• Title/Summary/Keyword: growth behavior

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A Study on the Behavior of the Plane Stress Fracture Toughness - About the Compact Tension Specimen- (平面應力 破壞靭性値 擧動에 관한 硏究)

  • 송삼홍;고성위
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.10 no.6
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    • pp.937-946
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    • 1986
  • In this paper, the plane stress fracture toughness of low carbon steel with 3mm thickness is investigated for various specimen widths and crack ratios using the J integral. The experiments is carried out for the compact tension(CT) specimen on an Instron machine. For materials that may be approximated by the Ramberg and Osgood stress strain law, the relevant crack parameter like the J integral and load line displacement are approximately normalized. Crack driving forces in terms of J integral is computed using the above estimation scheme. Abtained results are summarized as follows. (1) The plane stress fracture toughness, J$_{c}$, is almost constant in the range 50-70mm of width. Hence J$_{c}$ can be obtained by using smaller specimen than ASTM standard. (2) Yoon's and Simpson's formular which considers crack growth in obtaining J integral show more consevative J than Rice's and Merkle's (3) J$_{c}$ is almost constant in the range 0.499-0.701 crack ratios tested. J$_{c}$ obtained by using Kumar's formular is 28.14kgf/mm for base metal specimen and 32.51kgf/mm for annealed. (4) Comparison of the prediction with actual experimental measurements by Yoon's formular show good agreement for several different-size specimens.

A Case of Smith-Lemli-Opitz Syndrome in DHCR7 Mutation (DHCR 7 유전자 돌연변이로 확진된 스미스-렘리-오피츠 증후군 1례)

  • Jeong, Yu Ju;Huh, Rimm;Kwun, Younghee;Lee, Jieun;Cho, Sung Yoon;Ki, Chang-Seok;Jin, Dong-Kyu
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.14 no.1
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    • pp.60-65
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    • 2014
  • Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disease caused by a defect in cholesterol biosynthesis. This mutation encodes 7-dehydrocholesterol reductase (DHCR7), which is located on chromosome 11q13. It is characterized by typical facial appearances, microcephaly, small up-turned nose, cleft palate, syndactyly, and is correlated with cardiac, gastrointestinal and genital malformations. There may also be mental retardation, behavioral problems and growth retardation. It causes a broad spectrum of effects, ranging from a mild disorder of learning and behavior to a lethal malformation. There are four reports of Smith-Lemli-Opitz syndrome in Korean children. Here, we describe a two months old female with microcephaly, toe syndactyly and a cleft soft palate who was diagnosed as SLOS with c. 1054 C>T (p.R352W) and c.907G>A (p. G303R) mutations.

A Study on the Behavior in the Corner Crack Propagation of Al-Alloy used for the Shipbuilding by the Corrosion Fatigue (부식피로에 의한 선박용 알루미늄 합금제 용접부의 균열 전파기동에 관한 연구)

  • Im, U-Jo;Lee, Jin-Yeol
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.24 no.4
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    • pp.164-171
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    • 1988
  • Recently with the rapid development in marine and shipbuilding industries such as marine structures, ships and chemical plants, it takes much interest in the study of corrosion fatigue characteristics that was close up an important role in mechanical design. In this study, characteristics of corner crack propagation on the base metal and heat affected zone of 5086 Al-Alloy was tested by using of a rotary bending fatigue tester and was investigated under the environments of specific resistance, $\rho$=25$\Omega$ cm and air. The corrosion fatigue crack initiation and corrosion fatigue life sensitivity were quantitatively inspected for 5086 Al-Alloy in the specific resistance, $\rho$=25$\Omega$ cm. Main results obtained are as follows: (1) The corrosion sensitivity of heat affected zone under specific resistance, $\rho$=25$\Omega$cm shows approximately 1.69~2.22 and corrosion sensitivity of base metal is more susceptible than that of heat affected zone. (2) The corrosion fatigue life sensitivity on heat affected zone decreases eminently than that of initial corrosion fatigue crack. (3) The characteristics of quarter elliptical corner crack propagation shows that depth crack is more grown than surface crack at crack initiation, but the surface crack is more propagated than depth crack as the crack propagation is increased. (4) The surface crack and depth crack growth on heat affected zone by softness show delayed phenomenon than that of base metal.

