• Communications for Statistical Applications and Methods
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• v.15 no.3
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• pp.325-332
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• 2008

We consider estimation of reliability P(Y < X) and distribution of the ratio when X and Y are independent uniform random variable and power function random variable, respectively and also consider the estimation problem when X and Y are independent uniform random variable and a half-normal random variable, respectively.

• Journal of the Korean Data and Information Science Society
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• v.21 no.4
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• pp.757-764
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• 2010

In this paper, we develop the reference priors for the common location parameter in the half-normal distributions with unequal scale paramters. We derive the reference priors as noninformative prior and prove the propriety of joint posterior distribution under the general prior including the reference priors. Through the simulation study, we show that the proposed reference priors match the target coverage probabilities in a frequentist sense.

• Journal of the Korean Society of Radiology
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• v.9 no.5
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• pp.287-293
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• 2015

Because of esophageal cancer has the long length of the lesion and also inhomogeneous in depth. So, the radiation dose distribution was inhomogeneous in radiation therapy. To overcomes the dose distribution uniformity using half beam method. Patient's CT image was used radiation treatment planning. We used two planning methods that one is the using normal beam and another is using half beam. Than comparing the two radiotherapy planning using target coverage, dose volume histogram, conformity index, homogeneity index and normal tissues - heart, spinal cord, lung -. In results, Treatment planning using half beam is little more than normal beam in target coverage, dose volume histogram, conformity index, homogeneity index and normal tissues covering. However, If the patient is not correct position patients may arise a side effect. Thus, the using in Half beam involving the geometrically exact under lung cancer is considered to advantage.

• Journal of the Korean Data and Information Science Society
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• v.22 no.6
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• pp.1265-1273
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• 2011

This article deals with the problem of testing the equality of the location parameters in the half-normal distributions. We propose Bayesian hypothesis testing procedures for the equality of the location parameters under the noninformative prior. The non-informative prior is usually improper which yields a calibration problem that makes the Bayes factor to be defined up to arbitrary constants. This problem can be deal with the use of the fractional Bayes factor or intrinsic Bayes factor. So we propose the default Bayesian hypothesis testing procedures based on the fractional Bayes factor and the intrinsic Bayes factors under the reference priors. Simulation study and an example are provided.

• Korean Journal of Clinical Pharmacy
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• v.1 no.1
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• pp.31-36
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• 1991

Tobramycin is one of the most frequently selected agents for pharmacokinetic drug monitoring because of its narrow therapeutic index and essential role for the management of serious infections, especially gram-negative infections. Its pharmacokinetic parameters are dependent on race, sex, age, ideal body weight. disease states, and etc. Therefore, to schedule the dosing of tobramycin, the individual pharmacokinetic parameters such as half-life and volume of distribution are needed. However, these pharmacokinetic parameters have never been reported in Koreans. The purposes of this study were to evaluate the volume of distribution of tobramycin in cancer patients who had normal renal function, to compare the mean values of Vd reported in the literature, and to compare the measured half-life with the expected half-life based on ABW, LBW, and IBW, respectively. Venous blood samples were collected just before and thirty minutes after dosing during steady state. Serum tobramycin concentrations were determined by $TD_x$ (fluorescence immunoassay). IBW were measured by the method of Devine: and LBW were measured by the method of Hallynck. Creatinine clearances (CLcr) of the patients were estimated using the Cockcroft and Gault equation. Elimination rate constants (kel) were determined using the Welling and Craig equation. Infusion rate (ko), volume of distribution (Vd), and half-life $(t_{1/2})$ were determined using the Saw chuk and Zaske equation. The volume of distribution Was $27\%$ greater than the Schentag's study (0.26 vs 0.33 l/kg), but the half-life was similar to the Levy's study. The predicted half-lives based on IBW were the closest to actual half-lives (1.85 vs 2.01 hr).

