• Clinical and Experimental Pediatrics
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• v.58 no.8
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• pp.275-282
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• 2015

While the incidence of nephrotic syndrome (NS) is decreasing in Korea, the morbidity of difficult-to-treat NS is significant. Efforts to minimize treatment toxicity showed that prolonged treatment after an initial treatment for 2-3 months with glucocorticosteroids was not effective in reducing frequent relapses. For steroid-dependent NS, rituximab, a monoclonal antibody against the CD20 antigen on B cells, was proven to be as effective, and short-term daily low-dose steroids during upper respiratory infections reduced relapses. Steroid resistance or congenital NS are indications for genetic study and renal biopsy, since the list of genes involved in NS is lengthening.

• Composites Research
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• v.25 no.5
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• pp.141-146
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• 2012

The strength design for the lightweight bicycle wheel made of the Carbon/Epoxy composite laminates has been discussed in this paper. For bicycle wheel design, lightness of the wheel is important. Also, it has to satisfy the required strength under specific loading cases. Two testing methods for the bicycle wheel, i.e. vertical and complex loadings, are adopted in this study. Because the strengths of composite wheel is different in relation to the stacking sequence and the number of plies, it is important to decide an appropriate stacking sequence and number of layers for the composite wheel. From the finite element analysis results, the most stable sequence orientation and number of layers are determined. The stacking sequence $[0]_{8n}$, $[90]_{8n}$, $[0/90]_{2ns}$, $[{\pm}45]_{2ns}$, $[0/{\pm}45/90]_{ns}$ (n=1,2,3,4)are performed for finite element analysis. From results, $[0/{\pm}45/90]_{3s}$ lay-up is a good selection for the composite bicycle wheel. Also, the weakest point and layer are found in this study.

• Korean Journal of Optics and Photonics
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• v.14 no.5
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• pp.515-520
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• 2003

Characteristics of an amplifier with repetition rate of a few KHz is investigated. The continuous flash lamp pumped Nd:YAG laser head is used as an amplifier. The thermally induced birefringence of the laser medium is compensated and the depolarization is reduced to 5% in a double-pass amplifier. The amplification factor of a four pass amplifier reaches to about 3.2 at the repetition rate 5-10 KHz and the pulse width is lengthened from 40 ns to 48 ns.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.1
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• pp.56.2-56.2
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• 2013

Compact binaries are important sources of gravitational waves. They are also prime targets for long baseline laser interferometers. In this talk, we present latest progresses made in the Galactic merger rate calculations for compact binaries in the Galactic disk, with an emphasis on NS-NS binaries. For the first time, the non-recycled pulsar found in the Double Pulsar system (PSR J0737-3039B) is included in the rate calculation. We then discuss the prospects of detecting gravitational waves for Earth-based detectors such as advanced LIGO (Laser Interferometer Gravitational-wave Observatory) in US and advanced Virgo in Europe, extrapolating the Galactic rate estimates up to the detection volume of the advanced LIGO-Virgo network, Our results support the expectation that gravitational waves emitted from compact binary mergers will be detected within a decade. However, the detection rate of gravitational waves associated with NS-NS mergers is most likely to be several per year that is much smaller than what has been previously known.

• Proceedings of the Korean Information Science Society Conference
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• 2001.04a
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• pp.331-333
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• 2001

