• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.19 no.3
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• pp.327-364
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• 2015

In this paper, a generalized guidance law with an arbitrary pair of guidance coefficients for impact angle control is proposed. Under the assumptions of a stationary target and a lag-free missile with constant speed, necessary conditions for the guidance coefficients to satisfy the required terminal constraints are obtained by deriving an explicit closed-form solution. Moreover, optimality of the generalized impact-angle control guidance law is discussed. By solving an inverse optimal control problem for the guidance law, it is found that the generalized guidance law can minimize a certain quadratic performance index. Finally, analytic solutions of the generalized guidance law for a first-order lag system are investigated. By solving a third-order linear time-varying ordinary differential equation, the blowing-up phenomenon of the guidance loop as the missile approaches the target is mathematically proved. Moreover, it is found that terminal misses due to the system lag are expressed in terms of the guidance coefficients, homing geometry, and the ratio of time-to-go to system time constant.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.485-487
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• 2009

최근 무선 멀티 인터페이스를 이용한 동시 접속 기술에 관한 연구가 활발히 진행 중이다. 이와 관련된 연구로 IETF Netext WG에서 Proxy Mobile IPv6 (PMIPv6) 기반 멀티인터페이스 지원 기술에 대해서 표준 기술이 논의 중에 있으며 IETF MIF(Multiple InterFace) WG에서도 멀티인터페이스 노드 관점와 네트워크 관점에서 멀티 네트워크 인터페이스 지원 시 발생하는 문제점을 정의하고 이를 해결하기 위한 기존 기술 분석을 진행 중이다. 본 논문에서는 Proxy MIPv6 도메인에서 멀티 호밍 지원 기술을 가진 Proxy MIPv6 프로토콜을 이용한 멀티인터페이스 동시접속과 인터페이스 사이의 inter handoff 지원 기술 시 발생하는 문제점들을 정의하고 가능한 해결 시나리오에 대해서 논의한다.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.68 no.4
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• pp.566-572
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• 2019

This paper proposes a new composite guidance law that can intercept moving targets and satisfy look angle rate constraint. In order to obtain the composite guidance law, we first develop a new look angle rate control guidance law which can maintain the maximum look angle rate limitation. And then, we propose the composite guidance scheme on the basis of the look angle rate control guidance and the proportional navigation guidance. To investigate the capturablity and characteristics of the proposed guidance, we also derive closed-form solutions and perform various numerical simulations. The proposed composite guidance only requires the line-of-sight rate, closing velocity, and missile's speed, thereby easily implementing in practical homing missiles.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• v.3 no.4
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• pp.199-203
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• 2022

The spring home range and habitat use of the spot-billed duck in Korea were studied using GPS-mobile phone-based telemetry (WT-300). The study areas were Anseong-si, Seosan-si, Nonsan-si, and Sejong-si. Analysis was performed using minimum convex polygon (MCP) and kernel density estimation (KDE) spot-billed ducks had an average home range of 70.28 km² (standard deviation [SD]=84.50, n=6), and a core habitat (50%) 2.66 km² (SD=2.60, n=6), according to MCP and KDE, respectively. Wetlands (41.5%) and rice fields (35.7%) were highly used as habitats. The rice field use rate was high during the day, and the wetland utilization rate was high at night. Rice fields and wetlands were the primary habitats in spring.

• International Journal of Advanced Culture Technology
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• v.11 no.3
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• pp.89-93
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• 2023

This study is a case study of the Ukrainian military's asymmetric combat performance method. The composition of this study is as follows. First, it presented the background for the outbreak of war in the macroscopic framework of Russia-Ukraine. Second, the Ukraine-Russia war, which broke out in February 2022, presented the justification for the study, that is, the direction of the Ukrainian military's asymmetric combat performance in terms of microscopic aspects of the study, and detailed analysis of precision strikes using commercial drones and advanced sensors. Finally, we covered in-depth the case of Ukrainian troops who attempted to attack Russian tanks using semi-automatic laser homing technology. Therefore, the Korean military organization also suggested the justification for gradually introducing and utilizing the system for the Ukrainian military's asymmetric combat performance method, and related follow-up studies should be actively conducted following this study.

• BMB Reports
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• v.56 no.2
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• pp.71-77
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• 2023

Cancers are one of the most dreaded diseases in human history and have been targeted by numerous trials including surgery, chemotherapy, radiation therapy, and anti-cancer drugs. Adult stem cells (ASCs), which can regenerate tissues and repair damage, have emerged as leading therapeutic candidates due to their homing ability toward tumor foci. Stem cells can precisely target malicious tumors, thereby minimizing the toxicity of normal cells and unfavorable side effects. ASCs, such as mesenchymal stem cells (MSCs), neural stem cells (NSCs), and hematopoietic stem cells (HSCs), are powerful tools for delivering therapeutic agents to various primary and metastatic cancers. Engineered ASCs act as a bridge between the tumor sites and tumoricidal reagents, producing therapeutic substances such as exosomes, viruses, and anti-cancer proteins encoded by several suicide genes. This review focuses on various anti-cancer therapies implemented via ASCs and summarizes the recent treatment progress and shortcomings.

