• Title/Summary/Keyword: mrp

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KAI1/CD82 and MRP1/CD9 Serve as Markers of Infiltration, Metastasis, and Prognosis in Laryngeal Squamous Cell Carcinomas

  • Zhang, Bing-Hui;Liu, Wei;Li, Liang;Lu, Jian-Guang;Sun, Ya-Nan;Jin, De-Jun;Xu, Xiu-Yu
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3521-3526
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    • 2013
  • Objective: The current study explored the expression of KAI1/CD82 and MRP1/CD9 and its significance in laryngeal squamous cell carcinoma (LSCC). Methods: The expression levels of KAI1/CD82 and MRP1/CD9 in 100 LSCC tissue specimens, as well as in 30 para-LSCC non-carcinomatous tissue specimens randomly taken from the patients, were assessed using the quantitative polymerase chain reaction (Q-PCR) and immunohistochemistry and correlations with pathological parameters of LSCC and their influence on survival function were analyzed. Results: KAI1/CD82 and MRP1/CD9 showed basically consistent changes in both mRNA and protein expression. Their expression in the 30 LSCC specimens was significantly lower compared with that in the corresponding non-carcinous tissues (P < 0.01 or 0.05), notably correlating with TNM stage, differentiation degree, clinical stage, and lymphatic metastasis (P < 0.01 or 0.05), but not gender, age, and LSCC growth sites (P > 0.05). The median survival of patients with positive KAI1/CD82 and MRP1/CD9 protein expression was longer than that of patients with negative protein expression (P < 0.01 or 0.05). KAI1/CD82 protein expression negatively correlated with MRP1/CD9 protein expression in LSCC (${\chi}^2$= 31.25, P < 0.01). Conclusion: KAI1/CD82 and MRP1/CD9 may jointly participate in the development of LSCC. They may serve as the markers for judging the infiltration, metastasis, and prognosis of LSCC.

Influences of Freezing and Thawing Temperature on the Quality Characteristics of Mashed Red Pepper (냉해동 온도에 따른 마쇄 홍고추의 품질특성 변화)

  • Hwang, In-Guk;Jeong, Heon-Sang;Lee, Jun-soo;Kim, Hae-Young;Yoo, Seon-Mi
    • The Korean Journal of Food And Nutrition
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    • v.25 no.3
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    • pp.691-696
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    • 2012
  • We conducted this study to investigate the quality characteristics of mashed red pepper(MRP) with different freezing(-20, -30, -40, -50, -60 or $-70^{\circ}C$) and thawing(4, 10, 20, 30, 40 or $50^{\circ}C$) temperature. Frozen and thawed MRP was evaluated for ascorbic acid contents(AsA), capsaicinoids contents, free sugar contents, ASTA value, and flavor patterns. The AsA of frozen MRP with freezing temperature showed a range of 67.08~80.35 mg/100 g FW, and the mean AsA losses after frozen were 57~64% compared to raw red pepper. Capsaicinoids contents, free sugar contents, and ASTA values of frozen MRP with freezing temperature were no significant difference compared to raw red pepper. The AsA of thawed MRP with thawing temperature showed a range of 70.34~81.59 mg/100 g FW, and the mean AsA losses after thawed were 45.12~52.69% compared to raw red pepper. Capsaicinoids contents and free sugar contents of thawed MRP with thawing temperature were no significant difference compared to raw red pepper, whereas the ASTA value decreased according to the increasing of thawing temperature. Flavor patterns of thawed MRP after $20{\sim}50^{\circ}C$ thawing were clearly different from the raw red pepper. Overall, it is recommended that the best freezing and thawing temperature for preserving the quality of MRP is freezing at $-20^{\circ}C$ and thawing at $10^{\circ}C$.

Simple Signal Reconstruction by Faster Adaptive MRP Algorithm (고속 적응 MRP 알고리즘에 의한 저주파 신호 복원)

  • Jeong, Won-Yong;Kim, Jong-Su;Choe, Tae-Won;Bae, Jin-Ho
    • The Journal of the Acoustical Society of Korea
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    • v.11 no.2
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    • pp.5-14
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    • 1992
  • In the fields of astronomy, communication, X-ray crystallography, and engineering, it is a very important and useful fact that the original signal can be reconstructed from a partial information, only spectral magnitude or phase, of the signal. In this paper, we proposed a modified iterative algorithm to solve the Magnitude Retrieval Problem (MRP) for 1-D, 2-D signals. In oder to accelerate the convergence rate, the unit constant initial function which is used in the references is replaced by the exponential initial function for the modified adaptive iterative method. As a result, MRP with 1-D signal and low-pass detail image is significantly enhanced from an iterative convergence rate and a computer storage memory points of view.

