• 제목/요약/키워드: physical evidence

검색결과 950건 처리시간 0.028초

The effect of fibroblast growth factor receptor inhibition on resistance exercise training-induced adaptation of bone and muscle quality in mice

  • Cho, Suhan;Lee, Hojun;Lee, Ho-Young;Kim, Sung Joon;Song, Wook
    • The Korean Journal of Physiology and Pharmacology
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    • 제26권3호
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    • pp.207-218
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    • 2022
  • Aging in mammals, including humans, is accompanied by loss of bone and muscular function and mass, characterized by osteoporosis and sarcopenia. Although resistance exercise training (RET) is considered an effective intervention, its effect is blunted in some elderly individuals. Fibroblast growth factor (FGF) and its receptor, FGFR, can modulate bone and muscle quality during aging and physical performance. To elucidate this possibility, the FGFR inhibitor NVP-BGJ398 was administrated to C57BL/6n mice for 8 weeks with or without RET. Treatment with NVPBGJ398 decreased grip strength, muscular endurance, running capacity and bone quality in the mice. FGFR inhibition elevated bone resorption and relevant gene expression, indicating altered bone formation and resorption. RET attenuated tibial bone resorption, accompanied by changes in the expression of relevant genes. However, RET did not overcome the detrimental effect of NVP-BGJ398 on muscular function. Taken together, these findings provide evidence that FGFR signaling may have a potential role in the maintenance of physical performance and quality of bone and muscles.

Aromatherapy Interventions for the Elderly: A Review of Research Trends and Methodologies in Korea

  • SunHwa Park;Mi-Hwa Kim;Mi-Seon Kim;Jin Lee
    • International Journal of Advanced Culture Technology
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    • 제11권4호
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    • pp.62-73
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    • 2023
  • This study aims to identify research trends and explore the latest methods of applying aromatherapy to the elderly. The main objective is to provide evidence in support of development of an aromatherapy nursing intervention program for the elderly. This investigation is in the form of a literature review focusing on the current status and trends in research conducted on aromatherapy intervention programs for the elderly in Korea over past decade. Published studies were identified through database such as KCI, RISS, DBpia, NDSL. A total 14 studies were selected for this review. The majority of selected articles fall within the field of nursing. The duration of the programs varied, ranging from less than 20 minutes to over 40 minutes, and consisted of 1 to 6 sessions. Most of methods involved massages using lavender oil in a hospital setting. Outcome variables were categorized into three main domains based on significance: psychological-emotional, interpersonal relationship, and physical-physiological. The variables within each category varied with 4 in psychological-emotional, 1 in interpersonal relationship, and 17 in physical-physiological. This review indicates that aromatherapy intervention programs have positive effects on the elderly and suggests the potential for developing similar interventions on a broader scale within community settings in the future.

과학수사지질학(Forensic Geology)의 출현: 새로운 지질학 영역의 구축 (Forensic Geology : New Pioneer in Geological Area)

  • 이옥선;김성용
    • 자원환경지질
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    • 제40권5호
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    • pp.705-711
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    • 2007
  • 우리가 생활하면서 부딪히는 수많은 판단들 속에서 특히 인간의 권리에 대한 사안은 민감하게 다루어진다. 특히 사실로 입증된 것만 인정하는 증거재환주의에 의해 물리적 증거의 확보 여부는 범죄수사과정에서 필수적임에 따라 과학수사의 중요성 및 수요는 증가하고 있다. 과학수사지질학은 지질학과 과학수사와의 융합 분야로, 과학수사를 위하여 지질학적 지식 및 기법을 바탕으로 물리적 증거를 비교 분석하여 범죄용의자와 범죄사건의 연관성을 파악함으로써 법정에서 유용한 자료로 활용된다. 1970년대 후반 과학수사지질학의 학문적 체계를 구축한 이래로 과학수사지질학의 연구대상은 암석, 광물, 토양, 퇴적물 등의 토양학적 증거에서 역사적 유물, 지뢰, 사체 등의 사회 문화적, 정치적, 군사적, 의학적 대상으로 확대되고 있다. 과학수사지질학의 역할이 단순 위치추적에서 고고학적 학설 증명, 역사적 사실 입증, 환경오염 원인 규명, 연대기적 식생 분포 및 인류학적 발생 규명 등으로 폭넓게 작용할 수 있음을 의미하고, 이는 발전된 지질학적 방법론을 적용할 수 있으며 다양한 과학수사지질학적 수요를 만족시킬 수 있다. 과학수사지질학의 연구 활동은 과학수사 전문기관을 중심으로 이루어지고 있으나, 우리나라 국립과학수사연구소의 과학수사 활동 분포에서 과학수사지질학적 비중은 극히 일부분으로 나타나고 있다. 따라서 전문 지질자원 연구기관을 중심으로 우리나라 지질학적 특성에 기반을 둔 연구방법 확보, 연구결과 활용사례 발굴 등 과학수사지질학의 역할 정립을 위한 체계적인 논의를 이끌어 낼 필요가 있다고 사료된다.

