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Effects of Fructus Amomi Amari, Eucommiae Cortex, Bombyx Batryticatus Extract on Improving Symptoms of Late-onset Hypogonadism (익지인(益智仁), 두충(杜沖), 백강잠(白殭蠶) 혼합추출물이 남성갱년기 증상 개선에 미치는 영향)

  • Park, Sun Young;Ahn, Sang Hyun;Kim, Ho Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.33 no.2
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    • pp.89-101
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    • 2019
  • In recent times, the number of men with late-onset hypogonadism has increased, and interest on this topic has also increased. This study was conducted to investigate effects of the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus on improve late-onset hypogonadism. The experimental subjects consisted of three groups: a control group consisting of 8-week-old male ICR mice that had undergone no treatment, an aging-elicited group (AE group) consisting of 50-week-old ICR male mice that had undergone no treatment, and a Mixed herbal extract treatment group (MT group) consisting of 50-week-old ICR male mice that had undergone the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus treatment (0.1 g/kg/day) for 6 months. After the experiment, the mice from all the experimental groups were dissected, and they were analyzed through histochemical and immunohistochemical methods. The mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus reduces aging-induced cell damage and oxidative stress and increases the secretion of serotonin and B-endorphin in aged mice, and promotes spermatogenesis in seminiferous tubules and reduces apoptosis and oxidative stress, and increases androgen receptor, $17{\beta}-HSD$ and GnRH, increases the ratio of smooth muscle to collagen fibers in the corpus cavernosum, increases eNOS, decreases PDE-5 and oxidative stress in aged mice, so it improves depression, reproductive, sexual problems caused by Late-onset hypogonadism. the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus inhibits the induction of osteoporosis by increasing decreased bone matrix distribution due to aging, increasing the activities of OPC and OPN, which are produced in osteoblasts, and decreasing RANKL, MMP-3 activity, increasing OPG activity. It also reduces muscle damage, oxidative stress, inflammation and apoptosis of muscle tissue, and increases Myo-D in the sartorius muscle of aged mice for improving muscle atrophy caused by by Late-onset hypogonadism.

Effect of Bundling Strategy on Tourists' Evaluation of Tour Packages (여행 패키지의 묶음판매 전략에 관한 연구)

  • Kim, Seung Lee;Lee, Dong Hee
    • International Area Studies Review
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    • v.16 no.1
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    • pp.53-74
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    • 2012
  • The bundling of multiple products/services at a set price has become a popular marketing strategy. However, little is known on how effects of bundling strategy influence tourists' evaluation of tour packages. Tourists evaluate a tour package based on the trade-off between the perceived benefits and costs involved in purchasing the tour package. In other words, the perceived value of the tour package influenced whether tourists to purchase a tour package or not. This study tested a tour package based on the theory of bundling, taking a moderating approach with perceived value. The data for this study wascollected by subjects who live Seoul Metropolitan Area and Gyeonggi Province and 4234 respondents, potential tourists to northeastern U.S.A/Canada. Results show that bundling taken by travel agencies include how many product items to put in a tour package and what degree of discount for the tour package. Also explaining functional relationship among product items in the tour package. Result show that tourists expect a discount, large or small, from purchasing a tour package. And the larger the number of products in a tour packages, the larger the discount size, and low functional relationship among items tourists expect to get.

Spatiotemporal Traffic Density Estimation Based on Low Frequency ADAS Probe Data on Freeway (표본 ADAS 차두거리 기반 연속류 시공간적 교통밀도 추정)

