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Changes of Plasma Lidocaine Concentrations after Stellate Ganglion Block according to Volume-changes of 1% Lidocaine (성상신경절차단시 주입된 1% Lidocaine 양에 따른 혈중 Lidocaine 농도 변화)

  • Song, Sun-Ok;Suh, Yung-Ho
    • The Korean Journal of Pain
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    • v.14 no.1
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    • pp.26-31
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    • 2001
  • Background: Sympathetic blocks with local anesthetics are used to differentiate sympathetically- maintained pain (SMP) from sympathetically-independent pain (SIP). However, systemic lidocaine is also used in the management of neuropathic pain. Therefore, there may be possibility of a false positive response in relieving their pain by systemic absorption of lidocaine following a diagnostic sympathetic block in patients with SIP. In this study, we measured the plasma lidocaine concentrations after a stellate ganglion block (SGB) using three volumes of 1% lidocaine. Methods: This prospective, crossover study was performed in 3 patients who experience sudden hearing loss and in 4 volunteers. Each person received SGB three times using three different volumes (6 ml, 12 ml and 16 ml) of 1% lidocaine at one week intervals. SGB was performed using a 23 G butterfly needle via a paratracheal approach by two persons. Two ml of venous blood was obtained from a prepared contra-lateral sided venous route at 1, 3, 5, 7, 10, 20 and 60 min after SGB. Plasma lidocaine level was analyzed by immunoassay. Results: Mean plasma lidocaine concentrations correlated well with the volumes of 1% lidocaine used in SGB; larger volumes showed higher concentrations (P < 0.01). Mean peak plasma concentrations were $1.08{\pm}0.18$ in 6 ml, $1.90{\pm}0.47$ in the 12 ml and $2.74{\pm}0.67{\mu}g/ml$ in the 16 ml groups (P < 0.01). The mean time to reach peak plasma concentration was not significantly different between the three groups. Conclusions: The peak plasma lidocaine concentrations in SGB using large volume were found to be similar to that of IV lidocaine infusion in the management of neuropathic pain. These data suggest that diagnostic sympathetic block may result in many false positive responses for SMP. Part of its effect may be related to systemic local anesthetic absorption and not to a sympathetic block. Therefore, physicians may be required to use optimal volumes and minimal concentration of local anesthetic in diagnostic sympathetic block procedures and also make a careful assessment of the performance of a permanent sympathetic block.

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Primary Closure of Deep Penetrating Wounds under Local Anesthesia with Dental Lidocaine HCL 28 Ampules in Maxillofacial Regions -Report of two cases - (치과용 Lidocaine 28 앰플로 국소마취 하에 1차 봉합한 악안면 심부 관통성 열창 -증례 보고-)

  • Kim, Jong-Bae;Yoo, Jae-Ha
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.1 no.1 s.1
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    • pp.26-31
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    • 2001
  • The wide deep penetrating wound of maxillofacial region should be early closed under emergency general anesthesia for the prevention of complications of bleeding, infection, shock & residual scars. But, if the emergency general anesthesia wound be impossible because of pneumoconiosis, obstructive pulmonary disease & hypovolemic shock, early primary closure should be done under local anesthesia by use of much amount of the anesthetic solution. The maximum dose of dental lidocaine (2% lidocaine with 1 : 100,000 epinephrine) is reported to 7 mg/kg under 500 mg (13.8 ampules) in normal adult. But the maximum permissible dose of dental lidocaine can be changed owing to the general health, rapidity of injection, resorption, distribution & excretion of the drug. The blood level of overdose toxicity is above $4.0{\mu}g/ml$ in central nervous & cardiovascular system. The injection of dental lidocaine 1-4 ampules is attained to the blood level of $1{\mu}g/ml$ in normal healthy adult. The duration of anesthetic action in the dental 2% lidocaine hydrochloride with 1 : 100.000 epinephrine is 45 to 75 minutes and the period to elimination is about 2 to 4 hours. Therefore, authors selected the following anesthetic methods that the first injection of 6 ampules is applied into the deeper periosteal layer for anesthetic action during 1 hour, the second injection into the deeper muscle & fascial layer, the third injection into the superficial muscle and fascial layer, the fourth injection into the proximal skin & subcutaneous tissue and the fifth final injection into the distal skin & subcutaneous tissue. The total 26-28 ampules of dental lidocaine were injected into the wound as the regular time interval during 5-6 hours, but there were no systemic complications, such as, agitation, talkativeness, convulsion and specific change of vital signs and consciousness.

