE CHANGE OF VITAL SIGNS IN STEPS WHEN IT IS EXTRACTED A THIRD MOLOR OF MANDIBLE (제3대구치 발치시 단계별 생체징후(vital sign)의 변화에 대한 연구)

  • Oh, Hae-Soo;Kang, Hee-In;Choi, Bin;Park, Jun-Woo;Sin, Sung-Soo;Choi, Je-Won;Lee, Sun-Keun;Kim, Mi-Ja
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.32 no.2
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    • pp.142-150
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    • 2006
  • PURPOSE : The 3rd molar extraction of mandible is common in out-patient office of oral and maxillofacial surgery. And it is dynamic minor operation with changes of vital signs. most of patients are already sensitive about their dental treatment. The changes of emotion are reached to the highest level when patients is laid down to be treated on unit chair. It can be induced to undesirable accidents as to this fear. The undesirable complications are nausea, vomiting, hyperventilation, dyspnea, syncope, shock and so on. The severe changes of vital signs may influence their behavior and make serious medical malpractice or suit such as fracture of dental instruments and injury of proximal area. METHOD AND PATIENTS : A total of 99 selected normal patients were reviewed. Among this, 70 patients(43 men, 27 women with statistical significance) were included in this study. Each steps(pre-anesthesis, 5 minutes after anesthesis, just after mucogingival incision, just after tooth section, just after suture and gauze biting) were investigated for a change of a vital signs. It is analyzed to 2 categories,"Means" and "Tendency". The "Means" is the amount of vital signs changed in comparison with pre-step during operation. That means is the amount of vital changes by each step operation. Next, " Tendency" is changes of vital signs in comparison with step1 during operation. RESULT : This is the changing tendency of vital signs with time. That is active effect of fear and pain. Thus this "Means" and "Tendency" will present a sudden changes of vital signs and it can lead to more safe treatment. CONCLUSION : Thus, the purpose of this study is, through careful operation in each step, to less on patients' complication and increase trust between patient and OMFS. This study is a first article shown with the amount of "Means" and "Tendency" in vital signs, when a third molar of mandible is extracted. This study will be base study of patients with general diseases, because it selected only patients without general diseases.

A STUDY ON MICROLEAKAGE ACCORDING TO RESTORATION METHOD OF COMPOMER UNDER SALIVA CONTAMINATION (타액 오염하에서 수복방법에 따른 컴포머의 미세누출에 관한 연구)

  • Kong, Seok-Bae;You, Seung-Hoon;Kim, Jong-Soo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.34 no.1
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    • pp.73-80
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    • 2007
  • Compomer that release fluoride could be used on proximal caries of child effectively. But oral cavity is always wet, so saliva inhibits bonding of tooth and compomer. When the saliva exist on bonding, it can be occured microleakages. The purpose of this study was to evaluate the influence of salivary contamination on compomer restoration and degree of microleakage according to restoration methods. Dyract $AP^{(R)}$ and prime and $bond^{(R)}$ NT was applied by the manufacture s instructions. Elipar Trilight was applied for light curing. Saliva pool was made for reconstruction of oral cavity. Two premolar was embedded in acrylic resin. After class II cavity preperation, Dyract $AP^{(R)}$ was restored under several condition, the specimen was thermocycled 500 times with 30 second dwell time. 0.5% methylene blue was used for microleakage test. Micoleakage was measured by the ratio of the infiltration length to occlusal and gingival side interface. Data were analyzed statistically using Kruskal Wallis Test, Mann-Whitney Test. The Result were as follows ; 1. In occlusal side, there were no statistical differences. 2. In gingival side, there were no statistical differences in Group III ($ContactMatrix^{TM}$, Rubber dam, $Oraseal^{(R)}$), Group IV (No saliva contamination). 3. In gingival side, there were no statistical differences in Group I$(ContactMatrix^{TM})$, II($ContactMatrix^{TM}$, Rubber dam). 4. In gingival side, there were statistical differences in Group I$(ContactMatrix^{TM})$, II($ContactMatrix^{TM}$, Rubber dam).