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Shoot multiplication kinetics and hyperhydric status of regenerated shoots of gladiolus in agar-solidified and matrix-supported liquid cultures

  • Gupta, S. Dutta;Prasad, V.S.S.
    • Plant Biotechnology Reports
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    • v.4 no.1
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    • pp.85-94
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    • 2010
  • In vitro shoot regeneration of gladiolus in three different culture systems, viz., semi-solid agar (AS), membrane raft (MR), and duroplast foam liquid (DF) cultures was evaluated following the kinetics of shoot multiplication and hyperhydricity at optimized growth regulator combinations. Compared to the AS system, matrixsupported liquid cultures enhanced shoot multiplication. The peak of shoot multiplication rate was attained at 18 days of incubation in the MR and DF systems, whereas the maximum rate in the AS system was attained at 21 days. An early decline in acceleration trend was observed in liquid cultures than the AS culture. The hyperhydric status of the regenerated shoots in the different culture systems was assessed in terms of stomatal attributes and antioxidative status. Stomatal behavior appeared to be normal in the AS and MR systems. However, structural anomaly of stomata such as large, round shaped guard cells with damage in bordering regions of stomatal pores was pronounced in the DF system along with a relatively higher $K^+$ ion concentration than in the AS and MR systems. Antioxidative status of regenerated shoots was comparable in the AS and MR systems, while a higher incidence of oxidative damages of lipid membrane as evidenced from malondialdehyde and ascorbate content was observed in the DF system. Higher oxidative stress in the DF system was also apparent by elevated activities of superoxide dismutase, ascorbate peroxidase, and catalase. Among the three culture systems, liquid culture with MR resulted in maximum shoot multiplication with little or no symptoms of hyperhydricity. Shoots in the DF system were more prone to hyperhydricity than those in the AS and MR systems. The use of matrix support such as membrane raft as an interface between liquid medium and propagating tissue could be an effective means for rapid and efficient mass propagation with little or no symptoms of hyperhydricity.

Effect of N2 flow rate on growth and photoluminescence properties of GaN nanorods grown by using molecular beam epitaxy (분자선 에피택시를 이용하여 GaN 나노로드를 성장시 구조 및 광학적인 특성에 미치는 N2의 양의 효과)

  • Park, Y.S.
    • Journal of the Korean Vacuum Society
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    • v.16 no.4
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    • pp.298-304
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    • 2007
  • We have studied the effect of $N_2$ flow rate on the structural and optical properties of GaN nanorods grown on (111) Si substrates by radio-frequency plasma-assisted molecular-beam epitaxy. The hexagonal shape nanorods with lateral diameters from 80 to 190 nm with increasing $N_2$ flow rate from 1.1 to 2.0 sccm are obtained. However, the ratio of length (thickness) and compact region increases with increasing $N_2$ flow rate up to 1.7 sccm and then saturate. From the photoluminescence, free exciton transition is clearly observed for GaN nanorods with low $N_2$ flow rate. And the PL peak energies are blue-shifted with decreasing diameter of the GaN nanorods due to size effect. Temperature-dependent photoluminescence spectra for the nanorods with $N_2$ flow rate of 1.7 sccm show an abnormal behavior like "S-shape" with increasing temperature.

