• 제목/요약/키워드: needs-driven

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Diversification and domain evolution of molluskan metallothioneins: a mini review

  • Nam, Yoon Kwon;Kim, Eun Jeong
    • Fisheries and Aquatic Sciences
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    • 제20권6호
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    • pp.8.1-8.18
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    • 2017
  • Background: Metallothionein (MT) is a multifunctional protein playing important roles in homeostatic regulation and detoxification of metals. Mollusk species have been considered as useful sentinel platforms for MT-based biomarker approaches, and they have been reported to display an extraordinary structural diversity of MT proteins. However, potential diversity of molluskan MTs has not been fully explored and recent updates have suggested the need of revision of evolutionary hypothesis for molluskan MTs. Results: Based on bioinformatic analysis and phylogenetic evidences, novel divergence mechanisms and paths were hypothesized in both gastropod and bivalve MT groups. Our analyses are suggestive of the taxon- or lineage-specific domain multiplication/duplication from the ancestral or prototypic MT. Diversification and selection of molluskan MTs might be driven by the needs for acquiring metal selectiveness, specialized novel function, and improved capacity of metal detoxification under environmentally stressed conditions. Conclusion: The structural diversity and variations of molluskan MTs are significantly larger than previously understood. Undoubtedly, molluskan MTs have undergone dynamic divergent processes in their evolutionary histories, giving rise to the great diversity of domain structures in extant MT isoforms. Novel evolutionary paths for molluskan MTs newly proposed in this review could shed additional light onto the revision of the hypothesis for evolutionary differentiation of MTs in the molluskan lineage.

토양측정망과 특정토양오염관리대상시설 부지 등에서 토양오염조사의 효율성 제고를 위한 환경정책의 고찰

  • 박용하;박상열;양재의
    • 한국지하수토양환경학회:학술대회논문집
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    • 한국지하수토양환경학회 2006년도 총회 및 춘계학술발표회
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    • pp.11-15
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    • 2006
  • Attempts were made to increase an efficiency of soil contamination investigation systems (SCISs) including Soil Network and Special Soil Contamination Management Facility Sites in Korea. In order to increase low efficiencies resulting from inappropriate SCISs, possible policy suggestions are driven based on the results from problem findings of Korean policy and comparisons of policies on industrialized countries including United States, United Kingdom, Germany, the Netherlands and Japan. First, functions of Soil Environment Conservation Act (SECA) on liability should be updated and reinforced to initiate a soil contamination investigation process for stakeholders including an owner(s) or a responsible party(ies) of the potentially soil contamination sites positively. Second, appropriate SCISs should be emerged for implementing the Soil Network and Special Soil Contamination Management Facility Sites properly. Stakeholders for the potentially contaminated sites should easily access and raise the soil contamination issues, and soil contamination investigation implemented by liable and profit environment (consulting) companies should be encouraged. Third, the soil contamination reporting system of SECA needs to change legally responsible. Further more, public announcement system showing soil quality of a site which exceeds a certain scale would be considerable. Fourth, liable environment (consulting) companies should legally execute Soil Environment Assessment of SECA.

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후두적출자의 음성재활 - 기관식도천자법 이외의 방법 - (Voice Rehabilitation Other than Tracheo - Esophageal Shunt Method -)

  • 김영호
    • 대한후두음성언어의학회지
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    • 제19권1호
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    • pp.28-30
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    • 2008
  • The problem of voice restoration after total laryngectomy has existed ever since Billroth's first total laryngectomy in 1873. Since then, all the efforts to restore the voice was tried to divert the tracheal air to the pharynx to produce voice, which became the tracheo-esophageal shunt voice currently used. With the intact pharyngoesophagus, however, there are two basic options for speech rehabilitation : the artificial larynx and esophageal voice. The artificial larynx is an electrically driven buzzer or a sound transducer and its most common type is placed against a supple point on patient's neck and introduces a mechanical sound into the tissues and air spaces of the neck. This sound, emanating form the mouth, is articulated by the intact structures of the remaining vocal tract as understandable speech. Esophageal voice is a commonly recommended method for alaryngeal speech rehabilitation, which can be successfully done by regurgitating the air stored in the esophagus. Successful esophageal voice is preferable to the artificial larynx but, most patients usually adapt only one of those methods according to their needs and feasibility to learn.

