• Journal of Nutrition and Health
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• 제36권5호
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• pp.459-469
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• 2003

We examined the effects of calcium intake levels on mineral metabolism during pregnancy using calcium-deficient young adult rats. Five week-old female Sprague-Dawley rats were fed normal Ca (NCa, 0.5%) and low Ca (LCa, 0.15%) diets for five weeks (pre-pregnancy). The low Ca intake group was then divided into three groups and fed low Ca (0.15%), normal Ca (0.5%) and high Ca (1.5%) diets for 3 weeks (pregnancy). All of the rats were mated with normal male rats. The control group was fed a consistently normal Ca (0.5%) diet during pre-pregnancy and pregnancy. On the day after delivery, dams and their pups were sacrificed. We measured total protein, albumin, alkaline phosphatase and mineral content in serum and weight, length, breaking force, ash and mineral content in the femur and lumbar (L2-L4) of the dams. Whole body mineral content was measured in the pups. There was no difference in weight gain and food intake among the groups. Serum total protein and albumin were in the normal range but a little lower during pregnancy. High Ca supplementation decreased serum Mg and Fe during pregnancy. Weight, ash and Ca of the femur and lumbar significantly decreased in rats fed a chronically low Ca diet during pre-pregnancy and pregnancy. Calcium supplementation levels were above normal during pregnancy and increased the bone weight and breaking force of rats fed the low Ca diet during pre-pregnancy. However, Ca supplementation did not increase the ash and Ca contents in the bones. High Ca supplementation during pregnancy significantly decreased Mg in the bones and increased Ca and P in the kidneys. Ash content of pups from dams fed the chronically low Ca diet decreased but there was no difference in whole body Ca among the groups. Mg and Fe in the whole body decreased in pups from dams fed the high Ca diet. Pregnancy performance was reduced in dams fed the low Ca diet. These results suggest that above normal Ca supplementation levels during pregnancy restored maternal bone status to some extent in rats fed the chronically low Ca diet. The same could not be said for mineral content. Also, high Ca supplementation during pregnancy may deteriorate mineral composition in bones and other tissues. Therefore, more detailed research is needed to facilitate sound recommendations on appropriate calcium intake during pregnancy. (Korean J Nutrition 36(5): 459∼469, 2003)

• 한국식품영양학회지
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• 제22권3호
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• pp.430-442
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• 2009

This study was designed to investigate the relationship between the dietary intake according to calorie intake from a coffee containing beverage and the bone health status of 189 female collegians. The study was conducted through questionnaires, anthropometric checkup, 3-days food records and ultrasound measurement of calcaneus bone mineral density. Subjects were divided into three groups: students not drinking coffee(non-coffee group, N=56), students consuming <100 kcal daily from coffee(low-calorie coffee group, N=84), and students consuming $\geq100$ kcal of their total daily calories from coffee(high- calorie coffee group, N=49). There were no significant differences in weight, height, body mass index, body fat and calcaneus bone mineral density among the three groups. The low-calorie coffee group usually drank black coffee or instant coffee mix, and the high-calorie coffee group habitually drank coffee with milk or sugar syrup. There were no significant differences in the mean daily energy and food intake among the three groups. However, vitamin $B_2$(p<0.05) and calcium (p<0.01) intake in the high-calorie coffee group were higher than in the non-coffee group. Also, mean intake of sugars, fish and shellfishes, milks and beverages in the high-calorie coffee group were also significantly higher than in non coffee group(p<0.05). There was no significant difference in the Korean Dietary Diversity Score(KDDS) among the three groups. The main calcium source was milk in all three groups, and milk intake(total and included with coffee) was highest in the high-calorie coffee group. Although no significant difference was apparent between the high-calorie and non-coffee groups concerning anthropometric factors and calcaneus bone mineral density, consumption of coffee may have influenced food and nutrient intake. The results suggest that consumption of milk-supplemented coffee may be of nutritional benefit.