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Marginal Fidelity and Fracture Strength of OPTIMAL PRESSABLE CERAMIC Crown according to Margin Types (OPTIMAL PRESSABLE CERAMIC 금관의 변연형태에 따른 변연적합도와 파절강도에 관한 연구)

  • Lee, Ju-Seog;Kim, Ki-Suk
    • Journal of Dental Rehabilitation and Applied Science
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    • v.16 no.1
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    • pp.13-25
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    • 2000
  • Optimal Pressable Ceramic is one of the all-ceramic restorations with a shaded translucent pressed core and layering porcelains. The purpose of this study was to evaluate the marginal fidelity according to margin types and measurement sites, and to evaluate fracture strength according to margin types. Twenty seven OPC crowns made according to 3 types of cervical finishing lines were used in this study. Marginal gaps were measured before and after cementation. A Steromicroscope(SZ-ST(R), Olympus, Japan) was used to measure the space between the margin of OPC crown and the finishing line of metal model. Marginal gaps were measured at the labial, mesial, lingual and distal site, which were demonstrated in advance. Fracture strength testing was carried out using an Instron(Model M100EC, Mecmesin, England) at a cross head speed of 5 mm/min. All crowns were loaded until catastrophic failures occurred. The result were as follow: 1. In comparison according to variable margin before cementation, the marginal gap were increased in chamfer margin($47.50{\pm}18.39{\mu}m$), $120^{\circ}$shoulder margin ($55.21{\pm}14.4{\mu}m$) and $90^{\circ}$shoulder margin($71.18{\pm}13.30{\mu}m$) in ascending order, and there were significant differences between chamfer margin and $90^{\circ}$shoulder margin, $120^{\circ}$shoulder margin and between $120^{\circ}$shoulder margin and $90^{\circ}$shoulder margin respectively(p<0.05). 2. In comparison according to variable margin after cementation, the gap discrepancies were increased in chamfer margin($60.78{\pm}30.37{\mu}m$), $120^{\circ}$shoulder margin($66.67{\pm}11.18{\mu}m$) and $90^{\circ}$shoulder margin($85.78{\pm}17.23{\mu}m$) in ascending order, but there was significant difference only between chamfer margin and $90^{\circ}$shoulder margin(p<0.05). 3. Labio-lingual points showed a better marginal fidelity than that of proximal point(p<0.05). 4. Chamfer margin($48.76{\pm}8.45kgf$) showed higher fracture strength than $120^{\circ}$ shoulder margin($40.57{\pm}7.90kgf$) and $90^{\circ}$ shoulder margin(32.7.90kgf) (p<0.05), but there was significant difference only between chamfer margin and $90^{\circ}$ shoulder margin(p<0.05).

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The Effect of Sensory Integrative Intervention on Postural Control and Occupational Performance (Play) of the Preschool Child With Postural Disorder: Case Study Using Goal Attainment Scale (GAS) (감각통합 중재가 취학 전 자세조절장애 아동의 자세조절과 작업수행(놀이)에 미치는 영향: 목표성취척도(Goal Attainment Scale)를 사용한 사례보고)

  • Ryu, Sung-Un;Kim, In-Sun;Kim, Kyeong-Mi
    • The Journal of Korean Academy of Sensory Integration
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    • v.11 no.2
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    • pp.1-11
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    • 2013
  • Objective : The purpose of this study is to verify the effect of sensory integrative intervention on postural control and occupational performance (play) of the preschool child with postural disorder. Methods : Subject of this study was a 5 years and 8 month old boy. The subject underwent a sensory integration (SI) treatment which was part of the SI clinic course administered by the Korean Sensory Integration Society, in 2012. The treatment goal and treatment plan had established based on the evaluation results. Treatment was done with 11 sessions, the treatment activities and the adaptive responses of the subject were measured as outcome of the SI treatment. The goal of sessions were measured as Goal Attainment Scale, and re-evaluation was done on December in 2012. Results : During SI treatment, the subject was improved the stability of proximal body parts so that maintained Supine-Flexion Posture more than 20 seconds. He also showed increased attention span continuously about 1 activity on physical play. Conclusion : According to the results of this study, it was verified that sensory integrative intervention has positive effective on postural control and occupational performance (play) of the preschooler with postural disorder.

