• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 추계학술대회
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• pp.917-920
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• 2014

우리나라는 1995년 이동전화 가입자수가 백만명, 1998년 천만명을 돌파하고 비약적으로 증가하여 현재 우리나라는 인구대비 이동통신단말기의 보급률이 110%를 넘어섰다. 현재는 어린이나 학생 등 비경제 활동 인구들까지 이동통신 단말기를 사용하고 있다. 명백히 필수재가 된 이동통신 단말기는 그 보급대수가 냉장고, 세탁기, 진공청소기, 승용차를 추월하고 있다. 그런데 이동통신의 생활화는 우리의 생활을 편리하게 하며 이동통신 단말기는 아주 중요한 필수재로 자리매김하였으나 단말기 대금을 비롯한 통신관련 비용은 가계의 큰 부담이 되고 있다. 그런데 공정한 경쟁을 통하여 소비자 후생 나아가 사회적 후생을 최대화 할 수 있도록 시장의 실패를 방지해야할 정부는 적시에 적절한 역할을 하지 못하고 있는 것으로 보인다. 이는 주인-대리인(principal-agent)관점에서도 이해될 수 있을 것이다. 이동통신전화가 상용화된 1990년대 초부터 현재까지의 이동통신정책중 이동통신망의 공동이용, 번호이동, 단말기 유통과 이통서비스의 분리, 망중립성 확보는 주인-대리인문제와 관련한 문제점들을 노정하고 있다.

• 한국정보통신학회논문지
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• 제23권11호
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• pp.1351-1356
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• 2019

본 연구는 빅데이터 플랫폼을 이용해 만성질환자에 따른 개인적 요인과 지역사회요인이 삶의 질에 미치는 영향을 알아보는데 목적이 있다. 연구방법은 2017년 지역사회건강조사 자료와 통계청 시군구별 2차 자료를 사용하였고, EQ-5D 지수와 개인요인 및 지역사회요인을 구분하여 다수준분석을 실시하였다. 연구결과 남자의 경우, 나이가 어릴수록, 학력이 높을수록, 월가구소득이 많을수록, 경제활동을 하는 경우, 스포츠 인프라가 많은 경우 삶의 질이 높았다. 또한 주관적 건강감이 나쁠수록, 스트레스가 많을수록 삶의 질이 낮았다. 향후 의료 빅데이터 분석을 위해 클라우드와 오픈소스를 활용할 수 있는 하드웨어에 독립적인 플랫폼 제공을 위한 연구가 지속되어야 할 것이다.

• 토지주택연구
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• 제14권1호
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• pp.1-16
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• 2023

본 연구에서는 한국고용정보원의 청년패널조사(YP2007) 10-14차(2016~2020년) 직업력 자료를 이용하여 미혼 청년층의 주거 관련 특성 현황들을 살펴보고, 주거의 특성들과 취업한 일자리의 특성들이 결혼 의향(의지)에 미치는 영향을 실증적으로 분석하였다. 분석 결과를 종합해 보면, 고학력층, 고임금 취업자, 가구주이거나 경제적으로 독립한 청년층, 경제적으로 재정상태가 좋은 청년층은 결혼 의지가 높게 나타나고 있어 경제적 여건이 매우 중요한 요인으로 작용하고 있다. 결과적으로 부모로부터 경제적으로 독립한 상당수의 청년취업자 중에서도 상용직, 대기업, 고임금의 청년층은 결혼할 의향이 높게 나타나고 있는 반면, 임시/일용직, 중소기업, 저임금의 고용상태가 취약한 청년층은 결혼에 대한 의향도 낮게 나타나고 있다. 결국 노동시장에서 취약한 상태에 있는 청년층의 경우도 자신의 생애과정에 있어 매우 중요한 의미를 가지고 있는 결혼에 대해서도 포기하거나 미루게 되는 현상이 나타나고 있는 것으로 추정된다. 이에 청년층의 일자리 문제에 대한 개선과 지원정책을 강화함과 동시에 주거문제의 개선 및 대책도 충분히 검토되어야 한다.