• 대한지역사회영양학회지
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• 제8권6호
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• pp.927-937
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• 2003

This study was conducted to investigate dietary and other factors affecting bone mineral density (BMD) in Korean premenopausal women. Seventy-eight premenopausal women who visited the Health Promotion Center for health examinations volunteered to participate in this study. They were divided into two groups according to their bone status as shown by their T-scores: a non-osteoporotic group and a osteoporotic group. The results are as follows: The mean BMDs of the lumbar spine and femoral neck were 1.21$\pm$0.02$g/cm^2$ and 0.97$\pm$0.04$g/cm^2$, respectively. The BMD levels of the osteoporotic group were significantly lower than those of the non-osteoporotic group (p<0.001, respectively). The heights of the women in the osteoporotic group were significantly lower than those of the non-osteoporotic group (p<0.01) however, their body weights did not show any significant differences although they tended to be lower. The mean daily intake of energy was 1720$\pm$52㎉. When the nutrient intake was compared with the Korean recommended dietary allowances (RDA), calcium, Fe, vitamin A and riboflavin intakes were lower than the RDA. Their was no significant difference in the nutrient intake of the non-osteoporotic group and osteoporotic group except for the intakes of protein, fat and niacin. Their was no significant difference between the non-osteoporotic group and the osteoporotic group and all were within the normal range. However, the serum alkaline phosphatase level of the osteoporotic group was significantly higher than that of the non-osteoporotic group (p<0.001). Height measurements showed positive correlations with lumbar spine bone mineral density (LBMD, r=0.332, p<0.01) however there was no correlation with femoral neck bone mineral density (NBMD). Age, age at menarche, body weight, body mass index (BMI) and obesity showed no correlation with BMD. The BMD of the lumbar spine was significantly and positively related to the intake of niacin and vitamin C (r=0.236, p<0.05; r=0.274, p<0.05). Serum levels of calcium and phosphorus showed negative correlations with LBMD (r=-0.698, p=0.0001, r=-0.503, p=0.0001, respectively). The results suggested that the BMD of the lumbar spine was positively related to the intake of niacin and vitamin C in premenopausal women. Therefore, this study confirmed that one of the most effective ways to minimize bone loss would be have a higher intake of niacin and vitamin C rich foods and engaging habitually in physical activity may have a beneficial effect on BMD in the Premenopausal Period.

• Journal of Nutrition and Health
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• 제36권5호
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• pp.470-475
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• 2003

The purpose of this study was to investigate the effect of isoflavone supplementation using soymilk on bone mineral density in underweight college women aged 19-22 years with lower than average bone mass. The bone mineral density (BMD) of the lumbar spine and femoral neck of a number of underweight (BMI < 20) college women was measured. From this group, 33 subjects whose T-score value was below -1 were selected. Anthropometric measurements, dietary recall and BMD were measured before the study began and at the end of the 10th week. The 33 subjects were given 400 ml of soymilk containing 60 mg of isoflavones daily for 10 weeks. After 12 weeks at the end of 10 weeks treatment, the BMD of the subjects was reassessed. The average age of the subjects was 21.1 yrs. At the baseline, average height, weight, and BMI of the subjects were 161 cm, 49.1 kg, 18.8 kg/$m^2$, respectively. Mean daily intake of energy and protein was 1637.2 kcal and 61.2 g, respectively. Mean dietary isoflavone intake was 17.4 mg. Despite the 400 ml soymilk supplementation, there was no significant change in nutrient intake after the 10-week treatment. However, there were significant increases in lumbar spine and femoral neck BMD. After the study, the BMD of the subjects' spine and femoral neck was lower than that before the study. In conclusion, soymilk intake was associated with a significant increase in the BMD of the lumbar spine and femoral neck in underweight college women with lower than average bone mass. (Korean J Nutrition 36(5): 470~475, 2003)

• 한국식품영양과학회지
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• 제30권1호
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• pp.159-167
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• 2001

