• Title/Summary/Keyword: optimal pre-treatment

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Evaluation of Particle Removal Rate in Inclined-pipe Settling System for Stormwater Infiltration (강우유출수의 침투시 부하저감을 위한 경사관 침전장치의 효율평가)

  • Kim, Sangrae;Kim, Dongkeun;Mun, Jungsoo;Han, Mooyoung
    • Journal of Korean Society of Water and Wastewater
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    • v.23 no.6
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    • pp.719-726
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    • 2009
  • One of the alternative runoff management measures is on-site runoff mitigation, such as rainwater retention tank and infiltration facilities especially the latter that is possible to manage simultaneously runoff quality and quantity as a perspective of water-cycle. This study was conducted to develop a particle separator, inclined-pipe settling system, that could improve particle removal efficiency of road runoff as a pre-treatment device of stormwater infiltration. Solid particles larger than $100{\mu}m$ are separated by simple sedimentation; however, the significant amount of pollutants with a diameter less than $100{\mu}m$ remain in suspension. Without any treatment in that case of the runoff into infiltrate, groundwater would be deteriorated and also infiltration rate would be decreased by clogging. Therefore, we suggest optimal design parameters (inclined angle, pipe length, and surface loading rate) of inclined-pipe settling system which can be designed to effectively remove particles diameter smaller then $70{\mu}m$. Thus, the results showed TSS removal efficiency more than 80% with a particle diameter between $20{\mu}m$ and $70{\mu}m$, 100% above particle diameter $70{\mu}m$ for the inflow rate $0.018 m^3/m^2{\cdot}hr$ with pipe inclined at angle $15^{\circ}$.

The Inhibition of Epileptogenesis During Status Epilepticus by Ginsenosides of Korean Red Ginseng and Ginseng Cell Culture (Dan25)

  • N.E., Chepurnova;Park, Jin-Kyu;O.M., Redkozubova;A.A., Pravdukhina;K.R., Abbasova;E.V., Buzinova;A.A., Mirina;D.A., Chepurnova;A.A., Dubina;U.A., Pirogov;M., De Curtis;L., Uva;S.A., Chepurnov
    • Journal of Ginseng Research
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    • v.31 no.3
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    • pp.159-174
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    • 2007
  • Pharmacology of Korean Red ginseng gives us unique possibility to develop new class of antiepileptic drugs today and to improve one's biological activity. The chemical structures of ginsenosides (GS) have some principal differences from well-known antiepileptic new generation drugs. The antiepileptic effect of GS was also demonstrated in all models of epilepsy in rats (young and adult), which have studied, in all models of epilepsy including status epilepticus (SE), induced by lithium - pilocarpine. In our experiments in rats new evidences on protective effects were exerted as a result of premedication by GS. Pre-treatment of several GS could induce decrease of the seizures severity and brain structural damage (by MRI), neuronal degeneration in hippocampus. Wave nature of severity of motor seizures during convulsive SE was observed during lithium-pilocarpine model of SE in rats (the first increase of seizures was 30 min after the beginning of SE and the second - 90 min after. The efficacy of treatment on SE by ginsenoside as expected was observed after no less 3 weeks by daily GS i.p. administration. It is blocked SE or significantly decrease the severity of seizures during SE. The implication of presented data is that combination of ginsenosides from Korean Red ginseng and ginseng cell culture Dan25 that could be applied for prevention of epileptical status development. However, a development of optimal ratio of different ginsenosides $(Rb_1$ Rc, Rg, Rf,) should consummate in the new antiepileptic drug development.

Long-Term Management of Seizures after Surgical Treatment of Supratentorial Cavernous Malformations : A Retrospective Single Centre Study