뇌졸중 후 요실금에 대한 침치료 임상진료지침 (Clinical Practice Guideline for acupuncture in Post-stroke urinary incontinence)

  • 이지원;신병철;이명수;임성민;유정희;조충식;문상관;육태한;주종천;이의주
    • 사상체질의학회지
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    • 제29권4호
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    • pp.317-325
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    • 2017
  • Objectives This study is aimed to develop a Clinical Practice Guideline (CPG) on acupuncture treatment for the stroke patients with Post-stroke Urinary Incontinence(PSUI). Methods Experts committee, consisting of stroke or methodology specialists, searched Medline, EMBASE, Cochrane Library, China National Knowledge Infrastructure, and 19 Korean medicine journals. The search terms were selected to screen the randomized controlled trials (RCTs) or systematic reviews for the effectiveness of acupuncture on PSUI, compared with placebo or conventional group. Levels of evidence and grades of recommendations were appraised based on Recommendations for Development of Clinical Practice Guideline in Korean Medicine. Results & Conclusions 8 RCT were included to build the CPG. There was a strong evidence to support the effectiveness of acupuncture treatment for PSUI. The moderate evidence was presented that over 3 times a week of the acupuncture should be performed over 4 weeks on the acupoints, such as BL23, CV3, SP6, CV4, CV6, ST28, BL28, BL32, GV20, BL22, GV4 or ST36, for 15-30 minutes. 1-150 Hz frequency is suggested if electro-acupuncture treatments is performed with. It was also suggested that the procedure should begin at the acute stage just after the vital signs of the patients are stabilized. There was a moderate evidence to support safety of acupuncture treatment for PSUI. We recommend acu-points of constitutional acupuncture for Sasangin on the healthy side.

치매환자의 보행에 관한 근거기반 중재에 대한 체계적 고찰 (Systematic Review of Evidence-Based Intervention for Gait in Dementia Patient)

  • 권애령;정해익
    • 한국콘텐츠학회논문지
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    • 제21권2호
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    • pp.667-675
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    • 2021
  • 본 연구는 치매환자의 보행의 중요성을 확인하고, 보행에 필요한 다양한 중재 방법의 필요성을 알리는데 의의를 두고자 근거 기반 중재에 대해 체계적 고찰을 실시하였다. PRISMA의 가이드라인과 근거 중심 중재를 바탕으로 체계적인 검토를 수행하였으며, 지난 10년간 국내 학술지에 게재 된 논문을 수집하고 중재 유형 및 보행과 함께 측정 된 종속 변수를 분석 하였다. 자료 검색은 RISS, KISS, 국립중앙 도서관, 국회 도서관을 통해 2011년 1월부터 2020년 6월까지의 연구 논문을 수집하였다. 주요 검색 용어는 '치매환자'와 '보행', '보행능력'이였다. 문헌 선택 기준에 해당하는 치매환자와 보행에 관한 57개의 논문을 검색하였으며, 그 중 2010년 이전의 논문과 중복된 논문, 종속변인이 보행 능력과 상관없는 논문을 제하고, 마지막으로 치매질환이 아닌 다른 질환의 환자를 대상으로 한 논문을 제하자 5권이 선정되었다. 보행의 중재종류는 낙상 예방, 신체 활동 등 운동과 관련된 프로그램이 많았으며, 보행과 함께 측정 된 종속 변수는 신체적, 심리적으로 다양했다. 치매환자를 위한 국내연구는 다각적인 방향과 방법으로 이루어지고 있지만, 신체적인 부분 중 하지부분의 기능향상과 보행에 관한 연구는 거의 전무하다. 따라서 치매환자의 보행에 관한 다각적이며, 다양한 중재 방법에 관한 연구가 필요하다.

