• Journal of the Korea Society of Computer and Information
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• v.21 no.4
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• pp.115-121
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• 2016

The purpose of this paper is to study the influence of hypersensitiveness in accident reports and usefulness on admission of atomic power generation. By the result of study we can look forward to understanding obstacles and promotion factors in constructing atomic power plants. The results of hypothesis testing can be summarized as follows: First, the hypothesis that hypersensitiveness in accident reports has a plus effect on reliability is accepted. Secondly, the hypothesis that hypersensitiveness in accident reports has a plus effect on anxiety is accepted. Thirdly, the hypothesis that reliability has a plus effect on anxiety is accepted. Fourthly, the hypothesis that reliability has a minus effect on receptiveness is accepted. Fifthly, the hypothesis that anxiety has a minus effect on receptiveness is accepted. Sixthly, the hypothesis that usefulness has a minus effect on necessity is accepted. Seventhly, the hypothesis that usefulness has a plus effect on receptiveness is rejected. Eighthly, the hypothesis that necessity has a minus effect on receptiveness is accepted.

• Environmental Mutagens and Carcinogens
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• v.19 no.2
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• pp.116-121
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• 1999

Quercetin and its glycosides showed a strong free radical scavenging effect to DPPH radical generation. However, there were not big differences between quercetin aglycone and glycosides under experimental condition of this study. On the other hand, quercetin had pro-oxidant effect in bleomycin-dependent DNA assay. Quercetin aglycone and its glycosides, quercitrin inhibited $H_2$$O_2$- induced DNA damage in CHL cells. They also have an anticlastogenicity toward DNA breakage agent by radical generation like bleomycin. These results indicate that quercetin aglycone and its glycosides are capable of protecting the free radical generation induced by reactive oxygen species like $H_2$$O_2$. The mechanism of inhibition in hydrogen peroxide-induced genotoxicity may be due to their free radical scavenging properties. Therefore, quercetin aglycone and its glycosides may be useful chemopreventive agents by protecting of free radical generation which are involved in carcinogenesis and aging. However, quercetin and its glycosides must also carefully examined for pro-oxidant properties before being proposed for use in vivo.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.477-481
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• 2006

A clinical report indicates that 'Geijibokryunghwan(GBH) is very effective in treating thrombosis in those patients who have difficulties with more conventional antithrombotic drugs. The isolation and identification of various compounds from this plant and the same genus have been reported by several groups. However, the pharmaceutical effect of the GBH on superoxide generation in human neutrophils has not been studied. In the present report, we investigated the possibility of using herbal medicine as an alternative therapy. In particular, we studied tremor in antiatheroscleosis. In this report, we shows the GBH extract can be used as a potential atherosclerosis preventive agent in human. The effect of GBH on stimulus-induced superoxide generation and phosphorylation of tyrosine residues of protein in human neutrophils was investigated. In a conclusion, GBH suppressed tyrosine phosphorylase in a dose-dependent manner, and may have pharmacoceutical applications. These data suggest that GBH extracts merits investigation as a potential anti-atherosclerogenic agent in humans.

• The Journal of Korean Medicine
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• v.30 no.6
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• pp.17-26
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• 2009

Objectives: Little information is available regarding the effect of Lycii cortex radicis (LCR) on cell viability in glioma cells. This study was therefore undertaken to examine the effect of LCR on cell survival in U87MG human glioma cells. Methods: Cell viability and cell death were estimated by MTT assay and trypan blue exclusion assay, respectively. Reactive oxygen species (ROS) generation was measured using the fluorescence probe DCFH-DA. Activation of Akt and extracellular signal-regulated kinase (ERK) and activation of caspase-3 were estimated by Western blot analysis. Results: LCR resulted in apoptotic cell death in a dose- and time-dependent manner. LCR increased reactive oxygen species (ROS) generation and LCR-induced cell death was also prevented by antioxidants, suggesting that ROS generation played a critical role in LCR-induced cell death. Western blot analysis showed that LCR treatment caused down-regulation of Akt and ERK. The LCR-induced cell death was increased by the inhibitors of Akt and ERK. Activation of caspase-3 was stimulated by LCR and caspase inhibitors prevented the LCR-induced cell death. Conclusion: These findings suggest that LCR results in human glioma cell death through a mechanism involving ROS generation, down-regulation of Akt and ERK, and caspase activation.

• Journal of Welding and Joining
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• v.29 no.2
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• pp.56-63
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• 2011

his paper aimed to understand the residual stress in the dissimilar metal welds of nuclear power plant. Two kinds of residual stress were considered, which caused by welding and machining. Residual stress due to mechanical machining was measured by hole-drilling technique and x-ray diffraction method for the SA508 and F316L. Weld residual stress at dissimilar metal weld between SA508 and F316L was evaluated by FEA. Residual stress profiles were obtained for the inside surface and through thickness of welds. Machining effect was also analyzed by FEA. According to the residual stress measurement, it was observed that mechanical machining can generate tensile stress on the surface of the test material. However, FEA results showed that mechanical machining did not increase the tensile stress on the surface of weld region. Further study with more elaborate measurement and numerical analysis is required to identify the effect of machining on residual stress in the dissimilar metal weld region.

