• Parasites, Hosts and Diseases
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• 제53권1호
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• pp.43-49
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• 2015

The aim of the study was to explore the possible molecular markers of chloroquine resistance in Plasmodium vivax isolates in Thailand. A total of 30 P. vivax isolates were collected from a malaria endemic area along the Thai-Myanmar border in Mae Sot district of Thailand. Dried blood spot samples were collected for analysis of Pvmdr1 and Pvcrt-o polymorphisms. Blood samples ($100{\mu}l$) were collected by finger-prick for in vitro chloroquine susceptibility testing by schizont maturation inhibition assay. Based on the cut-off $IC_{50}$ of 100 nM, 19 (63.3%) isolates were classified as chloroquine resistant P. vivax isolates. Seven non-synonymous mutations and 2 synonymous were identified in Pvmdr1 gene. Y976F and F1076L mutations were detected in 7 (23.3%) and 16 isolates (53.3%), respectively. Analysis of Pvcrt-o gene revealed that all isolates were wild-type. Our results suggest that chloroquine resistance gene is now spreading in this area. Monitoring of chloroquine resistant molecular markers provide a useful tool for future control of P. vivax malaria.

• Journal of the Korean Wood Science and Technology
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• 제43권6호
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• pp.818-825
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• 2015

전통 목조건축물의 보존을 위해 국내 전역에 서식하는 일본흰개미 아종(Reticulitermes speratus kyushuensis)의 방제에 적합한 흰개미 예찰제어기 제형을 개발하고 실내 실험 및 현장적용성 평가를 수행하였다. 실내 실험 결과를 통해 적합한 제형을 구성하였으며, 보다 빠른 군체제거가 가능한 독먹이로써 피프로닐 0.001% (w/w)이 선정되었다. 흰개미 예찰제어기는 기존 군체제거제와 다르게 지면에 설치된 상태 그대로 흰개미 가해 여부를 육안으로 관찰할 수 있어 효율적인 모니터링이 가능하였다. 2013년 3월부터 10월까지 전남 순천 송광사 권역에서 수행된 현장적용성 평가 결과 총 367개 중 약 9.8%에 해당하는 36개에서 흰개미가 탐지되었으며, 군체제거약제 교체 후 36개 모두에서 흰개미 군체가 제거되거나 활성이 감소됨을 확인할 수 있었다.

• Nutrition Research and Practice
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• 제10권3호
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• pp.342-351
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• 2016

BACKGROUND/OBJECTIVES: This study aims to develop a mobile nutritional management program for integration into the already developed web-based program, Diabetes Mellitus Dietary Management Guide (DMDMG) for diabetic patients. Further, we aim to evaluate the amended DMDMG program. SUBJECTS/METHODS: The mobile application based on an Android operating system includes three parts: 1) record of diet intake, which allows users to take pictures of the meal and save to later add diet records into DMDMG; 2) an alarm system that rings at each meal time, which reminds users to input the data; 3) displays the diet record and the results of nutrient intake, which can be also viewed through the web program. All three parts are linked to the web-based program. A survey was conducted to evaluate the program in terms of nutrition knowledge, dietary attitude, eating behavior and diet intake by non-equivalent control group design among diabetic patients with 14 DMDMG users and 12 non-user controls after a one-month trial of DMDMG. RESULTS: Non-users did not use the program, but participated in the weekly off-line nutrition classes for one month. The program users showed increased healthful dietary behavior (P < 0.01) and dietary attitude scores (P < 0.05). More DMDMG users had higher nutrition knowledge scores after one-month trial than non-users. However, dietary intake significantly increased in non-user group for calcium and sodium (P < 0.05) while the user group did not show significant changes. CONCLUSIONS: The program has created positive changes in patients' dietary life. All the users were satisfied with the program, although some expressed minor difficulties with an unfamiliar mobile app.

• 한국정보통신학회논문지
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• 제8권1호
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• pp.18-27
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• 2004

본 논문에서는 다 채널 무선전송시스템에서 RF증폭기(SSPA)의 비 선형과 백-오프동작에 따른 기저대역 디지털변조신호의 왜곡을 분석하였다. OFDM 다 채널 무선전송시스템에서 적용되는 SiGe HBT의 바이어스 전류를 가변 시켜 설계한 SSPA의 비 선형 전력전달함수를 구하고 이 전달함수에 수학적으로 비 선형 모델링 함수와 비교 분석함으로서 최적 바이어스조건을 구하였다. RF 증폭기에 입력전력을 가변 시켰을 때 SSPA의 대역-내에서의 출력전력과 대역-외에서의 출력전력을 구했으며, 입력전력에 따른 디지털 변조신호의 성상도 왜곡을 분석하였다. 본 연구의 결과는 선형동작을 위한 RF증폭기의 적응바이어스 설계와 선형화를 위한 SSPA의 백-오프 동작 최적 바이어스를 결정하는데 매우 유용하게 응용될 수 있다.