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마이크로캡슐에 의한 폴리에스테르 직물의 천연염색에 관한 연구(II) - 황금을 중심으로 - (Natural Dyeing of Polyester Fabric with Microcapsules(II) - Scutellaria baicalensis -)

  • 민경혜
    • 한국의류산업학회지
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    • 제10권6호
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    • pp.1045-1050
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    • 2008
  • Developing of high technology, productivity of the fiber product has being rapidly increased and also various kinds of advanced treatment process lead consumer's needs to more high functional, clean and healthy goods. Moreover, increasing in the concern of eco-friendly material and processing, it has been getting popular that the dyeing method like as using natural dyes is more eco-friendly and natural-friendly treatment process. The method, used in this study, adhesion by binding with micro-capsulized natural material to fabric has low change in quality by external influence and high ability in spray effect by broken capsule which comes to pressure and friction when it dressed. Also it has wide application from natural fiber to synthetic fiber. The purpose of this study is development of multi-functional synthetic material with micro-capsulized Scutellaria baicalensis on PET. Moreover, it was driven by comparison of colormetric properties and fastness between regular dip-dyeing method and binding with micro-capsulized material method. Dye ability was arranged mostly low exhaustion but the PET treated by micro-capsule was more or less better than the dip-dyeing PET. Through the SEM(Scanning Electron Microscope) of PET treated by micro-capsule, it has good residence of capsules even after 5 or 10 times washing. Wash and light fastness was arranged some different grade by each condition but mostly high achievement and the micro-capsulized PET was more improved than regular dip-dyed PET.

Auto Regulated Data Provisioning Scheme with Adaptive Buffer Resilience Control on Federated Clouds

  • Kim, Byungsang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제10권11호
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    • pp.5271-5289
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    • 2016
  • On large-scale data analysis platforms deployed on cloud infrastructures over the Internet, the instability of the data transfer time and the dynamics of the processing rate require a more sophisticated data distribution scheme which maximizes parallel efficiency by achieving the balanced load among participated computing elements and by eliminating the idle time of each computing element. In particular, under the constraints that have the real-time and limited data buffer (in-memory storage) are given, it needs more controllable mechanism to prevent both the overflow and the underflow of the finite buffer. In this paper, we propose an auto regulated data provisioning model based on receiver-driven data pull model. On this model, we provide a synchronized data replenishment mechanism that implicitly avoids the data buffer overflow as well as explicitly regulates the data buffer underflow by adequately adjusting the buffer resilience. To estimate the optimal size of buffer resilience, we exploits an adaptive buffer resilience control scheme that minimizes both data buffer space and idle time of the processing elements based on directly measured sample path analysis. The simulation results show that the proposed scheme provides allowable approximation compared to the numerical results. Also, it is suitably efficient to apply for such a dynamic environment that cannot postulate the stochastic characteristic for the data transfer time, the data processing rate, or even an environment where the fluctuation of the both is presented.

현재 기후 모의실험에서 나타나는 지중해의 기후에 대한 전 지구, 원격, 지역 영향들 (Global, Remote, and Local Effects on the Mediterranean Climate in Present-Day Simulations)

  • 김고운;서경환
    • 대기
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    • 제30권3호
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    • pp.311-318
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    • 2020
  • Impacts on the atmospheric circulation and ocean system over the Mediterranean during boreal summer are investigated using Coupled Model Intercomparison Project Phase 5 (CMIP5) historical simulations (from 1911 to 2005). As the climate warms, global and remote effects lead to a strengthening in descending motion, an increase in sea surface temperature (SST) and surface dryness, but a decrease in marine primary production over the Western Mediterranean. The global effect is estimated from interannual variability over the global mean SST and the remote effect is driven by diabatic forcing generated from the South and East Asian summer monsoons. On the other hand, a local contribution leads to the strengthened descending motion and increased surface dryness over the Eastern Mediterranean, whereas the marine primary production over this region tends to increase due to possibly the urban wastewater and sewage. Our result suggests that particular attention needs to be paid to conserve the marine ecosystem over the Mediterranean.

