• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2611-2614
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• 2013

Aims: To explore efficacy and side effects of intrapleural or intraperitoneal lobaplatin for treating patients with malignant pleural or peritoneal effusions. Methods: Patients in Jiangsu Cancer Hospital and Research Institute with cytologically confirmed solid tumors complicated with malignant pleural effusion or ascites were enrolled into this study. Lobaplatin (20-30 $mg/m^2$) was intrapleurally or intraperitoneally infused for patients with malignant pleural effusion or ascites. Results: From 2012 to 2013, intrapleural or intraperitonea lobaplatin was administered for patients with colorectal or uterus cancer who were previous treated for malignant pleural effusion or ascites. Partial response was achieved for them. Main side effects were nausea/vomiting, and bone marrow suppression. No treatment related deaths occurred. Conclusion: Intrapleural or intraperitoneal infusion of lobaplatin is a safe treatment for patients with malignant pleural effusion or ascites, and the treatment efficacy is encouraging.

• 한국전산구조공학회논문집
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• 제22권2호
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• pp.189-196
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• 2009

본 논문에서는 적층구조 해석을 위해 부분 선형 층별이론에 의해 정식화된 저매개변수 유한요소 모델을 제안한다. 얇은 직교이방성 문제뿐만 아니라, 두꺼운 식교이방성 적층판 해석을 위해 제안된 모델은 2차원 세분화 기법에 기초를 두고 있다. 즉, 이 모델은 두께방향으로의 면내거동에 대해서는 선형변화로 가정하는 층별분리 이론이 적용되고, 두께방향으로의 면외거동에 대해서는 상수로 가정하는 등가단층이론이 사용된다. 변위장을 정의하기 위해 적분형 르장드르 다항식이 사용된다. 또한 가우스-로바토 적분법을 사용하여, 적층평판의 종래의 가우스적분점이 아닌 절점의 위치에 발생하는 최대응력값을 별도의 외삽법을 사용하지 않고 바로 산출하였다. 제안된 모델의 정당성과 특성은 직교이방성 다층적층판 문제를 사용하여 검증되었으며, 그 결과는 출판된 참고문헌의 값들과 비교되었다. 이 연구에서는 최적의 유한요소 적층모델을 결정하기 위해 응력과 최대처짐을 사용한 수렴성조사가 수행되었다. 또한, 적층 수의 증가에 따른 두께방향으로의 변위와 응력분포의 변화가 조사되었다.

• 한국전산구조공학회논문집
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• 제23권2호
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• pp.191-198
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• 2010

이 연구에서는 접착패치보강의 서로 다른 형태 즉, 패치와 접착제의 재료, 크기, 두께 뿐만 아니라 일면보강 또는 양면보강에 따른 일변균열판의 응력감소에 대한 연구가 수행되었다. 수치해석 도구로는 p-수렴 부분층별 모델이 사용되었다. 이 모델의 면내 변위는 구간별 연속인 선형변화로 가정하였고, 두께방향으로의 면외 변위는 일정한 상수로 가정하여 적용하였다. 변위장의 정의는 적분형 르장드르 다항식을 적용하였고, 수치적분은 별도의 외삽법 없이 각 층별의 절점에서 발생하는 적분값을 바로 얻을 수 있는 가우스-로바토 적분법을 사용 하였다. 또, 에너지 방출률법을 사용하여 응력확대계수를 산출하였다. 수치예제를 통해 제안된 모델의 정확도는 물론이고 접착패치 보강형태에 따라 변화되는 무차원 응력확대계수와 처짐의 항으로 응력감소 효과를 분석하였다.

• 한국세라믹학회지
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• 제43권6호
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• pp.362-368
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• 2006

Epitaxial $Ba_{0.5}Sr_{0.5}TiO_3$ (BSTO) thin films have been grown on TiN buffered Si (001) substrates by Pulsed Laser Deposition (PLD) method and the effects of substrate temperature and oxygen partial pressure during the deposition on their dielectric properties and crystallinity were investigated. The crystal orientation, epitaxy nature, and microstructure of oxide thin films were investigated using X-Ray Diffraction (XRD) and Transmission Electron Microscopy (TEM). Thin films were prepared with laser fluence of $4.2\;J/cm^2\;and\;3\;J/cm^2$, repetition rate of 8 Hz and 10 Hz, substrate temperatures of $700^{\circ}C$ and ranging from $350^{\circ}C\;to\;700^{\circ}C$ for TiN and oxide respectively. BSTO thin-films were grown on TiN-buffered Si substrates at various oxygen partial pressure ranging from $1{\times}10^{-4}$ torr to $1{\times}10^{-5}$ torr. The TiN buffer layer and BSTO thin films were grown with cube-on-cube epitaxial orientation relationship of $[110](001)_{BSTO}{\parallel}[110](001)_{TiN}{\parallel}[110](001)_{Si}$. The crystallinity of BSTO thin films was improved with increasing substrate temperature. C-axis lattice parameters of BSTO thin films, calculated from XRD ${\theta}-2{\theta}$ scans, decreased from 0.408 m to 0.404 nm and the dielectric constants of BSTO epitaxial thin films increased from 440 to 938 with increasing processing oxygen partial pressure.