• 방송공학회논문지
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• 제15권5호
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• pp.617-630
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• 2010

고해상도 비디오에 대한 압축 성능 향상을 위해 ITU-T VCEG에서는 H.264/AVC 표준을 근간으로 다양한 압축 성능 개선 기법들을 추가해 왔는데, 그중 ALF 기법은 양자화에 의해 발생한 오류를 제거할 수 있는 필터링 방법을 제공함으로써, 고해상도 영상에서 평균 9%의 매우 높은 성능 개선 능력을 보이는 핵심 기술이다. 하지만 기존의 ALF는 한 프레임 내에서 하나의 Wiener 필터만을 사용하므로, 다수의 서로 다른 통계적 특성을 가진 영역이 존재하는 경우에는 능률적인 오류 복원 성능을 제공하기 어려운 한계를 가지고 있다. 따라서 본 논문에서는 한 복호 프레임에 존재하는 다양한 영역 별 통계적 특성을 반영하여 보다 유연한 율-왜곡 관점에서의 ALF 선택이 가능할 수 있도록, 적응적 율-왜곡 최적 다중 루프 필터 기법을 제안한다. 제안 알고리즘을 통해 다양한 영상에 대하여 기존 알고리즘의 성능을 안정적으로 개선할 수 있었으며, 영상에 뚜렷한 특성 차이를 지닌 복수의 오브젝트가 존재할 경우에는 더욱 높은 비트율 감소 이득을 얻을 수 있었다.

• 융합신호처리학회논문지
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• 제19권3호
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• pp.97-103
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• 2018

본 논문에서는 비정상적인 과도상태에서의 개선된 해상 전투체계 UPS(Uninterruptable Power Supply) 시스템을 다룬다. 기존에는 일시적인 과전압 및 과전류에 대응하기 위하여 서미스터와 바리스터 소자를 사용하고 있지만 시스템 운용 중에 발생하는 비정상 과도전압에는 취약하므로 UPS가 비가용 상태로 되는 경우가 빈번히 발생하였다. 이를 극복하고 UPS 시스템을 보호하기 위하여 본 논문에서는 초기 입력전원 및 운용 중에 발생되는 비정상 과도전압을 감지한 입력 전원 차단회로, 전원제어 시퀀스 개선, 그리고 인버터 및 CPU 오동작 방지 방법 등을 제안한다. 제안된 방법으로 UPS 구현된 시스템은 Programmable AC/DC 발생기를 이용하여 입력전원 가변 시험을 통하여 시뮬레이션을 수행하였으며, 최종적으로 해상 전투체계의 다기능콘솔에 장착하여 현장시험을 통하여 신뢰성과 안정성을 검증하였다.

• Journal of Microbiology and Biotechnology
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• 제19권1호
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• pp.83-92
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• 2009

Individual immunochromatographic assays (ICG) for ochratoxin A (OTA) and zearalenone (ZEA) were optimized and used in the development of a one-step simultaneous immunochromatographic assay (OS-ICG) for the rapid multianalysis of two mycotoxins in corn samples. The nitrocellulose membrane of the OS-ICG was treated with OTA-bovine serum albumin (BSA), ZEA-ovalbumin (OVA), and anti-mouse IgG in the OTA test, ZEA test, and control zones, respectively. Monoclonal antibody-gold conjugates (OTA3 MAb-gold and ZEA2C5 MAb-gold) were sprayed onto the conjugate pad. The visual detection limits were 2.5 and 5 ng/ml for OTA and ZEA, respectively, and the results were obtained within 15 min after starting the analysis. An efficient, simple, and rapid extraction method using 30% MeOH/PBS was established and validated by analyzing the corn samples spiked with OTA/ZEA mixtures (0/0, 5/10, 10/20, and $20/30\;{\mu}g/kg$). The cut-off values of the OS-ICG for the spiked corn were 5 and $10\;{\mu}g/kg$ for OTA and ZEA, respectively. Natural corn samples were analyzed by OS-ICG, direct competitive enzyme-linked immunosorbent assay (DC-ELISA), and HPLC. Results of the OS-ICG were in good agreement with those obtained by DC-ELISA and HPLC. The developed OS-ICG offers a rapid, easy-to-use, and portable analytical system and can be used as a convenient qualitative tool for the on-site simultaneous determination of OTA and ZEA in cereals, food, and agricultural products in one analytical cycle.

