• Title/Summary/Keyword: material development

Search Result 9,044, Processing Time 0.042 seconds

Anti-metastatic Activity of Water Extract of Samguikoeuitang via Enhancement of Natural Killer Cells (삼귀고의탕 물추출물의 자연살해세포 활성을 통한 항전이효과)

  • Ko, Hyun-Suk;Park, Moon-Nyeo;Kim, Bong-Lee;Yoon, Taek-Joon;Song, Hyo-Sook;Cho, Sung-Yun;Lee, Hyo-Jung;Lee, Hyo-Jeong;Jeong, Soo-Jin;Lee, Eun-Ok;Kim, Sung-Hoon
    • Journal of Korean Traditional Oncology
    • /
    • v.15 no.1
    • /
    • pp.29-36
    • /
    • 2010
  • The anti-metastatic activity of water extract of Samguikoeuitang (WSGKE) consisting of Ginseng Radix, Angelicae Radix, Sophora flavescens and Coicis Semenwas examined. Ethanol extract of Samguikoeuitang (ESGKE) showed significant cytotoxicity against colon 26-M3.1 carcinoma cells, while WSGEK did not. However, WSGKE significantly increased the production of IL-6 and IL-12 in thioglycollate-induced macrophages from Balb/c mice, whereas ESGKE did not. WSGKE significantly increased natural killer (NK) cell cytotoxicity against effecter YAC-1 cells in an Effecter cells/Target ratio dependent manner. Also, WSGKE significantly suppressed lung metastasis after i.v. injection of colon26-M3.1 carcinoma cells. Inhibitory effect of WSGKE on lung metastasis totally abolished in NK cells-deficient mice by treatment with anti-asialo GM1 serum. In addition, the combination treatment of cisplatin and WSGKE (100 ${\mu}g$/mouse) prolonged the lifespan of mice inoculated by colon26-M3.1 cell. These findings suggest that WSGKE can inhibit lung metastasis and prolong life span via immunological enhancement as a Biological Response Modifier.

  • PDF

The Design Development of Korean Paper Fashion Material through Manual Work (수작업을 통한 한지 패션 소재 디자인 개발)

  • Byun, Mi-Yeon;Lee, In-Seong
    • Korean Journal of Human Ecology
    • /
    • v.17 no.6
    • /
    • pp.1205-1213
    • /
    • 2008
  • Material is a factor for maximizing formative aspect among fashion design factors. Therefore, central axis of modern fashion is performing various trials for escaping from existing cloth and searching for artistic value. Especially, Korean paper is a formative material, which is manufactured through traditional manual work in Korea. The material is used in various fields on the basis of its aesthetic feature. Especially, fashion field performs handcraft activity on the basis of mulberry pulp, which is a prime material of Korean paper. Because the activity can be reinterpreted by world designers, who want to find motive of fashion material in the third world, it is necessary to perform experimental study for developing expressive form on the basis of diversity of Korean paper material. Therefore, the purpose of this study is to perform experimental study by focusing on the development of Korean paper material in order to express formative feature. The study purposes are as follows. The first purpose is to reinterprete the theory through actual work of fiber formation using Korean paper in the current flow where art and design field are fused and compromised. The second purpose is to suggest vision of material development on the basis of formative feature to fashion world focusing its eyesight to Asia and the third countries. The study results are as follows. First, Korean paper has been evaluated as proper material for the fusion of design and art because of its handicraft feature, long-term preservation, heat insulation, absorption, diversity and eastern feature. Second, the study performed various trials for artistic dress material by developing 12 Korean paper works and suggested the development of new material on the basis of formative feature of modem fashion industry.

Proposal of a prototype plant based on the exfoliation process for the treatment of irradiated graphite

  • Pozzetto, Silvia;Capone, Mauro;Cherubini, Nadia;Cozzella, Maria Letizia;Dodaro, Alessandro;Guidi, Giambattista
    • Nuclear Engineering and Technology
    • /
    • v.52 no.4
    • /
    • pp.797-801
    • /
    • 2020
  • Most of irradiated graphite that should be disposed comes from moderators and reflectors of nuclear power plants. The quantity of irradiated graphite could be higher in the future if high-temperature reactors (HTRs) will be deployed. In this case noteworthy quantities of fuel pebbles containing semi-graphitic carbonaceous material should be added to the already existing 250,000 tons of irradiated graphite. Industry graphite is largely used in industrial applications for its high thermal and electrical conductivity and thermal and chemical resistance, making it a valuable material. Irradiated graphite constitutes a waste management challenge owing to the presence of long-lived radionuclides, such as 14C and 36Cl. In the ENEA Nuclear Material Characterization Laboratory it has been successfully designed a procedure based on the exfoliation process organic solvent assisted, with the purpose of investigate the possibility of achieving graphite significantly less toxic that could be recycled for other purpose [1]. The objective of this paper is to evaluate the possibility of the scalability from laboratory to industrial dimensions of the exfoliation process and provide the prototype of a chemical plant for the treatment of irradiated graphite.

