• Title/Summary/Keyword: modular components

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Gene annotation by the "interactome"analysis in KEGG

  • Kanehisa, Minoru
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2000.11a
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    • pp.56-58
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    • 2000
  • Post-genomics may be defined in different ways depending on how one views the challenges after the genome. A popular view is to follow the concept of the central dogma in molecular biology, namely from genome to transcriptome to proteome. Projects are going on to analyze gene expression profiles both at the mRNA and protein levels and to catalog protein 3D structure families, which will no doubt help the understanding of information in the genome. However complete, such catalogs of genes, RNAs, and proteins only tell us about the building blocks of life. They do not tell us much about the wiring (interaction) of building blocks, which is essential for uncovering systemic functional behaviors of the cell or the organism. Thus, an alternative view of post-genomics is to go up from the molecular level to the cellular level, and to understand, what I call, the "interactome"or a complete picture of molecular interactions in the cell. KEGG (http://www.genome.ad.jp/kegg/) is our attempt to computerize current knowledge on various cellular processes as a collection of "generalized"protein-protein interaction networks, to develop new graph-based algorithms for predicting such networks from the genome information, and to actually reconstruct the interactomes for all the completely sequenced genomes and some partial genomes. During the reconstruction process, it becomes readily apparent that certain pathways and molecular complexes are present or absent in each organism, indicating modular structures of the interactome. In addition, the reconstruction uncovers missing components in an otherwise complete pathway or complex, which may result from misannotation of the genome or misrepresentation of the KEGG pathway. When combined with additional experimental data on protein-protein interactions, such as by yeast two-hybrid systems, the reconstruction possibly uncovers unknown partners for a particular pathway or complex. Thus, the reconstruction is tightly coupled with the annotation of individual genes, which is maintained in the GENES database in KEGG. We are also trying to expand our literature surrey to include in the GENES database most up-to-date information about gene functions.

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Development and Application of Process Model for Description of Load Change of Boiler Plant in High Load (고부하에서의 보일러 플랜트 부하변동 묘사를 위한 프로세스 모델 개발 및 적용)

  • Park, Jeong;Lee, Ki-Hyun;Yang, Li-Ming;In, Jong-Soo;Park, Seok-Ho;Kweon, Sang-Hyeok;Oh, Dong-Han
    • Journal of Energy Engineering
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    • v.6 no.1
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    • pp.41-51
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    • 1997
  • A dynamic mathematical model of a thermal power plant with a single drum-type boiler is described with the base on modular concept. The present process model, which is including full scope of the components and high load changes, is based on physical approach through lumped parameters. The module, which means a component of the power plant and must essentially depict the characteristics of the component well, might be interconnected using pressure nodal method in a arrangement determined by users. With the results of the load changes of 75 MW to 95 MW and 95MW to 75 MW with the rate of 3 MW/min, the applicability of the process model is examined connecting to DCS(Dispersion Control System), which has a real running logic of 100 MW real power plant.

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A Study of MMS Computer Program for Dynamic Analysis of Power Plant (발전소 동적 성능분석에 관한 연구)

  • 홍용표;곽병엽;윤명열
    • Journal of Energy Engineering
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    • v.2 no.1
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    • pp.28-37
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    • 1993
  • This paper describes the development of a dynamic model of 1,000 MW$\_$e/ nuclear power plant including its local and integrated control system. The model was constructed using the Modular Modeling System (MMS) developed by the Electric Power Research Institute (EPRI) to provide an efficient, economical and user-friendly computer code for use in the analysis of the dynamic performance of nuclear and fossil power plants in conjunction with the Advanced Continuous Simulation Language (ACSL). Steady state for full load and transient results for turbine power step changes of loft are presented in this paper. The model includes most major components of a 1,000 MW$\_$e/ nuclear power plant and it can readily be modified to simulate a specific power plant. This procedure greatly reduces the analysis and modeling efforts involved in dynamic simulation of power plants and increases confidence in the analysis results.

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Development of Automatic Design Program for Solid Rocket Motors Structure (고체 추진기관 구조체의 설계 자동화 프로그램 개발)

  • Kim, Won-Hoon;Koo, Song-Hoe;Moon, Soon-Il;Hwang, Ki-Young;Lee, Kang-Soo;Seok, Jung-Ho
    • Journal of the Korean Society of Propulsion Engineers
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    • v.10 no.3
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    • pp.18-25
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    • 2006
  • In order to perform system requirements quickly and accurately, an automatic design program of solid rocket motors(SRM) structure designated as the 'ProDes software' has been developed and verified. from given system design criteria and constraints, it has the capabilities to design, analysis, simulation and drawing process to greatly reduce the over 'design cycle time' and manpower of a project. The conception of the program is modular, and calculations are performed step by step allowing parametric design studies and providing final selected design goal. Each configurations of SRM components and joint types composed of various master models is obtained from the data base module of the library. Between the design results of the ProDes software and those of the previous detail design of the established motor showed good agreements.

