• Journal of Animal Science and Technology
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• v.62 no.6
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• pp.884-892
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• 2020

Corticosterone is known as a biological stress index in many species including birds. Feather corticosterone concentration (FCC) has increasingly been used as a measure for chronic stress status in broiler chickens. As sample preparation is the first step of analytical process, different techniques of feather matrix disruption need to be validated for obtaining better result in analysing corticosterone extraction. The current study was a validation of pulverizing the feather by bead beater (BB) and surgical scissors (SS) processing prior to corticosterone extraction in feather of broiler chickens. The type of feather processing prior to the hormone extraction may alter the final output. Thereby, finding a standard method according to laboratory facilities is pivotal. This study carried out to determine the effects of feather pulverization methods on the extraction amount of corticosterone in broiler chickens. Feathers were sampled from four weeks old Ross 308 broiler chickens (n = 12 birds). All broiler chickens were kept under the same environmental condition and had access to feed and water. Feather samples were assigned to one of the following processing methods 1) using a BB for pulverizing and 2) using a SS for chopping into tiny pieces. Each sample was duplicated into two wells during enzyme immunoassay (EIA) analysis to improve the accuracy of the obtained data. The results showed lower standard errors and constant output of FCC by using the BB method compared with the SS method. Overall comparison of FCC showed a significantly higher (p < 0.001) amount of the FCC in the BB compared with the SS. Overall, using the BB method is recommended over the SS method for feather processing due to the ability to homogenize a large number of samples simultaneously, ease of use and greater extraction of feather corticosterone.

• Journal of radiological science and technology
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• v.45 no.2
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• pp.111-116
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• 2022

In this study, the applicability of machine learning for the development of a simulator for general X-ray examination education is evaluated. To this end, k-nearest neighbor(kNN), support vector machine(SVM) and neural network(NN) classification models are analyzed to present the most suitable model by analyzing the results. Image data was obtained by taking 100 photos each corresponding to Posterior anterior(PA), Posterior anterior oblique(Obl), Lateral(Lat), Fan lateral(Fan lat). 70% of the acquired 400 image data were used as training sets for learning machine learning models and 30% were used as test sets for evaluation. and prediction model was constructed for right-handed PA, Obl, Lat, Fan lat image classification. Based on the data set, after constructing the classification model using the kNN, SVM, and NN models, each model was compared through an error matrix. As a result of the evaluation, the accuracy of kNN was 0.967 area under curve(AUC) was 0.993, and the accuracy of SVM was 0.992 AUC was 1.000. The accuracy of NN was 0.992 and AUC was 0.999, which was slightly lower in kNN, but all three models recorded high accuracy and AUC. In this study, right-handed PA, Obl, Lat, Fan lat images were classified and predicted using the machine learning classification models, kNN, SVM, and NN models. The prediction showed that SVM and NN were the same at 0.992, and AUC was similar at 1.000 and 0.999, indicating that both models showed high predictive power and were applicable to educational simulators.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.5
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• pp.309-316
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• 2022

This paper presents nonlinear numerical analysis results which were compared with the tested tensile strengths of CFRP(Carbon Fiber Reinforced Plastic) laminates with 14 different stacking sequences. The composite laminate coupons were cured under an autoclave pressure using resin-impregnated unidirectional tapes. The nonlinearity of the matrix was considered for the analysis, which was obtained from lamina tests. The Hashin failure criteria and progressive failure analysis were used for the nonlinear finite element analysis. The comparison results show that the current approach is acceptable to predict the tensile strengths of the CFRP laminate coupons with various stacking sequences and no damage. However, it is not acceptable to predict the tensile strengths of the laminate specimens with a center hole.

• Advances in aircraft and spacecraft science
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• v.8 no.4
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• pp.345-372
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• 2021

The analysis of nonlinear vibrations, buckling, post-buckling, flutter boundary determination and post-flutter behavior of a homogeneous curved plate assuming cylindrical bending is conducted in this article. Other assumptions include simply-supported boundary conditions, supersonic aerodynamic flow at the top of the plate, constant pressure conditions below the plate, non-viscous flow model (using first- and third-order piston theory), nonlinear structural model with large deformations, and application of mechanical and thermal loads on the curved plate. The analysis is performed with constant environmental indicators (flow density, heat, Reynolds number and Mach number). The material properties (i.e., coefficient of thermal expansion and modulus of elasticity) are temperature-dependent. The equations are derived using the principle of virtual displacement. Furthermore, based on the definitions of virtual work, the potential and kinetic energy of the final relations in the integral form, and the governing nonlinear differential equations are obtained after fractional integration. This problem is solved using two approaches. The frequency analysis and flutter are studied in the first approach by transferring the handle of ordinary differential equations to the state space, calculating the system Jacobin matrix and analyzing the eigenvalue to determine the instability conditions. The second approach discusses the nonlinear frequency analysis and nonlinear flutter using the semi-analytical solution of governing differential equations based on the weighted residual method. The partial differential equations are converted to ordinary differential equations, after which they are solved based on the Runge-Kutta fourth- and fifth-order methods. The comparison between the results of frequency and flutter analysis of curved plate is linearly and nonlinearly performed for the first time. The results show that the plate curvature has a profound impact on the instability boundary of the plate under supersonic aerodynamic loading. The flutter boundary decreases with growing thermal load and increases with growing curvature.