The objective of this study is to examine the factors affecting bone mineral density in pre- and postmenopausal women. The subject were 30 Korean premenopausal women with mean ages of 33.6 years, and 30 Korean post menopausal women with mean ages of 63.3 years without diagnosed diseases. Data for food and nutrient intake were obtained by the24-hour recall method. BMD of lumbar spine and femoral neck were measured by the dual-energy X-ray absorptiometry (DEXA). Anthropometric measurement were made, and a blood sample was taken for assay osteocalcin. The results are summarized as follows: 16.67% of the subjects in the premenopausal women and 87.33% of the subjects in the postmenopausal women was less than the korean RDA level exceping phosphorus and vitamin C. In the premenopausal women, BMD of lumbar spine is correlated significantly with anthropometric measurement such as weight, waist circumference, BMI, and body fat mass BMD of femoral neck for the premenopausal women is correlated significantly with weight, BMI, waist circumference, body fat mass, hip circumference, and BMDs of both site are negatively correlated with lean body mass, total body water, but they are not related with intake of nutrients in this study. In the postmenopausal women group, BMDs of both site are not significantly correlated with anthropometric measurement, but BMD of lumbar spine showed positive relation with intake of energy, protein, and carbohydrate. In conclusion, adequate nutrient intake, especially energy, protein have been suggested to prevent the loss of bone mineral density in the postmenopausal women. Also, adequate body weight and BMI have been suggested in the premenopausal women.

• Journal of Animal Science and Technology
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• 제63권5호
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• pp.998-1007
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• 2021

Brine mineral water (BMW) is groundwater near the deep sea, and the mineral component of the BMW is different from the water of the deep sea because the components of BMW are derived from the unique geographical features surrounding it. Recently, BMW has attracted attention due to the unique health-related minerals it possesses; however, the influence of BMW on physiological function has not yet been determined in domestic animals. Therefore, this experiment investigated the influence of BMW on the growth performance, water intake, blood properties, and immunoglobulin (Ig) levels of serum in growing-finishing pigs. A total of 64 pig barrows (Landrace × Yorkshire × Duroc) with an average initial weight of 40.56 ± 0.17 kg were used in the experiment, and 0%, 2%, 3%, and 5% samples of BMW diluted with freshwater were provided to experimental animals during the 56 days. We found that the gain/feed ratio in the 3% BMW group was significantly higher than that in the 5% BMW group of growing-finishing pigs (p < 0.05). The water intake was significantly increased in the 5% BMW group compared with the other groups (p < 0.05) of growing-finishing pigs. Additionally, the concentrations of red blood cells (RBCs), hemoglobin (HGB), and hematocrit (HCT) were significantly higher in the 3% BMW group than in the control group. The level of high-density lipoprotein cholesterol was higher in the 3% BMW group than in the 5% BMW group (p < 0.05). Furthermore, IgG and IgM levels in the serum were significantly higher in the 2% and 3% BMW groups than in the control group (p < 0.05). These results suggest that a dilution of 3% BMW in the intake water could improve the levels of RBCs and serum Igs in growing-finishing pigs.

• 대한지역사회영양학회지
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• 제24권1호
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• pp.18-23
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• 2019

Objectives: Although water is essential for life and can supply essential minerals, studies that evaluate calcium intake through drinking water are limited. The aim of this study was to assess calcium contents of natural mineral water (NMW) and its possible contribution to calcium intake in healthy adults. Methods: This study examined water consumption in 640 Korean adults with self-selected diet, analyzed the calcium content of 10 different brands of bottled NMWs sold in Korea, and assessed the amount of calcium intake from drinking water and its daily contribution to the recommended nutrient intake (RNI) of calcium. Results: Mean calcium content in 10 bottled NMWs was 20.9 mg/l. Daily water intakes from food composition database and calculated using energy intake based on 0.53 ml/kcal were 957.2 ml and 1109.8 ml for men and 848.3 ml and 951.6 ml for women, respectively, with a significant difference by gender (p<0.001). Daily drinking water intake was significantly higher among men than women (1203.9 ml vs. 1004.3 ml, respectively, p<0.001). Daily calcium intakes from foods were 564.0 mg for men and 534.2 mg for women. Daily possible calcium intakes from drinking bottled water were 25.2 mg for men and 21.0 mg for women (p<0.001). The contribution of daily calcium intake from drinking bottled water to RNI of calcium was 3.3% for men and 2.9% for women without significant difference. Conclusions: One half of the daily total water intake was consumed as drinking water, and possible calcium intake through drinking water was about 3% of RNI.