  • Lim, Donghyun;Ko, Eunjeong;Seo, Younghoon;Kim, Hyungjoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.19 no.6
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    • pp.208-221
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    • 2020
  • The objective of this study is to estimate and analyze the traffic density of continuous flow using the trajectory of individual vehicles and the headway of sample probe vehicles-front vehicles obtained from ADAS (Advanced Driver Assitance System) installed in sample probe vehicles. In the past, traffic density of continuous traffic flow was mainly estimated by processing data such as traffic volume, speed, and share collected from Vehicle Detection System, or by counting the number of vehicles directly using video information such as CCTV. This method showed the limitation of spatial limitations in estimating traffic density, and low reliability of estimation in the event of traffic congestion. To overcome the limitations of prior research, In this study, individual vehicle trajectory data and vehicle headway information collected from ADAS are used to detect the space on the road and to estimate the spatiotemporal traffic density using the Generalized Density formula. As a result, an analysis of the accuracy of the traffic density estimates according to the sampling rate of ADAS vehicles showed that the expected sampling rate of 30% was approximately 90% consistent with the actual traffic density. This study contribute to efficient traffic operation management by estimating reliable traffic density in road situations where ADAS and autonomous vehicles are mixed.

Evaluation of NOx Reduction Performance by Photocatalytic (TiO2) Coating of Cement Mortar Mixed with Zeolite and Activate Hwangtoh (제올라이트와 활성 황토를 혼입한 시멘트 모르타르의 광촉매(TiO2) 코팅에 따른 NOx 저감성능평가)

  • Park, Jang-Hyun;Kim, Hyeok-Jung
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.4
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    • pp.483-489
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    • 2020
  • Particulate matter is divided into PM10 (particle diameter of 10 ㎛ or less) and PM2.5 (particle diameter of 2.5 ㎛ or less), which are approximately 1/5 of the thickness of the hair. Due to its effect on the human body, lung disease, arteriosclerosis and heart It is known as a carcinogen that causes various diseases such as diseases. It is known that the main cause of such fine dust is nitrogen dioxide (NOx), which is emitted from automobiles in about 57.3% of urban roadsides. Therefore, in this study, as part of the development of functional construction materials to reduce NOx generated from road transport pollutants, comparative evaluation of NOx reduction performance was conducted according to the replacement rate of cement mortar in which cement was replaced with a porous material. In addition, the NOx reduction performance of cement mortar according to the photocatalyst application method and the number of applications was compared an d evaluated. As a result of the experiment, when activated ocher was substituted by 30%, it showed a reduction effect of about 32.7%, showing the best reduction performance.

A TBM data-based ground prediction using deep neural network (심층 신경망을 이용한 TBM 데이터 기반의 굴착 지반 예측 연구)

  • Kim, Tae-Hwan;Kwak, No-Sang;Kim, Taek Kon;Jung, Sabum;Ko, Tae Young
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.23 no.1
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    • pp.13-24
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    • 2021
  • Tunnel boring machine (TBM) is widely used for tunnel excavation in hard rock and soft ground. In the perspective of TBM-based tunneling, one of the main challenges is to drive the machine optimally according to varying geological conditions, which could significantly lead to saving highly expensive costs by reducing the total operation time. Generally, drilling investigations are conducted to survey the geological ground before the TBM tunneling. However, it is difficult to provide the precise ground information over the whole tunnel path to operators because it acquires insufficient samples around the path sparsely and irregularly. To overcome this issue, in this study, we proposed a geological type classification system using the TBM operating data recorded in a 5 s sampling rate. We first categorized the various geological conditions (here, we limit to granite) as three geological types (i.e., rock, soil, and mixed type). Then, we applied the preprocessing methods including outlier rejection, normalization, and extracting input features, etc. We adopted a deep neural network (DNN), which has 6 hidden layers, to classify the geological types based on TBM operating data. We evaluated the classification system using the 10-fold cross-validation. Average classification accuracy presents the 75.4% (here, the total number of data were 388,639 samples). Our experimental results still need to improve accuracy but show that geology information classification technique based on TBM operating data could be utilized in the real environment to complement the sparse ground information.

