• 대한한방부인과학회지
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• 제28권1호
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• pp.85-91
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• 2015

Objectives: Postmenopausal symptoms are subject to many factors. Recently, obesity has been suggested as a factor of hot flush. So this study aims to report the relationship between body composition and Menopause Rating Scale (MRS), The Menopause-specific Quality of Life Questionnaire (MENQOL) of postmenopausal women. Methods: We studied 42 climacteric women who had visited Kyung Hee University Hospital at Gangdong from April 2011 to July 2014. 42 women had filled out MRS, MENQOL, and they had taken body composition tests. Pearson correlation tests were conducted. (Correlation was statistically significant at the 0.05 level) Results: Correlation between psychological subscale of MENQOL and Waist-Hip Ratio (WHR) was statistically significant (pearson correlation coefficient=0.385; p-value=0.012). But other subscales of MRS and MENQOL were not statistically related with body composition. Conclusions: WHR could be an important factor of psychological health of menopausal women. So, abdominal fat reduction must be considered when curing menopausal symptoms. In connection with climacteric depression, well-designed studies would be necessary.

• 한국학교ㆍ지역보건교육학회지
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• 제24권3호
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• pp.13-22
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• 2023

Objectives: The purpose of this study was to provide baseline data for management policies by exploring the association between alcohol and mental health in menopause and andropause middle-aged Methods: This study used the data from from the 8th National Health and Nutrition Examination Survey (2019-2021). Adults between the ages of 40 and 64 were considered menopause and andropause middle-aged and 7,704 of the total number of 8,549 subjects were selected as the final study subjects without missing data. Mental health was defined as depression diagnosis and suicidal thoughts, and drinking was defined as current drinking and high-risk drinking. SAS 9.4 was used for all statistical analyses. Results: There were significant differences between menopause middle-aged men and women in current drinking (83.4% for men and 66.6% for women) and in high-risk drinking (24.2% for men and 4.9% for women). The significant factors affecting the depression diagnosis were identified as economic activity, income level, and subjective health status for men and economic activity, income level, subjective health status, and smoking for women (p < .05). The significant factors affecting suicidal ideation included economic activity, income level, and subjective health status for men and economic activity, high-risk drinking, current smoking, and subjective health status for women (p < .05). Conclusion: As a result of analyzing the association between alcohol and mental health in menopause and andropause middle-aged adults, Drinking alcohol and high-risk drinking in women were associated with mental health, but insignificantly in men. Based on this study, it is necessary to program development and health education for the physical and mental health of menopausal middle-aged women exposed to alcohol, and to develop menopausal mental health management policies that take into account the gender differences.

• 셀메드
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• 제13권14호
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• pp.17.1-17.23
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• 2023

Menopause is a physiological phase experienced by all women as part of normal aging known as menopause. Per se, menopause is not a disease, but hormonal imbalance may lead to menopausal symptoms in some women. The unani physician described that in Sinn-i-Inḥiṭāṭ/ Sinn al-Yās, Burūdat (coldness) increases lead to Ihtibās al-Tamth (amenorrhea) that can occur naturally. Besides, Khilt Dam (blood) production decreases from the liver, slight production occurs, tends towards Burūdat. Therefore, at this age, Ihtibās al-Tamth is associated with Alāmāt Sinn al-Yās(menopausalsymptoms) including weight gain, loss of appetite, hirsutism, fatigue, headache, backache, arthralgia, neck pain, general myalgia, nervousness, anxiety, depression, and insomnia. The traditional Unani manuscripts are enriched with knowledge for the management of Alāmāt Sinn al-Yās. Consequently, an extensive exploration of classical texts concerning the management of Alāmāt Sinn al-Yās was undertaken. Moreover, PubMed, Scopus, Google Scholar, and other indexing databases were thoroughly explored for evidence-based approaches to managing menopausalsymptoms. The principle management as per Unani texts is to treat the cause of Alāmāt Sinn al-Yās. Unani medicines with emmenagogue, anti-inflammatory, analgesic, cardioprotective, and neuroprotective properties are beneficial for the amelioration of Alāmāt Sinn al-Yās. Unani Herbs such as Asgandh, Aslusūs, Khārkhasak, Tagar, Shuneez, Ustukhuddus, Zafran, and Majūn Najāh possess properties and are proven scientifically for their efficacy in Alāmāt Sinn al-Yās. Hence, the substantiation and preservation of traditional knowledge assume paramount importance in facilitating prospective research and proving invaluable in the modern era. Moreover, the conduct of randomized controlled trials, systematic reviews, and meta-analyses becomes imperative.