  • Dziedzic, Tomasz A.;Koczyk, Kacper;Nowak, Arkadiusz;Maj, Edyta;Marchel, Andrzej
    • Journal of Korean Neurosurgical Society
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    • v.65 no.3
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    • pp.415-421
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    • 2022
  • Objective : Seizure recurrence after the first-ever seizure in patients with a supratentorial cerebral cavernous malformation (CCM) is almost certain, so the diagnosis and treatment of epilepsy is justified. The optimal method of management of these patients is still a matter of debate. The aim of our study was to identify factors associated with postoperative seizure control and assess the surgical morbidity rate. Methods : We retrospectively analysed 45 consecutive patients with a supratentorial CCM and symptomatic epilepsy in a single centre. Pre- and postoperative epidemiological data, seizure-related patient histories, neuroimaging results, surgery details and outcomes were obtained from hospital medical records. Seizure outcomes were assessed at least 12 months after surgery. Results : Thirty-five patients (77.8%) were seizure free at the long-term follow-up (Engel class I); six (13,3%) had rare, nocturnal seizures (Engel class II); and four (8.9%) showed meaningful improvement (Engel class III). In 15 patients (33%) in the Engel I group; it was possible to discontinue antiepileptic medication. Although there was not statistical significance, our results suggest that patients can benefit from early surgery. No deaths occurred in our study, and mild postoperative neurologic deficits were observed in two patients (4%) at the long-term follow-up. Conclusion : Surgical resection of CCMs should be considered in all patients with a supratentorial malformation and epilepsy due to the favourable surgical results in terms of the epileptic seizure control rate and low postoperative morbidity risk, despite the use of different predictors for the seizure outcome.

Effects of Plant Growth Regulators on In Vitro Germination and Organ Formation of Wild Angelica gigas N. (야생 참당귀(Angelica gigas N.)의 기내발아 및 기관유도에 미치는 PGRs의 영향)

  • Lee, Su-Gwang;Cho, Won-Woo;Lee, Song-Hee;Park, Kwang-Woo;Choi, Kyung;Kang, Ho-Duck
    • Korean Journal of Plant Resources
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    • v.25 no.4
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    • pp.456-464
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    • 2012
  • This study was conducted to establish the in vitro optimal condition for seed germination and organogenesis of wild Angelica gigas. The experiment was evaluated the effects of $GA_3$ for pre-treatment with different periods of time (0h, 24h, 48h, 72h) and followed the treatment of seeds by control, scarification and methanol-heating method. As a result, the highest rates (15%) of seed germination was shown under the treatment without soaking of $GA_3$ and methanol-heating treatment. The seed germination was highly increased 60% under the condition of treatment on ultrasonic waves (frequency 80 KHz) with methanol-heating treatment including 0.1 mg/L $GA_3$. The highest callus induction rate was obtained from in vitro germinated stem, root and hypocotyl on the MS medium with 1.0 mg/L NAA and 0.5 mg/L BA. The highest percentages of shooting (50%) and rooting (85%) induction were observed in hypocotyl and root cultured on PGRs free medium and 0.1 mg/L NAA, respectively. In addition, somatic embryogenesis was observed from stem (1.0 mg/L 2,4-D) and hypocotyl (0.1 mg/L NAA).

Evaluation of Operational Options of Wastewater Treatment Using EQPS Models (EQPS 모델을 이용한 하수처리장 운전 평가)

  • Yoo, Hosik;Ahn, Seyoung
    • Journal of the Korean Society of Urban Environment
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    • v.18 no.4
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    • pp.401-408
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    • 2018
  • EQPS (Effluent Quality Prediction System, Dynamita, France) was applied to analyze the appropriateness of the design of a bioreactor in A sewage treatment plant. A sewage treatment plant was designed by setting the design concentration of the secondary clarifier effluent to total nitrogen and total phosphorus, 10 mg/L and 1.8 mg/L, respectively, in order to comply with the target water quality at the level of the hydrophilic water. The retention time of the 4-stage BNR reactor was 9.6 hours, which was 0.5 for the pre-anoxic tank, 1.0 for the anaerobic tank, 2.9 for the anoxic tank, and 5.2 hours for the aerobic tank. As a result of the modeling of the winter season, the retention time of the anaerobic tank was increased by 0.2 hours in order to satisfy the target water quality of the hydrophilic water level. The default coefficients of the one step nitrification denitrification model proposed by the software manufacturer were used to exclude distortion of the modeling results. Since the process modeling generally presents optimal conditions, the retention time of the 4-stage BNR should be increased to 9.8 hours considering the bioreactor margin. The accurate use of process modeling in the design stage of the sewage treatment plant is a way to ensure the stability of the treatment performance and efficiency after construction of the sewage treatment plant.

