• Tuberculosis and Respiratory Diseases
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• v.41 no.5
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• pp.484-488
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• 1994

Background : The antigen-specific receptor on the surface of most peripheral T lymphocytes is a disulfide-linked heterodimer composed of $\alpha$ and $\gamma$ subunits, noncovalently associated with CD3 polypeptides. Recently, a novel type of CD3-associated heterodimer was described on a T cell subset that does not express CD4 or CD8 molecules. This second type of TCR dimer is composed of chains encoded for by the $\gamma$- and $\delta$-TCR genes. These cells may exert both cytotoxic and lymphokine producing functions. Although it was reported that some ${\gamma}{\delta}$-TCR might recognize an MHC-linked determinant, the funεtion or physiologic ligand for this new receptor is not yet clear. It was found that ${\gamma}{\delta}$-TCR can react with 65 kD heat shock protein of M. tuberculosis, which suggests the possible protective role of ${\gamma}{\delta}$ T lymphocytes against tuberculosis. In our previous study, there was neither the increase in number nor the functional activation of ${\gamma}{\delta}$ T cells in the peripheral blood from patients with pulmonary tuberculosis. Now we report the distribution of ${\gamma}{\delta}$ T cells in the regional sites of M. tuberculosis infection, especial1y tuberculous lymphadenitis. Methods : Lymph nodes from patients with pathologically-proven tuberculous lymphadenopathy (n=5) and reactive hyperplasia (n=3) were used. Tissues were frozen in liquid nitrogen immediately after removal and stored below $-70^{\circ}C$. The cryostat sections of these frozen specimens were stained with anti-Leu-4 Ab, Identi-T TCR ${\delta}1$, and Identi-T ${\beta}F1$. The number of positively stained cells were counted at high power field. Results : The infiltration of ${\gamma}{\delta}$ T cells was significantly higher in the lymph nodes from patients with tuberculous lymphadenopathy than that with reactive hyperplasia ($16.3{\pm}10.3%$ vs. $1.7{\pm}1.5%$). Conclusion : These results suggest that ${\gamma}{\delta}$) T cells may play a role in the defense against M. tuberculosis infection, especially in the regional sites of infection.

• The KIPS Transactions:PartC
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• v.17C no.3
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• pp.281-290
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• 2010

In geographic forwarding algorithms, traditional route maintenance requires mobile nodes periodically exchange beacon messages with their neighbors. In beacon message based forwarding scheme, a longer interval reduces the number of beacons needed, but may result in significant location errors. Conversely, a shorter interval guarantees more accurate location information, but induces control overheads.Therefore, the fixed or dynamic interval scheme based forwarding schemes cannot adapt well to different mobility environments. Also, existing schemes result in the uncertainty of neighbor node's position in the forwarding table of mobile node. Therefore, this paper presents a self-adaptive location checking mechanism based proactive geo-routing algorithm for beacon-based geographic routing. Simulation results show that the proposed routing algorithm not only significantly increases the relay transmission rate but also guarantees the high end-to-end packet delivery in low and high mobility environments.

• The KIPS Transactions:PartA
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• v.16A no.4
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• pp.299-306
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• 2009

Hierarchical Folded HyperStar Network has lower network cost than HCN(n,n) and HFN(n,n) which are hierarchical networks with the same number of nodes. In this paper, we analyze embedding between Hierarchical Folded HyperStar HFH($C_n,C_n$) and Hypercube, HCN(n,n), HFN(n,n). The results of embedding are that HCN(n,n), HFN(n,n) and Hypercube $Q_{2n}$ can be embedded into HFH($C_n,C_n$) with expansion $\frac{C^n}{2^{2n}}$ and dilation 2, 3, and 4, respectively. Also, HFH($C_n,C_n$) can be embedded into HFN(2n,2n) with dilation 1. These results mean so many developed algorithms in Hypercube, HCN(n,n), HFN(n,n) can be used efficiently in HFH($C_n,C_n$).

• The KIPS Transactions:PartC
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• v.15C no.4
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• pp.289-296
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• 2008

In wireless mesh network, studies on routing protocols have been actively carried out recently, and hop count is used as a major routing metric in destination-sequenced distance-vector (DSDV) routing protocol, which is a representative proactive routing protocol. Although hop-by-hop multi-path (HMP) DSDV and enhanced HMP (EHMP) DSDV routing protocols perform routing by considering both hop count and residual bandwidth within one hop distance nodes, it has a shortcoming that routing is carried out via non-optimal path from the aspect of end-to-end routing. In order to overcome the shortcoming, a cost-aware multi-path (CAMP) DSDV routing protocol is proposed in this paper, which considers hop count and end-to-end minimum residual bandwidth. Simulation results based on NS-2 show that the proposed routing protocol performs better than DSDV, HMP DSDV, and EHMP DSDV protocols from the aspect of throughput and packet delivery ratio, by appropriately using hop count and end-to-end minimum residual bandwidth information and has the same number of management messages with HMP DSDV and EHMP DSDV protocols.