• IMMUNE NETWORK
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• v.20 no.3
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• pp.20.1-20.15
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• 2020

Memory CD8+ T cells in the immune system are responsible for the removal of external Ags for a long period of time to protect against re-infection. Naïve to memory CD8+ T cell differentiation and memory CD8+ T cell maintenance require many different factors including local environmental factors. Thus, it has been suggested that the migration of memory CD8+ T cells into specific microenvironments alters their longevity and functions. In this review, we have summarized the subsets of memory CD8+ T cells based on their migratory capacities and described the niche hypothesis for their survival. In addition, the basic roles of CCR7 in conjunction with the migration of memory CD8+ T cells and recent understandings of their survival niches have been introduced. Finally, the applications of altering CCR7 signaling have been discussed.

• 대한공업교육학회지
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• v.33 no.2
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• pp.287-299
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• 2008

HTTP is one of the most widely used protocols of the WWW. Currently it uses TCP as the transport layer protocol to provide reliability. The HTTP uses separate TCP connection for each file request and adds unnecessary head-of-line blocking overhead for the file retrieval. The web application is short sized and affected by the increased handover latency of TCP in wireless environment. SCTP has attractive features such as multi-streaming and multi-homing. SCTP's multi-streaming and multi-homing avoid head-of-line blocking problem of TCP and reduce handover latency of TCP in wired and wireless environment. Mean response time is the important measure in most web application. In this paper, we present the comparison of mean response time between HTTP over SCTP with that of HTTP over TCP in wired and wireless environments using NS-2 simulator. We measured mean response time for varying packet loss rate, bandwidth, RTT, and the number of web objects in wired environment and mean response time and packet loss rate for varying moving speed and region size in wireless environment. Our experimental result shows that SCTP reduces the mean response time of TCP based web traffic.

• Explosives and Blasting
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• v.22 no.3
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• pp.79-84
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• 2004

It is well accepted that modem emulsion explosives are intrinsically much less sensitive than traditional products such as dynamites or black powder. However, they have still been involved in a significant number of accidental explosions. In October 1975, Canadian Research, Limited's, Energetic Research Laboratory in Quebec exploded. Although explanations for the incident varied, one logical explanation was that the pump used in transporting the emulsion dead headed, thereby turning mechanical work in to frictional heating under a zero flow rate. There is a minimum pressure required for combustion(MBP) to propagate in emulsion explosives. A stable deflagration may lead to a deflagration-to-detonation transition(DDT) in emulsion explosives. Tests were also performed on sensitized sampled consisting of 6 to 21% waters as well as 1 to 11% aluminium powder. It was founded the emulsion explosives consisting of 6% waters had the lowest minimum homing pressure(MBP) of 3 bar, and the 21% waters were unable to achieve sustained homing at pressures as high as 100 bar. The aluminium contained explosives tested here displayed a MBP higher than that of without emulsion. It appears that this test may offer a firm ground for the classification of emulsion explosives in view of the regulating the hazards associated with the various process used for their manufacturing and transport.

• Journal of Life Science
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• v.26 no.9
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• pp.1027-1032
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• 2016

Antigen is substance causing disease derived from pathogen. Living organism has the immune system in terms of defense mechanism against antigen. Antigen is processed through several pathways such as phagocytosis, antibody action, complement activation, and cytotoxins by NK or cytotoxic T lymphocyte via MHC molecule. Lymph node (LN) is comprised of the complicated 3 dimensional network and several stromal cells. Fibroblastic reticular cells (FRC) are distributed in T zone for interaction with T cells. FRC produces the extra cellular matrix (ECM) into LN for ECM reorganization against pathogen infections and secretes homing chemokines. However, it has not so much been known about the involvement of the antigen process of FRC. The present report is for the function of FRC on antigen process. For this, FRC was positioned with several infected situations such as co-culture with macrophage, T cell, lipopolysaccharide (LPS) and TNFα stimulation. When co-culture between FRC with macrophage and T cells was performed, morphological change of FRC was observed and empty space between FRCs was made by morphological change. The matrix metallo-proteinase (MMP) activity was up-regulated by Y27632 and T cells onto FRC. Furthermore, inflammatory cytokine, TNFα regulated the expression of adhesion molecules and MHC I antigen transporter in FRC by gene chip assay. NO production was elevated by FRC monolayer co-cultured with macrophage stimulated by LPS. GFP antigen was up-taken by macrophage co-cultured with FRC. Collectively, it suggests that FRC assists of the facilitation of antigen process and LN stroma is implicated into antigen process pathway.