• Title/Summary/Keyword: integration center

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Biochemical Characterization of a Glycosyltransferase Homolog from an Oral Pathogen Fusobacterium nucleatum as a Human Glycan-Modifying Enzyme

  • Kim, Seong-Hun;Oh, Doo-Byoung;Kwon, Oh-Suk;Jung, Jae-Kap;Lee, Yun-Mi;Ko, Ki-Sung;Ko, Jeong-Heon;Kang, Hyun-Ah
    • Journal of Microbiology and Biotechnology
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    • v.18 no.5
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    • pp.859-865
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    • 2008
  • Bacterial glycosyltransferases have drawn growing attention as economical enzymes for oligosaccharide synthesis, with their easy expression and relatively broad substrate specificity. Here, we characterized a glycosyltransferase homolog (Fnu_GT) from a human oral pathogen, Fusobacterium nucleatum. Bioinformatic analysis showed that Fnu_GT belongs to the glycosyltransferases family II. The recombinant Fnu_GT (rFnu_GT) expressed in Escherichia coli displayed the highest glycosylation activity when UDP-galactose (Gal) was used as a donor nucleotide-sugar with heptose or N-acetylglucosamine (GlcNAc) as an acceptor sugar. Interestingly, rFnu_GT transferred the galactose moiety of UDP-Gal to a nonreducing terminal GlcNAc attached to the trimannosyl core glycan, indicating its potential as an enzyme for human-type N-glycan synthesis.

Policy Suggestions for an Integration of the Family Policy Service Delivery Systems (가족정책 전달체계 통합 논의에 대한 제언)

  • Song, Hyerim;Park, Jeongyun;Chin, Meejung;Jeong, Jeeyoung
    • Journal of Family Resource Management and Policy Review
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    • v.19 no.1
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    • pp.49-71
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    • 2015
  • The purpose of this study is to make suggestions for the ongoing process of an integration of the Healthy Families Center and the Center for Multicultural Families. Based on previous studies and interview data from nine service workers at the two institutions, we make the following suggestions. First, a systematic analysis tool should be developed in order to evaluate the effects of the integration initiative with reliability and validity. Second, empirical data should be collected from the users after the integration of the two institutions and be used to promote their satisfaction. Third, a specific preparation should be made to enhance the integration process of the service workers. Fourth, the integration should be considered in the context of the community and networks. Finally, further studies are needed to understand how the integration influence family policy and social policy in larger contexts.

Wafer-Level Three-Dimensional Monolithic Integration for Intelligent Wireless Terminals

  • Gutmann, R.J.;Zeng, A.Y.;Devarajan, S.;Lu, J.Q.;Rose, K.
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.4 no.3
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    • pp.196-203
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    • 2004
  • A three-dimensional (3D) IC technology platform is presented for high-performance, low-cost heterogeneous integration of silicon ICs. The platform uses dielectric adhesive bonding of fully-processed wafer-to-wafer aligned ICs, followed by a three-step thinning process and copper damascene patterning to form inter-wafer interconnects. Daisy-chain inter-wafer via test structures and compatibility of the process steps with 130 nm CMOS sal devices and circuits indicate the viability of the process flow. Such 3D integration with through-die vias enables high functionality in intelligent wireless terminals, as vertical integration of processor, large memory, image sensors and RF/microwave transceivers can be achieved with silicon-based ICs (Si CMOS and/or SiGe BiCMOS). Two examples of such capability are highlighted: memory-intensive Si CMOS digital processors with large L2 caches and SiGe BiCMOS pipelined A/D converters. A comparison of wafer-level 3D integration 'lith system-on-a-chip (SoC) and system-in-a-package (SiP) implementations is presented.

A study of Integrated Management Center of u-City (u-City의 도시통합운영센터 구축 연구)

  • Yoo, Jae-Duck;Park, Hong-Tae;Shin, Hyun-Sik
    • The Journal of the Korea institute of electronic communication sciences
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    • v.2 no.3
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    • pp.191-198
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    • 2007
  • It needs an Integration Management Center in u-City to mange all events for an efficiency of city function, to enhance an installed infrastructure of information, and to provide u-Service like residence, administration, and culture in real time. Integration Management Center is a place to provide a city information from gathering data of communication network, traffic network, and facilities. The u-Services in Integration Management Center need an Integrated Platform to integrate verticality and horizontality between service layer. This paper study an infrastructure of Integration Operation Center and Integrated Platform. Lastly the topics are suggested how to make it a success in u-City.

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Identification and extensive analysis of inverted-duplicated HBV integration in a human hepatocellular carcinoma cell line

  • Bok, Jeong;Kim, Kwang-Joong;Park, Mi-Hyun;Cho, Seung-Hak;Lee, Hye-Ja;Lee, Eun-Ju;Park, Chan;Lee, Jong-Young
    • BMB Reports
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    • v.45 no.6
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    • pp.365-370
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    • 2012
  • Hepatitis B virus (HBV) DNA is often integrated into hepatocellular carcinoma (HCC). Although the relationship between HBV integration and HCC development has been widely studied, the role of HBV integration in HCC development is still not completely understood. In the present study, we constructed a pooled BAC library of 9 established cell lines derived from HCC patients with HBV infections. By amplifying viral genes and superpooling of BAC clones, we identified 2 clones harboring integrated HBV DNA. Screening of host-virus junctions by repeated sequencing revealed an HBV DNA integration site on chromosome 11q13 in the SNU-886 cell line. The structure and rearrangement of integrated HBV DNA were extensively analyzed. An inverted duplicated structure, with fusion of at least 2 HBV DNA molecules in opposite orientations, was identified in the region. The gene expression of cancer-related genes increased near the viral integration site in HCC cell line SNU-886.