현재 사용되고 있는 라우팅 프로토콜들은 정적인 인자를 사용하여 최단 거리 경로를 설정하기 때문에 혼잡(Congestion)이 자주 발생 할 뿐 아니라 최단 거리 경로를 설정하는 이들 라우팅 프로토콜로는 혼잡상황을 해결하기 어렵다. 이를 해결하기 위해서 트래픽 엔지니어링 기법이 등장하게 되었다. 트랙픽 엔지니어링을 위해서는 네트워크의 동적인 상태를 반영하는 정보를 저장하는 트래픽 엔지니어링 데이터베이스가 필요하다. 현대 NS-2에는 프래픽 엔지니어링에 필요한 정보를 제공하고, 네트워크의 상태에 따라 동적으로 경로를 설정하는 라우팅 프로토콜이 구현되어 있지 않다. 본 논문에서는 NS-2에 구현되어 있는 rtProtoLS라는 Link-State Protocol을 수정하여 플러딩(Flooding) 하는 정보에 동적인 인자의 하나인 가용 대역폭을 정보를 실어서 트래픽 엔지니어링 데이터베이스에 제공 할 수 있도록 하고, 가용 대역폭 정보를 기반으로 하여 동적으로 새로운 경로를 계산 할 수 있는 기능을 추가한 QoS를 고려한 Link-State Protocol(QLS)을 구현하였다. 그리고 본 논문에서는 기존의 라우팅 기법 중 거리 백터 프로토콜(Distance Vector Protocol) 라우팅과 QLS 라우팅의 성능을 Throughput 측면에서 비교, 분석했다.

• Journal of the Korean Society of Food Culture
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• v.19 no.5
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• pp.506-515
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• 2004

This study was carried on the quality characteristics of cake prepared with Co(com oil) containing MCT(medium chain triglycerides), which is used as a fat substitute. In tile cake prepared with MCT-CO containing $10{\sim}30%$ MCT, the appearance and the degree of gelatinization were similar to those of cake prepared with NS-CO(non-substituted corn ell) Cake batter prepared with MCT-CO showed higher specific gravity and consistency than those of cake prepared with NS-CO and increased by increasing MCT contents. The baking loss of cake prepared with MCT-CO was more than that of cake prepared with NS-CO and increased by increasing MCT contents as well. The rheological properties of cake represented significant different by MCT substitution ratio(p<0.05). Gumminess, hardness and chewiness of cake prepared with MCT-CO containing $20{\sim}30%$ MCT were about 2 times higher than those of cake prepared with NS-CO, while springiness and cohesiveness showed similar pattern between the cake prepared with MCT-CO or NS-CO. In sensory evaluation, appearance. color and flavor of cake prepared with CO substituted by MCT up to 100% were better assessed and the taste was better in range of 30% MCT-CO but the texture was less accepted than that of cake prepared with NS-CO.

• Journal of Korean Academy of Nursing
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• v.54 no.3
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• pp.340-357
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• 2024

Purpose: This study aimed to develop a Hybrid Clinical Practicum Environment Scale for Nursing Students (HCPES-NS) and verify its validity and reliability. Methods: The HCPES-NS was constructed following the DeVellis guidelines. The initial items were written based on a literature review and individual in-depth interviews. Content validity was verified through an expert panel review. To confirm the validity and reliability of the scale, a survey was conducted with 449 nursing students enrolled in 12 nursing colleges. Data were analyzed using item analysis, exploratory factor analysis, confirmatory factor analysis, concurrent validity, and reliability tests. Results: Factor analysis showed that the HCPES-NS consists of 15 items on five subdomains: clinical site atmosphere, interpersonal relationship, alternative online practicum contents, provision of learning information, and clinical performance facilitation. A higher score indicated a more positive perception of the clinical practicum environment. The concurrent validity of the HCPES-NS was confirmed by its positive correlation with the Clinical Learning Environment Scale (r = .77). The Cronbach's α reliability of the HCPES-NS was .84. Conclusion: The HCPES-NS is both valid and reliable. This scale reflects the clinical practicum environment and includes an online practicum factor. It may be used effectively by faculty members and educators to evaluate nursing students' perceptions of clinical practicum environments.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.351-358
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• 2016

An Electrical Point Machine (NS:New-type Switch), which is equipped and operated at railways in Korea, has been used since the 1960s after being imported from Japan. On the other hand, although the mechanical configuration has improved the position motor control circuit, the electrical connection has not been improved, so NS may have a problem, such as the interlocking system of automatic train operation. In addition, NS is the most vulnerable part in the railway system and a huge train accident may occur due to minor defects. The existing NS wiring set of the circuit controller should be checked only if fixed. Therefore, an excessive inspection time only by a Railroad Signal expert is required. In this paper, the improvement of electrical connection in a NS wiring set, such as the position motor control circuit, was developed and the prototype was installed at Seoul Metro in the distance to go section. The results can be used to help make appropriate adjustments. The improvement of the NS wiring set enhance the maintenance efficiency, passenger service and the stability of the signal system as well as reducing the maintenance cost.

