• Title/Summary/Keyword: pre-impact

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Community-Based Health Education and Communication Model Development for Opisthorchiasis Prevention in a High Risk Area, Khon Kaen Province, Thailand

  • Promthet, Paitoon;Kessomboon, Pattapong;Promthet, Supannee
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7789-7794
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    • 2015
  • Background: This study aimed to evaluate the impact of a community-based health education and communication programme on reducing liver fluke infections caused by the consumption of uncooked fish among people in a high-risk area of Thailand. Materials and Methods: The study was quasi-experimental in nature, with three-stages. Stage 1 involved a situational and capacity analysis of designated communities in Khon Kaen province. This was followed by the development of a model for community-based health education and communication to prevent liver fluke infections among high-risk people, and, lastly, implementation and evaluation of the model were performed. Data were collected using both qualitative and quantitative methods. In total, 390 people were surveyed, and quasi-experimental and comparison groups, each with 90 people, were assessed between May 2011 and April 2012. Analysis was using statistical OR, 95 % CI, the Willcoxon matched pairs signed ranks test, the chi-square test, and the Mann-Whitney U test. Results: The findings showed that most respondents had a high level of knowledge and understanding of liver fluke disease (89.5%, 95% CI:86.0-92.4), and positive attitudes toward the prevention of the disease (94.4%, 95% CI:91.6-96.4). However, with regard to changes in consumption of uncooked fish, most respondents were still in the pre-contemplation phase (55.1%, 95% CI:50.0-60.1), followed by the contemplation phase, 22.6%. Furthermore, four factors were found to be associated with the consumption of uncooked fish - the consumption of alcohol (OR 4.16, 95% CI:1.79-9.65), gender (OR 3.17, 95% CI:1.53-6.54), smoking (OR 3.03, 95% CI:1.31-7.05), and age 40 years and above (OR 2.68, 95% CI:1.02-7.05). After nine months of the health education and communication programme using local media based on local wisdom, culture and persons, the results showed that, compared to the control group, members of the experimental group had a higher level of knowledge, a better attitude and lower levels of ill-advised consumption behaviour. Also, it was found that consumption of uncooked fish, by an assessment of the level of stage of change, was reduced. (p-value 0.002). Conclusions: The health education and communication programme developed as part of the study was effective in changing the consumption of uncooked fish. Therefore, this approach should be promoted in other high-risk areas in Thailand in the future.

Clinical Practice of Blood Transfusion in Orthotopic Organ Transplantation: A Single Institution Experience

  • Tsai, Huang-Wen;Hsieh, Fu-Chien;Chang, Chih-Chun;Su, Ming-Jang;Chu, Fang-Yeh;Chen, Kuo-Hsin;Jeng, Kuo-Shyang;Chen, Yun
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.8009-8013
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    • 2015
  • Background: Orthotopic organ transplantation, a treatment option for irreversible organ dysfunction according to organ failure, severe damaged organ or malignancy in situ, was usually accompanied with massive blood loss thus transfusion was required. We aimed to evaluate the adverse impact of blood transfusion on solid organ transplantation. Materials and Methods: From January, 2009 to December, 2014, patients who received orthotopic organ transplantation at Far Eastern Memorial Hospital medical center were enrolled. Clinical data regarding anemia status and red blood cell (RBC) transfusion before, during and after operation, as well as patient outcomes were collected for further univariate analysis. Results: A total of 105 patients who underwent orthotopic transplantation, including liver, kidney and small intestine were registered. The mean hemoglobin (Hb) level upon admission and before operation were $11.6{\pm}1.8g/dL$ and $11.7{\pm}1.7g/dL$, respectively; and the nadir Hb level post operation and the final Hb level before discharge were $8.3{\pm}1.6g/dL$ and $10.2{\pm}1.6g/dL$, respectively. The median units (interquartile range) of RBC transfusion in pre-operative, peri-operative and post-operative periods were 0 (0-0), 2 (0-12), and 2 (0-6) units, respectively. Furthermore, the median (interquartile range) length of hospital stay (LHS) from admission to discharge and from operation to discharge were 28 (17-44) and 24 (16-37) days, respectively. Both peri-operative and post-operative RBC transfusion were associated with longer LHS from admission to discharge and from operation to discharge. Furthermore, it increased the risk of post-operative septicemia. While peri-operative RBC transfusion elevated the risk of acute graft rejection in patients who received orthotopic transplantation. Conclusions: Worse outcome could be anticipated in those who had received massive RBC transfusion in transplantation operation. Hence, peri-operative RBC transfusion should be avoided as much as possible.