• Journal of Astronomy and Space Sciences
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• 제19권3호
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• pp.215-224
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• 2002

This paper describes EGSE design for the small satellite such like KOMPSAT-2 satellite. Recent design trend of small satellite and EGSE is to take short development time and less cost. For this purpose, the design for KOMPSAT-2 satellite and EGSE are not much modified from KOMPSAT-1 heritage. It means that it is able to be accommodated the verified hardware and software modules used in KOMPSAT-1 satellite program if possible. The objective of EGSE is to provide hardware and software for efficient electrical testing of integrated KOMPSAT-2 satellite in three general categories. (1) Simulators for ground testing (e.g. solar-simulation power, earth scenes, horizons and sun sensor). (2) Ground station type satellite data acquisition and processing test sets. (3) Overall control of satellite using hardline datum. In KOMPSAT (KOrea Multi-Purpose SATellite) program, KOMPSAT-2 EGSE was developed to support satellite integration and test activities. The KOMPSAT-2 EGSE was designed in parallel with satellite design. Consequently, the KOMPSAT-2 EGSE was based on the KOMPSAT-1 heritage since the spacecraft design followed the heritage. The KOMPSAT-2 baseline was elaborated by taking advantage of experience from KOMPSAT-1 program. The EGSE of KOMPSAT-2 design concept is generic modular design with preference in part selection with commercial off-the-shelf which were proven from KOMPSAT-1 programs, flexible/user friendly operational environment (graphical interface preferred), minimized new design and self test capability.

• The Journal of Korean Physical Therapy
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• 제22권1호
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• pp.67-73
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• 2010

Purpose: We tested whether repetitive transcranial magnetic stimulation (rTMS) improved recovery following spinal cord injury (SCI) in rats with transplantation of adipose tissue-derived stromal cells (ATSCs). Methods: Twenty Sprague-Dawley rats (200-250 g, female) were used. Moderate spinal cord injury was induced at the T9 level by a New York University (NYU) impactor. The rat ATSCs (approximately $5{\times}10^5$ cells) were injected into the perilesional area at 9 days after SCI. Starting four days after transplantation, rTMS (25 Hz, 0.1 Tesla, pulse width=$370{\mu}s$, on/off time=3 sec/3 sec) was applied daily for 7 weeks. Functional recovery was assessed using the Basso, Beattie, and Bresnahan (BBB) locomotor rating scale as well as pain responses for thermal and cold stimuli. Results: Both groups showed similar, gradual improvement of locomotor function. rTMS stimulation decreased thermal and cold hyperalgesia after 7 weeks, but sham stimulation did not. Conclusion: rTMS after transplantation of ATSCs in an SCI model may reduce thermal hyperalgesia and cold allodynia, and may be an adjuvant therapeutic tool for pain control after stem cell therapy in SCI.

• 상하수도학회지
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• 제29권2호
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• pp.183-192
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• 2015

Response surface methodology (RSM) based on a Box-Behnken Design (BBD) was applied to optimize the thermal-alkaline pre-treatment operating conditions for anaerobic digestion of flotation scum in food waste leachate. Three independent variables such as thermal temperature, NaOH concentration and reaction time were evaluated. The maximum methane production of 369.2 mL $CH_4/g$ VS was estimated under the optimum conditions at $62.0^{\circ}C$, 10.1% NaOH and 35.4 min reaction time. A confirmation test of the predicted optimum conditions verified the validity of the BBD with RSM. The analysis of variance indicated that methane production was more sensitive to both NaOH concentration and thermal temperature than reaction time. Thermal-alkaline pretreatment enhanced the improvement of 40% in methane production compared to the control experiment due to the effective hydrolysis and/or solubilization of organic matters. The fractions with molecular weight cut-off of scum in food waste leachate were conducted before and after pre-treatment to estimate the behaviors of organic matters. The experiment results found that thermal-alkaline pre-treatment could reduce the organic matters more than 10kD with increase the organic matters less than 1kD.