• Title/Summary/Keyword: partial integration

Search Result 124, Processing Time 0.04 seconds

Intrapleural or Intraperitoneal Lobaplatin for Treatment of Patients with Malignant Pleural Effusion or Ascites

  • Huang, Xin-En;Wei, Guo-Li;Huo, Jie-Ge;Wang, Xiao-Ning;Lu, Yan-Yan;Wu, Xue-Yan;Liu, Jin;Xiang, Jin;Feng, Ji-Feng
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.4
    • /
    • pp.2611-2614
    • /
    • 2013
  • Aims: To explore efficacy and side effects of intrapleural or intraperitoneal lobaplatin for treating patients with malignant pleural or peritoneal effusions. Methods: Patients in Jiangsu Cancer Hospital and Research Institute with cytologically confirmed solid tumors complicated with malignant pleural effusion or ascites were enrolled into this study. Lobaplatin (20-30 $mg/m^2$) was intrapleurally or intraperitoneally infused for patients with malignant pleural effusion or ascites. Results: From 2012 to 2013, intrapleural or intraperitonea lobaplatin was administered for patients with colorectal or uterus cancer who were previous treated for malignant pleural effusion or ascites. Partial response was achieved for them. Main side effects were nausea/vomiting, and bone marrow suppression. No treatment related deaths occurred. Conclusion: Intrapleural or intraperitoneal infusion of lobaplatin is a safe treatment for patients with malignant pleural effusion or ascites, and the treatment efficacy is encouraging.

Subparametric Element Based on Partial-linear Layerwise Theory for the Analysis of Orthotropic Laminate Composites (직교이방성 적층구조 해석을 위한 부분-선형 층별이론에 기초한 저매개변수요소)

  • Ahn, Jae-Seok;Woo, Kwang-Sung
    • Journal of the Computational Structural Engineering Institute of Korea
    • /
    • v.22 no.2
    • /
    • pp.189-196
    • /
    • 2009
  • This paper presents the subparametric finite element model formulated by partial-linear layerwise theory for the analysis of laminate composites. The proposed model is based on refined approximations of two dimensional plane for orthotropic thick laminate plate as well as thin case. Three dimensional problem can be reduced to two dimensional case by assuming piecewise linear variation of in-plane displacement and a constant value of out-of-plane displacement across the thickness. The integrals of Legendre polynomials are chosen to define displacement fields and Gauss-Lobatto numerical integration is implemented in order to directly obtain maximum values occurred at the nodal points of each layer without other extrapolation techniques. The validity and characteristics of the proposed model have been tested by using orthotropic multilayered plate problem as compared to the values available in the published references. In this study, the convergence test has been carried out to determine the optimal layer model in terms of central deflection and stresses. Also, the distribution of displacements and stresses across the thickness has been investigated as the number of layer is increased.

Stress Intensity Factor of Single Edge Cracked Plates Considering Materials and Geometry of Patch by p-Convergent Partial Layerwise Model (p-수렴 부분층별모델에 의한 일변균열판의 패치재료 및 기하형상에 따른 응력확대계수)

  • Ahn, Hyeon-Ji;Ahn, Jae-Seok;Woo, Kwang-Sung
    • Journal of the Computational Structural Engineering Institute of Korea
    • /
    • v.23 no.2
    • /
    • pp.191-198
    • /
    • 2010
  • This study investigated that the stress reduction of single edge cracked plates with patch repairs according to different type of patching such as material, size and thickness of patch and adhesive as well as single sided or double sided patches. As a numerical tool, the p-convergent partial layerwise model has been employed. The proposed model is formulated by assuming piecewise linear variation of in-plane displacement and a constant value of out-of-plane displacements across thickness. The integrals of Legendre polynomials are chosen to define displacement fields and Gauss-Lobatto numerical integration is implemented in order to directly obtain maximum values occurred at the nodal points of each layer without other extrapolation techniques. Also, total strain energy release rate method is adopted to obtain stress intensity factors. Numerical examples are presented not only to demonstrate the stress reduction effect in terms of non-dimensional stress intensity factor and deflection with respect to different type of patch repairs, but also the accuracy of proposed model.