Effect of Crystallographic Orientation on Fracture Mechanism of Ni-Base Superalloy

  • Han, Chang-Suk;Lim, Sang-Yeon
    • Korean Journal of Materials Research
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    • v.25 no.11
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    • pp.630-635
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    • 2015
  • The fatigue strength of a nickel-base superalloy was studied. Stress-controlled fatigue tests were carried out at $700^{\circ}C$ and 5 Hz using triangular wave forms. In this study, two kinds of testing procedures were adopted. One is the conventional tension-zero fatigue test(R = 0). The other was a procedure in which the maximum stress was held at 1000 MPa and the minimum stress was diverse from zero to 1000 MPa at 24 and $700^{\circ}C$. The results of the fatigue tests at $700^{\circ}C$ indicate that the fracture mechanism changed according to both the mean stress and the stress range. At a higher stress range, ${\gamma}^{\prime}$ precipitates are sheared by a/2<110> dislocation pairs coupled by APB. Therefore, in a large stress range, the deformation occurred by shearing of ${\gamma}^{\prime}$ by a/2<110> dislocations, which brought about crystallographic shear fracture. As the stress range was decreased, the fracture mode gradually changed from crystallographic shear fracture to gradual growth of fatigue cracks. At an intermediate stress range, as it became more difficult for a/2<110> dislocation pairs to shear ${\gamma}^{\prime}$ particles, cracks started to propagate in the matrix, avoiding the harder ${\gamma}^{\prime}$ particles. High mean stress induced creep deformation, that is, ${\gamma}^{\prime}$ particles were sheared by {111}<112> slip systems, which led to the formation of stacking faults in the precipitates. Thus, the change in fracture mechanism brought about the inversion of the S-N curves.

Analysis of Relative Importance of Key Performance Indicators for Center for Child-Care Foodservice Management through Analytic Hierarchy Process (AHP) (계층적 분석법(AHP)을 이용한 어린이급식관리지원센터 핵심성과지표(KPI)의 상대적 중요도 분석)

  • Jeong, Yun-Hui;Chae, In-Sook;Yang, Il-Sun;Kim, Hye-Young;Lee, Hae-Young
    • Korean Journal of Community Nutrition
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    • v.18 no.2
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    • pp.154-164
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    • 2013
  • The objectives of this study were to assign reasonability to importance of weight selection issue in key performance indicator for performance evaluation of Centers for Child-care Foodservice Management (CCFSM) developed by using Balanced Scorecard (BSC), to draw key performance indicator (KPI) by perspective and to analyze differences in recognition on importance. From September 25 to October 9, 2012, we conducted a questionnaire-based study via e-mail, targeting chiefs and team leaders of nationwide 21 CCFSMs (43 persons), officials of local governments where CCFSM was established (21 persons), officials of Korea Food and Drug Administration (2 persons) and foodservice management experts (27 persons) in order to estimate the relative importance on 4 perspectives and 14 KPIs and analyzed its results by using 61 collected data. The results showed that relative importance of perspectives was estimated in order of importance as follows: business performance (0.3519), customer (0.3393), resource (0.1557), learning and growth (0.1531). Relative importance of KPIs was in order of importance as follows: Evaluation of sanitary management level in child-care foodservice facilities (0.1327), Level of customer recognition and behavior improvement (0.1153), performances of round visiting inspection on foodservice, sanitary, safety management, and foodservice consulting (0.0913). Our results showed that the recognition differences exist on the relative importance of perspectives and KPIs between officials of CCFSM, KFDA, local government and foodservice management experts. These observations will form the basis for developing evaluation systems, and it is considered that performance indicators developed on this basis will suggest direction of operation which CCFSM will have to perform.

Inducing stress-strain relationship for element simulation of cyclic triaxial test on unsaturated soil (불포화토에 대한 반복삼축압축시험의 요소시뮬레이션을 위한 응력-변형율 관계의 수립)

  • Lee, Chung-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.8
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    • pp.5654-5663
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    • 2015
  • In the unsaturated soil, suction, the negative pore water pressure leads to increases of the yield stress and the plastic shear stiffness of the soil skeleton due to the growth in interparticle stress. Therefore, in this study, the stress-strain relationship based on cyclic elasto-plastic constitutive model extended for unsaturated soil considering the 1st and the 2nd yield functions was induced in order to account for these effects of suction under the dynamic loading condition such as the earthquake. Through the program code considering this relationship and the routine of the cyclic loading with the reversion of loading direction, the numerical simulation of the cyclic triaxial test under the unsaturated condition would be possible. It is expected that the results of this study possibly contribute to the accuracy improvement on the prediction of unsaturated soil behavior under the dynamic loading condition.

