• Conservation and Restoration of Cultural Heritage
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• v.1 no.1
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• pp.29-37
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• 2012

The West Stone Pagoda at Gameunsaji Temple Site constructed in the 7th century is mainly composed of dark grey dacitic tuff bearing small numerous dioritic xenoliths. These xenoliths resulted in small holes due to differential weathering process from the host rocks. Physical strength of the pagoda was decreased due to weathering and damage caused by petrological, biological and coastal environmental factors. The southeastern part of the pagoda was extremely deteriorated that the rock surface showed exfoliation, fracture, open cavity, granular decomposition of minerals and salt crystallization by seawater spray from the eastern coast. The stone blocks were intersected by numerous cracks and contaminated by subsequent material such as cement mortar and iron plates. Also, the pagoda was colonized by algae, fungi, lichen and bryophytes on the roof rock surface and the gaps between the blocks. As a result of ultrasonic test, the rock materials fell under Highly Weathered Grade (HW) or Completely Weathered Grade (CW). Thus, conservational intervention is essentially required to prevent further weakening of the rock materials.

• The Journal of the Convergence on Culture Technology
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• v.4 no.2
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• pp.75-80
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• 2018

Since the introduction of the Foreign Patient Assistance Law in 2009, more than 300,000 foreign patients are visiting Korea each year due to the efforts of overseas patient attraction organizations, host companies and governments. Despite these achievements, however, the company is confronted with limitations in product development and the rate of patient population growth is slowing. Therefore, this study suggests the importance and meaning of various product development through the hierarchical analysis (AHP) on the major factors of product development of medical tourism services, and suggests direction of product development in domestic medical tourism industry in the future.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.22 no.1
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• pp.112-118
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• 2013

Formula race car is generally recognized as a vehicle which is optimally designed for on-road race track with the regulations of race host bodies. Especially, the uprights of suspension system decisively have effects on the performance of cornering and stability of race car's driving performance, which are very important factors in the design of race car. This paper is a study of optimal upright design of F1800 grade formula race car which are normally used in professional race circuit in Korea. To design optimally the front upright of F1800 formula race car, Taguchi's orthogonal array, which is known for more useful method than full factorial design experimental method in cost and time, is used with CAE method such as FEM analysis. And the result of this paper shows that Taguchi's orthogonal array employed for this optimal design is very useful for designing the front upright of race car by minimizing its weight as well as keeping its safety factor as enough as designer wants in the view of quality, cost and delivery at the early design step.

• International Journal of Industrial Entomology and Biomaterials
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• v.13 no.1
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• pp.37-43
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• 2006

Enterococcus faecalis was isolated from the body fluid of dead Galleria mellonella larvae. Upon injection of E. faecalis into the hemocoel of G. mellonella, the bacteria destroyed parts of humoral defense systems in the hemolymph. In a test for the proteolytic activity of E. faecalis CS, it was confirmed that the enzyme degraded three well-known a-helical antimicrobial peptides, cecropin A, melittin and halocidin, and abolished their activities. We also determined putative cleavage sites on the primary sequences of three peptides through purification and mass analysis of peptide fragments digested by E. faecalis CS. Furthermore it was found that apolipophorin-III, recently known as a critical recognition protein for invading microbes in the hemolymph of G. mellonella, was also degraded by E. faecalis CS. Taken together, the present work shows that the protease in secretions from E. faecalis destroyed two critical humoral immune factors in the hemolymph of G. mellonella larvae. In addition, this paper demonstrates that the relationship between the host insect and the pathogenic bacteria might provide a valuable model system to study the enterococcal virulence mechanism, which may be relevant to mammalian pathogenesis.

• Journal of Ocean Engineering and Technology
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• v.25 no.4
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• pp.59-65
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• 2011

In structural health monitoring (SHM) using electro-mechanical impedance signatures, it is a critical issue for extremely large structures to extract the best damage diagnosis results, while minimizing unknown environmental effects, including temperature, humidity, and acoustic vibration. If the impedance signatures fluctuate because of these factors, these fluctuations should be eliminated because they might hide the characteristics of the host structural damages. This paper presents a long-term SHM technique under an unknown noisy environment for tidal current power plant structures. The obtained impedance signatures contained significant variations during the measurements, especially in the audio frequency range. To eliminate these variations, a continuous principal component analysis was applied, and the results were compared with the conventional approach using the RMSD (Root Mean Square Deviation) and CC (Cross-correlation Coefficient) damage indices. Finally, it was found that this approach could be effectively used for long-term SHM in noisy environments.