A Study on Face Awareness with Free size using Multi-layer Neural Network (다층신경망을 이용한 임의의 크기를 가진 얼굴인식에 관한 연구)

  • Song, Hong-Bok;Seol, Ji-Hwan
    • Journal of the Korean Institute of Intelligent Systems
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    • v.15 no.2
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    • pp.149-162
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    • 2005
  • This paper suggest a way to detect a specific wanted figure in public places such as subway stations and banks by comparing color face images extracted from the real time CCTV with the face images of designated specific figures. Assuming that the characteristic of the surveillance camera allows the face information in screens to change arbitrarily and to contain information on numerous faces, the accurate detection of the face area was focused. To solve this problem, the normalization work using subsampling with $20{\times}20$ pixels on arbitrary face images, which is based on the Perceptron Neural Network model suggested by R. Rosenblatt, created the effect of recogning the whole face. The optimal linear filter and the histogram shaper technique were employed to minimize the outside interference such as lightings and light. The addition operation of the egg-shaped masks was added to the pre-treatment process to minimize unnecessary work. The images finished with the pre-treatment process were divided into three reception fields and the information on the specific location of eyes, nose, and mouths was determined through the neural network. Furthermore, the precision of results was improved by constructing the three single-set network system with different initial values in a row.

Analysis of Varietal Differences in Pre-harvest Sprouting of Rice using RNA-Sequencing (RNA-Sequencing을 이용한 벼 품종간 수발아 차이 분석)

  • Choi, Myoung-Goo;Lee, Hyen-Seok;Hwang, Woon-Ha;Yang, Seo-Yeong;Lee, Yun-Ho;Lee, Chung-gun;Yun, Song Joong;Jeong, Jae-Hyeok
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.65 no.4
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    • pp.274-283
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    • 2020
  • Seed dormancy is an adaptive trait in which seeds do not germinate under unfavorable environmental conditions. Low dormancy seeds are easily germinated under optimal environmental conditions, and these characteristics greatly reduce the yield and quality of crops. In the present study, we compared the pre-harvest sprouting (PHS) rate of two cultivars, Joun and Jopyeong, using the Winkler scale after heading day and temperature of the test. The PHS rate increased as the Winkler scale after heading day increased from 700℃ to 1100℃ and the temperature of the test increased. In all conditions, the PHS rate of Jopyeong was higher than that of Joun. RNA-sequencing was used to analyze the cause of the high PHS rate. We analyzed the biological metabolic processes related to the abscisic acid (ABA) metabolite pathway using the KEGG mapper with selected differentially expressed genes in PHS seeds. We found that the expression of ABA biosynthesis genes (OsNCEDs) was down-regulated and that ABA catabolic genes (OsCYP707As) was up-regulated in PHS seeds. However, the quantitative real-time PCR results showed that Joun had a higher expression of OsNCEDs than that of Jopyeong, but OsCYP707As did not yield a significant result. Joun displayed higher ABA content than that of Jopyeong not only during ripeness time but also during PHS treatment. Taken together, we provided evidence that the ABA content remaining in the seed is important to the PHS rate, which is determined by the expression level of the ABA biosynthesis gene OsNCEDs.

Optimization of Genetic Transformation Conditions for Korean Gerbera Lines (국내 거베라 육종계통 형질전환 기초 조건 확립)

  • Lee, Hye-Young;Lee, Ki-Jung;Jeon, Eun-Hee;Shin, Sang-Hyun;Lee, Jai-Heon;Kim, Doh-Hoon;Chung, Dae-Soo;Chung, Yong-Mo;Cho, Yong-Cho;Kim, Jeong-Kook;Chung, Young-Soo
    • Journal of Plant Biotechnology
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    • v.33 no.1
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    • pp.49-56
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    • 2006
  • Gerber (Gerbera hybrida) is a valuable ornamental species grown as a potted plant and cut flowers. However, genetic variability within the gerbera genus is very limited. So it is absolutely needed to introduce and widen genetic resources into gerbera lines by genetic transformation. For the purpose, 18 Korean gerbera lines were screened to establish Agrobacterium-mediated genetic transformation procedure. In an experiment to select Korean gerbera lines which are amenable to Agrobacterium-inoculation, 12 lines turned out to be positive in Agrobacterium-inoculation. More callus were produced from BA 2ppm, Zeatin 2ppm, IAA 0.2ppm in pre-culture and regeneration medium (2X media) but there was no difference in the frequency of GUS expression rate. In another experiment to find out optimal condition for highly efficient Agrobacterium-inoculation, petiole and leaf explants have been treated with four different pre-culture periods, two different co-culture periods and two different Agrobacterium strains. As a result, high GUS expression has been showed from petiole and leaf explants treated no pre-culture period with LBA4404 Agrobacterium tumerfaciens, 5 day co-culture period and dipping treatment.