• 한국가금학회지
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• 제20권2호
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• pp.107-114
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• 1993

The structure change in the broiler industry of Korea has been taking place very rapidly toward the direction of integrated production and marketing system. During the course of the evolution into the integrated structure, however, a number of small business entities, uncountable nationally but a minimum of a dozen, that previously engaged in the supply of production factors or live bird transaction also tended to get involved in the new system as a disguised or pseudo-integrator, having brought a lot of problems not only to the farmers but also to the development of integrated structure. The pseudo-integrator is generally characterized by limited functions in such a way of supplying chicks and feeds to and collecting grown birds from farmers under the contract at a fixed farmer's payment in practically the same pattern as a partial or quasi-integration, which intends to act as if an integrator in a stratagem to simply enjoy a margin simply from selling supplies and buying products for a certain period of time. The grower making a contract with appears to be a farmer who used to be an Independent and speculating but not able to join in the normal system of evolving integration. The problems of a pseudo-integrator center on the financial loss to a contract farmer, because the falsified integrator has to become easily bankrupt and run away when the price of live broiler continually stays below the cost of production, even though he is able to make a tremendous profit otherwise which is the real purpose of the operation for. It is true that the volatile market, fluctuating the price up more than doubled in a month and down to a half in a few weeks, makes the pseudo-integrator find the room for such a fraudulence. In addition, its activity also adversely affect the evolution of the integration due to rather negative image on structure change in general. It is recommended that the farmers need to better understand the real picture of the integrated system so as not to be swindled by a disguised, small scale agribusiness agent. By the same token, it is also equally required to have the whole industry integrated completely as early as possible. The Joint effort to get rid of pseudo-integrators' problems shall be put for the industry development moving toward the integration. No doubt a pseudo-integrator must be a temporary player for chance emerging during the course of structure change into the integrated, though.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 추계 학술발표회
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• pp.808-812
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• 2010

A great deal of attention is focused on coupled Thermo-Hydro-Mechanical (THM) behavior of multiphase porous media in diverse geo-mechanical and geo-environmental areas. This paper presents general governing equations for coupled THM processes in unsaturated porous media. Coupled partial differential equations are derived from 3 mass balances equations (solid, water, and air), energy balance equation, and force equilibrium equation. Finite element code is developed from the Galerkin formulation and time integration of these governing equations for 4 main variables (displacement $\underline{u}$, gas pressure $P_g$, liquid pressure $P_l$), and temperature T). The code is validated with theoretical solutions for linear material with simple boundary conditions.

• Structural Engineering and Mechanics
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• 제12권1호
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• pp.101-118
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• 2001

The reliable prediction of elastic vibrations of wetted complex structures, as ships, tanks, offshore structures, propulsion components etc. represent a theoretical and numerical demanding task due to fluid-structure interaction. The paper presented is addressed to the vibration analysis by a combined FE-BE-procedure based on the added mass concept utilizing a direct boundary integral formulation of the potential fluid problem in interior and exterior domains. The discretization is realized by boundary element collocation method using conventional as well as infinite boundary element formulation with analytical integration scheme. Particular attention is devoted to modelling of interior problems with both several separate or communicating fluid domains as well as thin-walled structures wetted on both sides. To deal with this specific kind of interaction problems so-called "virtual" boundary elements in areas of cut outs are placed to satisfy the kinematical conditions in partial connected fluid domains existing in realistic tank systems. Numerical results of various theoretical and practical examples demonstrate the performance of the BE-methodology presented.

• International Journal of Aeronautical and Space Sciences
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• 제15권2호
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• pp.183-189
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• 2014

Pseudo-spectral method typically converges at an exponential rate. However, it requires a special set of fixed collocation points (CPs) to get highly accurate formulas for partial integration and differentiation. In this study, computational nodes for defining the discrete variables of states and controls are built independently of the CPs. The state and control variables at each CP, which are required to transcribe an NOCP into the corresponding NLP, are interpolated, using those variables allocated at each node. Additionally, Lagrange interpolation and spline interpolation are investigated, to provide a guideline for selecting a favorable interpolation method. The proposed techniques are applied to the solution of an NOCP using equally spaced nodes, and the computed results are compared to those using the standard PS approach, to validate the usefulness of the proposed methods.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 19-21 Oct. 1992
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• pp.22-28
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• 1992

The need for intelligent systems that can operate in an unstructured, dynamic environment has created a growing demand for the use of multiple, distributed sensors. While most research in multisensor fusion has revolved around applications in object recognition-including military applications for automatic target recognition-developments in microsensor technology are encouraging more research in affordable, highly-redundant sensor networks. Three trends that are described at length are the increasing use of microsensors, the techniques that are used in the handling of partial or uncertain data, and the application of neural network techniques for sensor fusion.

• 수산해양기술연구
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• 제28권1호
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• pp.79-92
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• 1992

This is analyzed using the finite element method which is appling excellent isoparametric curve element in the aspect of large usages of dynamic responses in which is regarding geometric and material nonlinear of a large scale shell structure of an airplane, a submarine, a ship, and an ocean structure. The solution of dynamic equations is got by direct integration method using time-stepping procedure and regarding Central Difference Method of the both solutions. But because formal matrix factorization is not necessary in each time step and it does not take less time to compute relatively, this method must be regarded very few time steps on the condition. Axisymmatric shell problems are inspected using 8 node Isoparametric element in this paper. Partial axisymmatric spherical shell is used as a model to analyze axisymmatric nonlinear dynamic behavior regarding. Total Lagrangian formulation in geometric nonlinear behavior and elastio-viscoplastic in material nonlinear behavior.