• Tuberculosis and Respiratory Diseases
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• 제61권2호
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• pp.167-170
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• 2006

대퇴골 전이를 동반한 비소세포폐암 환자에서 전이 부위에 대한 방사선 치료 후 시행한 항암화학요법 도중, gemcitabine으로 인한 방사선 회귀 피부, 근육염이 발생하였다. 대퇴부의 부종, 발적과 통증 등은 스테로이드 사용 후 모두 사라졌으며, gemcitabine 투여를 중지한 이후 현재까지 재발이 없었다.

• 한국산학기술학회논문지
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• 제21권1호
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• pp.426-438
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• 2020

본 연구의 목적은 방사선 노출 경험을 참여자의 관점에서 확인함으로써 수술실 간호사의 방사선 노출 경험에 대한 구성요소를 확인하고 의미구조를 밝히는 데 있다. 연구의 참여자는 일 광역시 종합병원 수술실에서 근무하는 간호사로 수술실 경력이 6개월 이상인 자 9명을 대상으로 하였다. 심층면담으로 자료를 수집하였고, Giorgi(2004)의 현상학적 분석 방법으로 분석하였다. 연구 결과 수술실 간호사의 방사선 노출 경험은 "반복되는 방사선 노출로 질환 발생을 걱정함", "육체적, 정신적으로 소진됨", "방사선 방어를 통해 자기보호를 하고자 노력함", "내적 혼란과 갈등을 느낌", "근무환경 개선을 요구함", "현실을 받아들이고 적응함"의 6개 구성요소로 도출 되었다. 결론으로 이들의 경험은 방사선 노출 수술에 참여하면서 질환 발생을 걱정하고 방사선 피폭과 관련된 신체적, 정신적 소진을 경험하고 갈등을 느끼면서 이직을 고려하기도 하지만 자기보호를 하고자 노력하고 현실을 받아들이고 적응하는 과정을 보였다. 본 연구결과의 바탕으로 방사선 안전 환경조성을 위해서는 조직적 차원에서 체계적으로 구체적인 해결 방법을 모색하는 것이 바람직하다고 볼 수 있다.

• Journal of Radiation Protection and Research
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• 제47권4호
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• pp.181-194
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• 2022

Internal dosimetry is a discipline which brings together a set of knowledge, tools and procedures for calculating the dose received after incorporation of radionuclides into the body. Several steps are necessary to calculate the committed effective dose (CED) for workers or members of the public. Each step uses the best available knowledge in the field of radionuclide biokinetics, energy deposition in organs and tissues, the efficiency of radiation to cause a stochastic effect, or in the contributions of individual organs and tissues to overall detriment from radiation. In all these fields, knowledge is abundant and supported by many works initiated several decades ago. That makes the CED a very robust quantity, representing exposure for reference persons in reference situation of exposure and to be used for optimization and assessment of compliance with dose limits. However, the CED suffers from certain limitations, accepted by the International Commission on Radiological Protection (ICRP) for reasons of simplification. Some of its limitations deserve to be overcome and the ICRP is continuously working on this. Beyond the efforts to make the CED an even more reliable and precise tool, there is an increasing demand for personalized dosimetry, particularly in the medical field. To respond to this demand, currently available tools in dosimetry can be adjusted. However, this would require coupling these efforts with a better assessment of the individual risk, which would then have to consider the physiology of the persons concerned but also their lifestyle and medical history. Dosimetry and risk assessment are closely linked and can only be developed in parallel. This paper presents the state of the art of internal dosimetry knowledge and the limitations to be overcome both to make the CED more precise and to develop other dosimetric quantities, which would make it possible to better approximate the individual dose.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.801-803
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• 2013

Intraduction: There is known to be a relationship between vitamin D level and more aggresive breast cancer subtypes, especially triple-negative breast cancer (TNBC). It was reported that sunlight exposure has an effect on the prognosis of patients with cancer, possibly related to the conversion of vitamin D to its active form with sunlight. We aimed to evaluate the effect of sunlight exposure on patients with TNBC. Materials-Methods: A total of 1,167 patients with breast cancer from two different regions of Turkey (Antalya and Kayseri, regions having different climate and sunlight exposure intensity over the year) were analysed retrospectively. The ratio of patients with TNBC was identified in those two regions. Results: The ratio of patients with TNBC was 8% and 12% for Kayseri and Antalya regions, respectively, and this difference between the two groups was statistically significant (p=0.021). Discussion: Sunlight exposure may be associated with more prevalent TNBC. This finding should be investigated with a prospective study.

• Journal of Radiation Protection and Research
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• 제35권1호
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• pp.12-20
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• 2010

원전 일차계통은 복잡한 수질환경으로 방사화생성물과 부식생성물 등 다양한 방사성핵종이 생성되고 있다. 이 방사성 핵종 중에서 원전종사자 피폭방사선량평가와 방사성유출물관리 측면에서 중요한 핵종으로는 $^3H,\;^{14}C,\;^{58}Co,\;^{60}Co,\;^{137}Cs,\;^{131}I$를 들 수 있다. 본 논문은 원전 방사선작업종사자와 원전 주변주민의 피폭방사선량에 기여가 큰 방사성핵종에 대해 살펴보고, 이들 핵종에 의한 선량평가 과정을 소개하였다. 특히 국내 원전에서 발생하였던 $^{131}I$ 내부피폭사건과 일차계통 냉각수의 탈염수 오염사건 등을 포함한 원전의 운영과정에서 일어났던 종사자와 원전주변주민에 대한 피폭 방사선량 평가 사례를 제시하였다. 또한 최근 이슈로 떠오른 삼중수소와 $^{14}C$의 선량평가에 대한 잠재적인 현안 등도 간단히 기술하였다.