개념 설계 평가를 위한 제품 품질지수 (Product Quality Index for Concept Design Evaluation)

  • 정진하;박영원
    • 한국생산제조학회지
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    • 제19권4호
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    • pp.521-528
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    • 2010
  • A product system will be improved continually until requirements are satisfied. It is true that considering alternative designs to improve product system is hard work; it is also true that selecting an adequate design idea that represents the needs of stakeholders concerned and meets effectiveness factors properly is not an easy work, either. In the process of driv-ing an idea and designing, which is called Design Phase, there are lots of existing tools for testing the driven idea in DFSS. But, those kinds of tools do not offer the function that helps to select the technically better design idea among alternative design ideas that have the same evaluation level. Moreover it is inappropriate to select adequate alternative design ideas by just verifying only the evaluation table in pugh matrix, since satisfied deviation val-ues are low when there is a too competitive mass product system in a market. Also, for the IT product with short life cycle, faster and more effective testing tool is needed. Therefore, the 'roduct quality index' is suggested in order to select an appropriate candidate design concept for system development that meets requirements by using 'deality concept' pro-vided by TRIZ. According to the result of this research, it is possible to select technically better idea fast and effectively; it is confirmed by applying the approach to the case of LCD BLU (Back Light Unit).

기술발전에 따른 생존모형 선정 (Selection of Survival Models for Technological Development)

  • 오현승;김종수;이한교;임동순;조진형
    • 산업경영시스템학회지
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    • 제32권4호
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    • pp.184-191
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    • 2009
  • In a technological driven environment, a depreciation estimate which is based on traditional life analysis results in a decelerated rate of capital recovery. This time pattern of technological growths models needs to be incorporated into life analysis framework especially in those industries experiencing fast technological changes. The approximation technique for calculating the variance can be applied to the six growth models that were selected by the degree of skewness and the transformation of the functions. For the Pearl growth model, the Gompertz growth model, and the Weibull growth model, the errors have zero mean and a constant variance over time. However, transformed models like the linearized Fisher-Pry model, the linearized Gompertz growth model, and the linearized Weibull growth model have increasing variance from zero to that point at which inflection occurs. It can be recommended that if the variance of error over time is increasing, then a transformation of observed data is appropriate.

차세대 전동차용 직접 구동용 매입형 영구자석 동기전동기의 특성 고찰 (Investigation on Direct Driven IPMSM for Next Generation Locomotive)

  • 김민석;박지성;김대광;김정철;정상용
    • 한국철도학회논문집
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    • 제11권4호
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    • pp.398-403
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    • 2008
  • 전동차용 견인전동기 시스템은 저항 및 쵸퍼 제어에 의한 직류 전동기 방식에서 인버터 제어에 의한 유도전동기 방식으로 발전하였다. 오늘날 유도전동기 기술은 어느 정도 성숙기에 접어들었지만 최근에는 소음제거, 효율 극대화 및 유지보수 비용 절감 등의 이점이 있는 감속기를 제거한 직접 구동용 영구자석 전동기가 새로이 각광받고 있다. 특히 기계적으로 견고한 매입형 영구자석 동기전동기는 출력/토크 밀도가 높고 약계자 제어성이 우수하며 고효율 운전이 가능하다. 본 논문은 자기적 포화특성이 심한 영구자석 전동기를 대상으로 고급화된 비선형 수치해석 기법을 적용하여 설계된 전동기의 특성해석을 나타낸다.

BLDC 서보 모터 펌프를 이용하는 직동력(PBW) 구동시스템의 DSP 제어기 및 구동기 설계 (Design of a DSP Controller and Driver for the Power-by-wire(PBW) Driving System Using BLDC Servo Motor Pump)

  • 주재훈;심동석;최중경
    • 한국정보통신학회논문지
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    • 제15권5호
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    • pp.1207-1212
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    • 2011
  • 본 논문은 BLDC 서보모터 펌프를 사용하는 PBW(power-by-wire) 시스템을 위한 DSP(Digital Signal Processor) 제어기에 대한 연구를 제시한다. PBW 유압 엑츄에이터는 BLDC 서보모터에 의해 구동되는 유압펌프와 유압 실린더 그리고 제어기로 구현된다. 이 PBW 시스템은 유압 실린더의 선형 추진 동작을 위해 서보 모터의 속도 제어를 필요로 한다. 본 논문에서는 벡터 제어 방법과 MIN-MAX PWM 기술을 활용하는 서보 제어기를 구현한다. 제어기로서, PWM 파형발생기, A/D변환기, SPI(직병렬인터페이스) 포트 그리고 많은 입/출력 포트 등을 가지고 있는 이유로 TMS320F2812 DSP가 채택되었다.