• 한국심리학회지:학교
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• 제17권2호
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• pp.199-222
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• 2020

이 연구는 사회부과적 완벽주의가 불확실성에 대한 인내력 부족과 반추적, 반성적 반응양식을 매개로 우울에 미치는 영향을 검증하여 대학생에게 나타나는 우울을 효과적으로 해결할 수 있는 방안을 모색하고자 실시하였다. 이를 위해 중부권 소재의 대학에 재학중인 대학생 283명을 대상으로 우울(CES-D), 다차원적 완벽주의 척도(HMPS), 불확실성에 대한 인내력 부족 척도(IUS), 우울 기분에 대한 반응양식 척도(RDQ)를 사용하여 설문을 실시하였다. 연구 결과는 다음과 같다. 첫째, 사회부과적 완벽주의 불확실성에 대한 인내력 부족, 반추적 반응양식은 정적인 상관이 나타났지만 반성적 반응양식과는 상관이 나타나지 않았다. 둘째, 사회부과적 완벽주의가 우울에 영향을 미치는 과정에서 불확실성에 대한 인내력 부족을 1차 매개변인으로 설정하고 반추적 반응양식을 2차 매개 변인으로 설정하여 관계를 검증하였고, 모든 매개효과는 의미있는 수준이었다. 한편 2차 매개변인을 반성적 반응양식으로 설정하여 매개효과를 검증한 결과 매개효과는 유의하지 않았다. 이러한 결과로 볼 때 사회부과적 완벽주의로 나타나는 우울을 예방하기 위해서는 불확실성에 대한 인내력 부족과 반추적 반응양식에 초점을 두어 개입한다면 유용할 수 있을 것이다. 마지막으로 결과를 바탕으로 연구의 의의 및 한계점을 논의하였다.

• 대한가정학회지
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• 제40권10호
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• pp.65-76
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• 2002

The purpose of this study win to examine the relation between level of income, perceived parental behaviors, and ego-identity of school-aged children. The subjects were 356 children in the 6th grade selected from six elementary schools in Seoul and Keunggi-Do. The subjects were asked to complete the questionnaire on ego-identity and perceived parental behaviors. The data was analyzed by Mean, SD, Cronbach's α, Pearson's correlation and Multiple Regression. The major findings were as follows : 1. The level of income(antecedent variable) was significantly related with perceived parental behavior(mediator) and ego-identity of school-aged children(dependent variable). 2. The effects of level of income on ego-identity of school-aged children became lower after control of the effects of perceived parental behaviors. In other words, perceived parental behaviors partially mediated the effects of level of income on ego-identity of school-aged children.

• The Journal of Asian Finance, Economics and Business
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• 제7권6호
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• pp.449-456
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• 2020

This study examines the relation between the quality of leader-member relationship and operational performance of processing enterprises employees in Vietnam, while job satisfaction and innovation are as a mediator variable. In depth interviews are first conducted with five managers and professional workers in five processing enterprises to determine the latent variables and build the structured questionnaire with observed variables. A quantitative survey with 438 employees and managers from 300 processing enterprises was carried out. The method of exploratory factor analysis (EFA), Cronbach's alpha analysis, and confirmatory factor analysis (CFA) was used to test the reliability, the convergent nature, and the consistency of the concepts. Structural equation modeling (SEM) is used to test the proposed model. The result shows that job satisfaction, innovation and operational performance have positive effects on the quality of leader-member relationship. The relationship between leaders and members had indirect impact on employee's operational performance via their job satisfaction and innovation, which illustrates a mediator role of job satisfaction and innovation for employees' performance. The findings of this study suggest that managers need to focus on developing relationship with employees to improve their satisfaction, innovation and performance.