• The Journal of Economics, Marketing and Management
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• v.11 no.4
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• pp.41-52
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• 2023

Purpose: The study examines the effect of TechTubers' unboxing videos on consumer buying behavior by highlighting the role of product touch, visual and verbal sensory cues. The study integrates the vicarious touch and the dual coding theory to analyze the Smartphone purchase behavior of Generation Z. Research design, data and methodology: The study collected data from 349 respondents who were viewers of YouTube unboxing videos. A structured questionnaire using a 5-point Likert scale was employed as a survey instrument. Convenience sampling technique was utilized to select the samples. The data were analyzed using structural equation modeling (SEM). Results: Results reveal that vicarious touch and verbal description have a statistically significant positive effect on Generation Z's purchase intention of Smartphone. Moreover, purchase intention positively affects Generation Z's actual purchase behavior of Smartphone. However, the visual images did not significantly affect purchase intention. Conclusions: The study offers significant theoretical and practical implications. The study adds new knowledge to the extant literary field by highlighting the impact of digital product presentation in the form of Unboxing videos on purchase intention for technology products. Moreover, the study suggests content sponsorship and advertising opportunities for marketers in collaboration with the TechTubers on YouTube unboxing video platform.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.5
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• pp.1494-1504
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• 2004

The present paper reports the effects of Hwaotang an atherosclerosis using a spontaneous experimental model, We have also investigated the pharmacological effect of Hwaotang on collagen- and ADP-induced blood platelet aggregation, thrombin-induced conversion of fibrinogen and fibrinolysis in in vitro experiments, and various effects on stimuli-induced superoxide generation in human neutrophils. Hwao-tang was shown to have inhibitory effect on collagen- and ADP-induced blood platelet aggregation, on thrombin-induced conversion of fibrinogen to fibrin and on the activity of plasminogen or plasmin. Hwao-tang also significantly inhibited fMLP-induced superoxide generation in a concentration-dependent manner, but not that induced by arachidonic acid. Hwao-tang inhibited neutrophil functions, including degranulation, superoxide generation, and leukotriene B4 production, without any effect on 5-lipoxygenase activity. In conclusion, the protection of extracts of Hwao-tang on the ischemic infarction induced artificially might be involved to their inhibition of thrombotic action. The results also indicate that Hwao-tang exerts the effects on superoxide generation related to the inhibition of neutrophil functions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.2
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• pp.1084-1091
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• 2015

Purpose: This study examined the level of retirement preparation and quality of life and to identify the relationship among work, retirement preparation and quality of life in the baby boomer generation. Methods: The subjects of this study were 204 people in the baby boomer generation in Changwon city, Gyeongsangnam-do. Results: Work affected the quality of life in the Changwon city baby boomer generation through job satisfaction and social interaction in the workplace. Retirement preparation through the workplace also appeared to have a partial mediating effect on the quality of life. Conclusion: The results suggest that work(satisfaction and social network) can affect the quality of life of the baby boomer generation. Furthermore, the retirement preparation of the baby boomer generation has a partial mediation effect on the overall quality of life.

• Journal of Digital Convergence
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• v.15 no.10
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• pp.501-512
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• 2017

The purpose for this study was to figure out the effect factors of baby boom generation' leisure and preparation for old aged on life satisfaction and moderated regression for spouse support. A survey of baby boom generation who are living in Seoul and metropolitan areas was conducted 406 collected data. The results are as follows. First, Leisure had influences on life satisfaction. Second, Preparation for old aged and independent leisure had a positive effect on life satisfaction. Third, Preparation for old aged had mediate leisure on the effect on life satisfaction. Fourth, spouse support. had moderated regression leisure on the effect on life satisfaction. Fifth, Moderated regression for spouse support. had a negative effect on life satisfaction mediated economic preparation for old aged and had a positive effect on life satisfaction mediated physical preparation for old aged.

• Journal of Fashion Business
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• v.25 no.4
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• pp.109-124
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• 2021

The millennial generation, which has emerged as one of the strongest influence and consumption power, pursues happiness of the present centering on "I"; consumes luxury products for themselves. The purpose of this study was to evaluate how the narcissism and materialism of the millennial generation affect the compensatory consumption of luxury products in negative situations and the moderating effect of self-control. This study included 315 millennial males and females living in Seoul and Gyeonggi area. Frequency analysis, reliability analysis, multiple regression analysis, and hierarchical regression analysis were conducted using SPSS 25.0 statistical program. Based on our findings, narcissism and materialism had a statistically significant effect on compensatory consumption under positive situations. However, while materialism had a statistically significant effect on compensatory consumption under negative situations, narcissism did not have a statistically significant effect on compensatory consumption under negative situations. Notably, self-control had a moderating effect in the influence of materialism on compensatory consumption under negative situations; narcissism did not. This study holds academic significance as the concept of compensatory consumption and self-control can be applied to the apparel study. Moreover, this study provides practically significant ideas on compensatory consumption and therefore marketing of luxury brands, based on consumers' characteristics.