• 대한화장품학회지
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• 제17권1호
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• pp.64-80
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• 1991

The SKINTEX Method is based on a two-compartment physico-chemical model which includes a Biomembrane Barrier in compartment one and an organized macromolecular matrix in compartment two. Test samples absorb onto or permeate through the keratin/collagen Biomembrane Barrier and then can interact with the organized macromolecular matrix. Changes in the integrity of the barrier release a dye indicator: Changes in the matrix can alter its transparency. The sum of these two responses is read spectrophotometrically at 470nm. An early investigation of 950 chemicals and formulations in the SKINTEX System produced results which were 89% concordance to in vivo Draize dermal irritation results obtained with 24-hour occluded application of test samples with-out abrasion and standard scoring. Alkaline materials were analyzed in a specialized SKINTEX AMA Protocol. In this early study, the model did not distinguish nonirritant test materials and formulation with PDII(Primary Dermal Irritation Index)in the range from 0 to 1.2, A High Sensitivity Assay Protocol(HSA)was developed to amplify the changes in both compartments of this model and provide more accurate calibration of these changes. A study of 60 low irritation test samples including cosmetics, household products, chemicals and petro-chemicals distinguished nonirritants with PDII $\leq$ 0.7 for 26 of 30 nonirritants. A second protocol was developed to evaluate the SKINTEX model predictability with respect to human irritation. The Human Response Assay (HRA )has been optimized based on differences in penetration and irritation responses in humans and rabbits. An additional 32 test materials with different mechanisms and degrees of dermal toxicity were evaluated by the HRA. These in vitro results were 86% concordant to human patch test results. In order to further evaluate this model, a Standard Chemical Labelling (SCL) Protocol was developed to optimize this system to predict Draize dermal irritation results after a 4-hour application of the test material. In a study of 52 chemicals including acids, bases, solvents, salts, surfactants and preservatives, the SCL results demonstrated 85% concordance to Draize results for a 4-hour application of test samples on non-abraded rabbit skin. The SKINTEX System, including three specialized protocols, provided results which demonstrated good correlation to the endpoint of dermal irritation in man and rabbits at different application times.

• 대한의생명과학회지
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• 제29권4호
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• pp.274-279
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• 2023

In this study, we use data from the 2021 National Health and Nutrition Examination Survey to determine the relationship between oral health and depression in Korean adults and provide basic data to prevent oral diseases that affect depression. The final subjects of the study were 5,952 adults aged 19 or older among the 7,090 subjects who responded to the survey in the 3rd year of the 8th period (2021), and the total frequency discrepancy in the research results was omitted due to missing values. Complex sample logistic regression analysis was performed to confirm the relationship between oral health and depression. Depression according to general characteristics depends on gender (P < 0.001), number of household members (P = 0.047), and subjective health level (P < 0.001). Depression according to oral characteristics was statistically significant for complaints of chewing discomfort (P = 0.006) and toothache within the past year (P = 0.023). As a result of analyzing factors affecting depression, in terms of gender, men are 0.43 times more likely than women (95% CI: 0.28~0.65), and in terms of subjective health level, good compared to bad is 0.46 times more likely (95% CI: 0.28~0.75), the average was 0.59 times (95% CI: 0.40~0.87) higher, which was statistically significant. Therefore it seems necessary to improve mental health such as depression in order to relieve oral discomfort and to motive people to take responsibility for won health through oral health education programs related to oral health to oral health related to oral health and mental health.

• Clinical and Experimental Vaccine Research
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• 제12권2호
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• pp.97-106
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• 2023