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A Study on the Implementation of Distributed MRP to Increase the Utilization of the MES System in the Automobile Parts Manufacturing Industry (자동차부품 제조업의 MES 시스템 활용도를 높이기 위한 분산형 MRP 구현에 관한 연구)

  • Nam, Eun-Jae;Kim, Kwang-Soo
    • Journal of the Korea Safety Management & Science
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    • v.24 no.2
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    • pp.127-134
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    • 2022
  • Production management in the automobile parts industry is carried out according to the production plan of the customer, so it is important to prevent shortages in product supply. As the product composition became increasingly complex, the MES System was built for the purpose of efficient production plan management and inventory management, but its utilization is low. This study analyzed the problems of the MES system and sought to improve it. Through previous studies, it was confirmed that the inventory management of the pull approach that actually occurred in the warehouse is more suitable than the push approach based on the forecast of the warehouse for the volatility, complexity, and uncertainty of orders in the auto parts industry. To realize this, we tried distributed MRP by using the ADO function of VBA to link the standard information of the MES system with Excel and change the structure of the BOM table. Through this, it can help increase the accuracy of production planning and realize efficient inventory management, thereby increasing the utilization of the MES system in the auto parts industry and enhancing the competitiveness of the company.

A Control Account Planning Using Material Requirement Planning in Earned Value Project (MRP기법을 이용한 EV프로젝트의 관리계정계획)

  • Kim Soo-Yong;Lee Yang-Ho;An Dong-Geun
    • Korean Journal of Construction Engineering and Management
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    • v.3 no.4 s.12
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    • pp.114-122
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    • 2002
  • Earned Value Management System(EVMS) is a management technique that is emerging as a valuable tool in the management of all projects, including and in particular construction projects. It is based on C/SCSC that has been released by the U.S. Department of Defense (DOD) in 1967. In a project that employs the earned value management concept, the project's measurable performance plans will be formed with the creation of CAPs. The formation of CAPs is a planning step necessary to form an earned value baseline. In this paper, a method is proposed to form CAPs using Material Requirement Planning(MRP) that is also known as a useful planning tool in the manufacturing industry. An application to a real project has been carried through workpackaging model.

A Study on the Work Package and Resource Planning of En by using the Material Requirement Planning(MRP) (MRP기법을 이용한 EVMS의 복합작업$\cdot$자원계획에 관한 연구)

  • Kim Soo-Yong;Lee Yang-Ho;Lee Young-Dae
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.410-415
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    • 2001
  • Earned Value Management System(EVMS) has been considered as a useful tool of managing construction projects lately and its instruction into a private industry is now under consideration by the Korean government. It is on the basis of C/SCSC that had been released by the U.S. Department of Defense(DOD) since 1967. Its research has been in the active progress in order to utilize the earned value concept as a project management tool for construction project ordered by both government and private sector. Material Requirement Planning(MRP) is also known as a tool of planning and scheduling resources for assembly product as a part of inventory control models in the manufacturing industry. The purpose of this study is the effective employment of Earned Value Management to manage the construction projects by utilizing Material Requirement Planning(MRP), based on project management software and Workpackaging model.

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The location of midfacial landmarks according to the method of establishing the midsagittal reference plane in three-dimensional computed tomography analysis of facial asymmetry

  • Kim, Min Sun;Lee, Eun Joo;Song, In Ja;Lee, Jae-Seo;Kang, Byung-Cheol;Yoon, Suk-Ja
    • Imaging Science in Dentistry
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    • v.45 no.4
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    • pp.227-232
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    • 2015
  • Purpose: The purpose of this study was to evaluate the influence of methods of establishing the midsagittal reference plane (MRP) on the locations of midfacial landmarks in the three-dimensional computed tomography (CT) analysis of facial asymmetry. Materials and Methods: A total of 24 patients (12 male and 12 female; mean age, 22.5 years; age range, 18.2-29.7 years) with facial asymmetry were included in this study. The MRP was established using two different methods on each patient's CT image. The x-coordinates of four midfacial landmarks (the menton, nasion, upper incisor, and lower incisor) were obtained by measuring the distance and direction of the landmarks from the MRP, and the two methods were compared statistically. The direction of deviation and the severity of asymmetry found using each method were also compared. Results: The x-coordinates of the four anatomic landmarks all showed a statistically significant difference between the two methods of establishing the MRP. For the nasion and lower incisor, six patients (25.0%) showed a change in the direction of deviation. The severity of asymmetry also changed in 16 patients (66.7%). Conclusion: The results of this study suggest that the locations of midfacial landmarks change significantly according to the method used to establish the MRP.