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Effect of food waste properties on methane production (음식물쓰레기의 특성이 메탄생성량에 미치는 영향분석)

  • Lee, Soo Gwan;Choi, Hong Lim;Lee, Joon Hee
    • Journal of the Korea Organic Resources Recycling Association
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    • v.22 no.3
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    • pp.11-22
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    • 2014
  • The buffer capacity of food waste lowers during the collecting and transportation period. Food waste usually shows deficiency of micro nutrients especially molybdenum(Mo) and cobalt(Co). Therefore, food waste can be considered as a good mixture of livestock waste to enhance methane production. The objective of this study was to investigate the correlation between properties of substrates (local food waste and livestock manure) and methane yields for successive anaerobic fermentation process and its stable management. Food wastes were taken at an intermediate storage or treatment system provided by eight local authorities (Gangnam, Gangdong, Gwanak, Guro, Dongjak, Songpa, Yeongdeungpo, and Younsan) in Seoul. The solid content and potential methane yield of food wastes were average of 16% and $446.6STP-m{\ell}/g-VS$ (range from 334.8 to $567.5STP-m{\ell}/g-VS$) respectively. As for the beef cattle manure, the solid content and potential methane yield had an average of 26% and $280.6STP-m{\ell}/g-VS$ respectively. Potential methane yield had a positive correlation with fat content, and hydrogen content and a negative correlation with carbohydrate content ($r^2&gt;0.8$). Therefore, the potential methane yield can be predicted based on the substrate characterization results with reasonable accuracy. Further research may be needed to investigate the relation of the properties of the mixture substrate and methane production rate. The mixtures may include food waste, livestock waste, and bulking agents (saw dust, rice hull, or agricultural byproducts etc.) to determine best combination of these substrates for maximum methane production rate.

Contents of Di-(2-ethylhexyl) Phthalate in PVC Food Packaging (In 2000-2002 and 2004) (유통 PVC 식품포장재 중의 DEHP 함량(2000-2002년, 2004년))

  • Yoon Mi-Hye;Eom Mi-Na;Kim Ki-Cheol;Jung Hong-Rae;Jeong Il-Hyeong;Do Young-Sook;Kim Jae Gwan;Kim Young-Suk;Ko Hoan-Uck;Son Jin-Seok
    • Journal of Food Hygiene and Safety
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    • v.20 no.4
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    • pp.199-204
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    • 2005
  • Three hundred sixty-eight samples of domestic PVC food packaging were analyzed fir DEHP(di-(2-ethyhexyl) phthalate) used in plasticizer by GC/FID and GC/MSD. The number of samples collected were 47(2000), 143(2001), 88(2002) and 89(2004) from local markets in Gyeonggi-Do. In $2000\∼2001$, DEHP was highly detected in 86 out of 190 samples and the level of DEHP were ranged from 1.3 g/kg to 82.8 g/kg. In 2002, meanwhile, DEHP was detected in 8 out ot 88 samples and the level of DEHP were shown to from 1.3 g/kg to 51.5 g/kg. In 2004, DEHP was detected in only one out of 89 samples and the amount was 30.5 g/kg. As a result of this study, it was made clear that the detection rates of DEHP in PVC food packaging were rapidly decrease every year.

Shelf-life and Quality Characteristics of Potassium Sorbate-free Meat Products (솔빈산 칼륨이 첨가되지 않은 육제품의 저장 수명과 품질 특성)