• 정신신체의학
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• 제22권2호
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• pp.138-142
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• 2014

구강 작열감 증후군(Burning mouth syndrom)은 기질적인 질환 없이 구강이 타는 듯한 통증을 호소하는 질환이다. 병인으로는 신경병증, 폐경, 영양불균형 등 여러 요인이 관련되어 있을 것으로 추정되며, 정신의학적으로는 우울증이 가장 잘 동반된다. 진통소염제, 호르몬제, 항전간제 및 항우울제 등이 치료로 시도되었으나 효과는 비특이적이다. 이 증례보고는 폐경 후 여성에서 우울증에 동반된 구강 작열감 증후군에 대한 gabapentin의 효과를 보고한다. 항우울제는 우울증상을 호전시켰지만 구강증상에는 효과가 없었다. Gabapentin을 12주간 하루 300mg 용량으로 추가 투여 후 구강증상은 주관적으로 유의하게 감소되었다. 폐경 후 여성에서 항우울제로 개선되지 않는 구강 작열감 증후군 환자에서 gabapentin의 추가 투여가 효과적일 수 있다.

• 한국융합학회논문지
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• 제13권4호
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• pp.103-110
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• 2022

본 연구는 2016~2018년 국민건강영양조사의 자료를 활용하여 폐경기 여성의 우울 정도와 구강건강행태의 융합적 관련성을 파악하기 위해 실시되었다. 연구대상자는 40세부터 59세 여성 중 건강설문조사의 월경 여부 문항에서 '폐경'이라고 응답한 1,201명이었다. 자료 분석은 복합표본 교차분석 및 로지스틱 회귀분석을 실시하였다. 그 결과 PHQ-9 점수가 '10점 이상'인 집단이 '10점 미만' 집단에 비해 3.12배 흡연을 하는 경향이 나타나, 폐경 여성의 우울 정도는 구강건강행태 중 흡연과 깊은 관련성이 나타났다. 본 연구는 폐경 여성의 우울과 관련되어 있는 구강건강행태를 파악함에 따라 중년 여성의 건강 및 구강건강을 향상시키는 기초자료로 이용될 것을 기대한다.

• 대한간호학회지
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• 제29권2호
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• pp.225-237
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• 1999

The purpose of this study was to analyze the relationship among the health promoting behaviors, self-reported climacteric symptoms and depression on a cross-sectional survey desist The subjects were 108 middle-aged women who were nonhystrectomized and ranged in age from 40 to 60. They were selected in Seoul and Kyoung-ki province. Korea. Data were collected from Oct. 25 to Nov. 10, 1997 by a structured Questionnaire. The instrument used for this study was the revised Health Promotion Lifestyle Profile(HPLP) developed by Walker, Sechrist and Pender, revised Climacteric Symptoms Scale developed by Chi, Sung Ai, and the Beck's Depression Inventory(BID). The data were analyzed by the SPSS /PC$^{＋}$ program using t-test, ANOVA and Scheffe test as a post hoc and Pearson Correlation Coefficient. The results of the study were as follows ; 1. The mean score of health promoting behaviors was low(2.42$\pm$0.35). There were statistically significant difference in the score of health promoting behaviors according to the educational background. family income, marital satisfaction, and whether or not taking a restoraitve food(t ＝－2.07, F＝2.60~7.57, p＜0.05). 2. The mean score of self-reported climacteric symptoms was 1.69 ; 99% of middle-aged women had symptoms. There were statistically significant difference in the score of middle-aged women's self-reported climacteric symptoms according to the age, number of children, educational background, occupation, family income, marital satisfaction, whether or not receiving hormone replacement therapy(HRT) or consultation experience with a professional, and perceived health status(t＝－2.04~3.69. F＝2.87~11.63, p＜0.05). 3. The mean score of depression was 10.84. There were statistically significant differences in the score of the depression according to the age, number of children, educational background, occupation, marital satisfaction, whether or not receiving menopausal treatment or consultation by a professional, and perceived health status(t ＝－2.25~3.00, F＝3.50~9.24, p＜0.05). 4. Women's degree of health promoting behaviors was a negative correlation with the degree of climacteric symptoms(r＝－0.19, p＝0.03) and the degree of depression(r＝－0.23, p＝0.01). The degree of climacteric stmptoms was a positive correlation with the degree of depression(r＝0.64 p＝0.01). In conclusion. health promoting behavior should be considered when developing nursing strategies for middle-aged women. especially when dealing with climacteric symptoms and depression.