• Journal of Radiation Protection and Research
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• 제41권4호
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• pp.424-435
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• 2016

Background: The International Commission on Radiological Protection (ICRP) recommendations and the Federal Guidance Report (FGR) published by the U.S. Environmental Protection Agency (EPA) have been widely applied worldwide in the fields of radiation protection and dose assessment. The dose conversion coefficients of the ICRP and FGR are widely used for assessing exposure doses. However, before the coefficients are used, the user must thoroughly understand the derivation process of the coefficients to ensure that they are used appropriately in the evaluation. Materials and Methods: The ICRP provides recommendations to regulatory and advisory agencies, mainly in the form of guidance on the fundamental principles on which appropriate radiological protection can be based. The FGR provides federal and state agencies with technical information to assist their implementation of radiation protection programs for the U.S. population. The system of radiation dose assessment and dose conversion coefficients in the ICRP and FGR is reviewed in this study. Results and Discussion: A thorough understanding of their background is essential for the proper use of dose conversion coefficients. The FGR dose assessment system was strongly influenced by the ICRP and the U.S. National Council on Radiation Protection and Measurements (NCRP), and is hence consistent with those recommendations. Moreover, the ICRP and FGR both used the scientific data reported by Biological Effects of Ionizing Radiation (BEIR) and United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) as their primary source of information. The difference between the ICRP and FGR lies in the fact that the ICRP utilized information regarding a population of diverse races, whereas the FGR utilized data on the American population, as its goal was to provide guidelines for radiological protection in the US. Conclusion: The contents of this study are expected to be utilized as basic research material in the areas of radiation protection and dose assessment.

• 방사선산업학회지
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• 제9권1호
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• pp.1-7
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• 2015

The trend of x-ray image sensor has been evolved from an amorphous silicon sensor to a crystal silicon sensor. A crystal silicon X-ray sensor, meaning a X-ray CIS (CMOS image sensor), is consisted of three transistors (Trs), i.e., a Reset Transistor, a Source Follower and a Select Transistor, and a photodiode. They are highly sensitive to radiation exposure. As the frequency of exposure to radiation increases, the quality of the imaging device dramatically decreases. The most well known effects of a X-ray CIS due to the radiation damage are increments in the reset voltage and dark currents. In this study, a pixel array of a X-ray CIS was made of $20{\times}20pixels$ and this pixel array was exposed to a high radiation dose. The radiation source was Co-60 and the total radiation dose was increased from 1 to 9 kGy with a step of 1 kGy. We irradiated the small pixel array to get the increments data of the reset voltage and the dark currents. Also, we simulated the radiation effects of the pixel by MCNP (Monte Carlo N-Particle) simulation. From the comparison of actual data and simulation data, the most affected location could be determined and the cause of the increments of the reset voltage and dark current could be found.

• Journal of Radiation Protection and Research
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• 제45권4호
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• pp.154-162
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• 2020

Background: Several studies have reported that wild mushrooms contain high amounts of radioactive cesium (137Cs). After the Fukushima Daiichi Nuclear Power Plant Accident, a significantly high concentration of 137Cs has been detected in wild mushrooms, and their consumption may be the cause of the chronic internal exposure of local consumers to radioactivity. Therefore, an accurate evaluation of the internal radioactivity resulting from mushroom ingestion is needed. Materials and Methods: The 137Cs elution rate through the cooking and digestion stages was evaluated using in vitro experiments. The edible mushroom Pleurotus djamor was taken as a sample for the experiments. The mushrooms were cultivated onto solid media containing 137Cs. We evaluated the internal dose based on the actual conditions using the elution rate data. For various cooking methods, the results were compared with those of other wild edible mushrooms. Results and Discussion: From the elution experiment through cooking, we proved that 25%-55% of the 137Cs in the mushrooms was released during soaking, boiling, or frying. The results of a simulated digestion experiment after cooking revealed that almost all the 137Cs in the ingested mushrooms eluted in the digestive juice, regardless of the cooking method. The committed effective dose was reduced by 20%-75% when considering the dissolution through the cooking process. Conclusion: We found that cooking lowers 137Cs concentration in mushrooms, therefore reducing the amount of radioactivity intake. Besides, since there were differences between mushroom types, we demonstrated that the internal exposure dose should be evaluated in detail considering the release of 137Cs during the cooking stages.

• 혜화의학회지
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• 제8권1호
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• pp.115-129
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• 1999

To evaluate radioprotective effects of Kamisagoonjatang(KST), Kamijihwangtang (KJT) and Kamigoonjajihwangtang(KKJT), studies were done experimentally. The results were obtained as follows: 1. By FACS analysis after exposure to radiation by Liniac, T cell and T-helper cell were significantly increased in KST treated group and also B cell and macrophage in KJT treated group while splenocytes were significantly decreased in control group. 2. WBC, PLT were significantly increased in KKJT treated group as compared with control group after exposure to radiation by Liniac. 3. In histological changes of jejunum of $BALB{\backslash}C$ mice after after exposure to radiation by Liniac, exclusion and fusion of villi were decreased in all groups as compared with control group. 4. In the observation of morphological changes by SEM and TEM after radiation by Liniac, KKJT, KJT and KST inhibited demage of internal structures such as mitochondria, ESR and golgi of jejunum cells in order as compared with control group. From above results it was concluded that KJT, KST and KKJT could be usefully applied for protection from damage by radiotherapy to cancer.

• Journal of Radiation Protection and Research
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• 제26권3호
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• pp.139-142
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• 2001

The one of important parameter involved in the calculation of internal radiation dose to the human body is the biological half-life of the radionuclide. The biological half-life is population specific and may differ from one population group to another. So the effective half-life of tritium exposure based on urinal bioassay measurement of Wolsong Nuclear Power Plants was investigated and studied.