• Bulletin of the Korean Chemical Society
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• v.28 no.12
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• pp.2377-2381
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• 2007

Solvolyses of 3,4-dimethoxybenzenesulfonyl chloride (DSC) in water, D2O, CH3OD, and in aqueous binary mixtures of acetone, acetonitrile, 1,4-dioxane, ethanol, methanol, and 2,2,2-trifluoroethanol (TFE) have been investigated at 25.0 oC. Kinetic solvent isotope effects (KSIE) in water and in methanol and product selectivities in alcohol-water mixtures are also reported. The Grunwald-Winstein plot of first-order rate constants for the solvolyic reaction of DSC with YCl shows marked dispersions into separated lines for various aqueous mixtures. With use of the extended Grunwald-Winstein equation, the l and m values obtained are 1.12 and 0.58 respectively for the solvolyses of DSC. The relatively large magnitude of l is consistent with substantial nucleophilic solvent assistance. From Grunwald-Winstein plots the rate data are dissected approximately into contributions from two competing reaction channels. This interpretation is supported for alcohol-water mixtures by the trends of product selectivities, which show a maximum for ethanol-water mixtures. From the KSIE of 1.45 in methanol, it is proposed that the reaction channel favored in methanolwater mixtures and in all less polar media is general-base catalysed and/or is possibly (but less likely) an addition-elimination pathway. Also, the KISE value of 1.35 for DSC in water is expected for SN2-SN1 processes, with minimal general base catalysis, and this mechanism is proposed for solvolyses in the most polar media.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.605-608
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• 2008

This study investigated fundamental properties corresponding to mixtures for the high strength, and their properties of spalling prevention after a fire test. The results were summarized as following. For the flowability of using mixtures for the high strength, the target flow was satisfied with a small quantity of high performance reducing water agent to compare with silica fume. For the compressive strength in the case of using mixtures for the high strength, it was higher to compare with silica fume at 7 days, so it was proved that using mixtures for the high strength was profitable to prevent early frost damage. The compressive strength at the 28 days of silica fume and mixtures for the high strength were similar. There was no reduced tendency at the compressive strength according fiber contents, so it found out that the bonding strength between the fiber and concrete was hardly effective. For the spalling properties, the specimens without fibers were destroyed, however using over 0.05% of NY and PP fibers was effective to prevent spalling on the high strength concrete.

• Preventive Nutrition and Food Science
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• v.14 no.3
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• pp.233-239
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• 2009

The effects of guar gum (GG) and xanthan gum (XG) at different concentrations (0, 0.2, 0.4, and 0.6% w/w) on the rheological properties of Korean waxy rice starch (WRS) pastes were evaluated under both steady and dynamic shear conditions. The flow properties of WRS-gum mixtures were determined from the rheological parameters of the power law model. The addition of GG and XG to WRS resulted in an increase in the apparent viscosity ($\eta_{a,100}$) and consistency index (K) values obtained from power law model. The flow behavior index (n) values of the WRS-XG mixtures decreased with an increase in gum concentration while there was only a marginal difference between n values for the WRS-GG mixtures. Dynamic moduli (G', G", and $\eta^*$) values in the WRS-gum mixture systems also increased with an increase in gum concentration. WRS-XG mixtures had higher dynamic moduli and lower tan $\delta$ (ratio of G"/G') values than WRS-GG mixtures, indicating that the higher dynamic rheological properties of WRS-XG can be attributed to an increase in the viscoelasticity of the continuous phase in the starch-gum mixture systems, which was due to the higher viscoleastic properties of XG compared to GG. The dynamic ($\eta^*$) and steady shear ($\eta_a$) viscosities of the WRS-XG paste at a 0.2% gum concentration followed the Cox-Merz superposition rule.

• The Korean Journal of Community Living Science
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• v.18 no.3
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• pp.407-415
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• 2007