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Endobronchial Metastasis of Extrapulmonary Malignancies (폐외 악성 종양의 기관지내 전이)

  • Kim, Do-Hoon;Park, Moo-Suk;Chung, Jae-Ho;Cheong, Jae-Hee;Kim, Se-Kyu;Chang, Joon;Kim, Sung-Kyu;Kim, Young-Sam
    • Tuberculosis and Respiratory Diseases
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    • v.53 no.3
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    • pp.285-293
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    • 2002
  • Background : The lung is the most common site for a metastasis of extrapulmonary malignant tumors. however, reports on an endobronchial metastasis are rare. An endobronchial metastasis is defined as a documented extrapulmonary neoplasms metastatic to the segmental or more proximal central bronchus within a bronchoscopically visible range. The purpose of this study was to define the clinical characteristics of an endobronchial metastasis of extrapulmonary malignancies. Materials and Methods : The clinical features and treatment outcomes of 27 endobronchial metastatic cancer cases were reviewed from June, 1991 to May, 2001 in the Severance Hospital. Results : The patients' age ranged from 18 to 75. There were 17 men and 10 women. The primary tumors included the colorectum in 7, the uterine cervix in 4, the stomach and the breast in 3 patients each, and an osteosarcoma in 2 patients. The main complaint of most patients was coughing and a chest X-ray revealed a hilar mass, a parenchymal, and an atelectasis. The mean recurrence interval time was 45.5 months. The median and mean survival times were 10 and 12.3 months, respectively. Conclusion : An endobronchial metastasis is an ominous finding, and is associated with advanced-stage diseases. It requires differential diagnosis with a primary bronchogenic carcinoma. If atypical clinical features are present or an atypical cell type is discovered by a biopsy of the lesion in the lung mass, the appropriate diagnostic studies should be undertaken.

Prestenotic Bronchial Radioaerosol Deposition: A New Lung Scan Sign of Bronchial Obstruction (기관지 협착 근위부의 연무 침착: 폐스캔에서 기관지 폐색의 특이한 지표)

  • Chung, Soo-Kyo;Kim, Hak-Hee;Choi, Byung-Gil;Lee, Sang-Hoon;Kang, Si-Won;Bahk, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.3
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    • pp.307-312
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    • 1995
  • The present study has been carried out to assess the diagnostic usefulness of radioaerosol lung scan in complete bronchial obstruction (n=7) and bronchial narrowing (n=1) of varying causes. $^{99m}Tc$-phytate lung scan was performed using the aerosol generated by a BARC nebulizer. Scan alterations were correlated with those of chest radiography, bronchography, lung CT and/or brochoscopy. In every case scan showed characteristic intense deposition of radioaerosol in a short slightly dilated, bronchial segment immediately proximal to obstruction or stenosis. Characteristically it was accompanied by an airspace aerosol deposition defect distally. The finding of a short, clubbed, bronchial radioaerosol deposition with distal airspace defect is a sensitive, specific indicator of bronchial obstruction or stenosis. It was especially useful in the detection of the obstruction of a small bronchus at the lobar and sublobar levels. We propose to name it the prestenotic aerosol deposition sign.

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Comparison of arch form between Koreans and Egyptians (한국인과 이집트인의 치열궁 형태 비교)

  • Jang, Kab-Soo;Suk, Kyung-Eun;Bayome, Mohamed;Kim, Yoon-Ji;Kim, Seong-Hun;Kook, Yoon-Ah
    • The korean journal of orthodontics
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    • v.40 no.5
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    • pp.334-341
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    • 2010
  • Objective: The purpose of this study was to evaluate morphologic differences in the mandibular arch between Egyptian and Korean subjects. Methods: The Egyptian sample consisted of 94 mandibular casts (35 Class I, 32 Class II and 27 Class III). The Korean sample consisted of 462 mandibular casts (114 Class I, 119 Class II, and 135 Class III). The most facial portion of 13 proximal contact areas was digitized from photocopied images of the mandibular dental arches. Clinical bracket points were calculated for each tooth. The subjects were grouped according to arch form to compare the frequency distribution of the 3 arch forms between the ethnic groups in each Angle classification. Results: Egyptians had significantly narrower intermolar and intercanine widths ($p$ < 0.001), and shallower intermolar and intercanine depths ($p$ < 0.001) than Koreans. There was an even frequency distribution of the 3 arch forms within the Egyptian group ($p$ = 0.46). However, in the Korean group, the most frequent arch form was the square arch form (46.7%), while the frequency of the tapered arch form was significantly lower (18.8%). Conclusions: These results might provide helpful information in evaluating morphologic differences between ethnic groups in selection of preformed superelastic archwires.