• 대한간호학회지
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• 제50권3호
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• pp.487-500
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• 2020

Purpose: This study aimed to evaluate the validity and reliability of the Korean version of Menopause-Specific Quality of Life (MENQOL). Methods: The MENQOL was translated into Korean according to algorithm of linguistic validation process. A total of 308 menopausal women were recruited and assessed using the Korean version of MENQOL (MENQOL-K), the World Health Organization Quality of Life Brief Version (WHOQOL-BREF), and Center for Epidemiological Studies Depression Scale (CES-D-K). In estimating reliability, internal consistency reliability coefficients were calculated. Validity was evaluated through criterion validity and construct validity with confirmatory factor analyses using SPSS 23.0 and AMOS 25.0 software. Results: In item analyses, the "increased facial hair" symptom was excluded because of the low contribution of MENQOL-K. The confirmatory factor analysis supported good fit and reliable scores for MENQOL-K model, and the four-factor structure was validated (χ²=553.28, p<.001, NC=1.84, RMSEA=.05, AGIF=.85, AIC=765.28). The MENQOL-K consists of 28 items in 4 domains, including vasomotor (3 items), psychosocial (7 items), physical (15 items), and sexual subscales (3 items). There was an acceptable criterion validity with moderately significant correlation between MENQOL-K and WHOQOL-BREF. The Cronbach's α for the 4 subsacles ranged from .80 to .93. Conclusion: The MENQOL-K is a valid and reliable scale to measure condition-specific quality of life for perimenopausal and postmenopausal women. It can be used to assess the impact of menopausal symptoms on the quality of life of Korean women in clinical trials.

• 동의신경정신과학회지
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• 제31권2호
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• pp.77-88
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• 2020

Objectives: The study evaluated middle-aged women using the Core Seven Emotions Inventory-short form (CSEI-s) followed by a correlation analysis with Menopause Rating Scale (MRS). Methods: In this study, the medical records of 47 women who visited W University Oriental Medicine Hospital and completed the CSEI-s and MRS were evaluated. A total of 47 women were analyzed using SPSS (Statistical Package for the Social Science, IBM, United States of America, Version 23.0). Frequency analysis, descriptive analysis, independent t-test, one-way ANOVA, Scheffe test, and correlation analysis were conducted. Results: 1. Approximately one-third of all subjects were more than cautious expressing joy and fright. 2. According to their educational status, high-school graduates thought they were superior to those with a bachelor's degree or above. 3. Anger was expressed with caution in the group with severe menopausal symptoms. 4. Anger, thought, depression, sorrow, fear, and fright showed a positive correlation with MRS scores. 5. Among premenopausal and postmenopausal women, fright was associated with menopausal symptoms and response by the autonomous nervous system. Conclusions: The results suggest that CSEI-s can be used to measure the psychological symptoms of middle-aged women.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 2003년도 정기총회 및 학술발표회
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• pp.51-51
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• 2003

The medicinal plant Cimicifuga Racemosa (Black cohosh) has been used to treat many kinds of neuronal and menopausal symptoms, such as arthritis, menopausal depression, nerve pain, etc. Here, we examined the effect of Cimicifugoside (CF), one of triterpene glycosides which have been known as pharmacologically active ingredients of C. Racemosa, on nicotinic acetylcholine receptor (nAChR)-mediated catecholamine (CA) secretion in bovine adrenal chromaffin cell. Cimicifugoside inhibited calcium increase induced by 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP), a nAChR agonist with a half maximal inhibitory concentration (IC50) of 18${\pm}$2${\mu}$M. In contrast, cimicifugoside did not affect the calcium increases evoked by high K$\^$+/, veratridine, and bradykinin. The DMPP-induced sodium increase was also inhibited by cimicifugoside with IC50 of 2${\pm}$0.3${\mu}$M, suggesting that the activity of nAChRs is inhibited by cimicifugoside. Cimicifugoside did not effect on the KCl-induced secretion but markedly inhibited the DMPP-induced catecholamine secretion which was monitored by carbon-fiber amperometry in real time, and by high performance liquid chromatography (HPLC) through electrochemical detection. The results suggest that cimicifugoside selectively inhibits nAChR-mediated response in bovine chromaffin cells.

• 융합정보논문지
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• 제10권5호
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• pp.224-231
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• 2020

본 연구의 목적은 피톤치드흡입이 폐경기 여성의 기분상태 및 건강 관련 삶의 질에 변화를 8주간 실험을 통하여 분석하는 것이였다. 연구대상자는 서울 소재 D, N구의 폐경 후 2년 이하 41명을 목적적 표집하였다. 실험설계는 피톤치드흡입집단과 통제집단으로 구성되는 연구대상자 요인과 사전측정(0week)·중간측정(4week)·사후측정(8week)의 3개 측정시점으로 구성되는 2×3 반복측정에 의한 요인설계를 이용하였다. 본 연구의 종속변인으로는 기분상태와 건강관련 삶의 질로 설정하였으며 사전측정·중간측정·사후측정 3회 질문지를 통하여 자료를 수집하였다. 분석방법은 one-way ANOVA와 사후검증을 실시하였다. 도출된 결과는 첫째, 폐경기 여성의 피톤치드흡입집단이 통제집단에 비하여 긴장, 우울, 피로, 혼돈 요인의 감소 효과와 활력 요인의 증가 효과가 통계적 유의하게 나타났다. 둘째, 폐경기 여성의 피톤치드흡입집단은 통제집단에 비하여 유능감, 정신적 안녕, 안정성, 활력 요인에서 통계적 유의한 증가 추이를 나타내었다.