• Title/Summary/Keyword: fundamental domains

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Research Trends in Large Language Models and Mathematical Reasoning (초거대 언어모델과 수학추론 연구 동향)

  • O.W. Kwon;J.H. Shin;Y.A. Seo;S.J. Lim;J. Heo;K.Y. Lee
    • Electronics and Telecommunications Trends
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    • v.38 no.6
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    • pp.1-11
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    • 2023
  • Large language models seem promising for handling reasoning problems, but their underlying solving mechanisms remain unclear. Large language models will establish a new paradigm in artificial intelligence and the society as a whole. However, a major challenge of large language models is the massive resources required for training and operation. To address this issue, researchers are actively exploring compact large language models that retain the capabilities of large language models while notably reducing the model size. These research efforts are mainly focused on improving pretraining, instruction tuning, and alignment. On the other hand, chain-of-thought prompting is a technique aimed at enhancing the reasoning ability of large language models. It provides an answer through a series of intermediate reasoning steps when given a problem. By guiding the model through a multistep problem-solving process, chain-of-thought prompting may improve the model reasoning skills. Mathematical reasoning, which is a fundamental aspect of human intelligence, has played a crucial role in advancing large language models toward human-level performance. As a result, mathematical reasoning is being widely explored in the context of large language models. This type of research extends to various domains such as geometry problem solving, tabular mathematical reasoning, visual question answering, and other areas.

Molecular Mechanisms of Inner Ear Development and Disease

  • Hayoung Yang;Jiho Ryu;Sungbo Shim
    • Biomedical Science Letters
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    • v.29 no.3
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    • pp.95-102
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    • 2023
  • The inner ear constitutes a complex organ responsible for auditory perception and equilibrium. It comprises diverse cellular entities operating collaboratively to perceive and transmit sensory information to the brain. Inner ear disease is a sophisticated and multifactorial scenario substantially impacting the quality of life of affected individuals. Gaining insights into the developmental process of the inner ear is crucial for diagnosing and treating inner ear diseases, which can lead to hearing loss and impaired balance. Recent research in inner ear development and associated pathophysiology has focused on several pivotal domains, including identifying new genes and signaling pathways involved in inner ear development, using stem cells for inner ear regeneration, and developing novel therapies for inner ear diseases. Recent advances in genetics research have shed new light on the fundamental etiologies of inner ear diseases, with a growing body of evidence suggesting that genetic mutations might exert a pivotal influence on the development and progression of this condition. In this review, we have delved into certain common genetic mutations linked to inner ear disorders. We also discussed ongoing research endeavors and future directions for understanding the genetic mechanisms underlying this condition and potential therapeutic avenues.

A Survey on Situation-related Communication Educational Needs for Novice Intensive Care Unit Nurses (중환자실 신규 간호사의 의사소통 상황 관련 교육 요구도 조사)

  • Hwang, Wonjung;Ha, Jeongmin;Park, Dahye
    • Journal of Korean Critical Care Nursing
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    • v.17 no.1
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    • pp.17-29
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    • 2024
  • Purpose : This study sought to investigate novice nurses' communication education needs in the intensive care unit (ICU) using Importance-Performance Analysis (IPA) and Borich's need assessment model. This study identified communication challenges in clinical settings to develop a simulation program that enhances communication competencies based on educational requirements. Methods : A descriptive research design and a self-report questionnaire were used. The latter was developed and administered to 121 novice nurses with less than one year of experience in the ICU at various university hospitals in Korea. Data were collected via the online open chatroom from June 24th to July 28th, 2023. The communication education needs were identified using descriptive statistics, t-tests, IPA, and Borich's needs assessment model. Text analysis was used to categorize the participants' communication experience. Results : The results revealed that "communication with physicians," "communication with patients," and "communication with nurse on another shift" domains contained the most substantial educational needs for novice nurses working in the intensive care units. Conclusion : The results provide fundamental data for developing and enhancing customized communication education programs for novice ICU nurses. This valuable information could help ICU nurses and educators improve new nurses' communication skills, which would ultimately contribute to the advancement of nursing education and clinical practice.

A parametric investigation on seismic performance of ageing Sarıyar dam

  • Ahmad Yamin Rasa;Ahmet Budak
    • Structural Engineering and Mechanics
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    • v.91 no.2
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    • pp.123-133
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    • 2024
  • The assessment of seismic behavior and seismic performance of ageing Sarıyar concrete gravity dam constructed on Sakarya River in Türkiye is the main focus of this paper. For this purpose, the impact of sediment domain, ageing of concrete material under the impact of chemical and mechanical actions, and dam-water-sediment interaction are included in the two-dimensional (2D) finite element (FE) model developed in FORTRAN 90 environment. In the FE model, the dam and age dependent sediment domains are modeled by solid elements, while reservoir domain is modeled by Lagrangian fluid elements. The radiation of reflected waves to the unbounded water domain is modeled by infinite Lagrangian fluid elements, while unbounded sediment domain is modeled by infinite solid elements. The coupled system was assumed to be under the simultaneous impact of Vertical (V) and Horizontal (H) ingredients of 1976 Koyna earthquake and the coupled system was analyzed in Laplace domain by direct method. Due to the deterioration of the concrete, the H and V displacement responses together with the fundamental period of the body, elongate throughout the lifetime and this reduce the seismic safety of the dam. It was deduced that the ageing dam body will not experience major damages under the Koyna earthquake both at the earlier and later ages. Furthermore, at the heel of the dam, the hydrodynamic pressure responses are decreased by rising the sediment domain depth.