• Journal of Bio-Environment Control
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• v.27 no.1
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• pp.54-63
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• 2018

Red and blue lights are effective wavelengths for photosynthesis in plants. In this study, we determined the effects of various combined ratios of red to blue LEDs on the quality of cherry tomato seedlings prior to transplantation, and their subsequent effects on the yield and quality of tomato fruits after transplanting. Two-week-old cherry tomato seedlings (Solanum lycopersicum cv. 'Cuty') were cultivated under various combined ratios of red (R; peak wavelength 655 nm) to blue (B; 456 nm) LEDs [red:blue = 41:59 (59B), 53:47 (47B), 65:35 (35B), 74:26 (26B), 87:13 (13B), or 100:0 (0B)] and fluorescent lamps and raised for 27 days. The cherry tomato seedlings were subsequently transplanted into a venlo-type greenhouse and cultivated for 75 days. At the seedling stage, the shoot fresh weight of seedlings in all RB combined treatments, except 0B and 59B, was higher than that of the control after 27 days of LED treatment. Shoot dry weight and leaf area also showed trends similar to that of shoot fresh weight. The stem length was significantly higher in 13B, 26B, and 35B treatments compared with the control and other treatments. In particular, the stem length of 26B plants was approximately 3.2 times longer than that of 59B plants. At 37 days after transplanting, the number of nodes was significantly higher in 26B and 47B plants, and the plant height of 26B plants was significantly higher than that of control and 59B plants. Total fruit yield in 26B plants, which was the highest, was approximately 1.6 and 1.8 times higher than that in control and 59B plants, respectively. Thus, the results of this study indicate that various combined ratios of red to blue LEDs directly affected to the growth of cherry tomato seedlings and may also affect parameters of reproductive growth such as fruit yield after transplantation.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.68 no.4
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• pp.304-312
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• 2023

Plant breeding is a time-consuming process, mainly due to the limited annual generational advancement. A speed breeding system, using LED light sources, has been applied to accelerate generational progression in various crops. However, detailed protocols applicable to soybeans are still insufficient. In this study, we report the optimized protocols for a speed breeding system comprising 12 soybean varieties with various maturity ecotypes. We investigated the effects of two light qualities (RGB ratio), three levels of light intensity (PPFD), and two soil conditions on the flowering time and development of soybeans. Our results showed that an increase in the red wavelength of the light spectrum led to a delay in flowering time. Furthermore, as light intensity increased, flowering time, average internode length, and plant height decreased, while the number of nodes, branches, and pods increased. When compared to agronomic soil, horticultural soil resulted in an increase of more than 50% in the number of nodes, branches, and pods. Consequently, the optimal conditions were determined as follows: a 10-hour short-day photoperiod, an equal RGB ratio (1:1:1), light intensity exceeding 1,300 PPFD, and the use of horticultural soil. Under these conditions, the average flowering time was found to be 27.3±2.48 days, with an average seed yield of 7.9±2.67. Thus, the speed breeding systems reduced the flowering time by more than 40 days, compared to the average flowering time of Korean soybean resources (approximately 70 days). By using a controlled growth chamber that is unaffected by external environmental conditions, up to 6 generations can be achieved per year. The use of LED illumination and streamlined facilities further contributes to cost savings. This study highlights the substantial potential of integrating modern crop breeding techniques, such as digital breeding and genetic editing, with generational shortening systems to accelerate crop improvement.

• Korean Journal of Veterinary Research
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• v.38 no.4
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• pp.793-802
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• 1998

Salmonellosis caused by a number of serotypes of Salmonella is an infectious, acute or chronic, zoonotic disease and characterized by enteritis and diarrhea, septicemia in animal. In these studies we investigated the prevalent serotypes of Salmonella causing animal salmonellosis in Korea and the 71 strains of Salmonella spp. were isolated from materials such as mesenteric lymph nodes, fecal samples from slaughtered animal. With the identification test results, the most prevalent serotypes were, in order, S stanley 31 strains (43.7%), S typhimurium 19 strains (26.8%) and S montevideo 11 strains (15.5%), respectively. And we could establish the method for detection of antibodies to broad variety of Salmonella serotypes. Lipopolysaccharide(LPS) antigen extracted from Salmonella was more sensitive and specific than outer membrane protein antigen from that for detection of Salmonella antibody by using an indirect ELISA. The optimal concentration of antigen was 100ng/ml of LPS, the dilutions of conjugate and serum were 1 : 1,000~2,000 and 1 : 200~400, respectively. The mix LPS-ELISA which was used by mixing LPS from S typhimurium (group B), S choleraesuis (group C) and S enteritidis (group D) were more rapid and effective than that used LPS from individual strain for detection of Salmonella serogroup O4, O7 and O9 antibody at the same time. We could obtain the high values of optical density ($0.73{\pm}0.32$) by mix LPS-ELISA on the farm which had occurred salmonellosis, but very low values of $0.17{\pm}0.06$ on the negative farm of salmonellosis. So, the mix LPS-ELISA may be used to monitor the serological surveillance for the presence of infection with a number of serotypes of Salmonella and would be useful for prevention and control of salmonellosis in animal.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.39 no.3
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• pp.18-31
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• 2002