Purpose: Rabies is a fatal but preventable disease with proper pre-exposure anti-rabies vaccination (ARV). Dogs, as household pets and strays, are the reservoir and vector of the disease, and dog bites have been associated with human rabies cases in Sri Lanka over the past few years. However, other susceptible species having frequent contact with humans may be a source of infection. One such species is sheep and immunity following ARV has never been tested in sheep reared in Sri Lanka. Materials and Methods: We have tested serum samples from sheep reared in the Animal Centre, Medical Research Institute of Sri Lanka for the presence of anti-rabies antibodies following ARV. Sheep serum samples were tested with Bio-Pro Rabies enzyme-linked immunosorbent assay (ELISA) antibody kits used for the first time in Sri Lanka and our results were verified by a seroneutralization method on cells (fluorescent antibody virus neutralization, FAVN test) currently recommended by World Organization for Animal Health and World Health Organization. Results: Sheep received annual ARV and maintained high neutralizing antibody titers in their serum. No maternal antibodies were detected in lamb around 6 months of age. Agreement between the ELISA and FAVN test, i.e., coefficient concordance was 83.87%. Conclusion: Annual vaccination in sheep has an effect on maintaining adequate protection against rabies by measurements of anti-rabies antibody response. Lambs need to be vaccinated earlier than 6 months of age to achieve protective levels of neutralizing antibodies in their serum. Introducing this ELISA in Sri Lanka will be a good opportunity to determine the level of anti-rabies antibodies in animal serum samples.

• Journal of Microbiology and Biotechnology
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• 제10권3호
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• pp.349-354
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• 2000

Abstract A facultative alkalophilic gram-negative Vibrio metschnikovii strain RH530, isolated from the wastewater, produced several alkaline proteases (VAP) including six alkaline serine proteases and a metalloprotease. From this strain, high yielding YAP mutants were isolated by NTG treatment. The isolated mutant KS1 showed nine times more activity than the wild-type after optimization of the culture media. The production was regulated by catabolite repression when glucose was added to the medium. The effects of several organic nitrogen sources on the production of the YAP were investigated to avoid catabolite repression. The combination of 4% wheat gluten meal (WGM), 1.5% cotton seed flour (eSF), and 5% soybean meal (SBM) resulted in the best production when supplemented with 1% NaCl. The YAP showed a resistance to surfactants such as $sodium-{\alpha}-olefin$ sulfonate (AOS), polyoxy ethylene oxide (POE), and sodium dodecyl sulfate (SDS), yet not to linear alkylbenzene sulfonate (LAS). However, the activity of the YAP was restored completely when incubated with LAS in the presence of POE or $Na_2SO_4$. The YAP was stable in a liquid laundry detergent containing 6.6% SLES (sodium lauryl ether sulfate), 6.6% LAS, 19.8% POE, and stabilizing agents for more than two weeks at $40^{\circ}C$, but the stability was sharply decreased even after 1 day when incubated at $60^{\circ}C$. A washing performance test with the YAP exhibited it to be a good washing power by showing 51 % and 60% activity at $25^{\circ}C{\;}and{\;}40^{\circ}C$, respectively, thereby indicating that the YAP also has a good detergency at a low temperature. All the results suggest that the YAP produced from the mutant strain KSI has suitable properties for use in laundry detergents.rgents.

• 한국콘텐츠학회논문지
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• 제20권4호
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• pp.244-253
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• 2020

본 연구는 2017년도 지역사회건강조사 자료를 이용하여 65세 이상 남성노인과 여성노인의 인구사회학적 특성, 건강행태 및 주관적 건강수준, 의료이용 등에 따른 행복감 수준과 행복감에 영향을 미치는 요인을 평가해 보고자 하였다. 연구대상은 남성노인 27,979명, 여성노인 39,856명으로 총 67,835명으로 선정하였다. 연구결과 여성노인은 남성노인보다 교육수준과 가구 총 소득이 행복감에 영향을 주었고 남성노인은 배우자 유무가 행복감에 영향을 주어 배우자가 있는 경우 행복감 수준이 높았다. 그리고 남성노인과 여성노인 모두 건강행태 및 주관적 건강수준이 좋을 때 의료이용에 제한이 없을 때 행복감을 크게 느꼈다. 이는 노년기에는 신체 생리적인 기능의 감퇴로 인하여 다른 연령집단에 비해 신체적 건강에 대한 취약성이 증가하는 시기이므로 건강행태 및 주관적 건강수준, 의료이용이 큰 영향을 미치는 것으로 생각된다. 이러한 결과를 토대로 국가적 차원에서 노인복지를 위한 제정을 확대하여 노인의 성별 특성에 맞는 평생교육의 기회를 제공해야 하며 현재 운영되고 있는 노인교육, 건강관련기관의 프로그램을 노인의 특성에 맞게 운영되어야 할 것이다. 또한 노인과 관련된 사회서비스 체계 및 프로그램의 재평가 해 노년의 행복감을 좀 더 효과적으로 증진시킬 수 있는 서비스와 프로그램 개발을 위한 노력이 필요하다.