The Study of Web Services Adaptation in IPv6/IPv4 Coexistence Network (IPv6/IPv4 공존 환경에서의 웹서비스 적용에 관한 연구)

  • Lee, Won-Suk;In, Min-Kyo;Lee, Seung-Yun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • v.9 no.1
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    • pp.747-749
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    • 2005
  • The popularity of web services within the IT industry continues to grow as the next generation web technologies. Web services are self-contained, self-describing, modular applications that can be published, located, and invoked across the Web. Web services will be core technology for e-business in the Web. IPv6 is sometimes also called the Next Generation Internet Protocol and is a new version of IP which is designed to be an evolutionary step from IPv4. In this paper, we define problems for adapting web services to IPv6 Environment. This paper survey and explain consideration issues that include standards, components, coexistence of IPv6 and IPv4, etc.

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Automatic Combination & Assembly System for Phone Camera Lens Module (폰 카메라 렌즈모듈 자동 조합시스템 개발)

  • Song, Jun Yeob;Ha, Tae Ho;Lee, Chang Woo;Kim, Dong Hoon;Jeon, Jong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.2
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    • pp.219-225
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    • 2014
  • An automatic combination and assembly system for phone-camera lens modules was developed. The system enables the assembly of the relative orientation of the individual lenses making up the lens module. Conventional assembly systems assemble a lens module from eight assembly units. The developed system reduces this number to half by combining each lens and a spacer into a single assembly unit. Also, the number of transfer stages for sequential assembly is minimized without increasing the assembly time. Therefore, high productivity and a footprint that is only about 25 % of that of a conventional assembly system can be realized. The system features a modular design to allow it to cope with rapid changes in the market. Only a few components, such as the picker and guide, need to be replaced for changing to a new assembly model.

Evaluation of Three Support Shapes on Behavior of New Bolted Connection BBCC in Modularized Prefabricated Steel Structures

  • Naserabad, Alifazl Azizi;Ghasemi, Mohammad Reza;Shabakhty, Naser;Arab, Hammed Ghohani
    • International journal of steel structures
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    • v.18 no.5
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    • pp.1639-1653
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    • 2018
  • Bolted connections are suitable due to high quality prefabrication in the factory and erection in the workplace. Prefabrication and modularization cause high speed of erection and fabrication, high quality and quick return of investment. Their technical hitches transportation can be removed by prefabrication of joints and small fabrication of components. Box-columns are suitable members for bolted structures such as welded steel structures with moment frames in two directions etc., but their continual fabrication in multi-story buildings and performing the internal continuity plate in them will cause some practical dilemmas. The details of the proposal technique introduced here, is to remove such problems from the box columns. Besides, some other advantages include new prefabricated bolted beam-to-column connections referred to BBCC. This connection is a set of plates joined to columns, beams, support, and bolts. For a better understanding of its fabrication and erection techniques, two connection and one structural maquettes are made. The present work aims to study the cyclic behavior of connection numerically. To verify the accuracy of model, a similar tested connection was modelled. Its verification was then made through comparison with test results. The behavior of connection was evaluated for an exterior connection using three different support shapes. The effects of support shapes on rigidity, ductility, rotation capacity, maximum strength, four rad rotation strength were compared to those of the AISC seismic provision requirements. It was found that single beams support has all the AISC seismic provision requirements for special moment frames with and without a continuity plate, and box with continuity plate is the best support in the BBCC connection.