The aim of this study was to investigate the physiological functionalities of Codonopsis lanceolata, Glycyrrhiza uralensis, Chaenomeles sinensis, Crataegus pinnafida, and their mixtures. We also determined their antioxidative, fibrinolytic, and ${\alpha}-glucosidase$ inhibitory activities. The antioxidative activities of Codonopsis lanceolata, Glycyrrhiza uralensis, Chaenomeles sinensis, and Crataegus pinnafida were 79%, 88.3%, 89.9%, and 89.3% respectively. Their fibrinolytic activities were 0.80plasmin unit/mi, 0.57 plasmin unit/mi, 0.52 plasmin unit/mi, and 0.53 plasmin unit/mi respectively. The ${\alpha}-glucosidase$ inhibitory activity of Codonopsis lanceolata was 25%. The 10-fold diluents of Glycyrrhiza uralensis, Chaenomeles sinensis, and Crataegus pinnafida showed ${\alpha}-glucosidase$ inhibitory activities of 93.6%, 65.3%, and 61.3% respectively. In antioxidative activity tests of the medicinal plants mixtures at various ratios, the mixtures of Glycyrrhiza uralensis, Chaenomeles sinensis, and Crataegus pinnafida with Codonopsis lanceolata showed antioxidative activities of approximately 90%. In fibrinolytic activity tests mixtures(1:1) of Codonopsis lanceolata with Chaenomeles sinensis and Crataegus pinnafida exhibited increases of 23% and 24% in activity respectively. In ${\alpha}-glucosidase$ inhibitory activity tests, a mixture (4:1) of Codonopsis lanceolata and 10-fold diluted Glycyrrhiza uralensis showed an inhibitory activity of 98%, a mixture (3:1) of Codonopsis lanceolata and 10-fold diluted Chaenomeles sinensis showed an inhibitory activity of 69.6%, and a mixture (1:1) of Codonopsis lanceolata and 10-fold diluted Crataegus pinnafida showed an inhibitory activity of 50.2%. In conclusion, the mixtures of Glycyrrhiza uralensis, Chaenomeles sinensis, and Crataegus pinnafida with Codonopsis lanceolata will be used as a material for the development of biofunctional foods.

• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.2
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• pp.75-80
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• 2020

In this study, we investigated the dose-dependent effects of mixtures of Atractylodes macrocephala (AM) and Amomum villosum (AV) water extracts in a ratio of 3:1 on high fat diet (HFD)-induced obesity model. Oral administration of various concentrations with mixtures of AM and AV extracts in a ratio of 3:1 for 6 weeks inhibited HFD-induced increases of body, liver and epididymal fat weights in a dose-dependent fashions. Those effects may be mediated by decreased expressions of lipogenesis-related genes such as acetyl coA carboxylase (ACC) and fatty acid synthase (FAS) in liver. Also, increase of insulin and decrease of adiponectin in serum by HFD supply were inhibited by three different dosages of mixtures of AM and AV extracts in a ratio of 3:1. HFD supply induced increases of serum total cholesterol, triglyceride and LDL cholesterol. However, hyperlipidemia was significantly decreased in dose-dependent manners by treatment with mixtures of AM and AV extracts. Based on the results of the present study, hypolipidemic and anti-obesity effects by mixtures of AM and AV extracts were found in HFD-induced obesity model. Further clinical investigation is needed to develop anti-obesity therapeutic or preventive agents by using mixtures of AM and AV extracts.

• Bulletin of the Korean Chemical Society
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• v.35 no.12
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• pp.3637-3641
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• 2014

In this study, we analyzed the toxicity of mixtures of dimethylformamide (DMF) and methyl ethyl ketone (MEK) or DMF and toluene (TOL) and predicted their toxicity using quantitative structure-activity relationships (QSAR). A QSAR model for single substances and mixtures was analyzed using multiple linear regression (MLR) by taking into account the statistical parameters between the observed and predicted $EC_{50}$. After preprocessing, the best subsets of descriptors in the learning methods were determined using a 5-fold cross-validation method. Significant differences in physico-chemical properties such as boiling point (BP), specific gravity (SG), Reid vapor pressure (rVP), flash point (FP), low explosion limit (LEL), and octanol/water partition coefficient (Pow) were observed between the single substances and the mixtures. The $EC_{50}$ of the mixture of DMF and TOL was significantly lower than that of DMF. The mixture toxicity was directly related to the mixing ratio of TOL and MEK (MLR $EC_{50}$ equation = $1.76997-1.12249{\times}TOL+1.21045{\times}MEK$), as well as to SG, VP, and LEL (MLR equation $EC_{50}=15.44388-19.84549{\times}SG+0.05091{\times}VP+1.85846{\times}LEL$). These results show that QSAR-based models can be used to quantitatively predict the toxicity of mixtures used in manufacturing industries.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.4 no.2
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• pp.123-136
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• 1992

A preliminary thermodynamic design model of two-evaporator refrigerator/freezer system is constructed. This system is based on Lorentz-Meutzner cycle using refrigerant mixtures. This model screens alternative refrigerant (R32, R125, R143a, R22, R134a, R152a, R124, R142b, R123) mixtures to select the best performance-giving refrigerant mixtures and its composition for the system. Also, it estimates the effects of cooling temperatures of intercoolers, evaporator's area ratio, cooling load ratio on the performance of the system. The COP of the system ranges from 1.4 to 1.6, which is superior to that of the single evaporator system charged with R12 by 13% to 29%. Among 15 mixtures, R22/R123, R143a/R123, R32/R142b, and R32/R124 (in the order of high COP) are most recommendable. For the case of R22/R123, R22 mass fraction more than 0.5(Load Ratio=1.0) or 0.7(Load Ratio=0.33) is recomended in order to replace R12 without reduction in volumetric capacity when keeping the compressor as the same one. COP has the highest value with X(R22)=0.7 and 0.8, respectively. For the case of R143a/R123, in the similar manner, mass fraction of R143a is more than 0.5 or 0.6 while best performance occurs at X(R143a)=0.8. Higher temperature intercooler is more important for the performance of the system than lower temperature intercooler. The area ratio of evaporators is roughly proportional to load ratio of the evaporators.