Comparison of model analysis measurements among plaster model, laser scan digital model, and cone beam CT image (석고 모형, 레이저 스캔 디지털 모형, 콘 빔 CT 영상 간의 모형 분석 계측치 비교)

  • Lim, Mi-Young;Lim, Sung-Hoon
    • The korean journal of orthodontics
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    • v.39 no.1
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    • pp.6-17
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    • 2009
  • Objective: The purpose of this study was to evaluate the possibility of using a digital model and cone beam computed tomograph(CBCT) image for model analysis. Methods: Model analyses of CBCT images, plaster models, and digital models of 20 orthodontic patients with a permanent dentition with no proximal metal restorations, were compared. Results: The average differences of tooth size measurements were 0.01 to 0.20 mm, and the average difference of arch length discrepancy measurements were 0.41 mm in the maxilla and 0.82 mm in the mandible. The difference in Bolton discrepancy measurements was 0.17 mm for the anterior region and 0.44 mm overall but with no statistically significant difference. When comparing CBCT images with plaster models, the average differences in tooth size measurements were -0.22 to 0.01 mm, and the average differences in arch length discrepancy measurements were 0.43 mm in the maxilla and 0.32 mm in the mandible. Difference in Bolton discrepancy measurements were 0.35 mm in the anterior region and 1.25 mm overall. CBCT images showed significantly smaller overall Bolton discrepancy measurements. Conclusions: Although there were statistically significant differences in some model analysis measurements, the ranges of measurement errors of the digital model and CBCT images were clinically acceptable. Therefore, a digital model and CBCT image can be used for model analysis.

The Efficacy of Conjugated Linoleic Acid and Carprofen in Progression of Early Stage of Experimentally Induced Osteoarthritis in Dogs (개에서 Conjugated Linoleic Acid와 Carprofen이 실험적 골관절염 초기 진행에 미치는 효능)

  • Park, Se-il;Bae, Jae-sung;Kwon, Young-sam;Jang, Hwan-soo;Li, Wen-xue;Lim, Jae-hyun;Eom, Ki-dong;Kim, Jung-eun;Jang, Kwang-ho
    • Journal of Veterinary Clinics
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    • v.20 no.3
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    • pp.278-285
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    • 2003
  • This study was performed to compare early stage changes following the administrations of Conjugated Linoleic Acid (CLA), Carprofen and their combinations in the experimental canine cranial cruciate ligament rupture. Twenty five mongrel dogs were divided into five groups; Groups 1, 2, and 3 received a sectioning the cranial cruciate ligament (CCL) of the right stifle joint, and were administered CLA (250 mg/kg/day/orally), carprofen (4.4 mg/kg/day/orally), and their combinations for 4 weeks beginning 4 weeks postsurgery, respectively. Group 4 received sectioning CCL and no treatment. Group 5 was composed of unoperated normal dogs. The macroscopic observation of cartilage erosions on both the condyles and plateaus were evaluated, and the severity of the cartilage lesions and synovial inflammation was examined histologically at eight weeks after surgery. Histological examinations including hematoxylin and eosin stain, standard toluidine blue method, PAS technique and Masson trichrome technique, hematologic and radiographic evaluation were perfonned after experimental surgery. Slight yellowish discoloration of the surface was found in some of the experimental dogs. However macroscopic findings showed no significant differences among the groups. In radiographic findings, cranial displacement of the proximal tibia relative to the femoral condyles in all groups was observed but no significant differences among the groups was seen. This study showed that oral administration of CLA, carprofen and their combinations revealed no early stage change in the canine stifle joint following experimental rupture of the cranial cruciate ligament.