  • 이근택;황보식;정구용
    • Food Science of Animal Resources
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    • v.18 no.2
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    • pp.107-114
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    • 1998
  • This study aimed for the examination of quality characteristics and safety of potassium sorbate-free meat products. Therefore, experiments were carried out on the frankfurter sausage and pressed ham, which were stored at 4 and 30$^{\circ}C$ for up to 40 days. The potassium sorbate concentrations of the frankfurter sausage and pressed ham obtained from local market ranged from 1.087 to 1.449g / kg, which were below the permitted value as prescribed in the Korean Hygienic Regulation. At the 0 day the total aerobic bacterial counts of frankfurter sausage and pressed ham were in the level of around 103.0 and 103.4 CFU / g, respectively. However, they were prominently increased after 20 days at 4$^{\circ}C$ and 10 days at 30$^{\circ}C$ to higher than 105 CFU / g. After 30 days the counts were increased to 106.5 and 107.2 CFU / g, respectively. The growth curve of lactic acid bacteria was shown to be similar with that of total bacteria. the counts of lactic acid bacteria of the products stored at 4$^{\circ}C$ were 101∼102 CFU / g lower than those stored at 30$^{\circ}C$. Coliform bacteria was not detected in both of the products stored at 4$^{\circ}C$ even after 40 days storage, but after 10 days at the 30$^{\circ}C$. No significant differences in the microbial counts examined in this study were observed between frankfurter sausage and pressed ham. The biochemical tests on the isolated colonies from Clostridein agar showed no presence of Clostridium botulinum and Clostridium perfringens in the meat products examined. The pH of frankfurter sausage and pressed ham at the beginning was about 6.6, which level was maintained relatively constant during the storage at 4$^{\circ}C$, but it was increased after decrease to about 5.5 during the storage at 30$^{\circ}C$. TBA value was increased slightly till 30 days, but after that time increased sharply. VBN value was increased slowly during the whole storage, but it was more than 30 mg% for the samples stored at 30$^{\circ}C$.

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Mid-IR Luminosity Functions of Local Galaxies in the North Ecliptic Pole Field

  • Kim, Seong Jin;Lee, Hyung Mok;Jeong, Woong-Seob
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.1
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    • pp.72.3-72.3
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    • 2015
  • We present the mid-infrared (MIR) luminosity function (LF) of local (z < 0.3) star forming (SF) galaxies based on the AKARI's NEP-Wide Survey data. We utilized a combination of the NEP-Wide point source catalogue containing a large number (114,000) of infrared (IR) sources distributed over the wide (5.4 sq. deg) field and spectroscopic redshift (z) data for 1790 selected targets obtained by optical follow-up surveys with MMT/Hectospec and WIYN/Hydra. The AKARI's continuous $2{\sim}24{\mu}m$ wavelength coverage and the spectroscopic redshifts for sample galaxies enable us to derive accurate spectral energy distributions (SEDs) in the mid-infrared. We carried out SED-fit analysis and employed 1/Vmax method to derive the mid-IR (e.g., $8{\mu}m$, $12{\mu}m$, and $15{\mu}m$ rest-frame) luminosity functions. Our results for local galaxies from the NEP region generally consistent with various previous works for other fields over wide luminosity ranges. The comparison with the results of the NEP-Deep data implies the luminosity evolution from higher redshifts towards the present epoch. We attempted to fit our derived LFs to the double power-laws and present the resulting power indices. We also examined the correlation between mid-IR luminosity and total IR luminosity.

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A Intervention of Meridian-blocking with Local Pressure on Therapeutic Effect of GB30 Electroacupuncture in Chronic Monoarthritic rats (경락 압박이 만성관절염에서의 환도 전침 치료 효과에 미치는 영향)

  • 박히준;이향숙;손양선;류연희;진수희;인창식;한제생;임사비나;이혜정
    • The Journal of Korean Medicine
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    • v.23 no.1
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    • pp.92-99
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    • 2002
  • Objectives : To investigate the role of Meridian flow on acupuncture effect, we observed the therapeutic effects of electroacupuncture (EA) after Meridian blocking with pressure in arthritic rats. Methods : To make reliable and local monoarthritis, $40{\;}{\mu}l$ complete Freund's adjuvant was injected into the tibio-tarsal joint. EA was applied on acupoint GB30 while 5 Pascal pressure was added to the middle of the Gall bladder Meridian around GB31 between acupoint GB30 and arthritic foci (ipsilateral meridian blocking: IB) or opposite part of IB (contralateral part blocking: CB). To observe the change of arthritis, extension and flexion pain scores and circumferential differences were evaluated once a week. Results : EA stimulation without blocking reduced arthritic pain significantly. IB abolished the acupuncture effects and there was no statistical difference with the arthritic control group, whereas the CB group still showed the therapeutic effects of acupuncture. Conclusions : This finding strongly supports that the Meridian blocking with local pressure reduced the therapeutic effect of EA.