• Nutrition Research and Practice
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• 제16권6호
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• pp.775-788
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• 2022

BACKGROUND/OBJECTIVES: The prevalence of vitamin D deficiency in Koreans is quite high; however, until recently, Korean National Health and Nutrition Survey (KNHANES) had not analyzed the vitamin D intake among Koreans. Additionally, the Korean Dietary Reference Intake for vitamin D was established based on insufficient evidence. Therefore, we investigated vitamin D intake and its relationship with bone mineral density (BMD) in Korean adults using the combined data from the 2009-2011 KNHANES. MATERIALS AND METHODS: This study was conducted in 11,949 healthy adults. Vitamin D intake was assessed using a 24-h recall method, and the BMD was measured using dual-energy X-ray absorptiometry. RESULTS: The prevalence of vitamin D deficiency (< 20 ng/mL) was 64% in men and 77% in women. In women aged ≥ 50 yrs and men aged < 50 yrs, there was a significant positive correlation between vitamin D intake and serum 25-hydroxyvitamin D level after sun exposure adjustment. The BMD of postmenopausal women aged ≥ 50 yrs with a vitamin D intake of 5 ㎍/day or more was significantly higher than that of women with intake less than 5 ㎍/day. After adjusting for age, energy, and calcium intake, the vitamin D intake of the osteoporotic group was significantly lower than that of the osteopenia group in women. CONCLUSIONS: Since the relationship between vitamin D intake and BMD was observed in women aged ≥ 50 yrs, further research is needed to clarify these findings using cohort or randomized controlled trials.

• 한국수산과학회지
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• 제41권5호
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• pp.315-323
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• 2008

To measure the mineral content of fishes, we collected 177 individuals from 53 fish species from the east (Pohang), west (Gunsan), and south (Tongyeong) coasts of Korea. The mean content of the macro mineral in a 100 g sample taken from the edible portion of each fish was (in descending order): P(207.4 mg), K(169.7 mg), Na(101.6 mg), Ca(44.4 mg), and Mg(30.4 mg). In comparison, the mean content of micro mineral in the fishes was (in descending order): Zn ($8.98{\mu}g/g$), Fe ($5.03{\mu}g/g$), Cu ($0.76{\mu}g/g$), Mn ($0.43{\mu}g/g$), and Ni ($0.08{\mu}g/g$). We could not observe clear regional variation in the mineral content of fish species. With regard to minerals considered essential for humans, the amount of Ca per sample (100 g) was the highest in the Scyliorhinus torazame (465.4 mg), and than followed by Ammodytes personatus (338.0 mg), Dasyatis akajei (267.4 mg), Raja kenojei (248.1 mg), Conger myriaster (174.1 mg), Clupanodon punctatus (86.8 mg), Muraenesox cinereus (81.2 mg), and Engraulis japonica (70.4 mg). The daily average intake of the mineral through the fishes consisted of P (100.6 mg), K (82.3 mg), Na (49.3 mg), Mg (14.8 mg), Zn (0.44 mg), Fe (0.24 mg), Cu (0.04 mg) and Mn (0.02 mg). The respective intakes of macro mineral (P, Mg, Na, Ca, K) from the fishes were about 14.4, 4.2, 3.3, 3.1 and 1.8% of the dietary reference intakes for Koreans (KDRIs) set by the Korean Nutrition Society. In comparison, the respective intakes of micro mineral (Cu, Zn, Fe, Mn) from the fishes were about 4.6, 4.4, 2.4, and 0.6% of the KDRIs.

• 근관절건강학회지
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• 제19권3호
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• pp.350-361
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• 2012

Purpose: The purpose of this study is to explore the level of bone mineral densities of the femur neck and to identify factors affecting bone mineral density of the femur in Parkinson's disease (PD) patients. Methods: Participants were 121 PD patients visiting the outpatient clinic of D University Hospital in B City. Bone mineral density was measured at the femur neck by using a dual-energy x-ray absorptiometry. The serum vitamin D level, the amounts of milk intake, caffeine intake, cigaret smoking, and alcohol consumption, and the number of steps taken daily were measured. Past and present disease history, the medication history, and duration of the disease were also collected. The level of disability was obtained by neurologists using the Hoehn and Yahr stage and the Unified Parkinson's Disease Rating Scale. Results: Among PD patients, 57% had osteopenia and 15.7% had osteoporosis. The bone mineral density of the femur was associated with weight, serum vitamin D level, age, and working status. Conclusion: The identification of weight and serum vitamin D level as important predictive factors emphasizes the importance of balanced nutrition for PD patients.