Analysis of Science Educational Contents of Singapore, Canada and US Focused on the Integrated Concepts (통합개념을 중심으로 한 싱가포르, 캐나다와 미국의 과학교육과정 내용 요소 분석)

  • Lee, Yoonha;Yoon, Heojeong;Song, Joo-Yeon;Bang, Dami
    • Journal of The Korean Association For Science Education
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    • v.34 no.1
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    • pp.21-32
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    • 2014
  • The feasibility of integrated concepts as a key element in designing integrated science curriculum has been investigated by analysing science contents included in performance expectations stated at different grades. The science curriculum of Singapore and the state of Ontario in Canada, and next generation of science standard (NGSS) were selected. Each of them presents theme, fundamental concepts, and crosscutting concepts, which has the characteristics of integrated concepts proposed in the study. Analysis showed that theme, fundamental concepts, and crosscutting concepts were influenced by the characteristics of each curriculum. In addition, science contents related to integrated concepts at different grades varied with the nature of integrated concepts. Based on results, some suggestions were made. First, the total number of integrated concepts should be considered for designing integrated curriculum. Second, the nature of integrated concepts and science contents associated with the integrated concepts should be considered. The integrated concepts should be vast and deep enough in the meaning to contain various content knowledge of different science domains. Third, it should be considered that how the integrated concepts have to be presented at different grades.

Interactions between Science, Technology and Innovation Policy Issues and Academic Research: A Case of the Qualitative Content Analysis on Major Newspapers and Academic Journals between 2008-2011 (과학기술혁신정책 이슈와 학술연구 간의 상호관계연구: 2008~2011년 주요 일간지와 학술지에 대한 질적내용분석을 중심으로)

  • Choi, Hyundo
    • Journal of Korea Technology Innovation Society
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    • v.17 no.4
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    • pp.763-785
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    • 2014
  • Science, technology and innovation policy (STI policy) is a result of the interactions between the social issues and academic research. Understanding the interactions of the STI policy between the social issues and academic research can throw some light on designing better policies and enhancing the social value of academic research. Thus, this paper explores the interactions of the STI policy between the social issues and academic research using the qualitative content analysis of major newspapers and journal articles in Korea. We have three major findings. First, on the one hand, academic research rose after uprising changes in the STI policy issues in the society. Second, on the other hand, social issues on STI policy were influenced by academic research reflecting the fundamental changes in the Korean innovation system and the nature of technology. Third, there are strong policy demands regarding the role of the STI policy for society and for traditional economic domains, but relevant research is scarce up to now. These findings contribute to uncovering the potential policy domains and agendas for policy makers and researchers.

How Does Giftedness Coexist with Autistic Spectrum Disorders (ASD)? Understanding the Cognitive Mechanism of Gifted ASD (영재성과 자폐성장애는 어떻게 공존하는가? 자폐성장애 영재의 인지메카니즘에 대한 이해)

  • Song, Kwang-Han
    • Journal of Gifted/Talented Education
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    • v.21 no.3
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    • pp.595-610
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    • 2011
  • It is hard to understand the coexistence of giftedness and disorder in an individual, but the twice-exceptional is widely recognized now. Gifted autistic spectrum disorder is one of its subtypes in which giftedness exists with autistic spectrum disorder (ASD) simultaneously. Like other constructs including giftedness, the nature of gifted ASD has not been understood in a fundamental and wholistic manner. This paper suggests a cognitive mechanism of gifted ASD based on the integrated model of human abilities(Song, 2009; Song & Porath, 2005), which explains how giftedness coexists with ASD and interacts with each other, producing the characteristics of gifted individuals with ASD. According to the suggested mechanism, the excessive growth of mental spaces in the brain may cause ASD. The over-grown mental spaces result in excessively strong short-term sensory memory and better facility of processing, promoting internal cognitive activities on one hand, but relative lack of cognitive activities in the real world space results in ASD symptoms on the other hand. The cognitive structure of gifted ASD students also contributes to the presentation of giftedness in specific domains. This study suggests that gifted individuals with ASD need to be discouraged from fully engaging in domains they are interested in or the most confident of, rather to be encouraged to invest their giftedness to overcome their ASD symptoms. This study also provides new perspectives on theoretical and educational approaches for gifted ASD.

How does stereology help to inform translation from neuroscience to OT? (입체해석학을 통해 신경과학의 정보를 작업치료학에 어떻게 전달할수 있을까?)

