• Applied Microscopy
• /
• v.51
• /
• pp.6.1-6.9
• /
• 2021

Histopathology is a well-established standard diagnosis employed for the majority of malignancies, including breast cancer. Nevertheless, despite training and standardization, it is considered operator-dependent and errors are still a concern. Fractal dimension analysis is a computational image processing technique that allows assessing the degree of complexity in patterns. We aimed here at providing a robust and easily attainable method for introducing computer-assisted techniques to histopathology laboratories. Slides from two databases were used: A) Breast Cancer Histopathological; and B) Grand Challenge on Breast Cancer Histology. Set A contained 2480 images from 24 patients with benign alterations, and 5429 images from 58 patients with breast cancer. Set B comprised 100 images of each type: normal tissue, benign alterations, in situ carcinoma, and invasive carcinoma. All images were analyzed with the FracLac algorithm in the ImageJ computational environment to yield the box count fractal dimension (Db) results. Images on set A on 40x magnification were statistically different (p = 0.0003), whereas images on 400x did not present differences in their means. On set B, the mean Db values presented promising statistical differences when comparing. Normal and/or benign images to in situ and/or invasive carcinoma (all p < 0.0001). Interestingly, there was no difference when comparing normal tissue to benign alterations. These data corroborate with previous work in which fractal analysis allowed differentiating malignancies. Computer-aided diagnosis algorithms may beneficiate from using Db data; specific Db cut-off values may yield ~ 99% specificity in diagnosing breast cancer. Furthermore, the fact that it allows assessing tissue complexity, this tool may be used to understand the progression of the histological alterations in cancer.

• Transactions on Electrical and Electronic Materials
• /
• v.17 no.5
• /
• pp.306-309
• /
• 2016

The Cs₃Sb photocathode was formed by non-vacuum process technology. An in-situ vacuum device was fabricated successively with flat cesium antimonide photocathode emitters fabricated in a process chamber. The electrical properties of the device were characterized. Electron emission from the devices was induced by photoemitted electrons, which were accelerated by an anode electric field that was shielded from the photoemitter surface. The electrical characteristics of the devices were investigated by measuring the anode current as a function of device operation times with respect to applied anode voltages. Planar blue LED light with a 450 nm wavelength was used as an excitation source. The results showed that the cesium antimonide photocathode emitter has the potential of long lifetime with stable electron emission characteristics in panel devices. These features demonstrate that the cesium antimony photocathodes produced by non-vacuum processing technology is suitable for flat cathodes in panel device applications.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.29 no.4
• /
• pp.241-246
• /
• 2016

ZnO thin films have wide application areas due to its versatile properties as transparent conductors, wide-bandgap n-type semiconductors, gas sensor materials, and etc. We have performed a systematic investigation on ultraviolet-assisted CVD (chemical vapor deposition) method. Ultraviolet irradiation during the deposition of ZnO causes chemical reduction on the growing surface; which results in the reduction of the deposition rate, increase in the surface roughness, and decrease of the electrical resistivity. These effects produce larger characteristic variation with various deposition conditions in terms of surface morphology and optical/electrical properties compared to normal CVD deposited ZnO thin films. This versatile controllability of ultraviolet-assisted CVD can provide a larger processing options in the fabrication of nano-structured materials and flexible device applications.

• Proceedings of the Mineralogical Society of Korea Conference
• /
• 2005.05a
• /
• pp.50-57
• /
• 2005

Although the bulk composition of materials is one of the major considerations in extractive metallurgy and environmental science, surface composition and topography (edges and dislocations are preferred sites for physicochemical reactions) control surface reactivity, and consequently play a major role in determining metallurgical phenomena and pollution by heavy metals and organics. An understanding of interaction mechanisms of different chemical species with the mineral surface in an aqueous media is very important in natural environment and metallurgical processing. X-ray photoelectron spectroscopy (XPS) has been used as an ex-situ analytical technique, but the material to be analyzed can be any size from $100{\mu}m$ up to about 1 cm. It can also measure mixed solids powders, but it is impossible to ascertain the original source of resulting x-ray signals where they were emitted from, since it radiates and scans the macro sample surface area.

