• Proceedings of the IEEK Conference
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• 2000.06e
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• pp.117-120
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• 2000

Pulse oximetry is a well established non-invasive optical technique for monitoring the SpO$_2$ during anaesthesia, recovery and intensive care. Pulse oximeters determine the oxygen saturation level of blood by measuring the light absorption of arterial blood. The sensors consists of red and infrared light sources and photodetectors. In the measurement of the hemoglobin oxygen saturation, conventional method has required the technique of filtering of remove the noise, and of complex signal processing algorithm. So much time have required to signal processing. In this research, we separate AC signal and DC signal in the stage of signal detection. We filter the noise from each signal and convert A/D. We obtain the SpO$_2$ using the DSP algorithm.

• Proceedings of the KIEE Conference
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• 2007.04a
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• pp.43-45
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• 2007

We developed a portable urodynamics monitoring system using personal digital assistance (PDA) and proposed a new method for measuring the abdominal pressure in non invasive mode using surface EMG signals. This system is consisted of a signal conditioning and control module and could measure the vesical, abdominal and detrusor pressure. The result showed a high correlation coefficient between the practical abdominal pressure, using a conventional rectal catheter and the estimated values, by our proposed algorithm (r=0.81). This system should prove a useful tool in the future evaluations of ambulatory urodynamics monitoring study.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.8
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• pp.1251-1255
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• 2015

The purpose of this study is to measurement the cardiac output using hand to hand impedance method to provide convenience to user when measuring SV(stroke volume) with the use of ICG(Impedance Cardiography). We suggest the optimized modified formula, which can be applied when using impedance with the use of hand to hand Impedance. To verify this formula, a SV from transthoracic approach and hand to hand approach are compared for the 36 subjects, respectively. The acquired data was analyzed by using LabVIEW 8.6, analysis was implemented by SPSS 12.0. Fine difference was shown by individual. We showed that as a result of analyzing the ICG measurement value on thoracic and hand to hand, the correlation with SV was r=0.716, thereby having indicated the results of regression model in relatively high correlation.

• Physical Therapy Korea
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• v.22 no.3
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• pp.98-105
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• 2015

Muscular dystrophy is a hereditary musculoskeletal disorder caused by a mutation in the dystrophin gene. Duchenne muscular dystrophy (DMD) is one of the most common, and progresses relatively faster than other muscular dystrophies. It is characterized by progressive myofiber degeneration, muscle weakness and ultimately ambulatory loss. Since it is an X-linked recessive inheritance, DMD is mostly expressed in males and rarely expressed or less severe in females. The most effective measurement tool for DMD is magnetic resonance imaging (MRI), which allows non-invasive examination of longitudinal measurement. It can detect progressive decline of skeletal muscle size by measuring a maximal cross-sectional area of skeletal muscle. Additionally, other techniques in MRI, like $T_2$-weighted imaging, assess muscle damage, including inflammation, by detecting changes in $T_2$ relaxation time. Current MRI techniques even allow quantification of metabolic differences between affected and non-affected muscles in DMD. There is no current cure, but physical therapist can improve their quality of life by maintaining muscle strength and function, especially if treatment (and other forms of medical intervention) begins in the early stages of the disease.

• Journal of the Optical Society of Korea
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• v.13 no.1
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• pp.166-170
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• 2009

NIRS (Near-infrared spectroscopy) is a relatively, new, non-invasive, and non-ionizing method of measuring hemodynamic responses in thick biological tissues such as the cerebral cortex. In this study, we measured the hemodynamic responses of the rat barrel cortex to whisker stimulation by using a frequency-domain NIRS system. We designed multiple optical probes comprising multi-mode optical fibers and manipulating arms, both of which can be easily applied to small animals. Various electrical stimulations were applied to rat whiskers at different voltage levels and stimulation frequencies. Our results show that the hemodynamic responses are highly dependent on the stimulation voltage level, and not so much on stimulation frequency. This paper suggests that NIRS technology is highly suitable for the study of small animal brains.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.1
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• pp.220-226
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• 2011

Device of the ECG and pulse signal was made to measure PTT signal using non-invasive method and possible to wearable. PTT alterations were observed according to position change using implemented system.It was needed to ECG and pulse to detect the PTT, used the photoplethymorgraphy appeared to change the blood volume. And also wireless sensor node which was able to Zigbee compatibility was used to transfer the detected ECG and pulse signal to PC. Noise was removed from transit data and algorithm was applied to calculate the PTT. After the evaluation of both the conventional measuring systems and the proposed photoplethymography measuring system, a highly effective and efficient formation and distribution sequences were found within the proposed photoplethymography measuring system.

• Journal of Biomedical Engineering Research
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• v.29 no.3
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• pp.198-204
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• 2008

Uroflowmetry is a non-invasive clinical test useful for screening benign prostatic hyperplasia(BPH) common in the aged men. The current standard way to obtain the urinary flow rate is to continuously acquire the urine weight signal proportional to volume over time. The present study proposed an alternative technique measuring pressure to overcome noise problems present in the standard weight measuring technique. Experiments were performed to simultaneously acquire both weight and pressure changes during urination of 9 normal men. Noise components were separated from volume signals converted from both weight and pressure signals based on the polynomial signal model. Signal-to-noise ratio was defined as the ratio of the energies between signal and noise components of the measured volume changes, which was 8.5 times larger in the pressure measuring technique, implying that cleaner signal could be obtained, more immune to noisy environments. When four important diagnostic parameters were estimated, excellent correlation coefficients higher than 0.99 were resulted with mean relative errors less than 5%. Therefore, the present pressure measurement seemed valid as an alternative technique for uroflowmetry.