• Clinical and Experimental Pediatrics
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• v.50 no.12
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• pp.1165-1172
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• 2007

Self/non-self discrimination and unresponsiveness to self is the fundamental properties of the immune system. Self-tolerance is a state in which the individual is incapable of developing an immune response to an individual's own antigens and it underlies the ability to remain tolerant of individual's own tissue components. Several mechanisms have been postulated to explain the tolerant state. They can be broadly classified into two groups: central tolerance and peripheral tolerance. Several mechanisms exist, some of which are shared between T cells and B cells. In central tolerance, the recognition of self-antigen by lymphocytes in bone marrow or thymus during development is required, resulting in receptor editing (revision), clonal deletion, anergy or generation of regulatory T cells. Not all self-reactive B or T cells are centrally purged from the repertoire. Additional mechanisms of peripheral tolerance are required, such as anergy, suppression, deletion or clonal ignorance. Tolerance is antigen specific. Generating and maintaining the self-tolerance for T cells and B cells are complex. Failure of self-tolerance results in immune responses against self-antigens. Such reactions are called autoimmunity and may give rise to autoimmune diseases. Development of autoimmune disease is affected by properties of the genes of the individual and the environment, both infectious and non-infectious. The host's genes affect its susceptibility to autoimmunity and the environmental factors promote the activation of self-reactive lymphocytes, developing the autoimmunity. The changes in participating antigens (epitope spreading), cells, cytokines or other inflammatory mediators contribute to the progress from initial activation to a chronic state of autoimmune diseases.

• Journal of Korean Society of Rural Planning
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• v.12 no.2 s.31
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• pp.37-47
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• 2006

Recently, due to the growing concern of the public in rural amenities and hobby farming works, much more urbanites, especially near-retirees, have been interested in rural life style than before. However, in spite of popular preference to ruralities, little has been known about their demand on retired rural life. Therefore, this study examined urbanites' attitude to preparatory works for out-migration, preferred residential site conditions and life style in the countryside. For this purpose, data were collected from a survey with the sample of 386 urban residents aged 40 to 65 rho hoped moving into the countryside after retirement, through structured questionnaires. Descriptive statistical works were performed using SPSS/PC windows program. The major findings of this study were as follows; (1) Host of urbanites, who answered in this study, planned to prepare ex-urban movement in their fifties and to put into practice in their sixties. (2) Key factors of location decision on movement were proximity/accessibility to centre city, medical service level, and distance to their family or friends. And about a half of respondents wanted second home in the countryside. (3) Most favoured rural life styles were nature-friendly well-being and hobby/healthy firming. Generally, the respondents of this survey had the positive attitude to do works in their later life, especially preferred to farming and volunteering in their communities.

• Journal of the Korean Society of Systems Engineering
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• v.7 no.1
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• pp.1-7
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• 2011

This work describes a study on the Analysis of Alternatives (AoA) based defense decision making. Future battle-space is transformed into a System of Systems (SoS) concept which is accomplished missions and their functions through network based battle management systems under forming their grids of various sensors and shooters in a single theater. The acquisition process is, therefore, changing over from single system requirements to capabilities based acquisition of SoS. AoA help to justify the need for starting, stopping, or continuing an acquisition program. AoA identify potentially viable solutions and provide comparative cost, effectiveness, and risk assessments of each solution to a baseline. The decision making must consider not only cost-effectiveness, risk, and military worth, but also domestic policy, foreign policy, technological maturity of the solution, the environment, the budget, treaties, and a host of additional factors. In this point of view, this paper analyzes AoA template which are critical elements of the defense decision making. From results of this analysis of AoA template for Korean acquisition environment are presented.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.120-120
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• 2018

Intestinal microbiota is strongly connected to health of host. It has been reported that not only metabolic disease like diabetes and obesity, but psychological diseases are affected by composition of intestinal microbiota. To figure it out the importance of the composition and relationship between disease and microbiota, intensive researches have done with human and experimental animals. But, the composition of the intestinal microbiota could be affected by several factors such as experimental environments, feeding, water, and bedding. As a result, the data from each experimental group might be diverse. It also affects experiments about biological activities of plant materials. In this study, mouse intestinal bacteria were isolated from fresh feces and identified by 16S rRNA gene to use in biological activities of natural medicines. The fecal supernatant was anaerobically incubated at $37^{\circ}C$ for 48 hours. Colonies were picked up separately and incubated again in same condition to increase quantity to analyze and stock. The bacteria strains were listed up and could be used for many researches including biological activities of plant materials and change in composition of intestinal bacteria itself.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.38 no.4
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• pp.195-203
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• 2012

Dental implants using titanium have greatly advanced through the improvement of designs and surface treatments. Nonetheless, the anatomical limits and physiological changes of the patient are still regarded as obstacles in increasing the success rate of implants further, even with the enhancement of implant products. So there have been many efforts to overcome these limits. The intrinsic potential for bone regeneration can be stimulated through adjuvant treatments with the continuous improvement of implant properties, and this can play an important role in achieving optimum osseointegration toward peripheral bone tissue and securing ultimate long-term implant stability in standard surgical procedures. For this purpose, various chemical, biological, or biophysical measures were developed such as bone grafts, materials, pharmacological agents, growth factors, and bone formation proteins. The biophysical stimulation of bone union includes non-invasive and safe methods. In the beginning, it was developed as a method to enhance the healing of fractures, but later evolved into Pulsed Electromagnetic Field, Low-Intensity Pulsed Ultrasound, and Low-Level Laser Therapy. Their beneficial effects were confirmed in many studies. This study sought to examine bone-implant union and its latest trend as well as the biophysical stimulation method to enhance the union. In particular, this study suggested the enhancement of the function of cells and tissues under a disadvantageous bone metabolism environment through such adjunctive stimulation. This study is expected to serve as a treatment guideline for implant-bone union under unfavorable circumstances caused by systemic diseases hampering bone metabolism or the host environment.