Combustion Characteristics and On-site Performance Test of a Double-cone Partial Premixed Nozzle with Various Fuel hole Patterns (이중 콘형 부분예혼합 GT 연료노즐의 연소특성 및 발전플랜트 실증)

  • Kim, Han Seok;Cho, Ju Hyeong;Kim, Min Kuk;Hwang, Jeongjae;Lee, Won June;Min, Kyungwook;Kang, Do Won
    • Journal of the Korean Institute of Gas
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    • v.25 no.6
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    • pp.22-28
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    • 2021
  • Combustion characteristics were examined experimentally for a swirl-stabilized double cone premixed burner nozzle used for industrial gas turbines for power generation. An original model and a variant with a different fuel injection pattern are tested to compare their combustion characteristics such as NOx, CO and stability in pressurized conditions with single burner-flame and in an ambient multi-flame conditions with multi-burners. Test results show that NOx emissions are smaller for the variant, whose number of fuel holes is reduced with the same total area of fuel holes, in ambient and pressurized single-flame conditions with single burner, which results from enhanced fuel/air mixing due to a higher penetration of fuel into the air stream. The multi-burnerflame test results show that NOx emissions are smaller for the variant due to reduced flame interactions, which, on the contrary, slightly reduces the stability margin. On-site test results fromin an actual power plants also show that NOx emissions are reduced for the variant, compared with the original one, which is in agreement with the lab test results stated above.

Research Trend Analysis according to the Change of "Journal of Korean Elementary Science Education" from 1983 to 2020 ('초등과학교육' 학술지의 변천 과정에 따른 연구 동향 분석(1983~2020년))

  • Shin, Won-sub;Park, Hyoung-Min;Kim, Nam-il
    • Journal of Korean Elementary Science Education
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    • v.40 no.4
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    • pp.545-555
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    • 2021
  • This study aims to analyze research trends by the period of elementary science education journal. A total of 1047 papers were analyzed from Volume 1 No. 1 in 1983 to Volume 39 No. 4 in 2020. The results of the study are as follows: First, the period of elementary science education journals was divided into infancy, settlement, development, and retainment period according to the number of papers. Second, the ratio of research by more than three scholars, pure or funded research was decreasing. Third, the study subjects had a high rate of research on elementary school students and elementary school teachers. Fourth, research methods were mainly research studies and experimental studies, and qualitative analysis and mixed analysis studies were increasing as data analysis methods. Fifth, the occupation of the first author was professor (45.6%), teacher (39.8%), graduate student (10.6%), and researcher (1.7%) in that order. Sixth, the regions of the corresponding author were concentrated in Seoul and Gyeongin, the metropolitan areas. Finally, in order for the "Elementary Science Education" journal to continue to play a pivotal role in leading elementary science education in the future, efforts to improve the overall journal and continuous participation and cooperation of domestic and foreign researchers, academic executives, members, and educational institutions are required.

Substantive Representation of Women Under the Conservative Government in Japan: An analysis of the Diet deliberation of the Bill on Promotion of Women's Participation and Advancement in the Workplace (日本の保守政権下における女性の実質的代表-女性活躍推進法案を巡る国会審議をケースとして)

