• Title/Summary/Keyword: physical resource

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Use of Fast Transfer Analysis Cartridges for Cervical Sampling and Real Time PCR Based High Risk HPV Testing in Cervical Cancer Prevention - a Feasibility Study from South India

  • Vijayalakshmi, Ramshankar;Viveka, Thangaraj Soundara;Malliga, JS;Murugan, Kothandaraman;Kanchana, Albert;Arvind, Krishnamurthy
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5993-5999
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    • 2015
  • Background: Molecular testing for human papillomavirus (HPV) is the most objective and reproducible of all cervical cancer screening tests and also less demanding in terms of training and quality assurance. However, there is an impending need for cost effective molecular HPV testing methods with sampling ease, easy storage measures and minimum turn around times suitable for a low resource setting. Objective : Our aim was to evaluate the feasibility of using a fast transfer analysis (FTA) mini elute cartridge for cervical sampling to identify high risk HPV by real time PCR and to compare molecular HPV testing and Pap cytology testing to predict histologically confirmed cervical precancer (CIN 2+ lesions) in a cervical cancer prevention program. Materials and Methods: This was conducted as a pilot study (n=200) on women sampled using FTA mini elute cartridges, genotyped by two different real time PCR assays, detecting 13 high risk HPV (HR HPV) species, including HPV16 along with its physical DNA status. Results obtained from each of the tests were compared and analysed using suitable statistical tests. Results: With FTA mini elute cartridge samples HR HPV positivity was seen in 48/200 (24%). Of these, presence of HPV 16 DNA was observed in 28/48 (58.3%) women. High risk HPV was positive in 20% (37/185) of women with benign cytology and 73.3% (11/15) of women with abnormal cytology findings. A very significant correlation (${\chi}^2=22.090$ ; p=0.000) was observed between cytology and HR HPV findings showing an increasing trend of HR HPV prevalence in 50% (1/2) of LSIL, 75% (3/4) of HSIL and 100% (3/3) of SCC. Of the CIN 2+ lesions identified by histopathology, 88.9% (8/9) had HR HPV. A significant association (${\chi}^2=11.223$ ; p=0.001) of HR HPV and histopathologically confirmed CIN 2+ lesions was found. Sensitivity of the two tests were comparable but specificity of Pap testing was better (90.7% vs 70.4%) to predict histopathologically diagnosed cervical precancers. Conclusions: The current study explored the feasibility of using a FTA mini elute cartridge for cervical sampling for the first time in India as a part of a community based cervical cancer prevention program. We suggest that FTA based sampling is suitable and feasible for real time based HPV testing. Molecular HR HPV testing can be more sensitive and useful to identify high risk women requiring Pap testing which is more specific to detect histologically confirmed cervical precancer.

A Study on Information Users' Needs and Information Seeking Behavior of Doctoral Researchers in Digital Age (디지털 환경에서 학술연구자들의 정보요구 및 이용행태에 관한 연구 - 인문사회분야와 과학기술분야의 비교를 중심으로 -)

  • Kim, Jeong-Hwan;Kim, Jay-Hoon;Hwang, Jae-Young
    • Journal of Korean Library and Information Science Society
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    • v.42 no.3
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    • pp.189-208
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    • 2011
  • In the digital environment where the Internet and IT change rapidly, researchers have utilized scientific information by relying on more complex and various media than before. This study performed a group interview with thirteen questions derived from five categories in order to understand information needs and information seeking behaviors of Korean doctoral researchers in this information environment. The five categories are (1) identifying information resource usage pattern, (2) attitude towards information resources and reasons for use, (3) IT skills and information literacy, (4) physical library use vs electronic access, and (5) attitudes toward the digital library. In particular, this study focused on analyzing similarities and differences of two groups of researchers selected equally in the humanities and social sciences and in science and technology by doing the interview. The research showed that there are no differences in the goal of using scientific information, information literacy, the ratio of using written materials to electronic resources, and routes of acquiring research ideas or knowledge, but there are differences in materials used for studies or researches and in favorite scientific portal sites.

Trends of Technology Development through Investigation and Analysis of Domestic Patent Related to Wastewater Treatment Technology including Membrane, Sludge Treatment and Advanced Treatment Technology and Equipment (분리막 및 슬러지 처리와 고도처리 기술·장비를 포함한 하·폐수 처리기술의 특허 조사·분석을 통한 기술개발 동향)

  • Yoo, Ho Sik;Kim, Ji Tae
    • Membrane Journal
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    • v.27 no.5
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    • pp.375-388
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    • 2017
  • Wastewater treatment (WWT) technology has been developing from simple pollutant treatment to energy and resource-saving advanced technology, and various technologies combined with IT and BT are developed to minimize the amount of pollutant and toxic substance discharge to the public water areas and to improve operational efficiency. To examine the development trend of domestic wastewater treatment technology, the registered patent technologies were surveyed, classified and analyzed by year and sector. This paper considers the status of patent registration related to WWT from 2010.1 to 2017.5 in terms of the number of specific technical areas, and the trends are analyzed based on the 10 categorization field such as biological and physicochemical treatment process, equipment and device, material, sludge treatment, membrane, process control and 42 specific technical areas. A total of 3,356 patents have been registered since 2010, and the number of patents has been decreasing since the peak at 2013 and maintains 3~400 per year. The total number of patents has not yet been less than other countries, but the number of patents of more advanced technologies, which can lead the global market, such as process monitoring, new concept processing and equipment technologies is still insufficient compared to developed countries.