Preanalytical Stability of Adrenocorticotropic Hormone Depends on Time to Centrifugation (전혈에서 시간과 온도에 따른 Adrenocorticotropic Hormone의 안정성 평가)

  • Shin, Sun-Young;Lee, Hyun-Joo;Min, Gyung-Sun;Lee, Ho-Young
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.1
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    • pp.116-119
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    • 2009
  • Background: Preanalytical factors can affect reliability of hormone assay results. Adrenocorticotropic hormone (ACTH) in blood is considered highly unstable because of proteolytic degradation, so storage of blood samples on ice until analysis is recommended. In clinical practice, however, this procedure may present logistical problems because most samples for ACTH measurement must be shipped from the place of sample collection to the laboratory. Therefore, we studied the impact of time and temperature before plasma separation and analysis on the results of ACTH assays. Methods: A total number of 22 patients were enrolled in this study. We obtained 2 blood samples. ACTH concentrations were 35~126 pg/mL. ACTH concentrations were measured by immunoradiometric assay (IRMA) using commercial kits (CIS Biointernational, Gif-sur-Yvette, France). Results: ACTH levels showed a significant difference between the samples of $22^{\circ}C$ EDTA and $4^{\circ}C$ EDTA. Measured ACTH concentrations significantly decreased with time before freezing at $-20^{\circ}C$. ACTH levels showed no significant difference between the groups of after storage for 24 hr without centrifugation at $22^{\circ}C$ and $4^{\circ}C$. Conclusion: We recommend that blood samples be obtained on pre-chilled EDTA collection tubes. The shortest possible time between sample collection and processing is always the best laboratory practice.

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A Study on Experimental Vibration pre-estimation Techniques of Structure (구조물의 실험적 진동예측 기술에 관한 연구)

  • 이홍기;권형오
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1992.10a
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    • pp.48-52
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    • 1992
  • 진동원을 가진 장비를 임의의 구조물에 설치할 경우 관심이 되는 문제는 구 조물의 임의의 위치에서의 진동 수준을 추정하는 일이다. 특히 정밀장비를 다루는 반도체 공장에서 크린룸이나, 정밀측정, 분석 실험실등 미진동을 제 어해야 하는 분야에서는 더욱 그 필요성이 대두되고 있다. 진동제어가 필요 한 공간에 대한 진동수준의 예측이 가능할 경우 진동윈이나 수진점(active and passive type)방진에서 최적화된 전달률(transmissibility)을 명확히 결정 할 수 있어 설계와 시행오차를 최소화 할 수 있다. 그러나 이러한 실제문제 를 다룰 경우 대부분 진동제어 구조물은 복잡하고 설치 운용되는 장비들은 대형, 복합장비가 사용되는 것이 일반적이고 수행기간도 여러가지 공정상 단 시간에 이루어져야 하는 현실적인 어려움이 있다. 진동제어가 필요한 구조물 에 대한 임의의 공간에서 진동수준을 신속하고 정확하게 예측하기 위해서는 최소한 두 가지 정보만이라도 명확히 해야 한다. 하나는 장비의 주파수별 정 확한 가진력의 산정이고 다른 하나는 장비가 설치되고 진동제어가 필요한 구조물에 대한 동적특성(dynamic property)이다. 가진력에 대한 정보는 일반 적으로 장비제작사가 제시하는 것이 원칙이나 그렇지 못할 경우 구조해석 기술자(structure engineer)가 해석적으로 추정하거나 또는 명확히 가진 특성 을 알지 못하는 복잡한 장비는 실험적으로 결정해야 한다. 구조물의 동적 특 성을 나타내는 모빌리티(mobility)를 구하는 방법은 해석적인 방법과 실험적 인 방법이 있으나 복합재료, 복잡한 구조형태나, 지지조건, 다양한 결합부의 동적 특성을 정의하여 해석적으로 정확히 해결하기에는 어려움이 있다. 이러 한 제한조건을 손쉽게 해결하는 방법은 실 구조물에 대한 동적실험(dynamic test)을 통하여 단기간에 동적특성을 결정하고 SDM(structure dynamic modification)이나 FRS(force response simulation)를 수행하여 임의의 좌표 공간에 대한 진동수준을 해석적으로 예측할 뿐만 아니라 구조물의 진동제어 를 위한 동적인자를 변경시킬 수 있는 정보를 제공하며 장비를 방진할 경우 신뢰성 있는 전달률을 결정할 수 있다. 실험적으로 철교, 교량이나 건물의 철골구조 및 2층 바닥 등 대,중형의 복잡한 구조물에 대항 동특성을 나타내 는 모빌리티를 결정할 경우 충격 가진 실험이 사용되는 실험장비 측면에서 나 실험을 수행하는 과정이 대체적으로 간편하다. 그러나 이 경우 대상 구조 물을 충분히 가진시킬수 있는 용량의 대형 충격기(large impact hammer)가 필요하게 된다. 이러한 동적실험은 약 길이 61m, 폭 16m의 4경간 교량에 대 하여 동적실험을 수행하여 가능성을 확인하였다. 여기서는 실험실 수준의 평 판모델을 제작하고 실제 현장에서 이루어질 수 있는 진동제어 구조물에 대 한 동적실험 및 FRS를 수행하는 과정과 동일하게 따름으로써 실제 발생할 수 있는 오차나 error를 실험실내의 차원에서 파악하여 진동원을 있는 구조 물에 대한 진동제어기술을 보유하고자 한다.