  • Osawa, Kimiko
    • Analyses & Alternatives
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    • v.5 no.1
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    • pp.87-121
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    • 2021
  • Since 2012, Prime Minister Shinzo Abe'sadministration began to promote women's participation and advancement in the workplace and established the Act on the Promotion of Female Participation and Career Advancement in the Workplace (the Act) in 2015. Some criticize this Act as a way to utilize women for economic development and to deal with the shrinking working population. In contrast, others point out that it is a law that can be beneficial for women. As such, this Act serves as an interesting case of a women's policy promoted by a conservative government. This paper's objective is to shed light on if and how women are substantively represented in the Diet members' statements made during the legislative debate of the bill on the Promotion of Female Participation and Career Advancement in the Workplace between 2014 and 2015. This paper asks two research questions. First, based on the mixed evaluation of the Act made in the studies about the Abe administration's women's policies, this research asks if the Diet members speak of women as resources to use for other economic and social goals or if women are substantively represented. Second, drawing insights from the literature on women's substantive representation, this research asks how Diet members speak for women. Particularly, based on the studies on conservatism and substantive representation of women, this question seeks to determine if Diet members engage in the conservative representation of women, taking women's roles as mothers and wives who provide care for children, husbands, and elders at home for granted. The results of the analysis demonstrate that the number of statements that explicitly claimed to use women was small. Second, while some Diet members of conservative political parties engaged in the conservative representation of women, there were more instances of non-conservative representation, in which a variety of types of women were represented. These findings reveal that even when the conservative government's intention to submit the bill was to utilize women rather than acting for women, Diet members could speak for various types of women and engage in the non-conservative representation of women. The findings also imply the importance of paying attention to formal and informal legislative deliberation rules to figure out how women's substantive representation can occur under a conservative government and in a legislature dominated by conservative parties.

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A Content Analysis of Domestic Research Trends on the Problematic Behavior of Smart Devices in Early Childhood -Focusing on Addiction Proneness- (유아기 스마트기기 사용 문제행동에 대한 국내연구동향 내용분석 -중독경향성을 중심으로-)

  • Kang, Sun-Kyung;Cha, You-Jeong
    • Journal of the Korea Convergence Society
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    • v.12 no.5
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    • pp.217-225
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    • 2021
  • This study analyzed domestic research trends related to the behavior of problems with using smart devices in infants, focusing on addiction tendency. The main results of research trends are as follows: First, the total number of papers published per year is 79, and addiction proneness studies were published in various academic journals, while researchers' major was mostly concentrated in the department of education and social welfare. Second, there were 81 research topics, including actual conditions, scale development, related variables, interventions, and causal relationships. The proportion of research subjects was the highest with 60 (74.1%) research subjects, which are related variables. Third, the subjects of the study were divided into infants, caregivers, and teachers, and the main subjects of the study were mothers. Fourth, the research trends by research method were 73 quantitative studies (92.4%), 2 qualitative studies, 1 literature study, 2 mixed studies, and 1 other study. Fifth, the results of the analysis of influential factors were classified as risk factors and protection factors, which were specifically classified as individual factors, household factors, and social and environmental factors. Based on the study results, further discussion and practical suggestions were added.

Compressional and Shear Wave Properties of Cement Grout Including Carbon Fiber (탄소섬유를 포함한 시멘트 그라우트의 압축파 및 전단파 특성)

  • Choi, Hyojun;Cho, Wanjei;Yune, Chanyoung
    • Journal of the Korean GEO-environmental Society
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    • v.22 no.12
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    • pp.15-24
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    • 2021
  • In Korea, which is mostly mountainous, the proportion of tunnel and underground space development are increasing. Although the ground is reinforced by applying the ground improvement method during underground space development, accidents still occur frequently in Korea. In the grouting method, a representative ground reinforcement method, the effect was judged by comparing the total amount of injection material with the amount of injection material used during the actual grouting construction. However, it is difficult to determine whether the ground reinforcement is properly performed during construction or within the target ground. In order to solve this problem, it is necessary to study a new method for quality control during or after construction by measuring electrical resistivity after performing grouting by mixing carbon fiber, which is a conductive material, and microcement, which is a grout material. In this study, as a basic study, a cement specimen mix ed with 0%, 3%, 5%, 7% of carbon fiber was prepared to evaluate the performance of the grout material mixed with carbon fiber, which is a conductive material. The prepared specimens were wet curing for 3 days, 7 days, and 28 days under 99% humidity, and then compression wave velocity and shear wave velocity were measured. As a result of the compression wave velocity and shear wave velocity measurement, it showed a tendency to increase with the increase in the compounding ratio of carbon fibers and the number of days of age, and it was confirmed that the elastic modulus and shear modulus, which are the stiffness of the material, also increased.