Bioethanol Production from Wasted Corn Stalk from Gangwon Province : from Enzymatic Hydrolysis to Fermentation (강원지역 폐옥수수대로부터 바이오에탄올 생산 : 효소 당화부터 발효까지)

  • Choi, Jae Min;Choi, Suk Soon;Yeom, Sung Ho
    • Applied Chemistry for Engineering
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    • v.23 no.3
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    • pp.326-332
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    • 2012
  • Among the samples prepared by various pre-treatment methods, the one pretreated by dilute sulfuric acid showed the highest glucose yield in the enzymatic hydrolysis. Statistical analysis of enzymatic hydrolysis revealed that the glucose yield was in proportion to the enzyme dosage, the ratio of the pre-treated sample to the buffer solution, and the reaction time and that the effect of enzyme dosage was predominant in the experiment range. In addition, the glucose yield was estimated to be 76.1% at an optimal enzymatic hydrolysis condition. In a separate hydrolysis and fermentation (SHF), Saccharomyces cerevisiae converted over 80% of glucose from the enzymatic hydrolysis of pre-treated wasted corn stalk by dilute sulfuric acid to bioethanol with 37% of ethanol yield and 0.42 $g/L{\cdot}hr$ of productivity. In the simultaneous saccharification and fermentation (SSF), 59.5% of conversion from glucan to ethanol and 0.20 $g/L{\cdot}hr$ of productivity were achieved. In both SHF and SSF, approximately 88 g of bioethanol could be obtained from 1 kg of wasted corn stalk. The possible amount of bioethanol in Gangwon province were estimated to be 1.9 kiloton with the assumption of the 50% of collection ratio.

Evaluation of stress-induced analgesia in acupuncture analgesic effect - An Approach on diameters of acupuncture needles and acupuncture point needlings - (침진통 효과에서 스트레스에 의한 진통 효과 개입 여부 평가 - 침굵기, 침자극 부위를 중심으로 -)

  • Jeong, Byeong-Ju;Choe, Il-Hwan;Shin, Hee-Sup;Lim, Sabina
    • Korean Journal of Acupuncture
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    • v.25 no.3
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    • pp.65-80
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    • 2008
  • Objective : In recent years, many investigators have questioned whether the analgesic effect of acupuncture is simply related to the stress-induced analgesia (SIA). However, there has been lack of studies on this issue. In this study, the stress levels induced by manual acupunctures are compared with the stress in animal experiment models. The experiments have been carried out with Sprague Dawley (SD) rats. Method : For stress level evaluation, Hot plate test has been used. Maximum Possible Effect (MPE) has been measured by checking the pre-test time and post-test time. Cortisol and corticosterone concentrations in serum were measured by enzyme-linked immunosorbent assay (ELISA). Results : In the hot plate test, MPE values of post-test time were significantly decreased after 10 minutes than after 5 minutes. Therefore, optimal time interval was chosen as 10 minutes. There was significant difference of MPE values between Suspension group and all other treatment groups. However, there were no significant differences of MPE values between Sham group and all other treatment groups. However, MPE values showed tendency to decrease when acupuncture needle diameter increased. MPE values of ST040, ST040(lido), NAP040(lido) groups were markedly decreased than that of Suspension group, while that of NAP040 group was substantially increased than that of Sham group increased in acupoint and nonacupoint models. Serum cortisol concentrations of treatment groups were not significantly different from that of Suspension and Sham groups. Serum corticosterone concentration of 0.25 mm group was substantially increased than that of compared with Sham group. Serum cortisol and corticosterone concentrations of treatment groups were not significantly different from those of Suspension and Sham groups in acupoint and nonacupoint models. Conclusion : From hot plate test and serum stress hormones concentrations, it is found that manual acupuncture treatment induces negligible stress or SIA on ST36. And the stress induced by manual acupuncture is more closely related to acupuncture point needlings than diameters of acupuncture needles.

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