Integration of Ba0.5Sr0.5TiO3Epitaxial Thin Films on Si Substrates and their Dielectric Properties (Si기판 위에 Ba0.5Sr0.5TiO3 산화물 에피 박막의 집적화 및 박막의 유전 특성에 관한 연구)

  • Kim, Eun-Mi;Moon, Jong-Ha;Lee, Won-Jae;Kim, Jin-Hyeok
    • Journal of the Korean Ceramic Society
    • /
    • v.43 no.6 s.289
    • /
    • pp.362-368
    • /
    • 2006
  • Epitaxial $Ba_{0.5}Sr_{0.5}TiO_3$ (BSTO) thin films have been grown on TiN buffered Si (001) substrates by Pulsed Laser Deposition (PLD) method and the effects of substrate temperature and oxygen partial pressure during the deposition on their dielectric properties and crystallinity were investigated. The crystal orientation, epitaxy nature, and microstructure of oxide thin films were investigated using X-Ray Diffraction (XRD) and Transmission Electron Microscopy (TEM). Thin films were prepared with laser fluence of $4.2\;J/cm^2\;and\;3\;J/cm^2$, repetition rate of 8 Hz and 10 Hz, substrate temperatures of $700^{\circ}C$ and ranging from $350^{\circ}C\;to\;700^{\circ}C$ for TiN and oxide respectively. BSTO thin-films were grown on TiN-buffered Si substrates at various oxygen partial pressure ranging from $1{\times}10^{-4}$ torr to $1{\times}10^{-5}$ torr. The TiN buffer layer and BSTO thin films were grown with cube-on-cube epitaxial orientation relationship of $[110](001)_{BSTO}{\parallel}[110](001)_{TiN}{\parallel}[110](001)_{Si}$. The crystallinity of BSTO thin films was improved with increasing substrate temperature. C-axis lattice parameters of BSTO thin films, calculated from XRD ${\theta}-2{\theta}$ scans, decreased from 0.408 m to 0.404 nm and the dielectric constants of BSTO epitaxial thin films increased from 440 to 938 with increasing processing oxygen partial pressure.

Pseudo-Integrators in the Evolution of Bores′s Broiler Integration (육계 통합체계(계열화) 전개 과정상의 사이비 계열주체 문제)

  • 김정주;박영인
    • Korean Journal of Poultry Science
    • /
    • v.20 no.2
    • /
    • pp.107-114
    • /
    • 1993
  • The structure change in the broiler industry of Korea has been taking place very rapidly toward the direction of integrated production and marketing system. During the course of the evolution into the integrated structure, however, a number of small business entities, uncountable nationally but a minimum of a dozen, that previously engaged in the supply of production factors or live bird transaction also tended to get involved in the new system as a disguised or pseudo-integrator, having brought a lot of problems not only to the farmers but also to the development of integrated structure. The pseudo-integrator is generally characterized by limited functions in such a way of supplying chicks and feeds to and collecting grown birds from farmers under the contract at a fixed farmer's payment in practically the same pattern as a partial or quasi-integration, which intends to act as if an integrator in a stratagem to simply enjoy a margin simply from selling supplies and buying products for a certain period of time. The grower making a contract with appears to be a farmer who used to be an Independent and speculating but not able to join in the normal system of evolving integration. The problems of a pseudo-integrator center on the financial loss to a contract farmer, because the falsified integrator has to become easily bankrupt and run away when the price of live broiler continually stays below the cost of production, even though he is able to make a tremendous profit otherwise which is the real purpose of the operation for. It is true that the volatile market, fluctuating the price up more than doubled in a month and down to a half in a few weeks, makes the pseudo-integrator find the room for such a fraudulence. In addition, its activity also adversely affect the evolution of the integration due to rather negative image on structure change in general. It is recommended that the farmers need to better understand the real picture of the integrated system so as not to be swindled by a disguised, small scale agribusiness agent. By the same token, it is also equally required to have the whole industry integrated completely as early as possible. The Joint effort to get rid of pseudo-integrators' problems shall be put for the industry development moving toward the integration. No doubt a pseudo-integrator must be a temporary player for chance emerging during the course of structure change into the integrated, though.

  • PDF

Formulation of fully coupled THM behavior in unsaturated soil (불포화지반에 대한 열-수리-역학 거동의 수식화)

  • Shin, Ho-Sung
    • Proceedings of the Korean Geotechical Society Conference
    • /
    • 2010.09a
    • /
    • pp.808-812
    • /
    • 2010
  • A great deal of attention is focused on coupled Thermo-Hydro-Mechanical (THM) behavior of multiphase porous media in diverse geo-mechanical and geo-environmental areas. This paper presents general governing equations for coupled THM processes in unsaturated porous media. Coupled partial differential equations are derived from 3 mass balances equations (solid, water, and air), energy balance equation, and force equilibrium equation. Finite element code is developed from the Galerkin formulation and time integration of these governing equations for 4 main variables (displacement $\underline{u}$, gas pressure $P_g$, liquid pressure $P_l$), and temperature T). The code is validated with theoretical solutions for linear material with simple boundary conditions.