• 한국조리학회지
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• 제22권6호
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• pp.33-51
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• 2016

The hotel industry needs to make the competitive advantage difficult to be imitated in order to remain sustainable in competitive business circumstances. Front-line employees' service-oriented citizenship behaviors(OCBs) can be such a strength from the perspective of organizational system. With an aim of investigating the antecedents of the hotel front-line employees' service-oriented OCBs, this study proposed a theoretical framework linking authentic leadership to service-oriented OCBs with goal commitment as a mediator. A total of 260 cases without missing values have been used for the final analysis and structural equation modeling (SEM) is employed using the SPSS and AMOS 7. It was first found that self-awareness and relational transparency of authentic leadership made a significant impact on their goal commitment while balanced processing and moral perspective failed to influence them. Second. goal commitment influenced all sub-factors of service-oriented OCBs. Third, moral perspective and relational transparency of authentic leadership significantly influenced service-oriented OCBs while self-awareness and relational transparency failed to make it. Finally, goal commitment significantly makes an intervening effect for the relationship between self-awareness & service-oriented OCBs and relational transparency & service-oriented OCBs but failed to intervene the other relationships. The results provide theoretical and practical implications regarding directions of leadership styles and HR management in the hotel industry and suggestions for the further extended studies.

• Biomolecules & Therapeutics
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• 제7권4호
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• pp.315-321
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• 1999

Since it has been known that hypoxia increases inducible nitric oxide synthase (iNOS) gene expression through hypoxia responsive element, it was possible to establish the hypothesis that nitric oxide could be a mediator of hypoxia to inhibit Cyplal promoter activity. In order to test this hypothesis, we have undertaken the study to examine the effects of hypoxia and nitric oxide on Cyplal promoter activity in Hepa I cells. Mouse Cyplal 5'flanking DNA, 1.6 Kb was cloned into pGL3 expression vector in order to construct pmCyplal-Luc. Hepa I cells were transfected with pmCyplal-Luc and were treated with $10^{-9}$ M TCDD and nitric oxide producing agents, such as lipopolysaccharide(LPS), sodium nitroprusside (SNP). Luciferase activity of reporter gene was measured from pmCyplal-Luc transfected Hepa I cell lysate which contains 2 g total protein using luciferin as a substrate. Nitric oxide producing agents, such as lipopolysaccharide (LPS), sodium nitroprusside(SNP) showed inhibition of luciferase activity that was induced by $10^{-9}$M TCDD treatment with dose dependent manner. Concomitant treatment of 1mM $N^G$-nitro-ι-arginine with $10^{-6}$~$10^{-4}$M sodium nitro-prusside recovered luciferase activity from the TCDD induced luciferase activity that was inhibited by nitric oxide producing agents. These demonstrated that nitric oxide could be a mediator of inhibitors on dioxin induced Cyplal expression in Hepa I cells.

• Archives of Pharmacal Research
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• 제25권3호
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• pp.343-348
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• 2002

Carbon monoxide (CO) are produced by heme oxygenase (HO), and HO was detected in hypothalamus. However, the roles of CO produced in hypothalamus was not fully elucidated. So, we tested the effects of CO on body temperature because preoptic-anterior hypothalamus was known as the presumptive primary fever-producing site. CO-saturated aCSF ($4{\;}{\mu}l$, i.c.v.) and hemin ($10{\;}{\mu}g$, i.c.v.) elicited marked febrile response. Pretreatment with indomethacin completely inhibited CO- and hemin-induced fever. Zinc protoporphyrin-IX ($10{\;}{\mu}g$, i.c.v.) or ODQ ($50{\;}{\mu}g$, i.c.v.) partially reduced hemin-induced febrile response. Dibutyryl-cGMP ($100{\;}{\mu}g$, i.c.v.) produced profound febrile response and this febrile response was attenuated by indomethacin. These results indicate that endogenous CO may have a role as a pyrogenic mediator in CNS and CO-mediated pyresis is dependent on prostaglandin production and partially on activation of soluble guanylate cyclase.

