• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.879-894
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• 2016

In micro-fluid systems, fluids are injected into extremely narrow polymer channels in small amounts such as micro-, nano-, or pico-liter scales. These channels themselves are embedded on tiny chips. Various specialized structures in the chips including pumps, valves, and channels allow the chips to accept different types of fluids to be entered the channel and along with flowing through the channels, exert their effects in the framework of different reactions. The chips are generally crystal, silicon, or elastomer in texture. These highly organized structures are equipped with discharging channels through which products as well as wastes of the reactions are secreted out. A particular advantage regarding the use of fluids in micro-scales over macro-scales lies in the fact that these fluids are much better processed in the chips when they applied as micro-scales. When the laboratory is miniaturized as a microchip and solutions are injected on a micro-scale, this combination makes a specialized construction referred to as "lab-on-chip". Taken together, micro-fluids are among the novel technologies which further than declining the costs; enhancing the test repeatability, sensitivity, accuracy, and speed; are emerged as widespread technology in laboratory diagnosis. They can be utilized for monitoring a wide spectrum of biological disorders including different types of cancers. When these microchips are used for cancer monitoring, circulatory tumor cells play a fundamental role.

• Journal of Veterinary Clinics
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• v.32 no.1
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• pp.85-90
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• 2015

In this study, we investigated the number of categories of veterinary medical devices registered by Animal and Plant Quarantine Agency (QIA) by 2013. We also analyzed the sales of the veterinary medical devices reported from Korea Animal Health Product Association (KAHPA) from 2011 to 2013. The registration rate of veterinary medical devices has sharply increased since 2008, and a total of 495 categories from 141 companies were registered by the end of 2013. The multi-frequency products registered for companion animals were ultrasound imaging system, x-ray system, microchip & reader, telemetry system transmitter, and hematology analyzer. The veterinary medical devices for farm animals include marker, artificial insemination catheter, injector, and ultrasound imaging system. Of these products, the multi-frequency products dominated on the veterinary medical devices market. The market size of 223 (45.0%) veterinary medical devices was estimated to be approximately 20.6 billion Won in 2013; the proportion of domestic products and imports was 56% to 44%; the proportion of domestic demand and export was 82% to 18%, respectively. This study suggested that the registration and sales of the veterinary medical devices have gradually increased as the demand of health care services got bigger in Korea.

• Korean Journal of Food Science and Technology
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• v.35 no.3
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• pp.470-474
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• 2003

DNA sequence information on small-subunit rRNA gene (16S rDNA) obtained from food-poisoning bacterial culture was used to investigate the presence of bacterial pathogens in food. By reverse dot blot detection method, presence of food-poisoning bacteria could be confirmed on hybridization of digoxigenin-labeled 16S rDNA Polymerase Chain Reaction (PCR) primer product and biotin-labeled specific oligonucleotide probe. Escherichia coli, Bacillus cereus. and Salmonella sp. were used as the representative food-poisoning bacterial microorganisms. An oligonucleotide probe, based on the variable region of 16S rRNA gene, was used as the specific probe. These tools may be more useful than classic biochemical method for rapid identification of contaminated food.

• 한국정보컨버전스학회:학술대회논문집
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• 2008.06a
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• pp.47-52
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• 2008

A radio-frequency identification(RFID) tag is a small, inexpensive microchip that emits an identifier in response to a query from a nearby reader. The price of these tags promises to drop to the range of $0.05 per unit in the next several years, offering a viable and powerful replacement for barcodes. The challenge in providing security for low-cost RFID tags is that they are computationally weak devices, unable to perform even basic symmetric-key cryptographic operations. Security researchers often therefore assume that good privacy protection in RFID tags is unattainable. In this paper, we explore a notion of minimalist cryptography suitable for RFID tags. We consider the type of security obtainable in RFID devices with a small amount of rewritable memory, but very limited computing capability. Our aim is to show that standard cryptography is not necessary as a starting point for improving security of very weak RFID devices. Our contribution is threefold: 1. We propose a new formal security model for authentication and privacy in RFID tags. This model takes into account the natural computational limitations and the likely attack scenarios for RFID tags in real-world settings. It represents a useful divergence from standard cryptographic security modeling, and thus a new view of practical formalization of minimal security requirements for low-cost RFID-tag security. 2. We describe protocol that provably achieves the properties of authentication and privacy in RFID tags in our proposed model, and in a good practical sense. Our proposed protocol involves no computationally intensive cryptographic operations, and relatively little storage. 3. Of particular practical interest, we describe some reduced-functionality variants of our protocol. We show, for instance, how static pseudonyms may considerably enhance security against eavesdropping in low-cost RFID tags. Our most basic static-pseudonym proposals require virtually no increase in existing RFID tag resources.

• Korean Journal of Optics and Photonics
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• v.22 no.2
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• pp.96-101
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• 2011

Operational and thermal characteristics of a thin disk Yb:YAG crystal with a thickness of 0.8 mm were studied using as a pumping source a fiber-coupled 930 nm laser diode. The heat generated in the crystal was dissipated by placing both surfaces in contact with copper plates with central hole, and the dependence of the temperature change in the illuminated spot on hole size was investigated by measuring the spectral change of the lasing peaks. The slope efficiency and optical-to-optical efficiency with respect to the LD pump power were as high as 42.2% and 34.8%, respectively. The temperature at the illuminated spot increased with diode current and with increasing hole size of the copper plate. When the hole size considerably exceeded the crystal thickness, the temperature rise deviated from the linear increase at high pump power.

