• Genomics & Informatics
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• v.11 no.1
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• pp.55-57
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• 2013

Growing numbers of studies employ cell line-based systematic short interfering RNA (siRNA) screens to study gene functions and to identify drug targets. As multiple sources of variations that are unique to siRNA screens exist, there is a growing demand for a computational tool that generates normalized values and standardized scores. However, only a few tools have been available so far with limited usability. Here, we present siMacro, a fast and easy-to-use Microsoft Office Excel-based tool with a graphic user interface, designed to process single-condition or two-condition synthetic screen datasets. siMacro normalizes position and batch effects, censors outlier samples, and calculates Z-scores and robust Z-scores, with a spreadsheet output of >120,000 samples in under 1 minute.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.1539-1543
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• 2006

We have developed self-aligned imprint lithography (SAIL) technology, an innovative method for roll-to-roll (R2R) fabrication of electronic devices on flexible plastic substrates. In this paper, we present the first R2R-produced ${\alpha}$-Si TFTs built on a polyimide substrate using the SAIL process, and prove the feasibility of this technology to enable R2R fabrication of flexible display active matrix (AM) backplanes with high precision and throughput.

• Journal of the Korean Ceramic Society
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• v.45 no.10
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• pp.605-609
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• 2008

This work describes the preparation of functionalized magnetic nanoparticles(MNPs) and their bioapplication to human DNA separation. Silica coated MNPs were prepared by changing the volume ratio of tetraethyl orthosilicate(TEOS) for controlled coating thickness on the original nanoparticle of MNPs. The sol-gel process in silica coating on MNPs surface was adapted for relatively mild reaction condition, low-cost, and surfactant-free. And then amino functionalized magnetic nanoparticles were synthesized using amine groups as surface modifiers. The result of adsorption efficiency for human DNA with amino-functionalized silica coated MNPs was calculated as a function of the number of amine groups.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.46.5-46
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• 2002

As device dimension shrinks down to sub 100nm, it is increasingly important to monitor plasma states. Plasma etching is a key means to fine patterning of thin films. Many parameters are involved in etching and each parameter has different impact on process performances, including etch rate and profile. The uniformity of etch responses should be maintained high to improve device yield and throughput. The uniformity can be measured on any etch response. The most difficulty arises when attempting to characterize etched profile. Conventionally, the profile has been estimated by measuring the slope or angle of etched pattern. One critical drawback in this measurement is that this is unable to cap...

• Proceedings of the IEEK Conference
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• 1999.11a
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• pp.368-371
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• 1999

In this paper, we propose a neural network processor architecture with on-chip learning and with reconfigurability according to the data dependencies of the algorithm applied. For the neural network model applied, the proposed architecture can be configured into either SIMD or SRA(Systolic Ring Array) without my changing of on-chip configuration so as to obtain a high throughput. However, changing of system configuration can be controlled by user program. To process activation function, which needs amount of cycles to get its value, we design it by using PWL(Piece-Wise Linear) function approximation method. This unit has only single latency and the processing ability of non-linear function such as sigmoid gaussian function etc. And we verified the processing mechanism with EBP(Error Back-Propagation) model.

• Journal of the Semiconductor & Display Technology
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• v.12 no.4
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• pp.15-20
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• 2013

Nanoimprint lithography (NIL) is the next generation photolithography process in which the photoresist is dispensed onto the substrate in its liquid form and then imprinted and cured into a desired pattern instead of using traditional optical system. There have been considerable attentions on NIL due to its potential abilities that enable cost-effective and high-throughput nanofabrication to the display device and semiconductor industry. In this paper, a pressure vessel type imprinting system was used to imprint patterns with two type pressure values (25 bar, 30 bar) and two type pressure keeping times (5 min, 10 min). The height of transferred pattern and the thickness of residual layer were measured and effects of pressurization conditions - pressure and pressure keeping time - on the pattern transfer in thermal NIL were investigated.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.5
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• pp.2362-2378
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• 2017

To mitigate the performance degradation caused by performance anomaly, a number of channel assignment algorithms have been proposed for multi-rate wireless mesh networks. However, network conditions have not been fully considered for routing process in these algorithms. In this paper, a joint scheme called Multi-rate Dijkstra's Shortest path - Rate Separated (MDSRS) is proposed, combining routing metrics and channel assignment algorithm. In MDSRS, the routing metric are determined through the synthesized deliberations of link costs and rate matches; then the rate separated channel assignment is operated based on the determined routing metric. In this way, the competitions between high and low rate links are avoided, and performance anomaly problem is settled, and the network capacity is efficiently improved. Theoretical analysis and NS-3 simulation results indicate that, the proposed MDSRS can significantly improve the network throughput, and decrease the average end-to-end delay as well as packet loss probability. Performance improvements could be achieved even in the heavy load network conditions.

• Molecules and Cells
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• v.22 no.3
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• pp.254-261
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• 2006

DNA microarray is a powerful tool for high-throughput analysis of biological systems. Various computational tools have been created to facilitate the analysis of the large volume of data produced in DNA microarray experiments. Normalization is a critical step for obtaining data that are reliable and usable for subsequent analysis such as identification of differentially expressed genes and clustering. A variety of normalization methods have been proposed over the past few years, but no methods are still perfect. Various assumptions are often taken in the process of normalization. Therefore, the knowledge of underlying assumption and principle of normalization would be helpful for the correct analysis of microarray data. We present a review of normalization techniques from single-labeled platforms such as the Affymetrix GeneChip array to dual-labeled platforms like spotted array focusing on their principles and assumptions.

• Journal of Information Display
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• v.12 no.2
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• pp.89-92
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• 2011

Advanced static DC magnetron sputtering methods based on the magnet wobbling technique were investigated to achieve highly uniform and homogeneous metallization layers. The novel split sputter mode (SSM) method, wherein the deposition process is divided into two distinct steps, enables the AKT rotary cathode technology to provide excellent layer properties, while keeping a high production throughput. The effectiveness of theSSMtechnique was demonstrated through copper-coated large-area substrates.

• Proceedings of the PSK Conference
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• 2003.10a
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• pp.97-99
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• 2003

With advances in determining the entire DNA sequence of the human genome, it is now critical to systematically identify the function of a number of genes in the human genome. These biological problems, especially those in human diseases including cancer, should be addressed in human cells in which genetic approaches have been extremely difficult to implement. To overcome this, my efforts have focused on the development of a novel “chemical genetic/genomic approach” that uses small molecules to “probe and identify” the function of genes in specific biological process or pathway in human cells. (omitted)