A Study on Accelerated Corrosion Rate of Stainless Steel Type 630 with Increasing Temperature of B-free Alkaline Coolant (무붕산 알칼리 냉각재 온도 증가에 따른 Type 630 스테인리스강의 부식특성 평가 연구)

  • Jeongsoo Park;Sang-Yeob Lim;Soon-Hyeok Jeon;Ju-Seong Kim;Jeong-Mok Oh;Hee-Sang Shim
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.20 no.1
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    • pp.49-55
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    • 2024
  • Stainless 630 (or 17-4PH) is a precipitation-hardening martensitic stainless steel that has excellent mechanical properties and corrosion resistance. These characteristics make the STS630 to be used as a consisting material for various components such as spider, pin, spring, and spring retainer, of the control rod drive mechanism (CRDM) in pressurized water reactors (PWRs). In general, it is well known that the oxide layer of stainless steel consists of a duplex layer, a compact inner layer of FeCr2O4 spinel, and a coarse-grained outer layer of Fe3O4 spinel in PWR primary coolant condition. However, the characteristics of the oxide layer can be sensitively influenced by various water chemistry conditions such as temperature, dissolved oxygen, dissolved hydrogen, pH, pH adjuster type, and exposure time. In this work, we investigate the corrosion properties of the STS630 as a function of coolant temperature in an NH3 alkaline solution for its boron-free application in a small modular reactor, to confirm the feasibility for usage as a boron-free SMR structural material. As a result, oxide layer of corroded STS630 is consist of double-layer oxides consisting of a Cr-rich dense inner oxide and a Fe-rich polyhedral outer particles like as that in commercial PWR primary coolant. The corrosion rate of STS630 increases with increase in test time and temperature and the corrosion rate-time model equation was developed based on experimental data. Overall, it is expected that the results in this study provides useful data for the corrosion behavior of STS630 in alkaline environments, contributing to the development of selecting suitable materials for SMRs.

Multiple Case Analysis Study on Business Model Types and Components of Startups: Focusing on Leading Overseas Smart Farm Companies (스타트업의 비즈니스 모델 유형 및 구성요소에 대한 다중 사례 분석 연구: 해외 스마트팜 선도기업을 중심으로)

  • Ahn, Mun Hyoung
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.18 no.6
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    • pp.41-55
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    • 2023
  • In order to secure sustainable competitiveness of startups, business model innovation is an important task to achieve competitive advantage by transforming the various elements that make up the business model. This study conducted a multi-case analysis study on leading smart farm companies around the world using an analysis framework based on business model theory. Through this, we sought to identify business model types and their constituent elements. For this, 19 companies were selected from the list of top 10 investment startups of the year for the past three years published by Agfunder, a global investment research company specializing in AgTech. Then data collection and analysis of the company cases were conducted according to the case study protocol. As a result of the study, the business model types were analyzed into four types: large-scale centralized production model, medium-to-large local distributed production model, small-scale hyperlocal modular FaaS model, and small-scale hyperlocal turnkey solution supply model. A comparative analysis was conducted on five business model components for each type, and strategic implications were derived through this. This study is expected to contribute to improving the competitiveness of domestic smart farm startups and diversifying their strategies by identifying the business models of overseas leading companies in the smart farm field using an academic analysis framework.

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A Scalable and Modular Approach to Understanding of Real-time Software: An Architecture-based Software Understanding(ARSU) and the Software Re/reverse-engineering Environment(SRE) (실시간 소프트웨어의 조절적${\cdot}$단위적 이해 방법 : ARSU(Architecture-based Software Understanding)와 SRE(Software Re/reverse-engineering Environment))

  • Lee, Moon-Kun
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.12
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    • pp.3159-3174
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    • 1997
  • This paper reports a research to develop a methodology and a tool for understanding of very large and complex real-time software. The methodology and the tool mostly developed by the author are called the Architecture-based Real-time Software Understanding (ARSU) and the Software Re/reverse-engineering Environment (SRE) respectively. Due to size and complexity, it is commonly very hard to understand the software during reengineering process. However the research facilitates scalable re/reverse-engineering of such real-time software based on the architecture of the software in three-dimensional perspectives: structural, functional, and behavioral views. Firstly, the structural view reveals the overall architecture, specification (outline), and the algorithm (detail) views of the software, based on hierarchically organized parent-chi1d relationship. The basic building block of the architecture is a software Unit (SWU), generated by user-defined criteria. The architecture facilitates navigation of the software in top-down or bottom-up way. It captures the specification and algorithm views at different levels of abstraction. It also shows the functional and the behavioral information at these levels. Secondly, the functional view includes graphs of data/control flow, input/output, definition/use, variable/reference, etc. Each feature of the view contains different kind of functionality of the software. Thirdly, the behavioral view includes state diagrams, interleaved event lists, etc. This view shows the dynamic properties or the software at runtime. Beside these views, there are a number of other documents: capabilities, interfaces, comments, code, etc. One of the most powerful characteristics of this approach is the capability of abstracting and exploding these dimensional information in the architecture through navigation. These capabilities establish the foundation for scalable and modular understanding of the software. This approach allows engineers to extract reusable components from the software during reengineering process.

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