Active and Cognitive Evaluating of the Recreational Spaces in Natural Settings (자연휴양공간(自然休養空間)의 이용행동(利用行動) 및 인지적(認知的) 평가(評價))

  • Kim, Bum Soo;Chung, Yoon Soo
    • Journal of Korean Society of Forest Science
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    • v.83 no.4
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    • pp.429-440
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    • 1994
  • This study attempt to evaluate the recreation space(two patterns ; one is open space ; forest, water-front space and free open space, the other recreational fercilities) located in the natural area based on clarifying the relationship between the physical conditions of these spaces and human response(users' cognitive evaluation and users' activity pattern). On this standpoint it was proceeded to analyses of the information which was collected by interviews to users who were in this open space at the natural park of Osaka Prefecture. Through this study, the results were summarized as follows ; 1) Forest and waterfront space are considered to be a basic factor of the composition in natural recreation areas. There was difference on the recreational value depending on condition of forest composition. The hardwood-forest apparently high in its efficiency. 2) Free open space is a definite recreational space surely wide in its scope of active of recreational use. The site should be setted up considering the plants conditions around and geographical features according to the recreational activities, and the ground cover should be well controlled. 3) The recreational facilities in natural settings such as the sightseeing tower, the insect display hall, and the camp site appeared to produce low value as a recreational space. It was desirable that recreational activities be allowed within the scope. Consequently, we should carefully consider environmental capacity and landscape to designing these spaces 4) Traditional history and cultural properties are recognized as part of recreational resource as and also as essence of the compositions. So continuos care and proportion of history and cultural properties should be guaranteed.

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The Organizational Structure and Role of Smart City Governance (스마트시티 거버넌스의 조직체계와 역할)

  • Nam, Kwang-Woo;Park, Jeong-Woo;Park, Jun-Ho;Ji, Sang-Tae
    • Journal of the Korean Regional Science Association
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    • v.33 no.1
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    • pp.69-85
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    • 2017
  • The positive changes in urban space and urban activities resulting from the urban services provided by Smart City is not accomplished by simply creating the physical environment built on ICT but through the cooperation and participation of citizens and private sector, which is in fact key to success. In this study, this research analyzed the role and structure of smart governance, which is a system of horizontal cooperation between public and private sector, and analyze its role in developing Smart City. The study also proposes various ways to facilitate such development in each of critical categories. For this purpose, this research studied 228 smart services across 11 categories registered in the Ministry of Land and Transport in Korea to analyze the spatial distribution of smart services by spatial hierarchy and their characteristics Also, the research conducted a case study of MetroGIS, which is an information collaboration governance system for the greater area of Minneapolis and St. Paul in the state of Minnesota, United States, to explore how governance is formed; its organizational structure; the role of sub-level organization hierarchy and their interrelationship. The results of the analysis suggest that the following conditions are required to create a smart city: first, public sector resource assistance for building community; second, enhanced communication system within the community and with outside the community; securing financial stability and establishing a model of sustainable development to induce the community to evolve into a governance form.

Comparison of Surface and Air Temperature depending on Cover Materials in Playground (운동장의 피복 유형별 표면 및 대기온도 비교)

  • Lee, Hak Hyeong;Kwon, Oh Gyung;Shin, Jin He;Kabir, Faisal Md.;Lee, Kang Su;Ryu, Sungpil;Lee, Dong Woon
    • Weed & Turfgrass Science
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    • v.4 no.1
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    • pp.71-75
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    • 2015
  • Playground is frequently used for physical and sports activity by students as well as by common people, which is constructed with various cover materials on the ground. This research surveyed the surface temperature in Kyungpook National University Sangju campus playground which is covered with various cover materials [bare field, zoysiagrass (Zoysia japonica) turf field, urethane track, concrete field, epoxy field and artificial turf field] in Sangju, Gyeongsangbukdo, Korea. Temperature was measured 4 times per day at 09:00, 12:00, 15:00, and 18:00 from May to October 2014 in surface and 1 m height above the ground. Surface temperature was different, depending on cover materials and survey time. Bare field and zoysiagrass turf field was lower surface temperature than other sites. Higher surface temperature site was different depending on survey time. Urethane track and artificial turf field was hotter than other sites at 12 and 15 hours, however concrete and epoxy field was hot at 18 hours. One meter above ground temperature was the highest in artificial turf field except at 18 hours. So natural turf, zoysiagrass playground will increase the athletic performance by reduce the surface and above ground temperature.