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A Multi-Wavelength Study of Galaxy Transition in Different Environments (다파장 관측 자료를 이용한 다양한 환경에서의 은하 진화 연구)

  • Lee, Gwang-Ho
    • The Bulletin of The Korean Astronomical Society
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    • v.43 no.1
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    • pp.34.2-35
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    • 2018
  • Galaxy transition from star-forming to quiescent, accompanied with morphology transformation, is one of the key unresolved issues in extragalactic astronomy. Although several environmental mechanisms have been proposed, a deeper understanding of the impact of environment on galaxy transition still requires much exploration. My Ph.D. thesis focuses on which environmental mechanisms are primarily responsible for galaxy transition in different environments and looks at what happens during the transition phase using multi-wavelength photometric/spectroscopic data, from UV to mid-infrared (MIR), derived from several large surveys (GALEX, SDSS, and WISE) and our GMOS-North IFU observations. Our multi-wavelength approach provides new insights into the *late* stages of galaxy transition with a definition of the MIR green valley different from the optical green valley. I will present highlights from three areas in my thesis. First, through an in-depth study of environmental dependence of various properties of galaxies in a nearby supercluster A2199 (Lee et al. 2015), we found that the star formation of galaxies is quenched before the galaxies enter the MIR green valley, which is driven mainly by strangulation. Then, the morphological transformation from late- to early-type galaxies occurs in the MIR green valley. The main environmental mechanisms for the morphological transformation are galaxy-galaxy mergers and interactions that are likely to happen in high-density regions such as galaxy groups/clusters. After the transformation, early-type MIR green valley galaxies keep the memory of their last star formation for several Gyr until they move on to the next stage for completely quiescent galaxies. Second, compact groups (CGs) of galaxies are the most favorable environments for galaxy interactions. We studied MIR properties of galaxies in CGs and their environmental dependence (Lee et al. 2017), using a sample of 670 CGs identified using a friends-of-friends algorithms. We found that MIR [3.4]-[12] colors of CG galaxies are, on average, bluer than those of cluster galaxies. As CGs are located in denser regions, they tend to have larger early-type galaxy fractions and bluer MIR color galaxies. These trends can also be seen for neighboring galaxies around CGs. However, CG members always have larger early-type fractions and bluer MIR colors than their neighboring galaxies. These results suggest that galaxy evolution is faster in CGs than in other environments and that CGs are likely to be the best place for pre-processing. Third, post-starburst galaxies (PSBs) are an ideal laboratory to investigate the details of the transition phase. Their spectra reveal a phase of vigorous star formation activity, which is abruptly ended within the last 1 Gyr. Numerical simulations predict that the starburst, and thus the current A-type stellar population, should be localized within the galaxy's center (< kpc). Yet our GMOS IFU observations show otherwise; all five PSBs in our sample have Hdelta absorption line profiles that extend well beyond the central kpc. Most interestingly, we found a negative correlation between the Hdelta gradient slopes and the fractions of the stellar mass produced during the starburst, suggesting that stronger starbursts are more centrally-concentrated. I will discuss the results in relation with the origin of PSBs.