In this study, we introduce a concept of advanced neurofuzzy polynomial networks(ANFPN), a hybrid modeling architecture combining neurofuzzy networks(NFN) and polynomial neural networks(PNN). These networks are highly nonlinear rule-based models. The development of the ANFPN dwells on the technologies of Computational Intelligence(Cl), namely fuzzy sets, neural networks and genetic algorithms. NFN contributes to the formation of the premise part of the rule-based structure of the ANFPN. The consequence part of the ANFPN is designed using PNN. At the premise part of the ANFPN, NFN uses both the simplified fuzzy inference and error back-propagation learning rule. The parameters of the membership functions, learning rates and momentum coefficients are adjusted with the use of genetic optimization. As the consequence structure of ANFPN, PNN is a flexible network architecture whose structure(topology) is developed through learning. In particular, the number of layers and nodes of the PNN are not fixed in advance but is generated in a dynamic way. In this study, we introduce two kinds of ANFPN architectures, namely the basic and the modified one. Here the basic and the modified architecture depend on the number of input variables and the order of polynomial in each layer of PNN structure. Owing to the specific features of two combined architectures, it is possible to consider the nonlinear characteristics of process system and to obtain the better output performance with superb predictive ability. The availability and feasibility of the ANFPN are discussed and illustrated with the aid of two representative numerical examples. The results show that the proposed ANFPN can produce the model with higher accuracy and predictive ability than any other method presented previously.

• Journal of Korean Society of Transportation
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• v.21 no.1
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• pp.53-63
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• 2003

The Origin-Destination(OD) matrix is very important in describing transport movements in a region. The OD matrix can be estimated using traffic counts on links in the transport network and other available information. This information on the travel is often contained in a target OD matrix and traffic counts in links. To estimate an OD matrix from traffic counts, they are the major input data which obviously affects the accuracy of the OD matrix estimated, Generally, the quality of an estimated OD matrix depends much on the reliability of the input data, and the number and locations of traffic counting points in the network. Any Process regarding the traffic counts such as the amount and their location has to be carefully studied. The objective of this study is to select of the optimal location of traffic counting points for the OD matrix estimation. The model was tested in nationwide network. The network consists of 224 zones, 3,125 nodes and 6,725 links except to inner city road links. The OD matrix applied for selection of traffic counting points was estimated to 3-constrained entropy maximizing model. The results of this study follow that : the selected alternative to the best optimal counting points of six alternatives is the alternative using common links of OD matrix and vehicle-km and traffic density(13.0% of 6,725 links), however the worst alternative is alternative of all available traffic counting points(44.9% of 6,725 links) in the network. Finally, it should be concluded that the accuracy of reproduced OD matrix using traffic counts related much to the number of traffic counting points and locations.

• Journal of Gastric Cancer
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• v.10 no.1
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• pp.26-33
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• 2010

Purpose: We wanted to evaluate the technical feasibility and safety of totally laparoscopic total gastrectomy (TLTG) for treating early gastric cancer. Materials and Methods: The medical records of 11 consecutive patients who underwent TLTG after being diagnosed with early gastric cancer at Incheon St. Mary's Hospital, The Catholic University of Korea from February 2005 to September 2009 were retrospectively reviewed and their clinicopathologic characteristics and the surgical results wereinvestigated. Results: The mean operation time was $385.6{\pm}94.1$ minutes, the mean time for creating an intracorporeal anastomosis was $97.5{\pm}60.0$ minutes and the mean number of the harvested lymph nodes was $46.6{\pm}15.4$ The mean number of days after operation until starting a liquid diet was the $6.1{\pm}7.6^{th}$ postoperative day and the mean hospital stay after surgery was $14.2{\pm}11.9$ days. There was no case of open conversion, but there were 2 cases of intraoperative complication and 3 cases of postoperative complication. There was one case of postoperative mortality. The patient suffered from thrombocytopenia of an unknown cause, which was refractory to platelet transfusion, on $4^{th}$ postoperative day and the patient died of intraabdominal bleeding on the $6^{th}$ postoperative day. Conclusion: TLTG was a technically feasible and relatively safe procedure. However, a long time for creating the intracoproeal anastomosis and a long operation time are still problems to be solved.