• 농촌계획
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• 제6권1호
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• pp.19-28
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• 2000

Now in order to overcome the weakest points of the rural areas of the city of Kimje and, transform them into rural cultural villages which have local governing systems suitable to new localization age and activate this plan, we selected Daesan Village as a model village which had shown a lot of potentials in the basic research and studied it dividing it into the former part and the latter part. We studied Daesan village in the former part focusing on state analysis and basic ideas and in the latter part focusing on master plan and detail planning. We can summarize the conclusion like the followings. 1. Daesan Village located 8 kilometer away from the downtown Kimje and the city of Iksan respectably has comparatively good environment of good sunny place as an open field whose surrounding configuration of the ground consists of farming lands and low hills in front and rear. It has 38 farming households in all. 2. Human environment(인문환경); the village road whose width is about 4 meters is forming a flow system forking off into three. There is a route bus which operates three times a day even into the inside of the village. The main sources of revenue are vegetables in facilities, fruits and floriculture. Their average revenue is about 10.5 million won. 3. Here in DaeSan Village a legend dealing with Teasan literally meaning a big mountain consist of th village's tradition and you can see the tombs of a very faithful son and Anwi an army general in the age of the Japanese Invasion of Korea of 1592 to 1598 inside the village. 4. 85 out of the eitire population 141 whose age are over 20 showed very positive attitudes in a questionnaire about, making the village a cultural one and its development. 5. The basic of planned ideas is to increase the revenue of the farming household by making the village a professional farming one which has a state-of the-art production facility and agricultural technique. It is to make the village the one where people can enjoy the sense of the rural life and the farmer can enjoy their lives through consumptive and consistant leisure and resting activities. 6. We are planning to make entrance space, life space, rest and sport space, and cultural space considering the characteristics of the village and the demand of the resident. We are also planning to make tile entire city of Kimje an information transmitting base in short and long term perspectives. 7. DaeSan Village was planned as a place where tradition and the future exist together. On the basis of this concept we planned future programs for Daesan Village and in the latter part of the study master plans and detail plans will be continued.the regional agricultural condition. The development permissions were only during the period of restricted to use ($1979.12{\sim}1993.11$). We propose that the authority of development permission should be given to the local autonomy government, because the local government has the knowledge of its individual agricultural conditions.

• 한국환경농학회지
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• 제36권4호
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• pp.293-298
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• 2017

BACKGROUND: Pyrethroids (PYRs) are a widely used insecticide in agriculture and household area. In mammals, PYRs such as deltamethrin is metabolized to 3-phenoxybenzoic acid (3-PBA) in liver that is mainly excreted in urine. This study is designed to single exposure of deltamethrin to rats in a dose-dependent manner and identify the correlation between deltamethrin exposure and its metabolite (3-PBA) in urine. METHODS AND RESULTS: Exposure levels of deltamethrin were control (0 mg/kg bw), low (0.0705 mg/kg bw), medium (0.705 mg/kg bw) and high (7.05 mg/kg bw) dose. Low concentration was derived by ussing Korea predictive operator exposure model (KoPOEM). Dermal exposure persisted for 6 h, and urine specimens were collected for 24 h. The urine matrix was removed after a series of procedures and 3-PBA was analyzed by gas chromatography/mass spectrometry. CONCLUSION: There was a strong correlation ($R^2=0.83$) between the amount of oral exposure to delta me thrin and urinary levelof3-PBAexcreted. In dermal exposure groups of deltamethrin except high-dose, also there was a good correlation between urinary 3-PBA and deltamethrin exposure, but not stronger than in oral deltamethrin exposure groups. Based on these results, therefore, the amount of 3-PBA in urine can be used as a good monitoring indicator that reflexing the exposure level of deltamethrin to human body.