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Estimation of evapotranspiration change due to the 2019 April Gangwon-do wildfire using remote-sensing data

  • Kim, JiHyun;Sohn, Soyoung;Kim, Yeonjoo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.4-4
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    • 2020
  • Three wildfires severely damaged local towns and forests in Gangwon-do, South Korea in 2019 April 4-5. Local hydrological regime could be greatly altered by the wildfires, therefore it is important to assess its damage (e.g. area and severity) and also resultant changes in hydrological fluxes. We retrieved the Normalized-Burned Ratio (NBR) index using remote-sensing data (Moderate Resolution Imaging Spectroradiometer (MODIS) 500-m 8-day surface reflectance data), and delineated the damaged-area based on the difference in the NBR (dNBR) before and after the wildfires. We then estimated changes in the annual evapotranspiration (AET) in 2019 using the MODIS evapotranspiration data (500-m 8-day). It was found that the damaged-area of the three wildfires was 29.50 km^2 in total, which take up 1.00-6.19% area of five catchments. It was estimated that the AET would be decreased as 0.05-1.56% over those five catchments, as compared to the pre-fire AET (2004-2018). The impact of the wildfires on the catchment AET was less severe than expected (i.e. up to 1.56%) mostly because two big wildfires were distributed across two catchments respectively (i.e. four catchments for the two wildfires) and the other wildfire was small and not severe. This study highlights the importance of assessing the area and severity of a wildfire when estimating its impact on the local hydrological cycle.

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Effects of the Seed Root Weight and the Local Varieties on the Yield and Quality of Cnidium officinale Makino root (천궁(川芎)(Cnidium officinale Makino)의 산지별(産地別) 재배종(裁培種)과 종근중(種根重)이 수량(收量) 및 품질(品質)에 미치는 영향(影響))

  • Chang, Sang Moon;Choi, Jyung;Jyung, Sang Hwan;Shu, Dong Hwan
    • Current Research on Agriculture and Life Sciences
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    • v.6
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    • pp.87-91
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    • 1988
  • We studied the effects of the seed root weight and the local varieties on the yield and the quality of Cnidium officinale Makino root. The fresh and dried root weight per plant was found to be 92.7 g and 18.5 g in the large seed root(20-25 g), while 94.5 g and 17.0 g in the small seed root(15-20 g), respectively. The fresh and dried roots were produced 906.8kg/10a and 190.2kg/10a in the large seed root, but 721.2kg/10a and 165.2kg/10a in the small seed root, respectively. The root weight per plant, root yield per 10a and diethyl ether extract contents in root of Ul-Reung cultivar were higher than those of the other varieties. The root weight per plant and root yield per 10a were positively correlated with the contents of diethyl ether extracts in the large seed root, and with the ash contents of root in the small seed root. It is recommended for the high quality root production of cnidium officinale Makino to select and cultivate the large seed root(20-25 g) of Ul-Reung cultivar.

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Locational Analysis and Classification of the Eup-Settlements in the Joseon Dynasty Period from Feng-Shui's Point of View (조선시대 지방도시의 풍수적 입지분석과 경관유형- 경상도 71개 읍치를 대상으로 -)

  • Choi, Won-Suk
    • Journal of the Korean Geographical Society
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    • v.42 no.4
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    • pp.540-559
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    • 2007
  • The purpose of this paper is to analyse the locations and to interpret the landscapes of the local towns in Joseon Dynasty from Feng-shui's point of view. As a result of analysing the locations of towns in Gyeongsang Province, the towns which have typical Feng-shui landscapes make up to 58% of the total. Historically, the local towns that were established in the early period of the Joseon Dynasty didn't reveal Feng-shui's landscape, but those that were established in the late period of the Joseon Dynasty revealed the Feng-shui's landscape clearly. In this article, I classify the local towns of the Gyeongsang Province into 3 types: 1. Non Feng-shui type These towns are located near the seashore. The main reason that these towns were located at the seashore was defense against an enemy. 2. Semi Feng-shui type. These towns don't have natural location but have a man-made landscape, based on the principles of Feng-shui. 3. Typical Feng-shui type. These towns were typically administrational towns which were located at the center of a local region.