• Journal of Periodontal and Implant Science
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• v.32 no.2
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• pp.291-302
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• 2002

In most of the previous studies, invasive and discrete techniques have been used to monitor the healing process of the gingival graft. However, Laser Doppler Flowmetry(LDF, floLAB(R), Moor Instruments Ltd., England) is a non-invasive technique for measurement of blood flow in the tissue and also allows continuous monitoring. Thus, we tested the usefulness of LDF in monitoring the healing process of free gingival graft at gingival recession. Eleven gingival graft site of 7 patients, including 5 males and 2 females, aged between 21 and 41 years (mean age 28.5) were monitored for the blood flow. The blood flow in gingival graft at coronal site, central site, apical site, mesial site and distal site was measured using LDF. Blood flow was measured at 1- week, 2- week, 3- week and 4- week after gingival graft surgery from 10 a.m. to 2 p.m. Time-course of the healing process was evaluated by statistical analysis using repeated ANOVA and Duncan test. The results were as follows : (1) Blood flow stayed increased for 2 weeks, and then, it was a tendency to decrease. (2) The blood flow at distal site had always higher than mesial site during the measuring periods. (3) The blood flow was high orderly after 1 week ; most coronal site, most apical site, central site. But that was high orderly after 2 week, 3 week, 4 week ; most coronal site, central site, most apical site. In conclusion, LDF was a useful and clinically adaptable method to monitor wound healing process. Our study suggested that it was important to protect surgical site to promote initial wound healing.

• Journal of Biomedical Engineering Research
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• v.23 no.5
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• pp.397-403
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• 2002

Urine glucose monitoring system is a self-monitoring system that display the glucose level by non-invasive measurement method. In this paper, We developed a noninvasive urine glucose monitoring system that improved defects of urine glucose measurement with a colorimeter method and invasive blood glucose measurement method. This system consist of bio-chemical sensor for urine glucose measurements, signal detecting part, digital and signal analysis part, display part and power supplying part. The developed bio-chemical sensor for the measurement of urine glucose has good reproducibility, convenience of handing and can be mass-produced with cheap price. To evaluate the performance of the developed system, We performed the evaluation of confidence about the detection of glucose level by a comparison between a standard instrument in measuring glucose level and the developed system using standard glucose solutions mixed with urine. Standard error was 2.85282 from the evaluation of confidence based on regression analysis. Also, In analysis of S.D(standard deviation) and C.V(coefficient of validation) that are important parameters to evaluate system using bio-chemical sensor, S.D was 10% which falls under clinically valid value, 15%, and C.V was under 5%. Consequently from the above results, compared to blood glucose measurement, the system performance is satisfactory.

• The Journal of Korean Academy of Prosthodontics
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• v.41 no.2
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• pp.182-206
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• 2003

Statement of problem : Successful osseointegration of endosseous threaded implants is dependent on many factors. These may include the surface characteristics and gross geometry of implants, the quality and quantity of bone where implants are placed, and the magnitude and direction of stress in functional occlusion. Therefore clinical quantitative measurement of primary stability at placement and functional state of implant may play a role in prediction of possible clinical symptoms and the renovation of implant geometry, types and surface characteristic according to each patients conditions. Ultimately, it may increase success rate of implants. Purpose : Many available non-invasive techniques used for the clinical measurement of implant stability and osseointegration include percussion, radiography, the $Periotest^{(R)}$, Dental Fine $Tester^{(R)}$ and so on. There is, however, relatively little research undertaken to standardize quantitative measurement of stability of implant and osseointegration due to the various clinical applications performed by each individual operator. Therefore, in order to develop non-invasive experimental method to measure stability of implant quantitatively, the resonance frequency analyzer to measure the natural frequency of specific substance was developed in the procedure of this study. Material & method : To test the stability of the resonance frequency analyzer developed in this study, following methods and materials were used : 1) In-vitro study: the implant was placed in both epoxy resin of which physical properties are similar to the bone stiffness of human and fresh cow rib bone specimen. Then the resonance frequency values of them were measured and analyzed. In an attempt to test the reliability of the data gathered with the resonance frequency analyzer, comparative analysis with the data from the Periotest was conducted. 2) In-vivo study: the implants were inserted into the tibiae of 10 New Zealand rabbits and the resonance frequency value of them with connected abutments at healing time are measured immediately after insertion and gauged every 4 weeks for 16 weeks. Results : Results from these studies were such as follows : The same length implants placed in Hot Melt showed the repetitive resonance frequency values. As the length of abutment increased, the resonance frequency value changed significantly (p<0.01). As the thickness of transducer increased in order of 0.5, 1.0 and 2.0 mm, the resonance frequency value significantly increased (p<0.05). The implants placed in PL-2 and epoxy resin with different exposure degree resulted in the increase of resonance frequency value as the exposure degree of implants and the length of abutment decreased. In comparative experiment based on physical properties, as the thickness of transducer increased, the resonance frequency value increased significantly(p<0.01). As the stiffness of substances where implants were placed increased, and the effective length of implants decreased, the resonance frequencies value increased significantly (p<0.05). In the experiment with cow rib bone specimen, the increase of the length of abutment resulted in significant difference between the results from resonance frequency analyzer and the $Periotest^{(R)}$. There was no difference with significant meaning in the comparison based on the direction of measurement between the resonance frequency value and the $Periotest^{(R)}$ value (p<0.05). In-vivo experiment resulted in repetitive patternes of resonance frequency. As the time elapsed, the resonance frequency value increased significantly with the exception of 4th and 8th week (p<0.05). Conclusion : The development of resonance frequency analyzer is an attempt to standardize the quantitative measurement of stability of implant and osseointegration and compensate for the reliability of data from other non-invasive measuring devices It is considered that further research is needed to improve the efficiency of clinical application of resonance frequency analyzer. In addition, further investigation is warranted on the standardized quantitative analysis of the stability of implant.