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Study Protocol for the Most Effective Recall Method in a Cervical Cancer Screening Program in Klang, Malaysia

  • Rashid, Rima Marhayu Abdul;Dahlui, Maznah
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5867-5870
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    • 2013
  • Background: Cervical cancer is the second most common cancer among Malaysian women with an ASR of 17.9 and a mortality rate of 5.6 per 100,000 population in 2008 (GLOBOCAN, 2008). The 5 year prevalence was estimated to be 14.5 per 100,000 population. As the second most common cancer affecting productive females, cervical cancer imposes an impact to the socioeconomic aspect of the country. However, the poor uptake of cervical cancer screening is a major problem in detecting early pre-cancerous lesions and thus, delay in initiating treatment for cervical cancer. Realizing the urgency to increase the uptake of PAP smear, besides enhancing the promotion of PAP smear screening for women above 35 years old, the call-recall system for pap smear screening had been piloted in one of the suburban districts which aimed to improve regular participation of women for cervical and breast cancer screening. This is of public health importance as identifying the best feasible option to increase patient's respond to participate in the screening program effectively in our setting will be helpful in implementing an organized regular population based screening program tailored to our setting. The pilot program of cervical cancer screening in Klang was an opportunity to assess different options in recalling patients for a repeat pap smear to increase their participation and adherence to the program. Methods and Results: This was a population based randomized control trial. Women aged 20-65 years in the population that matched the inclusion and exclusion criteria were re-called for a repeat smear. There are four different intervention groups; letter, registered letters, short messages services (SMS) and phone calls where 250 subjects were recruited into each group. Samples were generated randomly from the same population in Klang into four different groups. The first group received a recall letter for a repeat smear similar to the one that has been given during the first invitation. The intervention groups were either be given a registered letter, an SMS or a phone call to re-call them. The socio-demographic data of the patients who came for uptake were collected for further analysis. All the groups were followed up after 8 weeks to assess their compliance to the recall. Conclusions: The study will provide recommendations about the most effective methods for recall in a population based pap smear screening program on two outcomes: i) patients response; ii) uptake for repeat pap smear.

Wheel tread defect detection for high-speed trains using FBG-based online monitoring techniques

  • Liu, Xiao-Zhou;Ni, Yi-Qing
    • Smart Structures and Systems
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    • v.21 no.5
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    • pp.687-694
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    • 2018
  • The problem of wheel tread defects has become a major challenge for the health management of high-speed rail as a wheel defect with small radius deviation may suffice to give rise to severe damage on both the train bogie components and the track structure when a train runs at high speeds. It is thus highly desirable to detect the defects soon after their occurrences and then conduct wheel turning for the defective wheelsets. Online wheel condition monitoring using wheel impact load detector (WILD) can be an effective solution, since it can assess the wheel condition and detect potential defects during train passage. This study aims to develop an FBG-based track-side wheel condition monitoring method for the detection of wheel tread defects. The track-side sensing system uses two FBG strain gauge arrays mounted on the rail foot, measuring the dynamic strains of the paired rails excited by passing wheelsets. Each FBG array has a length of about 3 m, slightly longer than the wheel circumference to ensure a full coverage for the detection of any potential defect on the tread. A defect detection algorithm is developed for using the online-monitored rail responses to identify the potential wheel tread defects. This algorithm consists of three steps: 1) strain data pre-processing by using a data smoothing technique to remove the trends; 2) diagnosis of novel responses by outlier analysis for the normalized data; and 3) local defect identification by a refined analysis on the novel responses extracted in Step 2. To verify the proposed method, a field test was conducted using a test train incorporating defective wheels. The train ran at different speeds on an instrumented track with the purpose of wheel condition monitoring. By using the proposed method to process the monitoring data, all the defects were identified and the results agreed well with those from the static inspection of the wheelsets in the depot. A comparison is also drawn for the detection accuracy under different running speeds of the test train, and the results show that the proposed method can achieve a satisfactory accuracy in wheel defect detection when the train runs at a speed higher than 30 kph. Some minor defects with a depth of 0.05 mm~0.06 mm are also successfully detected.

