• Macromolecular Research
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• v.15 no.2
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• pp.100-108
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• 2007

Gene therapy has become a promising strategy for the treatment of genetically based diseases, such as cancer, which are currently considered incurable. A major obstacle in the field of cancer gene therapy is the development of a safe and efficient delivery system for therapeutic gene transfer. Non-viral vectors have attracted great interest, as they are simple to prepare, stable, easy to modify and relatively safe compared to viral vectors. In this review, an insight into the strategies developed for polyethylenimine (PEI)-based non-viral vectors has been provide, including improvement of the polyplex properties by incorporating hydrophilic spacer, poly(ethylene glycol) (PEG). Moreover, this review will summarize the strategies for the tumor targeting. Specifically, a targeted polymeric gene delivery system, PEI-g-PEG-RGD, will be introduced as an efficient gene delivery vector for tumor therapy, including its functional analysis both in vitro and in vivo.

• Journal of the Korean Magnetics Society
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• v.8 no.2
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• pp.99-110
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• 1998

MR head technology from the perspective of read sensor evolution was reviewed. AMR sensors have been developed for last two decades and successfully employed into information storage devices such as disk drives. Development of manufacturable GMR sensors is of emerging technological interest because GMR sensors can further meet the need of ultrahigh recording density. In this review, the mechanisms, materials systems, operating principles of both AMR an GMR sensors, and the head structures were discuseed. Constructing GMR heads with ultrathin sensor materials and complex topographical structures demands unique fabrication and design challenges. The commercialization of GMR heads can only be realized by the succesful implementations of high performance materials, advanced thin film processes, and stable head design.

• Proceedings of the Korean Society of Computer Information Conference
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• 2017.07a
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• pp.411-412
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• 2017

쿠폰은 마케팅의 주요 전략 중 하나로 널리 이용된다. 그러나 적시적소에 제공되지 않는 쿠폰은 대부분 버려지게 된다. 본 논문은 사용자가 관광지의 어떤 관심지점에 근접했을 때, 해당 관심지점이 발행한 쿠폰정보를 능동적으로 알려주는 시스템을 개발한다. 이를 위하여, 쿠폰발행자와 이용자 등록 시스템, 쿠폰발행자의 쿠폰정보와 해당 관심지점 정보를 등록하는 시스템, 이용자들의 현재 위치를 인지하는 시스템, 이용된 쿠폰정보를 기록하는 시스템 등을 구현하였다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2017.07a
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• pp.415-416
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• 2017

본 논문은 사용자가 관광지의 어떤 관심지점에 근접했는지 사용자에게 능동적으로 알려주는 안드로이드 앱을 소개한다. 안드로이드는 관심지점에 근접했을 경우에 알람메시지를 발생하는 개발자를 위한 함수를 제공한다. 또한 GPS(Global Positioning System) 신호나 네트워크 신호를 이용하여 현재 위치를 알려주는 함수도 제공한다. 본 논문은 안드로이드가 제공하는 개발자를 위한 함수들을 이용하여 여러 가지 방법으로 관심지점 근접 상황을 인지하는 프로그램을 구현하고 이들 간의 성능을 비교한다.

• The Mathematical Education
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• v.40 no.1
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• pp.93-102
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• 2001

The world we live in is called the age of information. Thus communication and computers are doing the central role in it. When one studies the mathematical problem, the use of tools such as computers, calculators and technology is available for all students, and then students are actively engaged in reasoning, communicating, problem solving, and making connections with mathematics, between mathematics and other disciplines. The use of technology extends to include computer algebra systems, spreadsheets, dynamic geometry software and the Internet and help active learning of students by analyzing data and realizing mathematical models visually. In this paper, we explain concepts of transformation, linear transformation, congruence transformation and homothety, and introduce interesting, meaningful and visual models for teaching of a plane transformation geomeoy which are obtained by using Mathematica. Moreover, this study will show how to visualize linear transformation for student's better understanding in teaching a plane transformation geometry in classroom. New development of these kinds of teaching-learning methods can simulate student's curiosity about mathematics and their interest. Therefore these models will give teachers the active teaching and also give students the successful loaming for obtaining the concept of linear transformation.

