Environmental Mutagens and Carcinogens (한국환경성돌연변이발암원학회지)
- Volume 19 Issue 2
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- Pages.116-121
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- 1999
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- 1225-6307(pISSN)
Antigenotoxicity and Action Mechanism of Quercetin and its Glycosides against Oxidative DNA Damage
Oxidative DNA 손상에 대한 Quercetin 및 그 배당체들의 유전독성억제효과와 작용기전
Abstract
Quercetin and its glycosides showed a strong free radical scavenging effect to DPPH radical generation. However, there were not big differences between quercetin aglycone and glycosides under experimental condition of this study. On the other hand, quercetin had pro-oxidant effect in bleomycin-dependent DNA assay. Quercetin aglycone and its glycosides, quercitrin inhibited
Keywords
- Quercetin Aglycone and its glycosides;
- Hydrogen peroxide;
- Free radical scavenging effect;
- anticlastogenicity;
- Flavonoids;
- Antigenotoxicity;
- Comet assay;
- Micronucleus test;
- Cancer chemopreventive agent