  • PDF

Hydroelastic vibration analysis of wetted thin-walled structures by coupled FE-BE-Procedure

  • Rohr, Udo;Moller, Peter
    • Structural Engineering and Mechanics
    • /
    • v.12 no.1
    • /
    • pp.101-118
    • /
    • 2001
  • The reliable prediction of elastic vibrations of wetted complex structures, as ships, tanks, offshore structures, propulsion components etc. represent a theoretical and numerical demanding task due to fluid-structure interaction. The paper presented is addressed to the vibration analysis by a combined FE-BE-procedure based on the added mass concept utilizing a direct boundary integral formulation of the potential fluid problem in interior and exterior domains. The discretization is realized by boundary element collocation method using conventional as well as infinite boundary element formulation with analytical integration scheme. Particular attention is devoted to modelling of interior problems with both several separate or communicating fluid domains as well as thin-walled structures wetted on both sides. To deal with this specific kind of interaction problems so-called "virtual" boundary elements in areas of cut outs are placed to satisfy the kinematical conditions in partial connected fluid domains existing in realistic tank systems. Numerical results of various theoretical and practical examples demonstrate the performance of the BE-methodology presented.

Generalized Computational Nodes for Pseudospectral Methods

  • Kim, Chang-Joo;Park, Soo Hyung;Jung, Sung-Nam;Sung, Sangkyung
    • International Journal of Aeronautical and Space Sciences
    • /
    • v.15 no.2
    • /
    • pp.183-189
    • /
    • 2014
  • Pseudo-spectral method typically converges at an exponential rate. However, it requires a special set of fixed collocation points (CPs) to get highly accurate formulas for partial integration and differentiation. In this study, computational nodes for defining the discrete variables of states and controls are built independently of the CPs. The state and control variables at each CP, which are required to transcribe an NOCP into the corresponding NLP, are interpolated, using those variables allocated at each node. Additionally, Lagrange interpolation and spline interpolation are investigated, to provide a guideline for selecting a favorable interpolation method. The proposed techniques are applied to the solution of an NOCP using equally spaced nodes, and the computed results are compared to those using the standard PS approach, to validate the usefulness of the proposed methods.

Future trends in multisensor integration and fusion

  • Luo, Ren-C.;Kay, Michael-G.;Lee, W.Gary
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 1992.10b
    • /
    • pp.22-28
    • /
    • 1992
  • The need for intelligent systems that can operate in an unstructured, dynamic environment has created a growing demand for the use of multiple, distributed sensors. While most research in multisensor fusion has revolved around applications in object recognition-including military applications for automatic target recognition-developments in microsensor technology are encouraging more research in affordable, highly-redundant sensor networks. Three trends that are described at length are the increasing use of microsensors, the techniques that are used in the handling of partial or uncertain data, and the application of neural network techniques for sensor fusion.

  • PDF

A Study on the Nonlinear Analysis of Dynamic Response of Shell Structure (Shell 구조물의 비선형 동적응답 해석에 관한 연구)

  • Bae, Dong-Myung;Jin, Jong-Dae
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.28 no.1
    • /
    • pp.79-92
    • /
    • 1992
  • This is analyzed using the finite element method which is appling excellent isoparametric curve element in the aspect of large usages of dynamic responses in which is regarding geometric and material nonlinear of a large scale shell structure of an airplane, a submarine, a ship, and an ocean structure. The solution of dynamic equations is got by direct integration method using time-stepping procedure and regarding Central Difference Method of the both solutions. But because formal matrix factorization is not necessary in each time step and it does not take less time to compute relatively, this method must be regarded very few time steps on the condition. Axisymmatric shell problems are inspected using 8 node Isoparametric element in this paper. Partial axisymmatric spherical shell is used as a model to analyze axisymmatric nonlinear dynamic behavior regarding. Total Lagrangian formulation in geometric nonlinear behavior and elastio-viscoplastic in material nonlinear behavior.

  • PDF