• Communications for Statistical Applications and Methods
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• v.31 no.4
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• pp.409-425
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• 2024

Logistic regression models are commonly used to explain binary health outcome variable using independent variables such as patient characteristics in medical science and public health research. Although there is no distributional assumption required for independent variables in logistic regression, variables with severely right-skewed distribution such as lab values are often log-transformed to achieve symmetry or approximate normality. However, lab values often have zeros due to limit of detection which makes it impossible to apply log-transformation. Therefore, preprocessing to handle zeros in the observation before log-transformation is necessary. In this study, five methods that remove zeros (shift by 1, shift by half of the smallest nonzero, shift by square root of the smallest nonzero, replace zeros with half of the smallest nonzero, replace zeros with the square root of the smallest nonzero) are investigated in logistic regression setting. To evaluate performances of these methods, we performed a simulation study based on randomly generated data from log-normal distribution and logistic regression model. Shift by 1 method has the worst performance, and overall shift by half of the smallest nonzero method, replace zeros with half of the smallest nonzero method, and replace zeros with the square root of the smallest nonzero method showed comparable and stable performances.

• 한국전산유체공학회:학술대회논문집
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• 2004.10a
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• pp.151-154
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• 2004

The HANARO, a multi-purpose research reactor of 30 MWth open-tank-in-pool type, has been under normal operation since its initial criticality in February, 1995. Many experiments should be safely performed to activate the utilization of the HANARO. A flow simulated test facility has been developed for the verification of structural integrity of those experimental facilities prior to loading In the HANARO. This test facility is composed of three major parts; a half-core structure assembly, flow circulation system and support system. The half-core structure assembly is composed of plenum, grid plate, core channel with flow tubes, chimney and dummy pool. The flow channels are to be filled with flow orifices to simulate similar flow characteristics to the HANARO. This paper describes an analysis of the flow distribution of the cote channel and compares with the test results. As results, the analysis showed similar flow characteristics compared with those in the test results.

• The Korean Journal of Applied Statistics
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• v.26 no.1
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• pp.37-47
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• 2013

A Q-Q plot is an effective and convenient graphical method to assess a distributional assumption of data. The primary step in the construction of a Q-Q plot is to obtain a closed-form expression to represent the relation between observed quantiles and theoretical quantiles to be plotted in order that the points fall near the line y = a + bx. In this paper, we introduce a Q-Q plot to assess goodness-of-fit for inverse Gaussian distribution. The procedure is based on the distributional result that a transformed random variable $Y={\mid}\sqrt{\lambda}(X-{\mu})/{\mu}\sqrt{X}{\mid}$ follows a half-normal distribution with mean 0 and variance 1 when a random variable X has an inverse Gaussian distribution with location parameter ${\mu}$ and scale parameter ${\lambda}$. Simulations are performed to provide a guideline to interpret the pattern of points on the proposed inverse Gaussian Q-Q plot. An illustrative example is provided to show the usefulness of the inverse Gaussian Q-Q plot.

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.2
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• pp.141-146
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• 2010

This paper describes the static and dynamic characteristics of body mount system which are to be considered in the early design stage. At every location of body mount the static load and dynamic response to road input were calculated using the half car model. Normal mode analysis for the half car model was also performed. In the analysis the design parameters such as the stiffness of mount rubbers and their distribution on mount location were examined for improving ride comfort especially in the lower frequency range.

• Structural Engineering and Mechanics
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• v.54 no.5
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• pp.955-971
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• 2015

In this paper, the influence of the polled direction of piezoelectric materials on the stress distribution is studied under time-harmonic dynamical load (time-harmonic Lamb's problem). The system considered in this study consists of piezoelectric covering layer and piezoelectric half-plane, and the harmonic dynamical load acts on the free face of the covering layer. The investigations are carried out by utilizing the exact equations of motion and relations of the linear theory of electro-elasticity. The plane-strain state is considered. It is assumed that the perfect contact conditions between the covering layer and half-plane are satisfied. The boundary value problems under consideration are solved by employing Fourier exponential transformation techniques with respect to coordinates directed along the interface line. Numerical results on the influence of the polled direction of the piezoelectric materials such as PZT-5A, PZT-5H, PZT-4 and PZT-7A on the normal stresses, shear stresses and electric potential acting on the interface plane are presented and discussed. As a result of the analyses, it is established that the polled directions of the piezoelectric materials play an important role on the values of the studied stresses and electric potential.