A Study of Echo Reduction of Underwater Acoustic Material Considering Ocean Condition (수중환경을 고려한 수중 음향재료의 반향음 감소성능 연구)

  • Seo, Young Soo;Ham, Il Bae;Jung, Woo Jin
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2014.10a
    • /
    • pp.377-384
    • /
    • 2014
  • The requirement of acoustic material which is used in underwater environment more increases. The material is used to reduce acoustic signature and radiate noise for underwater vehicle. Underwater acoustic material was made by viscoelastic material such as a rubber and a polyurethane etc. The mechanical and acoustic characteristics of these material change with hydrostatic pressure. In order to increase an acoustic performance according to hydrostatic pressure, several kinds of scatterers were added to viscoelastic material. In this paper, acoustic modelling and analysis techniques of underwater acoustic material with hydrostatic pressure were introduced and proposed. The specimens for pulse tube test were made and echo reductions were calculated and measured with hydrostatic pressure. Also the characteristics of echo reduction of the specimens with hydrostatic pressure were obtained and discussed.

  • PDF

A Study on the Echo Reduction Performance of Underwater Acoustic Material (수중 음향재료의 반향음 감소성능 연구)

  • Seo, Young Soo;Ham, Il Bae;Jung, Woo Jin
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.24 no.11
    • /
    • pp.868-875
    • /
    • 2014
  • The requirement of acoustic material which is used in underwater environment more increases. The material is used to reduce acoustic signature and radiate noise for underwater vehicle. Underwater acoustic material was made by viscoelastic material such as rubber and polyurethane etc. The mechanical and acoustic characteristics of these material change with hydrostatic pressure. In order to improve an acoustic performance according to hydrostatic pressure, several kinds of scatterers were added to viscoelastic material. In this paper, acoustic modelling and analysis techniques of underwater acoustic material with hydrostatic pressure were introduced and proposed. The specimens for pulse tube test were made and echo reductions were calculated and measured with hydrostatic pressure. Also the characteristics of echo reduction of the specimens with hydrostatic pressure were obtained and discussed.

Correlation between Dielectric Constant Change and Oxidation Behavior of Silicon Nitride Ceramics at Elevating Temperature up to 1,000 ℃ (질화규소 세라믹스의 고온(~1,000 ℃) 유전상수 변화와 산화 거동의 상관관계 고찰)

  • Seok-Min, Yong;Seok-Young, Ko;Wook Ki, Jung;Dahye, Shin;Jin-Woo, Park;Jaeho, Choi
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.25 no.6
    • /
    • pp.580-585
    • /
    • 2022
  • In this study, the high-temperature dielectric constant of Si3N4 ceramics, a representative non-oxide-based radome material, was evaluated and the cause of the dielectric constant change was analyzed in relation to the oxidation behavior. The dielectric constant of Si3N4 ceramics was 7.79 at room temperature, and it linearly increased as the temperature increased, showing 8.42 at 1,000 ℃. As results of analyzing the microstructure and phase for the Si3N4 ceramics before and after heat-treatment, it was confirmed that oxidation did not occur at all or occurred only on the surface at a very insignificant level below 1,000 ℃. Based on this, it is concluded that the increase in the dielectric constant according to the temperature increase of Si3N4 ceramics is irrelevant to the oxidation behavior and is only due to the activation of charge polarization.

Analysis of pipe thickness reduction according to pH in FAC facility with In situ ultrasonic measurement real time monitoring

  • Oh, Se-Beom;Kim, Jongbeom;Lee, Jong-Yeon;Kim, Dong-Jin;Kim, Kyung-Mo
    • Nuclear Engineering and Technology
    • /
    • v.54 no.1
    • /
    • pp.186-192
    • /
    • 2022
  • Flow accelerated corrosion (FAC) is a type of pipe corrosion in which the pipe thickness decreases depending on the fluid flow conditions. In nuclear power plants, FAC mainly occurs in the carbon steel pipes of a secondary system. However, because the temperature of a secondary system pipe is over 150 ℃, in situ monitoring using a conventional ultrasonic non-destructive testing method is difficult. In our previous study, we developed a waveguide ultrasonic thickness measurement system. In this study, we applied a waveguide ultrasonic thickness measurement system to monitor the thinning of the pipe according to the change in pH. The Korea Atomic Energy Research Institute installed FAC-proof facilities, enabling the monitoring of internal fluid flow conditions, which were fixed for ~1000 h to analyze the effect of the pH. The measurement system operated without failure for ~3000 h and the pipe thickness was found to be reduced by ~10% at pH 9 compared to that at pH 7. The thickness of the pipe was measured using a microscope after the experiment, and the reliability of the system was confirmed with less than 1% error. This technology is expected to also be applicable to the thickness-reduction monitoring of other high-temperature materials.