• International journal of advanced smart convergence
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• v.7 no.3
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• pp.23-36
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• 2018

In wireless communication, efficient spectrum usage is an issue that has been an attractive research area for many technologies. Recently new technologies innovations allow compact radios to transmit with power efficient communication over very long distances. For example, Low-Power Wide Area Networks (LPWANs) are an attractive emerging platform to connect the Internet-of-Things (IoT). Especially, LoRa is one of LPWAN technologies and considered as an infrastructure solution for IoT. End-devices use LoRa protocol across a single wireless hop to communicate to gateway(s) connected to the internet which acts as a bridge and relays message between these LoRa end-devices to a central network server. The use of the (ISM) spectrum sharing for such long-range networking motivates us to implement spectrum sensing testbed for cognitive radio network based on LoRa and GNU radio. In cognitive radio (CR), secondary users (SUs) are able to sense and use this information to opportunistically access the licensed spectrum band in absence of the primary users (PUs). In general, PUs have not been very receptive of the idea of opportunistic spectrum sharing. That is, CR will harmfully interfere with operations of PUs. Subsequently, there is a need for experimenting with different techniques in a real system. In this paper, we implemented spectrum sensing for cognitive radio networks based on LoRa and GNU Radio, and further analyzed corresponding performances of the implemented systems. The implementation is done using Microchip LoRa evolution kits, USRPs, and GNU radio.

• Journal of Biomedical Engineering Research
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• v.25 no.6
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• pp.617-621
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• 2004

In recent, researchers in the field of Bioinformatics need to analyze thousands of genome sequences efficiently according to introduce of new analysis methods and technologies such as genome expression microchip. This rapid growth in the field of bio-engineering needs computing resources to analyze rapidly for genome sequences, but it does not introduce the computing resources due to an enormous investment expense. The core factor of this study is integrated environment based PC-Cluster system & high speed access rate up to 155Mbps, continuous collection system for bio-information at home and abroad. The results of the study are establishment & stabilization of information and communication infrastructure, establishment & stabilization of high performance computer network up to 155Mbps, development of PC-Cluster system with 32 nodes, a parallel BLAST on Cluster system, which can provides scalable speedup in terms of response time, and development of collection & search system for bio-information.

• Proceedings of the KIEE Conference
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• 2006.07c
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• pp.1645-1646
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• 2006

Micro ElectroMechanical Systems (MEMS) 기술을 이용한 초미세 유체 제어 시스템 (마이크로 펌프, 마이크로 밸브, 마이크로 채널, 마이크로 믹서 등)은 화학, 생명분야의 DNA 분석, 항원-항체 분석, 질병의 진단 등에 사용되는 lab-on-a-chip, micro total analysis system ($\mu$-TAS) 등에서 화학 및 바이오 유체를 제어하는 분석 시스템의 일부분으로서 사용되며 필수적으로 요구된다. 본 논문에서는 이러한 microchip을 구현하기 위해 초미세 유체 제어 소자인 마이크로 펌프와 밸브를 같은 기관 위에 polydimethylsiloxane (PDMS)와 indium tin oxide (ITO)-Glass를 사용하여 동일한 구조로 집적 하였다. 마이크로 펌프의 pumping rate은 인가 직류 펄스 전력의 주파수와 duty 비를 변화시켜 최적화하였다. 직류 펄스 전력 500 mW를 인가하였을 때 주파수 2 Hz, duty 비 7 %에서 약 $1.05{\mu}l/min$의 최대 유량이 측정되었다. 마이크로 밸브는 ITO 히터에 전력을 인가함으로서 유량의 on/off 제어가 잘 됨을 확인할 수 있었고 유체를 closing하기 위해 필요한 전력은 약 300 mW이다.

• Korean Chemical Engineering Research
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• v.57 no.2
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• pp.149-163
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• 2019

Under non-uniform electric field, a directional force along the electric field gradient is applied to matter having permanent or induced dipoles. The transport of particles by the directional force is called dielectrophoresis (DEP). Since the strength and direction of the DEP force depend on parameters, such as permittivity and conductivity of particles and surrounding media, and frequency of the applied AC electric field, particle can be precisely manipulated by controlling the parameters. Moreover, unlike electrophoresis, DEP can be applied to any particles where dipole is effectively induced by electric field. Such a DEP technique has been used in various fields, ranging from microfluidic engineering to biosensor and microchip research. This paper first describes the fundamentals of DEP, and discusses representative microelectrode designs used for DEP study. Then, exemplary applications of DEP, such as separation, capture and self-assembly of particles, are introduced.

• Journal of IKEEE
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• v.23 no.1
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• pp.295-301
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• 2019

A heater in a portable real-time polymerase chain reaction(PCR) system is one of the important factors for controlling the PCR thermocycle precisely. Since heaters are integrated on a small-sized PCR chip for rapid heating and fabricated by semiconductor processes, the cost of producing PCR chips is high. Here, we propose to use chip resistors as an inexpensive and accurate temperature control method. The temperature distribution was simulated using one or two chip resistors on a real-time PCR chip and the PCR chip with uniform temperature distribution was fabricated. The temperature rise and fall rates were $18^{\circ}C/s$ and $3^{\circ}C/s$, respectively.