• Korean Journal of Plant Resources
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• v.32 no.2
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• pp.109-115
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• 2019

In this study, we evaluated the anti-cancer activity and potential molecular mechanism of 70% ethanol extracts of branches from Taxillus yadoriki parasitic to Neolitsea sericea (TN-NS-B) against human lung cancer cells, A549. TY-NS-B dose-dependently suppressed the growth of A549 cells. TY-NS-B decreased ${\beta}$-catenin protein level, but not mRNA level in A549 cells. The downregulation of ${\beta}$-catenin protein level by TY-NS-B was attenuated in the presence of MG132. Although TY-NS-B phosphorylated ${\beta}$-catenin protein, the inhibition of $GSK3{\beta}$ by LiCl did not blocked the reduction of ${\beta}$-catenin by TY-NS-B. In addition, TY-NS-B decreased ${\beta}$-catenin protein in A549 cells transfected with Flag-tagged wild type ${\beta}$-catenin or Flag-tagged S33/S37/T41 mutant ${\beta}$-catenin construct. Our results suggested that TN-NS-B may downregulate ${\beta}$-catenin protein level independent on $GSK3{\beta}$-induced ${\beta}$-catenin phosphorylation. Based on these findings, TY-NS-B may be a potential candidate for the development of chemopreventive or therapeutic agents for human lung cancer.

• Journal of Photoscience
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• v.11 no.32
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• pp.71-74
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• 2004

The macrocycle L exhibited a switch on-off behavior through the fluorescent responses by aromatic imine molecule 1 (X=H) / trifluoroacetic acid (TFA). In the 'switch on' state, it was supposed that the aromatic imine molecule 1 is in the cavity of macrocycle L and a photoinduced electron transfer (PET) from the nitrogen of azacrown part to the anthryl group is inhibited by the interaction between the aromatic imine molecule 1 and the azacrown part of macrocycle L. In the 'switch off' state, it was supposed that the protonated imine molecule 1 is induced by the continuous addition of TFA and a repulsion between the protonated azacrown part and the protonated imine molecule 1 is occurred. It was considered that this process induces the intermolecular PET from the protonated imine molecule 1 to the anthryl group of macrocycle L because of a proximity effect between the anthryl group and the protonated imine molecule 1. From the investigation of the transient emission decay curve, the macrocycle L showed three components (3.45 ns (79.72%), 0.61 ns (14.53%), and 0.10 ns (5.75%). When the imine molecule 1 was added in the macrocycle L as molar ratio=1:1, the first main component showed a little longer lifetime as 3.68 ns (82.75%) although the other two components were similar as 0.64 ns (14.28%) and 0.08 ns (2.96%). On the contrary, when the imine molecule 3 (X=C1) was added in the macrocycle L as molar ratio=l:1, all the three components were decreased such as 3.27 ns (69.83%), 0.44 ns (13.24%), and 0.06 ns (16.93%). The fluorescent pH titration of macrocycle L was carried out from pH=3 to pH=9. The macrocycle L and C $U^{2+}$- macrocycle L complex were intersected at about pH=5, while the E $u^{3+}$ -macrocycle L complex was intersected at about pH=5.5. In addtion, we investigated the fluorescence change of macrocycle L as a function of the substituent constant ($\sigma$$_{p}$$^{o}$) showing in the para-substituent with electron withdrawing groups (X=F, Cl) and electron donating groups (X=C $H_3$, OC $H_3$, N(C $H_3$)$_2$), respectively, as well as non-substituent (X=H).).ctively, as well as non-substituent (X=H).