• Journal of the Korean Society of Food Culture
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• v.37 no.6
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• pp.540-546
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• 2022

This study aimed to determine the changes in the vitamin B₅ content of raw and cooked vegetables. The nineteen vegetables were subjected to different cooking methods, viz. blanching, boiling, pan-broiling, and steaming. Vitamin B₅ was quantified by reversed-phase high-performance liquid chromatography (HPLC) using photodiode-array (PDA) detection (200 nm). The standard reference materials (SRM) were used to validate the accuracy of vitamin B₅ measurement method used in this study. The cooking yields ranged from 82.63 to 107.62% and decreased in most of the vegetables except bitter melon, curled mallow, and eggplant. The raw kabocha squash, Danhobak, had the highest vitamin B₅ content (0.671 mg/100 g) among the samples. All cooked vegetables showed lower vitamin B₅ content compared to the raw samples. The true retention ranged from 0% (crown daisy, blanching) to 84.49% (kabocha squash, steaming). These results indicate that vitamin B₅ is degraded after cooking. Pan-broiling and steaming are better cooking methods than the others for retaining vitamin B₅. The true retention of vitamin B₅ in the samples markedly depends on the cooking method and food matrix. These results can be used as important basic data for nutritional evaluation of meals.

• Journal of Cadastre & Land InformatiX
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• v.51 no.2
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• pp.141-150
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• 2021

Fine dust is a substance that greatly affects human health, and various studies have been conducted in this regard. Due to the human influence of particulate matter, various studies are being conducted to predict particulate matter grade using past data measured in the monitoring network of Seoul city. In this paper, predictive model have focused on particulate matter concentration in May, 2019, Seoul. The air pollutant variables were used to training such as SO₂, CO, NO₂, O₃. The predictive model based on Adaboost, and training model was dividing PM₁₀ and PM_2.5. As a result of the prediction performance comparison through confusion matrix, the Adaboost model was more conformable for predicting the particulate matter concentration grade. Although air pollutant variables have a higher correlation with PM2.5, training model need to train a lot of data and to use additional variables such as traffic volume to predict more effective PM₁₀ and PM_2.5 distribution grade.

• Journal of Electrochemical Science and Technology
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• v.13 no.2
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• pp.292-307
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• 2022

The study presents kinetics of degradation and mineralization of an anti-epileptic drug Lamotrigine (LAM) in the aqueous matrix by electrochemical advanced oxidation process (EAOP) on Ti/DSA (Ta₂O₅-Ir₂O₅) and Stainless Steel (SS) anodes using sodium sulphate as supporting electrolyte. On both the anodes, kinetic behaviour was pseudo-first-order for degradation as well as mineralization of LAM. On Ti/DSA anode, maximum LAM degradation of 75.42% was observed at an associated specific charge of 3.1 (Ah/litre) at a current density of 1.38 mA/cm² and 100 ppm Na₂SO₄ concentration. Maximum mineralization attained was 44.83% at an associated specific charge of 3.1 (Ah/litre) at a current density of 1.38 mA/cm² and 50 ppm concentration of Na₂SO₄ with energy consumption of 2942.71 kWh/kgTOC. Under identical conditions on SS anode, a maximum of 98.92% LAM degradation was marked after a specific charge (Q) of 3.1 (Ah/litre) at a current density of 1.38 mA/cm² and 100 ppm concentration of Na₂SO₄. Maximum LAM mineralization on SS anode was 98.53%, marked at a specific charge of 3.1 (Ah/litre) at a current density of 1.38 mA/cm² and 75 ppm concentration of Na₂SO₄, with energy consumption of 1312.17 kWh/kgTOC. Higher Mineralization Current Efficiency (MCE) values were attained for EAOP on SS anode for both degradation and mineralization due to occurrence of combined electro-oxidation and electro-coagulation process in comparison to EAOP on Ti/DSA anode due to occurrence of lone electro-oxidation process.