• Geomechanics and Engineering
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• v.15 no.1
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• pp.659-668
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• 2018

A series of direct shear tests were implemented on three different types of specimens (i.e., clean Perth sand, sand containing 10, 20 and 30% bentonite, sand containing 1, 3 and 5% slag, and sand containing 10, 20 and 30% bentonite with increasing percentages of added slag (1%, 3% and 5%). This paper focuses on the shear stress characteristics of clean sand and sand mixtures. The samples were tested under different three normal stresses (100, 150 and 200 kPa) and three curing periods of no curing time, 7 and 14 days. It was observed that the shear stresses of clean sand and mixtures were increased with increasing normal stresses. In addition, the use of slag has improved the shear strength of the sand-slag mixtures; the shear stresses rose from 128.642 kPa in the clean sand at normal stress of 200 kPa to 146.89 kPa, 154 kPa and 161.14 kPa when sand was mixed with 1%, 3% and 5% slag respectively and tested at the same normal stress. Internal friction angle increased from $32.74^{\circ}$ in the clean sand to $34.87^{\circ}$, $37.12^{\circ}$ and $39.4^{\circ}$ when sand was mixed with 1%, 3% and 5% slag respectively and tested at 100, 150, and 200 kPa normal stresses. The cohesion of sand-bentonite mixtures increased from 3.34 kPa in 10% bentonite to 22.9 kPa, 70.6 kPa when sand was mixed with 20% and 30% bentonite respectively. All the mixtures of clean sand, different bentonite and slag contents showed different behaviour; some mixtures exhibited shear stress more than clean sand whereas others showed less than clean sand. The internal friction angle increased, and cohesion decreased with increasing curing time.

• Korean Chemical Engineering Research
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• v.55 no.4
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• pp.520-529
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• 2017

Viscosity data were measured at 298.15 K and 308.15 K for formamide + 1-propanol, 2-propanol, 1-butanol, 2-methyl-1-propanol or 2-methyl-2-propanol mixtures. For an equimolar mixture, deviation in viscosity follows the sequence: 2-methyl-2-propanol >2-methyl-1-propanol>1-butanol>2-propanol>1-propanol. The viscosity data were further analyzed in terms of graph theory. Free energy of activation was also calculated from experimental viscosity data along with previously reported excess volume data. The deviation in viscosity and free energy of activation were fitted to Redlich-Kister polynomial equation. The viscosity data were also correlated by correlations like Grunberg-Nissan, Tamura-Kurata, HindMcLaughlin-Ubbelohde, and Katti-Chaudhari relation. Various adjustable parameters, $G_{12}$, $T_{12}$, $H_{12}$, and $W_{vis}/RT$, of various correlations were used to predict viscosity deviation of binary mixtures. Positive value of $G_{12}$ indicates strong interaction in the studied systems. Grunberg-Nissan relation has lowest deviation among the four correlations for formamide + 1-propanol or 2-propanol mixtures; and for mixtures of formamide with 1-butanol or 2-methyl-1-propanol, TamuraKurata has lowest deviation. Grunberg-Nissan gives lowest deviation for formamide + 2-methyl-2-propanol mixtures.

• Korean Chemical Engineering Research
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• v.58 no.2
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• pp.257-265
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• 2020

Densities (ρ) for binary mixtures of ethanol (1) + diisopropyl ether (DIPE) or cyclohexane or alkane (C₆-C₉) (2) were measured at 298.15 K, 308.15 K and 318.15 K. The excess molar volume (V^E_m) of binary mixtures was calculated using ρ data and correlated with Redlich-Kister polynomial equation. The V^E_m values for binary mixtures of ethanol (1) + cyclohexane or n-alkane (C₆-C₉) (2) were positive, whereas for ethanol (1) + DIPE (2) these were negative. The magnitude of V^E_m values follows the order: cyclohexane > n-nonane > n-octane > n-heptane > n-hexane > DIPE. The V^E_m values have been interpreted qualitatively and also quantitatively in terms of Flory-Treszczanowicz-Benson (FTB) model and Prigogine-Flory-Patterson (PFP) theory. The values V^E_m predicted using FTB model agree well with experimental V^E_m values at all mole fractions. But the PFP theory describes well V^E_m data in ethanol-rich region (x₁ > 0.5) for all binary mixtures and is able to predict the sign of V^E_m vs x₁ curve for ethanol-lean region (x₁ < 0.5) except for ethanol (1) + nonane (2) mixtures.