  • Park, Ji-Hyuk;Lee, Joo-Hyun;Park, Jin-Hyuck
    • Therapeutic Science for Rehabilitation
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    • v.3 no.2
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    • pp.5-48
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    • 2014
  • Introduction : One of the important domains in OT is performance skills which include sensory perceptual skills, motor and praxis skills, emotional regulation skills, cognitive skills, and communication/social skills. All of these skills are support ed by integrated neurological processes. Body : Stereology robust tool when employed to investigate morphological changes in neurons, cortex area, and specific parts of brain involved in special brain function. Stereology is an interdisciplinary field focused or analyzing biological tissue with the three-dimensional interpretation of planer sections by using estimating method and mathematically unbiased sampling. With the unbiased stereological method based on probability theory, researchers can estimate morphological and anatomical changes in biological reference areas accurately and efficiently. Changes in anatomical and cytoarchitectural parameters, such as volume, number, and length, affect specific brain function related to the brain area. Occupational therapists provide treatment to improve functions for participation of occupation in neurological disorder. The functional improvements in neurological disorder reflect neurobiological changes because functional difficulties, such as motor cognitive disorder, are due to neurological disturbances. Thus, combination of two kinds of evidence, neurological changes and functional improvement, provide fundamental evidence for OT intervention in neurological disorder. Even though most of stereological studies are in animal model and in postmortem human because of practical and ethical issues, stereology provides fundamental knowledge to support OT theory and practice. Conclusion : Therefore, stereology informs translation from neuroscience to OT based on structure-function relationship in performance skills and experience-dependent neural plasticity.

Solute Carrier SLC41A1 'A MINI REVIEW'

  • Basnet Hom Bahadur
    • Environmental Mutagens and Carcinogens
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    • v.25 no.2
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    • pp.60-65
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    • 2005
  • The human solute carrier, SLC41Al, is a $Mg^{2}+$ transporter that is regulated by extracellular magnesium. Although intracellular magnesium plays a fundamental role in cellular metabolism, little is known about how $Mg^{2}+$ is taken up and controlled by cells. Magnesium plays a fundamental role in cellular metabolism so that its control within the body is critical. Magnesium homeostasis is principally a balance between intestinal absorption of dietary magnesium and renal excretion of urinary magnesium. The kidney, mainly the distal convoluted tubule, controls magnesium reabsorption. Although renal reabsorption is under the influence of many hormones, selective regulation of magnesium transport is due to intrinsic control involving transcriptional processes and synthesis of transport proteins. Using microarray analysis, identification of the genetic elements involved with this transcriptional control has been begun. SLC41A1(GenBank Accession No. AJ514402), comprises 10 putative transmembrane domains, two of which are highly homologous to the integral membrane part of the prokaryote transports $Mg^{2}+$ and other divalent cations $Sr^2+,\;Zn^2+,\;Cu^2+,\;Fe^2+,\;Co^2+,\;Ba^2+,\;and\;Cd^2+,\;but\;not\;Ca^2+,\;Mn^2+,\;and\;Ni^2+.$ Transport of $Mg^{2}+$ by SLC41Al is rheogenic, voltage dependent, and not coupled to Na or Cl. Expressed SLC41Al transports a range of other divalent cations: $Mg^{2+},\;Sr^{2+},\;Zn^{2+},\;Cu^{2+},\;Fe^{2+},\;Co^{2+},\;Ba^{2+},\;and\;Cd^{2+}$. The divalent cations $Ca^{2+},\;Mn^{2+},\;and\;Ni^{2+}$and the trivalent ion $Gd^{3+}$ did not induce currents nor did they inhibit $Mg^{2+}$ transport. The nonselective cation $La^{3+}$ abolishes $Mg^{2+}$ uptake. Computer analysis of the SLC41Al protein structure reveals that it belongs to MgtE protein family & suggested that the human solute carrier, SLC41Al, might be a eukaryotic $Mg^{2+}$ transporter closely related $(60-70\%)$ protein encoded by SLC41A2 is a $Mg^{2}+$ transporter that might be involved in magnesium homeostasis in epithelial cells also transports a range of other divalent cations: $Ba^2,\;Ni^2,\;CO^2,\;Fe^2,\;or\;Mn^2,\;but\;not\;Ca^2,\;Zn^2,\;or\;Cu^{2+}$ that may have related functional properties.

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A Framework for Time Awareness System in the Internet of Things (사물인터넷에서 시각 정보 관리 체계)

  • Hwang, Soyoung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.6
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    • pp.1069-1073
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    • 2016
  • The Internet of Things (IoT) is the interconnection of uniquely identifiable embedded computing devices within the existing Internet infrastructure. IoT is expected to offer advanced connectivity of devices, systems, and services that goes beyond machine-to-machine communications and covers a variety of protocols, domains, and applications. Key system-level features that IoT needs to support can be summarized as device heterogeneity, scalability, ubiquitous data exchange through proximity wireless technologies, energy optimized solutions, localization and tracking capabilities, self-organization capabilities, semantic interoperability and data management, embedded security and privacy-preserving mechanisms. Time information is a critical piece of infrastructure for any distributed system. Time information and time synchronization are also fundamental building blocks in the IoT. The IoT requires new paradigms for combining time and data. This paper reviews conventional time keeping mechanisms in the Internet and presents issues to be considered for combining time and data in the IoT.