• 한국지역사회생활과학회지
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• 제21권3호
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• pp.341-350
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• 2010

The purpose of this study was to identify the level of care givers' job stress, burn-out and stress coping strategies and to determine the mediator effect of coping strategies in the relationship between job stress and burnout. The research subjects were 193 care givers for the elderly in Jeollanamdo. The data analysis was performed by using SPSS Win 17.0. The results of this study were as follows; The level of care givers' job stress which they perceived was 2.68 points in a scale of 5 points, stress coping strategies was 2.39 points in a scale of 4 points, and the degree of burnout was 2.27 points in a scale of 5 points. There was a positive correlation between the care givers' job stress and burnout. There was a negative correlation between the job stress and stress coping strategies. There was a positive correlation between the stress coping strategies and burnout. And the stress coping strategies showed mediating effects between the care givers' job stress and burnout. Accordingly, we found that stress coping strategies had an mediating effect on care givers' burnout and various coping strategies were related to the burnout.

• Natural Product Sciences
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• 제23권1호
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• pp.1-4
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• 2017

Sinensetin, a pentamethoxyflavone, is known to exert various pharmacological activities including anti-angiogenesis, anti-diabetic and anti-inflammatory activities. However, its effects on the human mast cell - 1 (HMC-1) mediated inflammatory mechanism remain unknown. To explore the mediator and cellular inflammatory response of sinensetin, we examined its influence on phorbol 12-myristate 13-acetate (PMA) plus A23187 induced inflammatory mediator production in a human mast cell line. In this study, interleukin (IL)-6 production was measured using the enzyme-linked immunosorbent assay and reverse transcription polymerase chain reaction. Sinensetin inhibited PMA plus A23187 induced IL-6 production in a dose-dependent manner as well as IL-4, IL-5 and IL-8 mRNA expression. Furthermore, sinensetin inhibited signal transducer and activator of transcription 3 (STAT3) phosphorylation, suggesting that sinensetin inhibits the production of inflammatory mediators by blocking STAT3 phosphorylation. Moreover, sinensetin was found to inhibit nuclear factor kappa B activation. These findings suggest that sinensetin may be involved in the regulation of mast cell-mediated inflammatory responses.

• 영어어문교육
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• 제15권4호
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• pp.345-364
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• 2009

This study attempts to provide a comprehensive framework for listening strategy use among university students in Korea in relation to TOEIC listening scores. In particular, this study tests whether motivation, based on the self-determination theory, mediates listening strategy use on listening comprehension (LC) process and whether reading comprehension ability moderates the use of listening strategy in LC achievement. One hundred seventy six freshmen students participated in the study during their first semester required English course. Self-report questionnaires were used to assess students' motivation and LC strategy use. The responses were statistically analyzed via the moderator and mediator model. The results indicate that internalized motivation mediates the use of listening strategy in LC achievement; however, reading comprehension skill doesn't affect students' use of listening strategies in relation to listening skill achievement. In other words, students who have internalized motivation were able to utilize listening strategies effectively in terms of achievement of the TOEIC listening skills. The findings of the current study offer in-depth understanding of the relationship among use of LC strategies, intrinsic motivation, and listening skill achievement shared by the mediator and moderator models.

• 가정간호학회지
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• 제24권2호
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• pp.160-168
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• 2017

Purpose: Optimism is an important psychological variable that functions positively in stress adaptation process. The purpose of this study was to identify either a mediating or moderating effect of optimism in the relationship between stress and well-being among mothers of children with diabetes mellitus. Methods: A sample of 109 mothers of children with diabetes mellitus was recruited in a tertiary hospital in B city and they completed self-reported questionnaires. Multiple regression analysis models were used to test the mediating and moderating effects of optimism in the relationship between stress and well-being. Results: The results of the multiple and hierarchical regression analysis showed that the role of optimism was examined a partial mediator of the relation between stress and well-being, not a moderator. Increased stress was associated with decreasing optimism and well-being, and increased optimism predicted increased well-being among mothers of children with diabetes mellitus. Conclusion: Optimism is more likely to play a role as mediator, rather than as a moderator. This finding suggests the importance of optimism in improving the well-being of mothers of children with diabetes mellitus.