• Archives of Plastic Surgery
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• v.49 no.6
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• pp.710-715
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• 2022

Background The latissimus musculocutaneous flap (LD flap) is a useful option for breast reconstruction following mastectomy. It has the advantage of obtaining sufficient tissue padding and natural shape by using autologous tissue. However, with the emergence of the skin-sparing mastectomy technique and artificial dermis matrix, direct-to-implant (DTI) breast reconstruction has become the first choice of surgery. The purpose of this study was to compare the satisfaction levels of patients who underwent DTI and LD flap with implant using patient-reported Breast-Q results. Methods A retrospective study was performed reviewing the records of 49 women who underwent immediate breast reconstruction with DTI or LD flap with implant and responded to the BREAST-Q questionnaire after the operation. The patient-reported breast-Q results were analyzed and correlated to the demographic information and intraoperative information. Results A total of 26 patients who underwent reconstruction with LD flap with implant and 23 patients with DTI were identified and responded to the questionnaire after an average of 32.3 and 10.4 months postoperation, respectively. According to the patient response to the breast-q values, satisfaction with breast was 60.0 and 57.0 points, psychosocial well-being 61.0 and 60.0 points, and sexual well-being 41.0 and 43.0 points in the two groups. Overall, there was no significant difference in the breastQ score between the two groups. Conclusion Patients who underwent DTI breast reconstruction seemed equally satisfied with the appearance and outcome of their breast reconstruction compared with LD flap with implant. Therefore, it appears that DTI is adequately replacing LD with implant.

• Archives of Plastic Surgery
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• v.50 no.1
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• pp.3-9
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• 2023

Background In breast reconstruction, synthetic meshes are frequently used to replace acellular dermal matrix (ADM), since ADM is expensive and often leads to complications. However, there is limited evidence that compares the types of substitutes. This study aimed to compare complications between materials via a network meta-analysis. Methods We systematically reviewed studies reporting any type of complication from 2010 to 2021. The primary outcomes were the proportion of infection, seroma, major complications, or contracture. We classified the intervention into four categories: ADM, absorbable mesh, nonabsorbable mesh, and nothing used. We then performed a network meta-analysis between these categories and estimated the odds ratio with random-effect models. Results Of 603 searched studies through the PubMed, MEDLINE, and Embase databases, following their review by two independent reviewers, 61 studies were included for full-text reading, of which 17 studies were finally included. There was a low risk of bias in the included studies, but only an indirect comparison between absorbable and non-absorbable mesh was possible. Infection was more frequent in ADM but not in the two synthetic mesh groups, namely the absorbable or nonabsorbable types, compared with the nonmesh group. The proportion of seroma in the synthetic mesh group was lower (odds ratio was 0.2 for the absorbable and 0.1 for the nonabsorbable mesh group) than in the ADM group. Proportions of major complications and contractures did not significantly differ between groups. Conclusion Compared with ADM, synthetic meshes have low infection and seroma rates. However, more studies concerning aesthetic outcomes and direct comparisons are needed.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.3
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• pp.59-67
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• 2023

Purpose : Epithelial-to-mesenchymal transition (EMT) is recognized as an important cellular response in metastatic proceduresand characterized by loss of cellular polarity as well as gain of mesenchymal features, which enables migration and invasion. Hepatocellular carcinoma (HCC) is one of the most common primary carcinomas in the liver and exhibits a poor prognosis due to frequent extrahepatic metastasis. Taraxacum officinale has been used for a long time in oriental medicine because of its various pharmacological activitiessuch as anti-rheumatic, anti-inflammatory, antioxidative, and anticarcinogenic activities. In this study, the anti-metastatic activity of T. officinale water extract (TOWE) and ethanol extract (TOEE) was investigated through the regulation of EMT in the Huh7 cells. Methods : The effects of TOWE and TOEE on migratory and invasive activities were investigated by wound healing and in vitro invasion assays. Western blot analysis was also applied to analyze protein expression levels associated with EMT and their upstream transcription factors in Huh7 cells. Results : TOWE and TOEE treatment potently inhibited migration and invasion of Huh7 cells compared to the untreated group. Both extracts treatment inhibited protein expression levels of N-cadherin, matrix metalloproteinase (MMP)-9, and vimentin while E-cadherin was significantly accelerated. In addition, the activated status of transcription factors, Snail, nuclear factor (NF)-κ B, and zinc finger E-box binding homeobox (ZEB)1 was also inhibited with statistical significance. In comparison to both extracts, TOEE more potently attenuated migration, invasion, and EMT markers as well as their transcription factors in Huh7 cells than TOWE, which means that TOEE might possess more functional phytochemicals than TOWE. Conclusion : Consequently, TOWE and TOEEattenuated metastatic activity of hepatocellular carcinoma through the regulation of EMT markers and their transcription factors in Huh7 cells, which means that T. officinale might be a promising strategy for a chemopreventive agent against HCC metastasis.