• Korean journal of food and cookery science
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• v.22 no.6 s.96
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• pp.840-848
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• 2006

To analyse the impact of recognition for local food on frequency of visiting for local food restaurants, we surveyed 333 residents in the Kyungsangdo areas. The findings are summarized as follows. On interest of native foods, 'much' scored 40.6% and 'taste' scored 32.9%, in requirement of development. The criteria of selection of local foods was 62.3% in 'taste'. 'Institute(municipal government)' scored 31.3% as the main responsible body for the succession of local foods. The most significant criterion for tourism product of local foods was 'taste'(34.5%). The most effective way to popularize the local foods was to 'hold various kinds of cultural events'(27.5%). The necessity score on tourism product of local foods was 3.55 points. The highest recognition on native local foods was 'succession to next generation'(3.96 points). The most influential variable affecting the visit frequency toward local food restaurants was 'health factor'.

• Journal of Wetlands Research
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• v.4 no.1
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• pp.51-61
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• 2002

The wetland is a biologically integrated system consisting of water, soil, bacteria, plants, and animals. The wetland helps sustain the ecosystem, control the micro-climate and flood, maintain the ground water level, and provide fishing grounds. From the environmental standpoint, the wetland plays a vital role in reducing water pollution by filtering out sand and other polluted matters, producing oxygen, absorbing chemicals and nutrients. For these reasons, interest in restoring the wetlands has been steadily increasing. Artificial wetland, which is also referred to as created wetland or constructed wetland, is an alternative to natural wetland. Like natural wetland, artificial wetland is environmentally friendly and can effectively lower pollutant levels. The Korea government is actively reviewing the construction of artificial wetlands in mining and water supply areas to decrease nonpoint pollutant sources. This paper attempts to develop a pollutant removal model for the water quality improvement function of artificial wetlands. Artificial wetland can improve the quality of the water; however, depending on the type of water inflow, vegetation and hydrology, its effect can be different.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2002.05a
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• pp.334-341
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• 2002

As the interest in internet business increases, effective web site evaluation is in order. While web site evaluation is supposed to be based on feasible applicability and trust-worthy criteria. many researches on web site evaluation fails to rover the various business models and consider corporate-activity-related features. Besides, dealing with the limited aspects such as design and cognitive science is something to be desired on the previous researches. Therefore, This paper presents internet web site evaluation framework not only based on existing researches and analysis but also reflecting corporate strategies. The framework includes web sites contents, design, operation and management-related factors, and it is applied to companies to validate its applicability.

• Journal of Powder Materials
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• v.25 no.4
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• pp.346-354
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• 2018

Over the last decade, the study of the synthesis of semiconductor colloidal quantum dots has progressed at a tremendous rate. Colloidal quantum dots, which possess unique spectral-luminescent characteristics, are of great interest in the development of novel materials and devices, which are promising for use in various fields. Several studies have been carried out on hot injection synthesis methods. However, these methods have been found to be unsuitable for large-capacity synthesis. Therefore, this review paper introduces synthesis methods other than the hot injection synthesis method, to synthesize quantum dots with excellent optical properties, through continuous synthesis and large capacity synthesis. In addition, examples of the application of synthesized colloid quantum dots in displays, solar cells, and bio industries are provided.

• Journal of Biomedical Engineering Research
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• v.18 no.2
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• pp.127-132
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• 1997

Recently there has been increased interest in the use of iontophoresis for the transdermal delivery of drugs, both ionic and nonionic. The use of iontophoresis has been rare over the years due to the lack of domestic supplies of the instrument and the expensive iontophoresis instrument made by foreign country. The purpose of this study was to design a commercially available iontophoresis system (WIT- 1 ). The efficacy of WT- 1 system was well defined. In clinical trial, procaine iontophoresis produced local anesthesia of significantly longer duration than swabbing and placebo groups. The 4% procaine iontophoresis using WIT-1 significant difference in anesthetic duration between WIT- 1 system and IontopherTM PM system. The result of this study suggest that WIT-1 system can be used for the transdermal delivery of drugs in various clinical conditions.