Comparison of Food and Nutrient Consumption Status between Displaced North Korean Children in South Korea and South Korean Children (한국 거주 북한이탈 어린이와 남한 어린이의 식품 및 영양소 섭취 현황 비교)

  • Lee, Soo-Kyung;Nam, So-Young
    • Korean Journal of Community Nutrition
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    • v.17 no.4
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    • pp.407-418
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    • 2012
  • Many displaced North Koreans (NK) are living in South Korea (SK); however nutrition research with the displaced NK is limited. This study examined food and nutrient consumption status of displaced NK children (6-18 year-old) currently living in SK. A total of 154 children were recruited, and a pre-tested dietary behavior questionnaire, food frequency questionnaire, 24-hr recall method were used. Sex- and age-matched SK children (n = 462) randomly selected from 2009-2010 Korea National Health and Nutrition Examination Survey were used as the comparison group. This study found that more NK children skipped breakfast (37%) and dinner (11%), and ate breakfast (38.8%) and dinner (18.2%) without family members than SK children. Many NK children reported that they rarely ate bread, rice cake, hamburger, pizza, fried food, candy. NK children consumed significantly less energy and nutrients (except calcium) and obtained more energy from fat and protein than SK children. Overall index of nutrient quality in NK children, however, was generally good. Length of stay in SK and breakfast skipping rates were significantly associated with lower diet quality. Therefore, nutrition education with displaced NK children should target those who recently came to SK. How to incorporate "new" foods, generally high in energy, sugar, or fat, in healthy ways and importance of breakfast should be emphasized. The growth patterns of the displaced NK children who were born and raised in food-deprived environments and will grow in food-affluent environments of SK should be monitored for health promotion of the NK children and for nutrition policy of the future united Korea.

Dynamic Behavior of Regulatory Elements in the Hierarchical Regulatory Network of Various Carbon Sources-Grown Escherichia coli

  • Lee, Sung-Gun;Hwang, Kyu-Suk;Kim, Cheol-Min
    • Journal of Microbiology and Biotechnology
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    • v.15 no.3
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    • pp.551-559
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    • 2005
  • The recent rapid increase in genomic data related to many microorganisms and the development of computational tools to accurately analyze large amounts of data have enabled us to design several kinds of simulation approaches for the complex behaviors of cells. Among these approaches, dFBA (dynamic flux balance analysis), which utilizes FBA, differential equations, and regulatory events, has correctly predicted cellular behaviors under given environmental conditions. However, until now, dFBA has centered on substrate concentration, cell growth, and gene on/off, but a detailed hierarchical structure of a regulatory network has not been taken into account. The use of Boolean rules for regulatory events in dFBA has limited the representation of interactions between specific regulatory proteins and genes and the whole transcriptional regulation mechanism with environmental change. In this paper, we adopted the operon as the basic structure, constructed a hierarchical structure for a regulatory network with defined fundamental symbols, and introduced a weight between symbols in order to solve the above problems. Finally, the total control mechanism of regulatory elements (operons, genes, effectors, etc.) with time was simulated through the linkage of dFBA with regulatory network modeling. The lac operon, trp operon, and tna operon in the central metabolic network of E. coli were chosen as the basic models for control patterns. The suggested modeling method in this study can be adopted as a basic framework to describe other transcriptional regulations, and provide biologists and engineers with useful information on transcriptional regulation mechanisms under extracellular environmental change.