장애 정도에 따른 공간적 포용성과 사회참여의 관계 (Relationship between Spatial Inclusivity and Social Participation According to Degree of Disability)

  • 김시화;박인권
    • 지역연구
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    • 제39권3호
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    • pp.65-83
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    • 2023
  • 본 연구에서는 신체의 불편함을 가진 사람들의 사회참여를 제고시키기 위해 '공간적 포용성'여 장애와 공간적 포용성이 사회참여에 미치는 영향을 실증적으로 규명하는 것을 목적으로 한다. 거주하는 지역의 사회·공간적 환경은 신체적 제약으로 인해 활동반경이 좁고 복합적인 장벽에 직면하는 장애인에게 매우 중요하다. 본 연구에서는 지역사회 내에서 장애인들이 비장애인들과 동등하게 관계를 형성하고 안전한 도시공간에서 기본적인 시설과 서비스로의 이용과 접근이 가능한 환경을 갖춘 것으로 장애인 관점의 공간적 포용성을 정의한다. 공간적 포용성은 개인의 관계망, 사회적 환경, 물리적 환경 등 세 가지 차원으로 구성되며, 물리적 환경은 거주 지역의 안전수준/자연환경/생활환경/대중교통 여건/의료서비스 여건 등을 포괄한다. 2019년 지역사회건강조사를 활용하여 장애 여부와 공간적 포용성에 따른 사회참여와의 관계를 2수준 다층회귀모형으로 분석한 결과는 다음과 같다. 첫째, 개인 수준의 개인적 관계망과 지역 수준의 물리적 환경이 사회참여에 미치는 긍정적 영향을 확인하였다. 둘째, 물리적 환경을 5개 하위요인으로 파악하였을 때 개별요소의 유의한 영향 관계는 확인할 수 없었다. 셋째, 지역 수준에서 신뢰할 수 있고 친근한 사회적 환경은 사회참여에 부적인 영향을 미치는 것으로 확인되었다. 이러한 분석 결과는 공간적 포용성이 장애인의 사회참여에 효과를 미치고 있음을 실증하고, 장애인의 사회참여 여건 마련 및 제고를 위한 도시계획 시사점을 제공한다.

Un-met Supportive Care Needs of Iranian Breast Cancer Patients

  • Abdollahzadeh, Farahnaz;Moradi, Narges;Pakpour, Vahid;Rahmani, Azad;Zamanzadeh, Vahid;Mohammadpoorasl, Asghar;Howard, Fuchsia
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권9호
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    • pp.3933-3938
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    • 2014
  • Background: Assessment of supportive needs is the requirement to plan any supportive care program for cancer patients. There is no evidence about supportive care needs of Iranian breast cancer patients. So, the aims of present study were to investigate this question and s predictive factors. Materials and Methods: A descriptive-correlational study was conducted, followed by logistic regression analyses. The Supportive Care Needs Survey was completed by 136 breast cancer patients residing in Iran following their initial treatment. This assessed needs in five domains: psychological, health system and information, physical and daily living, patient care and support, and sexuality. Results: Patient perceived needs were highest in the health systems and information (71%), and physical and daily living (68%) domains. Logistic regression modeling revealed that younger participants have more un-met needs in all domains and those with more children reported fewer un-met needs in patient care and support domains. In addition, married women had more un-met supportive care needs related to sexuality. Conclusions: The high rate of un-met supportive care needs in all domains suggests that supportive care services are desperately required for breast cancer patients in Iran. Moreover, services that address informational needs and physical and daily living needs ought to be the priority, with particular attention paid to younger women. Further research is clearly needed to fully understand supportive care needs in this cultural context.

Relationships of Musculoskeletal Disorder Symptoms and Perceived Workload among Hospital Workers