The Basic Study of Integration for Family Welfare Delivery System : Focused on Healthy Family Support Centers and Multicultural Family Support Centers (가족복지전달체계 통합을 위한 기초연구 : 건강가정지원센터와 다문화가족지원센터를 중심으로)

  • Lee, Seong-Mie;Song, Hyerim;Ra, Hui-Mun;Park, Jeong-Yoon
    • Journal of Families and Better Life
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    • v.30 no.5
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    • pp.1-15
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    • 2012
  • The purpose of this study is various discussion and alternatives focusing on integration of center for enhancing family policy delivery system and family support service the long term. The subject is managers who work at Healthy Family Support centers and Multicultural Family Centers. And they are responded non-structural questionnaire. The results were follows: First, 82.4% respondents of healthy support center and 50% respondents were in favor of integration. Second, reason of integration are conformance for social integration, the efficiency of center operations, the adequacy of program for various family, doing program with the goal of both centers of the similarity, complementary, and user convenience, prevent duplication and missing of services and so on, If the amount charged against the project of the center dissimilarity of institutions, including the operating direction was different. Third, the Center for the meaning of integration are name, organization, reorganization or consolidation of functions, was regarded as entrusted to corporate consolidation. Fourth, the consolidation that occurs during problem solving to ensure the succession of budgeting and human resources and program alternative for dressing up, commissioning center was the difference as problem solving.

Solid Propellants for Propulsion System Including a Yellow Iron Oxide (황색산화철을 포함하는 혼합형 추진제의 특성에 관한 연구)

  • Park, Sungjun;Won, Jongung;Park, Jungho;Park, Euiyong;Choi, Sunghan
    • Journal of the Korean Society of Propulsion Engineers
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    • v.22 no.3
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    • pp.65-71
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    • 2018
  • There is no significant difference in the initial viscosity of a propellant applied with yellow iron oxide and red iron oxide. In addition, the thermal decomposition rate of the material with added yellow iron oxide is faster than that with the addition of red iron oxide. Specifically, it was confirmed that the pressure exponent was 18% lower at high temperature and high pressure with yellow iron oxide than with red iron oxide. The initial viscosity was lowest at 71% of the large particle to small particle ratio.

Employees' experiences of integrated services in Healthy Family and Multicultural Family Support Centers in Seoul (서울지역 건강가정·다문화가족지원센터 종사자의 통합서비스 운영 경험)

  • Son, Seohee;Kim, Mi Young
    • Journal of Family Resource Management and Policy Review
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    • v.23 no.4
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    • pp.1-21
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    • 2019
  • The purpose of this study was to explore employees' experiences of integrated services in Healthy Family and Multicultural Family Support Centers in Seoul. In-depth interviews were conducted with seven employees, including managers and heads of Healthy Family and Multicultural Family Support Centers. The interviews identified three themes: the direction of integrated service, the characteristics of the integration process, and the challenges of integrated service. For the direction of integrated service, the participants identified the integration center as a professional family services organization that provided customized services for different types of families. During the integration process, employees found it difficult to provide integrated services because few guidelines existed on operating an integration center that provided services to families with different characteristics and needs. However, they also explained positive aspects of integration, such as strengthening the business's capacity by expanding the organization. To improve integrated service, employees emphasized the expertise and appropriateness of the family services over the efficiency of the integration centers. They also stressed expansion as a role of a professional family services organization. These findings suggested that establishing a clear direction for integrated service as well as the roles of administrative support agencies is important for activating integrated services.

MOBILE FRAMEWORK FOR INTEGRATED 4S DATA

  • Oh, Byoung-Woo;Kim, Mi-Jeong;Lee, Eun-Kyu;Kim, Min-Soo
    • Proceedings of the KSRS Conference
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    • 2002.10a
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    • pp.838-843
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    • 2002
  • Recently, PDA and cellular phone with color LCD have been widely used in various fields by high efficiency and micro miniaturization technology. According to maturity of these mobile environments, user request about mobile application field is increased. Mobile applications provide various information which is concerned with user's position through cable and wireless transmission. This paper discusses the issues related to the mobile framework for integrated 4S data. The integrated 4S data mean spatial data fusion on GIS, SIIS, ITS, and GNSS. The mobile framework provides not only spatial data but also location services such as reverse geocoding, directory service, etc. It consists of client subsystem, service provider, and data provider.

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Using Canadian Occupational Performance Measure - On the Effects of Sensory Integration Treatment to the Daily-Life Task Performance of a Child with a Cerebral Palsy (감각통합치료가 뇌성마비 아동의 일상생활 기능에 미치는 효과 - 캐나다 작업수행 측정을 이용하여 -)

  • Kwon, Boon-Jung;Park, Ji-Young
    • The Journal of Korean Academy of Sensory Integration
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    • v.1 no.1
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    • pp.53-59
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    • 2003
  • Objective : The objective of this case study is to search the effects of sensory integration treatment. First we have taken a child with a cerebral palsy and given him/her sensory integration treatment. Then, we intended to look into whether the child performed his daily-life tasks and how satisfactory the parents were with the treatment. Methods : We have chosen a child with a cerebral palsy and tested his sensory integration functions. Applying the 30 minutes-sensory integration treatment twenty times to the child, we compared the result of the treatment using Canadian Occupational Performance Measure. We counseled the parents of the child before and after the treatment. Results : We have rated the problems with the degrees of importance referring to the parents. Important problems include controlling eliminations, having meals, moving by self, interacting with peer groups, and performing delicate hand-movements. The score of the in the performance is 1.2 and the score of the degree in the satisfaction is 1.4 compared with the total score. Conclusion : We have concluded that the sensory integration treatment has the effective result to the daily-life task performances of a child with a cerebral palsy, a kind of sensory integration dysfunction and satisfies the child's parents after this case study.

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