Journal of the Korean Society of Radiology (한국방사선학회논문지)

The Korean Society of Radiology (한국방사선학회)
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The Usability Evaluation Half Beam Radiation Treatment Technique on the Esophageal Cancer

식도암 환자에서의 Half Beam 치료법의 유용성 평가

  • Park, Hochoon (Dept. of Radiation Oncology, Chunnam National University Hospital) ;
  • Kim, Youngjae (Dept. of Radiologic Technology, Daegu Health College) ;
  • Jang, Seongjoo (Dept. of Radiological Technology, Dongshin University)
  • 박호춘 (전남대학교병원 방사선종양학과) ;
  • 김영재 (대구보건대학교 방사선과) ;
  • 장성주 (동신대학교 방사선학과)
  • Received : 2015.06.04
  • Accepted : 2015.08.25
  • Published : 2015.06.30
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Abstract

Because of esophageal cancer has the long length of the lesion and also inhomogeneous in depth. So, the radiation dose distribution was inhomogeneous in radiation therapy. To overcomes the dose distribution uniformity using half beam method. Patient's CT image was used radiation treatment planning. We used two planning methods that one is the using normal beam and another is using half beam. Than comparing the two radiotherapy planning using target coverage, dose volume histogram, conformity index, homogeneity index and normal tissues - heart, spinal cord, lung -. In results, Treatment planning using half beam is little more than normal beam in target coverage, dose volume histogram, conformity index, homogeneity index and normal tissues covering. However, If the patient is not correct position patients may arise a side effect. Thus, the using in Half beam involving the geometrically exact under lung cancer is considered to advantage.

식도암은 병변의 길이가 길고 깊이의 불균질성으로 인하여 방사선의 균일한 선량분포를 얻기 어렵다. 이러한 문제점을 개선해 보고자 Half beam 법을 이용하여 선량분포의 균질성을 극복해 보고자 환자의 영상을 바탕으로 하여 Normal beam과 Half beam을 이용하여 각각 치료계획을 세워 표적체적포함율과 선량체적곡선, 일치성지수와 균질성지수를 상호 비교하고, 인접정상장기인 심장, 척수, 폐를 비교해 보고자 한다. 실험결과 Half beam을 이용한 치료계획이 표적체적포함율과 선량체적곡선 그리고 일치성지수와 균질성지수가 우수하였으며 정상조직 보호측면에서도 미미하지만 우수한 것으로 나타났다. 하지만 정확한 환자자세가 확보되지 않으면 부작용이 발생할 수 있다. 따라서, 기하학적으로 정확한 환자의 위치잡이를 수반한 Half beam의 적용은 선량적으로 유용할 수 있을 것으로 사료된다.

Keywords

References

  1. Central Cancer Registry Center. "Annual Report of the Central Cancer in Korea (2002.01-2002.12)", Vol.11, 2003
  2. Pera M, Pera M, "Recent changes in the epidemiology of esophageal cancer". Surg Oncol, Vol.10, pp.81-90, 2001 https://doi.org/10.1016/S0960-7404(01)00025-1
  3. Sons HU, Borchard F. "Cancer of the distal esophagus and cardia. Incidence, tumorous infiltration, and metastatic spread." Ann Surg, Vol.203, No.2, 203, pp.188-195, 1986 https://doi.org/10.1097/00000658-198602000-00013
  4. Koshy M, Esiashvilli N, Landry JC, et al. "Multiple management modalities in esophageal cancer: combined modality management approach". Oncologist, Vol.20, No.5, pp.147-159, 2004
  5. Kok TC, Siersema PD. "Neoadjuvant chemotherapy in operable esophageal squamous cell cancer: final report of a phase III multicenter randomized trial". Proc Am Clin Oncol, Vol.16, pp.277a, 1997
  6. Toita T, Ogawa K, Adachi G, et al. "Concurrent chemoradiotherapy for squamous cell carcinoma of thoracic esophagus: fesibility and outcome of large regional field and high-dose external beam boost irradiation." Jpn J Clin Oncol Vo.31, No.8, pp.375-381, 2001
  7. Chidel MA, Rice TW, Adelstein DJ, et al. "Resectable esophageal carcinoma: local control with neoadjuvant chemotherapy and radiation therapy". Radiology, Vol.213, Issue.1, pp.67-72, 1999 https://doi.org/10.1148/radiology.213.1.r99oc1767
  8. Briboulet JF, Gignoux M, Triboulet JP, et al. "Chemoradiotherapy followed by surgery compared with surgery alone in squamous cell cancer of the esophagus." N Engl J Med , Vol.337, pp.161-167, 1997 https://doi.org/10.1056/NEJM199707173370304
  9. Minsky BD. Cancer of the esophagus. In: Leibel SA, Phillips TL, eds. "Textbook of Radiation Oncology. 2nd ed." Philadelphia, PA: Saunders Co. pp.811-824, 2003
  10. ICRU, "International Commission on Radiation Units and Measurements." Report 62: Prescribing, Recording and Reporting Photon Beam Therapy (Supplement to ICRU Report 50), 1999
  11. Denttis AS. Esophagus. In: Perez CA, Brady LW, eds. "Principles and Practice of Radiation oncology. 4th ed." Philadelphia, PA: Lippincott Co. pp.1282-1304, 2004
  12. Tai P, Van Dyk J, Yu E, et al. "Variability of target volume delineation in cervical esophageal cancer". Int J Radiat Oncol Biol Phys, Vol.42, Issue.2, pp.277-288, 1998 https://doi.org/10.1016/S0360-3016(98)00216-8
  13. Raman NV, Small W Jr. "The role of radiation therapy in the management of esophageal cancer." Cancer Control. Vol.6, pp.53-62, 1999 https://doi.org/10.1177/107327489900600105
  14. Nedzi LA, Kooy HM, Alexander E 3rd, Svensson GK, Loeffler JS. "Dynamic field shaping for stereotactic radiosurgery: a modeling study". Int J Radiat Oncol Biol Phys Vol.25, pp.859-69, 1993 https://doi.org/10.1016/0360-3016(93)90316-N
  15. Anderson LL, Lad TE. "Autopsy findings in squamous cell carcinoma of the esophagus". Cancer, Vol.50, pp.1587-1590, 1982 https://doi.org/10.1002/1097-0142(19821015)50:8<1587::AID-CNCR2820500820>3.0.CO;2-S
  16. Akiyama H, Tsurumaru M, Kawamura T, et al. "Principles of surgical treatment for carcinoma of the esophagus: analysis of lymph node involvement." Ann Surg, No.194, pp.438-446, 1981
  17. Heeren PA, Jager PL, Bongaerts F, et al. "Detection of distant metastases in esophageal cancer with 18F-FDG PET." J Nuc Med, No.45, pp.980-987, 2004
  18. Aisner J, Forastiere A, Aroney R. "Patterns of recurrence for cancer of the lung and esophagus. In: Wittes RE, ed. Cancer treatment symposia: proceedings of the workshop on patterns of failure after cancer treatment," vol 2. Washington DC, PA: Department of Health and Human Services, No.87, 1983
  19. Stein HJ, Feith M, Bruecher BL, et al. "Early esophageal cancer: pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection." Ann Surg, No.242, pp.566-575, 2005
  20. Ji Young Jang, "The Outcome of Conventional External Beam Radiotherapy for Patients with Squamous Cell Carcinoma of the Esophagus", Int J Radiat Oncol, Vol.26, No.1, pp.17-23, 2008.