  • Ryu, Tae-Beum;Song, Joo-Bong;Yun, Myung-Hwan;Lim, Ji-Hyoun
    • 대한인간공학회지
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    • 제31권5호
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    • pp.687-694
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    • 2012
  • Objective: This study aims to survey the prevalence of musculoskeletal disorders(MSD) among Korean hospital workers and to analyze the relationship of MSD symptoms and workload perceived by workers. Background: Despite of high exposure to the MSD risk factors and high MSD symptom prevalence among health care workers, there were not enough studies of MSD prevalence among the hospital workers. Method: This study designed a survey based on Nordic questionnaire to obtain MSD symptoms and the degree of four perceived workloads: work repetition, urgency, physical exertion and satisfaction. In this survey, 1,846 workers in a hospital participated. The prevalence of MSD was analyzed for each body part, and MSD cases, which were predetermined in this study, were identified. The relationship between the MSD cases and each perceived workload was analyzed using chi-square test. Results: The pain in the shoulder was the most prevalent among the workers as 52%, and the low back(37%) and leg discomfort(36%) followed. The MSD cases, in which degree of pain was more than severe, were also the most prevalent in the shoulder(13%). Female workers had higher rate of MSD cases than the males. Among the four workload variables, the physical exertion was the statistically related to MSD cases for all the body parts. In addition, the others also had significant relation to MSD cases except one or two body parts. Conclusion: This study found that Korean hospital workers had MSD symptoms mainly in the shoulder, low back and legs in order, and the perceived workload surveyed in this study was highly correlated with MSD symptoms. Application: This study provides another evidence that subjective physical exertion perceived by workers is an important factor to explain MSD cases as same as the objective one.

Halliwick 10 Point Program이 균형능력에 미치는 영향 (The Effect of Halliwick 10 Point Program on the Balance Control)

  • 송명환;손민균;김태열;황태연
    • 대한임상전기생리학회지
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    • 제1권2호
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    • pp.49-60
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    • 2003
  • The purpose of this study was to evaluate the effect of Halliwick 10 point program on the balance control. Fourteen undergraduate students participated in the experiment, and classified 7 experiment and 7 control group, randomly. Halliwick 10 point program was applied in the experiment group for 4 weeks. Balance index was measured using KAT 2000. Balance index were measured before, during(2 weeks), and after(4 weeks) the training for 4 weeks. 2-way repeated measures ANOVA was used to further distinguish between the groups. The following results were obtained; 1. The total balance index scores from a KAT were significantly decreased after 4 weeks compared with before the training passing of time. However there was no significant difference between experiment and control group. 2. The left and anterior shifting balance index scores from a KAT were significantly decreased after 4 weeks compared with before the training passing of time. However there was no significant difference between experiment and control group. These results lead us to the conclusion that the balance ability of women twenties increase as the water is higher than that of the ground applied Halliwick 10 point program of the water specific therapy province. Therefore, A further direction of this study will be to provide more evidence for Halliwick 10 point program in the water specific therapy.

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여성들의 찜질방 이용 현상에 관한 일상 생활 기술적 연구

  • 전정자;유은광
    • 대한간호학회지
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    • 제27권4호
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    • pp.961-974
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    • 1997
  • The ZZimzilbang is a room where many women eagerly go due to the special meaning women give to it related to their health. It is a different type of sauna room which maintains low degree of temperature, consisting of an Ondol room(Korean under-floor heating system, hypocaust) built with mineral stone radiating ultrared rays. Even though many women mention that they utilize it for health, there is no precise evidence of the effects on their health. This ethnographic study sought to define the phenomenon from the perspective of the women who experienced the ZZimzilbang. A convenience sample of 27 women was interviewed during a 15 month period from December 1995 to July 1997 in 12 ZZimzilbangs located in Seoul, Korea. The mean ages of the women 57.3 years ; seventeen women were housekeeper and only eight women had job : twenty women were married and three women among them were widows. The main reasons women patronize the place are : for mitigation and healing of physical signs and symptoms : composure ; safe lodging and boarding : control of outward appearance : control of health ; meeting and fellowship with friends : and custom. The outcomes of the utilization of the place were : mitigation of physical signs and symptoms : psychological tranquility : cosmetic and diet ; good use of spare time : and utilization of services provided there. Most women who visited ZZimzilbang for relief of physical signs and symptoms strongly mentioned a correlation to inadequate Sanhujori, the traditional postpartal and postabortal care for woman. Some of specific kinds of services provided in that place were alternative therapy such as acupuncture, negative cupping, finger-pressure, mugwort steam and various kinds of massage including massage of blood vessels that are influenced by Oriental medicine ; health education of breathing such as abdominal breathing or Danjeon(단전호흡) : and selling of many things including health foods, drugs for osteoporosis, and eutrophics. This study suggests that professional caregivers should further study this phenomenon for the development of adequate care of women with a resulting important in their quality of life.

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