Mycelial growth properties of an Amanita javanica strain under various culture conditions (노란달걀버섯 균주의 여러 환경 조건에 따른 균사 생장 특성)

  • Kang, Jung-A;Ka, Kang-Hyeon;Kim, Jun Young;Yoon, Seong-Tak;Kim, Seong Hwan
    • Journal of Mushroom
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    • v.17 no.4
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    • pp.191-196
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    • 2019
  • The edible ectomycorrhizal mushroom Amanita javanica is a valuable species protected by forest law in Korea. However, basic characterization data on its use as an important forest resource has been limited. This study was performed to determine mycelia growth characteristics of the domestically isolated Amanita javanica strain NIFoS 1267 on potato dextrose agar media under diverse culture conditions. Physical factors temperature, pH, and light, as well as chemical factors salts, heavy metals, and pesticides were examined for their effects on the growth of the mushroom strain. The mycelia of A. javanica strain exhibited optimal growth when cultured in dark at 30℃ in media with a pH of 5-6. Normal levels of growth were observed in media containing up to 2% saline. At a heavy metal ion content of 50 ppm, mycelial growth was not affected by arsenic ion but was affected by cadmium and lead ions. In the tests performed with two pesticides used in Korean forests, the growth of the mushroom strain was not affected by the presence of abamectin, but was inhibited in media containing acetamiprid, emamectin benzoate, or thiacloprid. These results are expected to facilitate artificial cultivation of A. javanica as a new commercial product.

Estimation of Net Radiation in Three Different Plant Functional Types in Korea (한국의 세 개의 다른 식생기능형태에서의 순복사 추정)

  • Kwon, Hyo-Jung
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.11 no.2
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    • pp.79-85
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    • 2009
  • Net radiation ($R_N$) is a driving force of biological and physical processes between the surface and the atmosphere and its knowledge is critical to weather forecasting and water resource management. The measurement of $R_N$ is, however, scarce and it is typically estimated from an empirical relationship. This study presented two different methods of $R_N$ estimation over three major plant functional types (i.e., a deciduous forest, a coniferous forest, and a farmland) in Korea. One is a linear regression method between $R_N$ and solar radiation and the other is a radiation balance method. The two methods were examined using the data collected in 2008 at the three sites. Based on the linear regression method over a year, $R_N$ was 70% of the incoming shortwave radiation ($R_S{\downarrow}$) for a deciduous forest, 79% for a coniferous forest, and 64% for a farmland, indicating that the relationship was plant functional type-specific. For the radiation balance method, the inclusion of longwave radiation component slightly improved $R_N$ estimations. Overall, there was a good agreement between the observed and the estimated $R_N$ from both methods, indicating a reliable applicability of the two methods in estimating $R_N$.

The Paradox of the Plankton (플랑크톤 패러독스)

  • Lee, Hak Young;Moon, Sung-Gi;Huh, Man-Kyu
    • Journal of Life Science
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    • v.25 no.5
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    • pp.601-606
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    • 2015
  • Hutchinson (1961) proposed that the large number of species in most plankton communities is remarkable in review of the competitive exclusion principle, which suggests that in homogeneous, well-mixed environments species that compete for the same resources cannot coexist. The principle of competitive exclusion would lead us to conclude that only a few species could coexist in such circumstances. Nevertheless, numerous competing species in most natural habitats are able to coexist, while generally only few resources (niches) limit these communities. It is coined “the paradox of plankton” by Hutchinson. We reviewed some literature of the proposed solutions and give a brief overview of the mechanisms proposed so far. The proposed mechanisms that we discuss mainly include spatial and temporal heterogeneity in physical and biological environment, externally imposed or self-generated spatial segregation, horizontal mesoscale turbulence of ocean characterized by coherent vortices, oscillation and chaos generated by several internal and external causes, stable coexistence and compensatory dynamic under fluctuating temperature in resource competition, and finally the role of toxin-producing phytoplankton in maintaining the coexistence and biodiversity of the overall plankton populations. Especially we sited Roy and Chattopadhyay’s reviews and their toxin-producing hypothesis by phytoplankton. This review may be some information to study plankton communities and effect to put the solutions to the paradox that have been proposed over the years into perspective.

Comparison of quality characteristics of Platycodon grandiflorum according to steaming and fermentation (증숙 및 발효에 따른 도라지의 품질특성 비교)

  • Kim, So-Young;Lee, Ye-Jin;Park, Dong-Sik;Kim, Haeng-Ran;Cho, Yong Sik
    • Food Science and Preservation
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    • v.22 no.6
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    • pp.851-858
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    • 2015
  • This study was designed to improve the sensory characteristics and mitigate the bitter taste of Platycodon gradiflorum. It was aimed at investigating the qualitative properties of fermented P. gradiflorum after repeated steaming and drying treatments. P. gradiflorum was heated for 2 hr at $95^{\circ}C$, being the first and third treatments compared afterwards. Lactobacillus plantarum, at a concentration of 10%, was used as starter culture. As a result, the third steaming process and the addition of starter improved the physical and chemical properties of P. gradiflorum i.e., crude saponin and total polyphenol contents increased significantly. Moreover, P. gradiflorum steamed three times and fermented by L. plantarum showed the higher overall preference score. Our results indicated that the three-time steaming and drying was an effective manufacturing process for the production of high-quality fermented P. gradiflorum. Lactic acid-fermented P. gradiflorum also could have a potential use as a valuable resource for the development of functional products.