Flavor Pattern and Sensory Properties of Meat Flavor Based on Maillard Reaction Products with Supercritical Fluid Extracted Lard Fractions (초임계 추출 Lard를 이용한 Maillard 반응생성물 유래 육류향미제의 향기패턴 및 관능적 특성)

  • Moon, Ji-Hye;Choi, In-Wook;Choi, Hee-Don;Kim, Yoon-Sook
    • Food Science of Animal Resources
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    • v.32 no.5
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    • pp.644-651
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    • 2012
  • We have investigated the effect of lard fraction extracted with supercritical carbon dioxide (SC-$CO_2$) on the flavor enhancement of maillard reaction product (MRP) based meat flavors. MRP based meat flavors were prepared with low glutamic acid (Glu) hydrolyzed wheat gluten (NaCl concentration: 7.61%(w/v)), ribose, cysteine, garlic juice powder, protease-digested Lentinus edodes powder and lard fractions extracted with SC-$CO_2$. Lard was extracted with SC-$CO_2$ at each of three temperatures (40, 60, and $80^{\circ}C$) and at each of four pressures (30, 40, 50, and 60 MPa). Obtained lard SC-$CO_2$ fractions and MRP based meat flavors with those fractions were analyzed for their total yield, aroma pattern by SMart nose system, and sensorial properties. The extraction yield had no difference as temperature increased from $40^{\circ}C$ to $60^{\circ}C$ and even decreased at $80^{\circ}C$. However, increase in pressure level at $40^{\circ}C$ drastically increased the extraction yield. The aroma patterns of raw lard and lard SC-$CO_2$ fractions with 30 MPa were significantly discriminated from those of SC-$CO_2$ lard fractions extracted with higher pressure by SMart nose system. Aroma pattern of MRP based meat flavors with higher pressure extracted lard fractions also showed significant difference through pattern analysis by the SMart nose system. The MRP based meat flavor with lard SC-$CO_2$ fractions at 50 and 60 MPa were described as less sulfuric, less pungent, and more balanced in roasted meat and sweet attributes from sensory evaluation.

동적인 제조환경에서의 유연한 생산 스케줄링을 위한 TOC/JIT/MRP 통합 모델에 관한 연구

  • Ji, Yeong-Ju
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2004.05a
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    • pp.383-386
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    • 2004
  • 급변하는 시장환경으로 인한 제조의 복잡성과 동적 특성의 증대로 인해 기업은 재공품의 감소, 납기일 준수를 위한 기술적 방법의 개발과 조화의 중요성을 인식하고 있다. 이에 기존에 사용하고 있는 MRP, JIT의 생산계획 및 통제 방식은 적용하는 데 있어 단점을 지니고 있다. 이에 최근 각광 받고 있는 TOC의 DBR 방식을 이해하고 기존 생산시스템(MRP, JIT)의 단점을 극복하고 동적인 생산환경에서도 효율적으로 생산 가능한 유연한 생산 스케줄링 모델을 개발하고자 한다. 개발된 생산 스케줄링 모델은 동적인 제조환경에서 효율적이고 유연한 생산 계획 및 통제 시스템이 될 것이며, 비용절감과 함께 기업의 생산성을 향상시킬 것이다. 또한, 이런 유연 생산 스케줄링을 증명하기 위해 프로토타입을 통해 그 효과를 증명하여 보기로 한다.

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ATM Traffic Modeling with Markov Renewal Process and Performance Analysis (마코프 재생과정을 이용한 ATM 트랙픽 모델링 및 성능분석)

  • Jeong, Seok-Yun;Hur, Sun
    • Journal of the Korean Operations Research and Management Science Society
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    • v.24 no.3
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    • pp.83-91
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    • 1999
  • In order to build and manage an ATM network effectively under several types of control methods, it is necessary to estimate the performance of the equipments in various viewpoints, especially of ATM multiplexer. As for the method to model the input stream into the ATM multiplexer, many researches have been done to characterize it by, such as, fluid flow, MMPP(Markov Modulated Poisson Process), or MMDP (Markov Modulated Deterministic Process). We introduce an MRP(Markov Renewal Process) to model the input stream which has proper structure to represent the burst traffic with high correlation. In this paper, we build a model for aggregated heterogeneous ON-OFF sources of ATM traffic by MRP. We make discrete time MR/D/1/B queueing system, whose input process is the superposed MRP and present a performance analysis by finding CLP(Cell Loss Probability). A simulation is done to validate our algorithm.

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