A Study on the Importance and order of priority of the Major control item for DMSMS by using AHP analysis (AHP 분석을 통한 부품단종 주요관리항목 중요도 및 우선순위에 관한 연구)

  • Moon, Jayoung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.48-54
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    • 2020
  • DMSMS (Diminishing Manufacturing Sources and Material Shortage) is increased by developing the scientific technique and downsizing the military part market. DMSMS affects the increase in total life cycle costs and serviceability. Therefore, advance control for parts is important to reduce the cost, and a database is needed to share information on the DMSMS. A task needs to be performed continuously by setting the major control item to management more efficiently. The purpose of this study was to deduce the major control item for the DMSMS management system. Thus, the pre-control item basis of the DAPA (Defense Acquisition Program Administration) Manual and the SD-22 Manual were first selected, and the results of the survey were analyzed by AHP (Analytic Hierarchy Process) method. Fifteen of the detailed items were stratified into three criteria (Impact, Probability, and cost of the DMSMS), and each weight for the items was calculated using a nine-point scale survey. The AHP survey was executed with 25 specialists in the DMSMS management field, and the score of consistency ratio over 0.1 was excluded. The model explained the results and suggested future directions for development.

Recognition Method of Korean Abnormal Language for Spam Mail Filtering (스팸메일 필터링을 위한 한글 변칙어 인식 방법)

  • Ahn, Hee-Kook;Han, Uk-Pyo;Shin, Seung-Ho;Yang, Dong-Il;Roh, Hee-Young
    • Journal of Advanced Navigation Technology
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    • v.15 no.2
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    • pp.287-297
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    • 2011
  • As electronic mails are being widely used for facility and speedness of information communication, as the amount of spam mails which have malice and advertisement increase and cause lots of social and economic problem. A number of approaches have been proposed to alleviate the impact of spam. These approaches can be categorized into pre-acceptance and post-acceptance methods. Post-acceptance methods include bayesian filters, collaborative filtering and e-mail prioritization which are based on words or sentances. But, spammers are changing those characteristics and sending to avoid filtering system. In the case of Korean, the abnormal usages can be much more than other languages because syllable is composed of chosung, jungsung, and jongsung. Existing formal expressions and learning algorithms have the limits to meet with those changes promptly and efficiently. So, we present an methods for recognizing Korean abnormal language(Koral) to improve accuracy and efficiency of filtering system. The method is based on syllabic than word and Smith-waterman algorithm. Through the experiment on filter keyword and e-mail extracted from mail server, we confirmed that Koral is recognized exactly according to similarity level. The required time and space costs are within the permitted limit.

The Effect of Hope-entrepreneur's Entrepreneurial Environment and Characteristics of Start-up Preparation on a Start-up Intention (희망창업자의 창업환경과 창업준비 특성이 창업의도에 미치는 영향)

  • Kim, Hye Wha;Byun, Sang Hae
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.13 no.5
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    • pp.17-28
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    • 2018
  • This study examined which influence the entrepreneurial environment and charateristics of start-up preparation have upon a start-up intention. For the purpose of offering useful data so that the hope-entrepreneurs of planning start-up can do more successful start-up through this, it carried out questionnaire from June 13, 2018 to July 14, 2018 targeting employee are located in K region. As a result, excluding 6 copies with a difficulty in the application to statistics among totally 205 copies, 199 copies were chosen as the final samples. Data were conducted reliability analysis, factor analysis, correlation analysis and regression analysis by using SPSS 23.0. The results are as follows. First, the entrepreneurial environment had a significant impact on a start-up intention. Second, the start-up preparation level had a significant effect on a start-up intention. However, this study limited the sampling region to A area, thereby having a limitation in generalizing the findings all over the country. Moreover, there is a suggestion that a continuous research will need to be performed in terms of an influential factor in pre-entrepreneurs' start-up intention as well as in entrepreneurial environment and start-up preparation level.