• Proceedings of the Korean Powder Metallurgy Institute Conference
• /
• 2006.09b
• /
• pp.716-717
• /
• 2006

Gas release behavior from aluminum and Al 7075 alloy powders during heating in argon was investigated by in-situ gas chromatography. Water vapor, hydrogen, carbon mono-oxide were detected as individual evolution spectra against heating temperature and time. The mechanisms of water and hydrogen evolutions were studied in detail for the determination of effective degassing condition. Magnesium in the alloy powder was found to lower the hydrogen evolution temperature to enhance overall hydrogen release.

• Proceedings of the Korean Powder Metallurgy Institute Conference
• /
• 2006.09a
• /
• pp.309-310
• /
• 2006

Porous titanium implants can be produced by powder metallurgy in combination with suitable space holder materials. Various mechanical experiments were done to characterize this material regarding the influence of the processing parameters on microstructure and mechanical properties taking into account the properties of the human bone. In this paper, the anistropic behaviour of uniaxially compacted samples was analysed in compression tests and compared to the behaviour of isostatically pressed samples. The failure of the struts of the porous titanium and the crack- initiation and -growth was examined by in-situ SEM analysis.

• Transactions on Electrical and Electronic Materials
• /
• v.18 no.3
• /
• pp.176-179
• /
• 2017

Non-vacuum processing technology was used to produce $Cs_3Sb$ photocathodes on substrates and fabricate in-situ panel devices. Electrical properties of these panel devices were characterized by measuring anode current and charge dose as functions of devices operation time. An excitation light source with a 475 nm wavelength was used for photocathodes. Results showed that emission properties of these photocathode emitters depended heavily on the vacuum level of these devices and that $Cs_3Sb$ flat emitters had the potential of operating for a long lifetime with stable electron emission characteristics via re-cesiation process in the panel device. These features make $Cs_3Sb$ photocathodes suitable as flat emitters in panel device applications.

• Journal of the Korean Society for Precision Engineering
• /
• v.4 no.3
• /
• pp.60-68
• /
• 1987

An optoelectronical method for in process monitoring of flank wear of cutting tools is presented. The method is based upon real-time vision technology in which the tool is illuminated by a beam of laser and then the image of wear zone is taken by a vidicon camera. The image is converted to a series of digital pixel data and processed through an algorithm specially developed for measurement of the wear land width. Detailed aspects of the prototype measurement system byilt for experiment are described, and test results are discussed. As conclusions, it is proved that the methods are effec- tive especially for-in situ application with a measuring accuracy of 0.01mm.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2008.10a
• /
• pp.1727-1734
• /
• 2008

After the final closure of sea dyke, seepage behaviour of embankment is highly changed by variation of water head different between tide wave and controlled water level at fresh lake. Especially, the seepage behaviour of bottom protection layer of final closure section is more important factor for structural and functional stability of sea dyke, because of the bottom protection layer of final closure section is penetrated sea side to fresh lake. Even though bottom protection layer was filled with dredged fine sand, it has a high permeability. In this paper, mainly described about the seepage velocity and borehole image of bottom protection layer filled with dredged sand after final closure. Various in-situ tests such as BIPS (Borehole Image Processing System) and ABI (Acoustic Borehole Imager) survey, wave velocity measuring, and color tracer survey were conducted to evaluate the seepage behavior of bottom protection layer. Based on the in-situ tests, the bottom protection layer of final closure section was almost filled with dredged sand which is slightly coarse grain sand and there have sea water flow by water head different between tide wave and controlled water level at fresh lake. Also, comply with tracer survey results, the sea water flow path was not exist or generated in the bottom protection layer. However, because of this result not only short term survey but also just one test borehole survey results, additional long term and other borehole tests are needed.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2009.11a
• /
• pp.64-64
• /
• 2009

As the advanced packaging technology developing, Copper electro-plating processing has be wildly utilized in the semiconductor interconnect technique. Chemical solution monitoring methods, including PH and gravity measurement exist in industry, but economical and practical real-time monitoring has not been achieved yet. Red-green-blue (RGB) color sensor can successfully monitor the condition of $CuSO_4$ solution during electric copper plating process. Comparing the intensity variations of the RGB data and optical spectroscopy data, strong correlation between two in-situ sensors have shown.